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P20142

- PEPC_HUMAN

UniProt

P20142 - PEPC_HUMAN

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Protein

Gastricsin

Gene

PGC

Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 5 out of 5- Experimental evidence at protein leveli

Functioni

Hydrolyzes a variety of proteins.

Catalytic activityi

More restricted specificity than pepsin A, but shows preferential cleavage at Tyr-|-Xaa bonds. High activity on hemoglobin.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei91 – 911
Active sitei276 – 2761

GO - Molecular functioni

  1. aspartic-type endopeptidase activity Source: ProtInc

GO - Biological processi

  1. digestion Source: ProtInc
  2. proteolysis Source: ProtInc
Complete GO annotation...

Keywords - Molecular functioni

Aspartyl protease, Hydrolase, Protease

Keywords - Biological processi

Digestion

Protein family/group databases

MEROPSiA01.003.

Names & Taxonomyi

Protein namesi
Recommended name:
Gastricsin (EC:3.4.23.3)
Alternative name(s):
Pepsinogen C
Gene namesi
Name:PGC
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome 6

Organism-specific databases

HGNCiHGNC:8890. PGC.

Subcellular locationi

GO - Cellular componenti

  1. extracellular space Source: ProtInc
  2. extracellular vesicular exosome Source: UniProt
Complete GO annotation...

Keywords - Cellular componenti

Secreted

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA33228.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 16162 PublicationsAdd
BLAST
Propeptidei17 – 5943Activation peptidePRO_0000026056Add
BLAST
Chaini60 – 388329GastricsinPRO_0000026057Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Disulfide bondi104 ↔ 109
Disulfide bondi267 ↔ 271
Disulfide bondi310 ↔ 343

Keywords - PTMi

Disulfide bond, Zymogen

Proteomic databases

MaxQBiP20142.
PaxDbiP20142.
PRIDEiP20142.

PTM databases

PhosphoSiteiP20142.

Miscellaneous databases

PMAP-CutDBP20142.

Expressioni

Gene expression databases

BgeeiP20142.
CleanExiHS_PGC.
ExpressionAtlasiP20142. baseline and differential.
GenevestigatoriP20142.

Organism-specific databases

HPAiHPA031717.
HPA031718.

Interactioni

Protein-protein interaction databases

BioGridi111246. 4 interactions.
STRINGi9606.ENSP00000362116.

Structurei

Secondary structure

1
388
Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Beta strandi19 – 257Combined sources
Helixi29 – 357Combined sources
Helixi39 – 435Combined sources
Helixi50 – 545Combined sources
Helixi65 – 684Combined sources
Beta strandi73 – 797Combined sources
Turni80 – 834Combined sources
Beta strandi84 – 918Combined sources
Beta strandi97 – 1015Combined sources
Helixi107 – 1104Combined sources
Helixi117 – 1193Combined sources
Beta strandi124 – 13411Combined sources
Beta strandi137 – 15014Combined sources
Beta strandi153 – 16513Combined sources
Helixi169 – 1735Combined sources
Beta strandi178 – 1814Combined sources
Helixi185 – 1873Combined sources
Helixi189 – 1913Combined sources
Helixi195 – 2017Combined sources
Beta strandi205 – 21410Combined sources
Beta strandi219 – 22911Combined sources
Helixi232 – 2343Combined sources
Beta strandi235 – 24410Combined sources
Beta strandi246 – 2494Combined sources
Beta strandi251 – 2544Combined sources
Beta strandi256 – 2594Combined sources
Turni266 – 2694Combined sources
Beta strandi271 – 2755Combined sources
Beta strandi281 – 2855Combined sources
Helixi286 – 2883Combined sources
Helixi289 – 2968Combined sources
Beta strandi306 – 3083Combined sources
Helixi310 – 3156Combined sources
Beta strandi319 – 3235Combined sources
Beta strandi326 – 3305Combined sources
Helixi332 – 3354Combined sources
Beta strandi336 – 3383Combined sources
Beta strandi343 – 3508Combined sources
Beta strandi360 – 3634Combined sources
Helixi365 – 3684Combined sources
Beta strandi371 – 3766Combined sources
Turni377 – 3804Combined sources
Beta strandi381 – 3877Combined sources

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1AVFX-ray2.36A/J60-388[»]
P/Q17-42[»]
1HTRX-ray1.62B60-388[»]
P17-59[»]
ProteinModelPortaliP20142.
SMRiP20142. Positions 17-388.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP20142.

