P20016 (DHE2_THUTH) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names	Recommended name: NAD-specific glutamate dehydrogenase Short name=NAD-GDH EC=1.4.1.2
Organism	Thunnus thynnus (Atlantic bluefin tuna) (Scomber thynnus)
Taxonomic identifier	8237 [NCBI]
Taxonomic lineage	Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Actinopterygii › Neopterygii › Teleostei › Euteleostei › Neoteleostei › Acanthomorpha › Acanthopterygii › Percomorpha › Perciformes › Scombroidei › Scombridae › Thunnus

Protein attributes

Sequence length	16 AA.
Sequence status	Fragment.
Protein existence	Evidence at protein level

General annotation (Comments)

Catalytic activity	L-glutamate + H2O + NAD+ = 2-oxoglutarate + NH3 + NADH.
Sequence similarities	Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

Ontologies

Keywords
Ligand	NAD
Molecular function	Oxidoreductase
Technical term	Direct protein sequencing
Gene Ontology (GO)
Molecular function	glutamate dehydrogenase (NAD+) activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	‹1 – ›16	›16	NAD-specific glutamate dehydrogenase		PRO_0000182734
Sites
	Active site	12	1
Experimental info
	Non-terminal residue	1	1
	Non-terminal residue	16	1

Sequences

	Sequence		Length	Mass (Da)
	P20016 [UniParc]. Last modified February 1, 1991. Version 1. Checksum: FF299AA7C5F1062F	FASTA	16	1,518
	10 CAVVDVPFGG AKAGVK

References

[1]	"Purification, characteristics and sequence of a peptide containing an essential lysine residue." Veronese F.M., Bevilacqua R., Boccu E., Brown D.M. Biochim. Biophys. Acta 445:1-13(1976) [PubMed: 182270] [Abstract] Cited for: PROTEIN SEQUENCE. Tissue: Liver.
+	Additional computationally mapped references.

Cross-references

Sequence databases
PIR	A12729.
3D structure databases
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Family and domain databases
PROSITE	PS00074. GLFV_DEHYDROGENASE. Partial match. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

DHE2_THUTH

Accession

Primary (citable) accession number: P20016

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 1, 1991
Last sequence update:	February 1, 1991
Last modified:	October 19, 2011
This is version 52 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Chordata Protein Annotation Program