ID   GST5_CHICK              Reviewed;          28 AA.
AC   P20137;
DT   01-FEB-1991, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1991, sequence version 1.
DT   16-JUN-2009, entry version 53.
DE   RecName: Full=Glutathione S-transferase 5;
DE            EC=2.5.1.18;
DE   AltName: Full=GST-CL5;
DE   AltName: Full=GST class-sigma;
DE   Flags: Fragment;
OS   Gallus gallus (Chicken).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves;
OC   Neognathae; Galliformes; Phasianidae; Phasianinae; Gallus.
OX   NCBI_TaxID=9031;
RN   [1]
RP   PROTEIN SEQUENCE.
RC   TISSUE=Liver;
RX   MEDLINE=90248419; PubMed=2337594; DOI=10.1021/bi00455a022;
RA   Chang L.-H., Chuang L.-F., Tsai C.-P., Tu C.-P.D., Tam M.F.;
RT   "Characterization of glutathione S-transferases from day-old chick
RT   livers.";
RL   Biochemistry 29:744-750(1990).
CC   -!- FUNCTION: Conjugation of reduced glutathione to a wide number of
CC       exogenous and endogenous hydrophobic electrophiles.
CC   -!- CATALYTIC ACTIVITY: RX + glutathione = HX + R-S-glutathione.
CC   -!- SUBUNIT: Homodimer.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm.
CC   -!- SIMILARITY: Belongs to the GST superfamily. Sigma family.
CC   -!- SIMILARITY: Contains 1 GST N-terminal domain.
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DR   IPI; IPI00578428; -.
DR   PIR; C33948; C33948.
DR   HSSP; O60760; 1IYH.
DR   Ensembl; ENSGALG00000010402; Gallus gallus.
DR   HOVERGEN; P20137; -.
DR   BRENDA; 2.5.1.18; 4.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0004364; F:glutathione transferase activity; IEA:EC.
DR   InterPro; IPR004045; Glutathione_S-Trfase_N.
DR   InterPro; IPR012335; Thioredoxin_fold.
DR   Gene3D; G3DSA:3.40.30.10; Thioredoxin_fold; 1.
DR   Pfam; PF02798; GST_N; 1.
DR   PROSITE; PS50404; GST_NTER; 1.
PE   1: Evidence at protein level;
KW   Cytoplasm; Direct protein sequencing; Transferase.
FT   CHAIN         1    >28       Glutathione S-transferase 5.
FT                                /FTId=PRO_0000185921.
FT   DOMAIN        1    >28       GST N-terminal.
FT   NON_TER      28     28
SQ   SEQUENCE   28 AA;  3389 MW;  DA51DC0ABD203B12 CRC64;
     PNYKLTYFNL RGRAEISRYL FAYAGIKY
//