Family & Domainsi

Sequence similaritiesi

Belongs to the peptidase A1 family.Curated

Keywords - Domaini

Signal

Phylogenomic databases

eggNOGiNOG248684.
GeneTreeiENSGT00760000118929.
HOGENOMiHOG000197681.
HOVERGENiHBG000482.
InParanoidiP20142.
KOiK01377.
OMAiASGWCSE.
OrthoDBiEOG7HQN88.
PhylomeDBiP20142.
TreeFamiTF314990.

Family and domain databases

Gene3Di2.40.70.10. 2 hits.
InterProiIPR001461. Aspartic_peptidase.
IPR001969. Aspartic_peptidase_AS.
IPR012848. Aspartic_peptidase_N.
IPR021109. Peptidase_aspartic_dom.
[Graphical view]
PANTHERiPTHR13683. PTHR13683. 1 hit.
PfamiPF07966. A1_Propeptide. 1 hit.
PF00026. Asp. 1 hit.
[Graphical view]
PRINTSiPR00792. PEPSIN.
SUPFAMiSSF50630. SSF50630. 1 hit.
PROSITEiPS00141. ASP_PROTEASE. 2 hits.
[Graphical view]

Sequences (2)i

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

This entry describes 2 isoformsi produced by alternative splicing. Align

Isoform 1 (identifier: P20142-1) [UniParc]FASTAAdd to Basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MKWMVVVLVC LQLLEAAVVK VPLKKFKSIR ETMKEKGLLG EFLRTHKYDP
60 70 80 90 100
AWKYRFGDLS VTYEPMAYMD AAYFGEISIG TPPQNFLVLF DTGSSNLWVP
110 120 130 140 150
SVYCQSQACT SHSRFNPSES STYSTNGQTF SLQYGSGSLT GFFGYDTLTV
160 170 180 190 200
QSIQVPNQEF GLSENEPGTN FVYAQFDGIM GLAYPALSVD EATTAMQGMV
210 220 230 240 250
QEGALTSPVF SVYLSNQQGS SGGAVVFGGV DSSLYTGQIY WAPVTQELYW
260 270 280 290 300
QIGIEEFLIG GQASGWCSEG CQAIVDTGTS LLTVPQQYMS ALLQATGAQE
310 320 330 340 350
DEYGQFLVNC NSIQNLPSLT FIINGVEFPL PPSSYILSNN GYCTVGVEPT
360 370 380
YLSSQNGQPL WILGDVFLRS YYSVYDLGNN RVGFATAA
Length:388
Mass (Da):42,426
Last modified:February 1, 1991 - v1
Checksum:iF862DFDC1438BB92
GO
Isoform 2 (identifier: P20142-2) [UniParc]FASTAAdd to Basket

The sequence of this isoform differs from the canonical sequence as follows:
     217-388: QQGSSGGAVV...NNRVGFATAA → LVLESSGLGP...PPRSQHHSGA

Show »
Length:315
Mass (Da):34,208
Checksum:i79BD7C79ABDF8879
GO

Sequence cautioni

The sequence AAA60062.1 differs from that shown. Reason: Erroneous initiation. Curated

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti40 – 412GE → ED AA sequence (PubMed:6816595)Curated
Sequence conflicti52 – 521W → S AA sequence (PubMed:6816595)Curated

