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Protein

Hydrogenase-1 operon protein HyaF

Gene

hyaF

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Not known. Could enhance the incorporation of nickel to the hydrogenase.

Keywords - Ligandi

Nickel

Enzyme and pathway databases

BioCyciEcoCyc:EG10473-MONOMER.
ECOL316407:JW0959-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Hydrogenase-1 operon protein HyaF
Gene namesi
Name:hyaF
Ordered Locus Names:b0977, JW0959
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG10473. hyaF.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 285285Hydrogenase-1 operon protein HyaFPRO_0000201421Add
BLAST

Proteomic databases

PaxDbiP19932.

Interactioni

Protein-protein interaction databases

BioGridi4260047. 17 interactions.
IntActiP19932. 9 interactions.
STRINGi511145.b0977.

Structurei

3D structure databases

ProteinModelPortaliP19932.
SMRiP19932. Positions 164-279.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the HupH/HyaF family.Curated

Phylogenomic databases

eggNOGiENOG4105MVP. Bacteria.
ENOG4111IMM. LUCA.
HOGENOMiHOG000118840.
InParanoidiP19932.
KOiK03618.
OMAiGYGSCRV.
PhylomeDBiP19932.

Family and domain databases

InterProiIPR006894. HupH_Hydgase_express_prot_C.
[Graphical view]
PfamiPF04809. HupH_C. 2 hits.
[Graphical view]
ProDomiPD005668. PD005668. 2 hits.
[Graphical view] [Entries sharing at least one domain]

Sequencei

Sequence statusi: Complete.

P19932-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSETFFHLLG PGTQPNDDSF SMNPLPITCQ VNDEPSMAAL EQCAHSPQVI
60 70 80 90 100
ALLNELQHQL SERQPPLGEV LAVDLLNLNA DDRHFINTLL GEGEVSVRIQ
110 120 130 140 150
QADDSESEIQ EAIFCGLWRV RRRRGEKLLE DKLEAGCAPL ALWQAATQNL
160 170 180 190 200
LPTDSLLPPP IDGLMNGLPL AHELLAHVRN PDAQPHSINL TQLPISEADR
210 220 230 240 250
LFLSRLCGPG NIQIRTIGYG ESYINATGLR HVWHLRCTDT LKGPLLESYE
260 270 280
ICPIPEVVLA APEDLVDSAQ RLSEVCQWLA EAAPT
Length:285
Mass (Da):31,431
Last modified:February 1, 1991 - v1
Checksum:iBD94FB06730C204A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M34825 Genomic DNA. Translation: AAA24002.1.
U00096 Genomic DNA. Translation: AAC74062.1.
AP009048 Genomic DNA. Translation: BAA35742.1.
PIRiJV0077. QQECHF.
RefSeqiNP_415496.1. NC_000913.3.
WP_000004899.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAC74062; AAC74062; b0977.
BAA35742; BAA35742; BAA35742.
GeneIDi945572.
KEGGiecj:JW0959.
eco:b0977.
PATRICi32117175. VBIEscCol129921_1011.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M34825 Genomic DNA. Translation: AAA24002.1.
U00096 Genomic DNA. Translation: AAC74062.1.
AP009048 Genomic DNA. Translation: BAA35742.1.
PIRiJV0077. QQECHF.
RefSeqiNP_415496.1. NC_000913.3.
WP_000004899.1. NZ_LN832404.1.

3D structure databases

ProteinModelPortaliP19932.
SMRiP19932. Positions 164-279.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4260047. 17 interactions.
IntActiP19932. 9 interactions.
STRINGi511145.b0977.

Proteomic databases

PaxDbiP19932.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC74062; AAC74062; b0977.
BAA35742; BAA35742; BAA35742.
GeneIDi945572.
KEGGiecj:JW0959.
eco:b0977.
PATRICi32117175. VBIEscCol129921_1011.

Organism-specific databases

EchoBASEiEB0468.
EcoGeneiEG10473. hyaF.

Phylogenomic databases

eggNOGiENOG4105MVP. Bacteria.
ENOG4111IMM. LUCA.
HOGENOMiHOG000118840.
InParanoidiP19932.
KOiK03618.
OMAiGYGSCRV.
PhylomeDBiP19932.

Enzyme and pathway databases

BioCyciEcoCyc:EG10473-MONOMER.
ECOL316407:JW0959-MONOMER.

Miscellaneous databases

PROiP19932.

Family and domain databases

InterProiIPR006894. HupH_Hydgase_express_prot_C.
[Graphical view]
PfamiPF04809. HupH_C. 2 hits.
[Graphical view]
ProDomiPD005668. PD005668. 2 hits.
[Graphical view] [Entries sharing at least one domain]
ProtoNetiSearch...

Entry informationi

Entry nameiHYAF_ECOLI
AccessioniPrimary (citable) accession number: P19932
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 1, 1991
Last sequence update: February 1, 1991
Last modified: September 7, 2016
This is version 102 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.