Alternative sequence

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Alternative sequencei217 – 388172QQGSS…FATAA → LVLESSGLGPLLTPSRAAPP SSTLQLPEKPLEQTWNILTP FTKTLPVSNLSRKVTSWAGV GIPVTCLPEAGSGGERRAEC GLGVPTTRGPPRSQHHSGA in isoform 2. 1 PublicationVSP_042312Add
BLAST

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M18667
, M18659, M18660, M18661, M18662, M18663, M18664, M18665, M18666 Genomic DNA. Translation: AAA60062.1. Different initiation.
J04443 mRNA. Translation: AAA60074.1.
M23077
, M23069, M23070, M23071, M23072, M23073, M23074, M23075 Genomic DNA. Translation: AAA60063.1.
U75272 mRNA. Translation: AAB18273.1.
AK301298 mRNA. Translation: BAG62855.1.
AL365205 Genomic DNA. Translation: CAI13181.1.
BC073740 mRNA. Translation: AAH73740.1.
CCDSiCCDS4859.1. [P20142-1]
CCDS55000.1. [P20142-2]
PIRiA29937.
RefSeqiNP_001159896.1. NM_001166424.1. [P20142-2]
NP_002621.1. NM_002630.3. [P20142-1]
UniGeneiHs.1867.

Genome annotation databases

EnsembliENST00000373025; ENSP00000362116; ENSG00000096088. [P20142-1]
ENST00000425343; ENSP00000405094; ENSG00000096088. [P20142-2]
GeneIDi5225.
KEGGihsa:5225.
UCSCiuc003ora.2. human. [P20142-1]
uc021yzm.1. human. [P20142-2]

Polymorphism databases

DMDMi129796.

Keywords - Coding sequence diversityi

Alternative splicing

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M18667
, M18659 , M18660 , M18661 , M18662 , M18663 , M18664 , M18665 , M18666 Genomic DNA. Translation: AAA60062.1 . Different initiation.
J04443 mRNA. Translation: AAA60074.1 .
M23077
, M23069 , M23070 , M23071 , M23072 , M23073 , M23074 , M23075 Genomic DNA. Translation: AAA60063.1 .
U75272 mRNA. Translation: AAB18273.1 .
AK301298 mRNA. Translation: BAG62855.1 .
AL365205 Genomic DNA. Translation: CAI13181.1 .
BC073740 mRNA. Translation: AAH73740.1 .
CCDSi CCDS4859.1. [P20142-1 ]
CCDS55000.1. [P20142-2 ]
PIRi A29937.
RefSeqi NP_001159896.1. NM_001166424.1. [P20142-2 ]
NP_002621.1. NM_002630.3. [P20142-1 ]
UniGenei Hs.1867.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
Entry Method Resolution (Å) Chain Positions PDBsum
1AVF X-ray 2.36 A/J 60-388 [» ]
P/Q 17-42 [» ]
1HTR X-ray 1.62 B 60-388 [» ]
P 17-59 [» ]
ProteinModelPortali P20142.
SMRi P20142. Positions 17-388.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

BioGridi 111246. 4 interactions.
STRINGi 9606.ENSP00000362116.

Chemistry

BindingDBi P20142.
ChEMBLi CHEMBL2136.

Protein family/group databases

MEROPSi A01.003.

PTM databases

PhosphoSitei P20142.

Polymorphism databases

DMDMi 129796.

Proteomic databases

MaxQBi P20142.
PaxDbi P20142.
PRIDEi P20142.

Protocols and materials databases

DNASUi 5225.
Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENST00000373025 ; ENSP00000362116 ; ENSG00000096088 . [P20142-1 ]
ENST00000425343 ; ENSP00000405094 ; ENSG00000096088 . [P20142-2 ]
GeneIDi 5225.
KEGGi hsa:5225.
UCSCi uc003ora.2. human. [P20142-1 ]
uc021yzm.1. human. [P20142-2 ]

Organism-specific databases

CTDi 5225.
GeneCardsi GC06M041704.
HGNCi HGNC:8890. PGC.
HPAi HPA031717.
HPA031718.
MIMi 169740. gene.
neXtProti NX_P20142.
PharmGKBi PA33228.
GenAtlasi Search...

Phylogenomic databases

eggNOGi NOG248684.
GeneTreei ENSGT00760000118929.
HOGENOMi HOG000197681.
HOVERGENi HBG000482.
InParanoidi P20142.
KOi K01377.
OMAi ASGWCSE.
OrthoDBi EOG7HQN88.
PhylomeDBi P20142.
TreeFami TF314990.

Miscellaneous databases

ChiTaRSi PGC. human.
EvolutionaryTracei P20142.
GeneWikii Gastricsin.
GenomeRNAii 5225.
NextBioi 20200.
PMAP-CutDB P20142.
PROi P20142.
SOURCEi Search...

Gene expression databases

Bgeei P20142.
CleanExi HS_PGC.
ExpressionAtlasi P20142. baseline and differential.
Genevestigatori P20142.

Family and domain databases

Gene3Di 2.40.70.10. 2 hits.
InterProi IPR001461. Aspartic_peptidase.
IPR001969. Aspartic_peptidase_AS.
IPR012848. Aspartic_peptidase_N.
IPR021109. Peptidase_aspartic_dom.
[Graphical view ]
PANTHERi PTHR13683. PTHR13683. 1 hit.
Pfami PF07966. A1_Propeptide. 1 hit.
PF00026. Asp. 1 hit.
[Graphical view ]
PRINTSi PR00792. PEPSIN.
SUPFAMi SSF50630. SSF50630. 1 hit.
PROSITEi PS00141. ASP_PROTEASE. 2 hits.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Primary structure of human pepsinogen C gene."
    Hayano T., Sogawa K., Ichihara Y., Fujii-Kuriyama Y., Takahashi K.
    J. Biol. Chem. 263:1382-1385(1988) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
  2. Erratum
    Hayano T., Sogawa K., Ichihara Y., Fujii-Kuriyama Y., Takahashi K.
    J. Biol. Chem. 263:14592-14592(1988)
  3. "Human pepsinogen C (progastricsin). Isolation of cDNA clones, localization to chromosome 6, and sequence homology with pepsinogen A."
    Taggart R.T., Cass L.G., Mohandas T.K., Derby P., Barr P.J., Pals G., Bell G.I.
    J. Biol. Chem. 264:375-379(1989) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1).
  4. "Human pepsinogen C (progastricsin) polymorphism: evidence for a single locus located at 6p21.1-pter."
    Pals G., Azuma T., Mohandas T.K., Bell G.I., Bacon J., Samloff I.M., Walz D.A., Barr P.J., Taggart R.T.
    Genomics 4:137-148(1989) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Tissue: Placenta.
  5. "cDNA sequence of human gastricsin."
    Wong R.N.S., Tang J.
    Submitted (NOV-1996) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1).
  6. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
    Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
    , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
    Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2).
    Tissue: Stomach.
  7. "The DNA sequence and analysis of human chromosome 6."
    Mungall A.J., Palmer S.A., Sims S.K., Edwards C.A., Ashurst J.L., Wilming L., Jones M.C., Horton R., Hunt S.E., Scott C.E., Gilbert J.G.R., Clamp M.E., Bethel G., Milne S., Ainscough R., Almeida J.P., Ambrose K.D., Andrews T.D.
    , Ashwell R.I.S., Babbage A.K., Bagguley C.L., Bailey J., Banerjee R., Barker D.J., Barlow K.F., Bates K., Beare D.M., Beasley H., Beasley O., Bird C.P., Blakey S.E., Bray-Allen S., Brook J., Brown A.J., Brown J.Y., Burford D.C., Burrill W., Burton J., Carder C., Carter N.P., Chapman J.C., Clark S.Y., Clark G., Clee C.M., Clegg S., Cobley V., Collier R.E., Collins J.E., Colman L.K., Corby N.R., Coville G.J., Culley K.M., Dhami P., Davies J., Dunn M., Earthrowl M.E., Ellington A.E., Evans K.A., Faulkner L., Francis M.D., Frankish A., Frankland J., French L., Garner P., Garnett J., Ghori M.J., Gilby L.M., Gillson C.J., Glithero R.J., Grafham D.V., Grant M., Gribble S., Griffiths C., Griffiths M.N.D., Hall R., Halls K.S., Hammond S., Harley J.L., Hart E.A., Heath P.D., Heathcott R., Holmes S.J., Howden P.J., Howe K.L., Howell G.R., Huckle E., Humphray S.J., Humphries M.D., Hunt A.R., Johnson C.M., Joy A.A., Kay M., Keenan S.J., Kimberley A.M., King A., Laird G.K., Langford C., Lawlor S., Leongamornlert D.A., Leversha M., Lloyd C.R., Lloyd D.M., Loveland J.E., Lovell J., Martin S., Mashreghi-Mohammadi M., Maslen G.L., Matthews L., McCann O.T., McLaren S.J., McLay K., McMurray A., Moore M.J.F., Mullikin J.C., Niblett D., Nickerson T., Novik K.L., Oliver K., Overton-Larty E.K., Parker A., Patel R., Pearce A.V., Peck A.I., Phillimore B.J.C.T., Phillips S., Plumb R.W., Porter K.M., Ramsey Y., Ranby S.A., Rice C.M., Ross M.T., Searle S.M., Sehra H.K., Sheridan E., Skuce C.D., Smith S., Smith M., Spraggon L., Squares S.L., Steward C.A., Sycamore N., Tamlyn-Hall G., Tester J., Theaker A.J., Thomas D.W., Thorpe A., Tracey A., Tromans A., Tubby B., Wall M., Wallis J.M., West A.P., White S.S., Whitehead S.L., Whittaker H., Wild A., Willey D.J., Wilmer T.E., Wood J.M., Wray P.W., Wyatt J.C., Young L., Younger R.M., Bentley D.R., Coulson A., Durbin R.M., Hubbard T., Sulston J.E., Dunham I., Rogers J., Beck S.
    Nature 425:805-811(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  8. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
    Tissue: Liver.
  9. "A comparative study on the NH2-terminal amino acid sequences and some other properties of six isozymic forms of human pepsinogens and pepsins."
    Athauda S.B.P., Tanji M., Kageyama T., Takahashi K.
    J. Biochem. 106:920-927(1989) [PubMed] [Europe PMC] [Abstract]
    Cited for: PROTEIN SEQUENCE OF 17-101.
  10. "Human progastricsin. Analysis of intermediates during activation into gastricsin and determination of the amino acid sequence of the propart."
    Foltmann B., Jensen A.L.
    Eur. J. Biochem. 128:63-70(1982) [PubMed] [Europe PMC] [Abstract]
    Cited for: PROTEIN SEQUENCE OF 17-64.
  11. "Crystal and molecular structures of human progastricsin at 1.62-A resolution."
    Moore S.A., Sielecki A.R., Chernaia M.M., Tarasova N.I., James M.N.G.
    J. Mol. Biol. 247:466-485(1995) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (1.62 ANGSTROMS).
  12. "Structural characterization of activation 'intermediate 2' on the pathway to human gastricsin."
    Khan A.R., Cherney M.M., Tarasova N.I., James M.N.
    Nat. Struct. Biol. 4:1010-1015(1997) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (2.36 ANGSTROMS).

Entry informationi

Entry nameiPEPC_HUMAN
AccessioniPrimary (citable) accession number: P20142
Secondary accession number(s): B4DVZ3, Q5T3D7, Q5T3D8
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 1, 1991
Last sequence update: February 1, 1991
Last modified: November 26, 2014
This is version 149 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. Human chromosome 6
    Human chromosome 6: entries, gene names and cross-references to MIM
  2. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  3. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  4. Peptidase families
    Classification of peptidase families and list of entries
  5. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3