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Protein

Hydrogenase-1 operon protein HyaE

Gene

hyaE

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Not known. Could form, along with HyaD, a complex involved in the processing of the hydrogenase 1 structural operon.

GO - Molecular functioni

  • signal sequence binding Source: EcoCyc
Complete GO annotation...

Enzyme and pathway databases

BioCyciEcoCyc:EG10472-MONOMER.
ECOL316407:JW0958-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Hydrogenase-1 operon protein HyaE
Gene namesi
Name:hyaE
Ordered Locus Names:b0976, JW0958
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG10472. hyaE.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 132132Hydrogenase-1 operon protein HyaEPRO_0000201414Add
BLAST

Proteomic databases

PaxDbiP19931.
PRIDEiP19931.

Interactioni

Protein-protein interaction databases

BioGridi4260046. 17 interactions.
DIPiDIP-9961N.
IntActiP19931. 10 interactions.
STRINGi511145.b0976.

Structurei

Secondary structure

1
132
Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Helixi6 – 1510Combined sources
Turni16 – 183Combined sources
Beta strandi20 – 223Combined sources
Helixi24 – 3310Combined sources
Beta strandi35 – 417Combined sources
Beta strandi49 – 524Combined sources
Helixi56 – 627Combined sources
Beta strandi70 – 756Combined sources
Helixi77 – 8711Combined sources
Beta strandi94 – 996Combined sources
Beta strandi102 – 1076Combined sources
Helixi113 – 12412Combined sources

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
2HFDNMR-A1-132[»]
ProteinModelPortaliP19931.
SMRiP19931. Positions 1-132.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP19931.

Family & Domainsi

Sequence similaritiesi

Belongs to the HupG/HyaE family.Curated

Phylogenomic databases

eggNOGiENOG4108VXY. Bacteria.
ENOG4111JYZ. LUCA.
HOGENOMiHOG000118819.
InParanoidiP19931.
KOiK03619.
OMAiWHIAMAD.

Family and domain databases

Gene3Di3.40.30.10. 1 hit.
InterProiIPR010893. NiFe-hyd_mat_HyaE.
IPR012336. Thioredoxin-like_fold.
[Graphical view]
PfamiPF07449. HyaE. 1 hit.
[Graphical view]
SUPFAMiSSF52833. SSF52833. 1 hit.

Sequencei

Sequence statusi: Complete.

P19931-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSNDTPFDAL WQRMLARGWT PVSESRLDDW LTQAPDGVVL LSSDPKRTPE
60 70 80 90 100
VSDNPVMIGE LLREFPDYTW QVAIADLEQS EAIGDRFGVF RFPATLVFTG
110 120 130
GNYRGVLNGI HPWAELINLM RGLVEPQQER AS
Length:132
Mass (Da):14,890
Last modified:February 1, 1991 - v1
Checksum:iDA27A3A55C4A6B5A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M34825 Genomic DNA. Translation: AAA24001.1.
U00096 Genomic DNA. Translation: AAC74061.1.
AP009048 Genomic DNA. Translation: BAA35741.1.
PIRiJV0076. QQECHE.
RefSeqiNP_415495.1. NC_000913.3.
WP_000063978.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAC74061; AAC74061; b0976.
BAA35741; BAA35741; BAA35741.
GeneIDi945573.
KEGGiecj:JW0958.
eco:b0976.
PATRICi32117173. VBIEscCol129921_1010.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M34825 Genomic DNA. Translation: AAA24001.1.
U00096 Genomic DNA. Translation: AAC74061.1.
AP009048 Genomic DNA. Translation: BAA35741.1.
PIRiJV0076. QQECHE.
RefSeqiNP_415495.1. NC_000913.3.
WP_000063978.1. NZ_LN832404.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
2HFDNMR-A1-132[»]
ProteinModelPortaliP19931.
SMRiP19931. Positions 1-132.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4260046. 17 interactions.
DIPiDIP-9961N.
IntActiP19931. 10 interactions.
STRINGi511145.b0976.

Proteomic databases

PaxDbiP19931.
PRIDEiP19931.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC74061; AAC74061; b0976.
BAA35741; BAA35741; BAA35741.
GeneIDi945573.
KEGGiecj:JW0958.
eco:b0976.
PATRICi32117173. VBIEscCol129921_1010.

Organism-specific databases

EchoBASEiEB0467.
EcoGeneiEG10472. hyaE.

Phylogenomic databases

eggNOGiENOG4108VXY. Bacteria.
ENOG4111JYZ. LUCA.
HOGENOMiHOG000118819.
InParanoidiP19931.
KOiK03619.
OMAiWHIAMAD.

Enzyme and pathway databases

BioCyciEcoCyc:EG10472-MONOMER.
ECOL316407:JW0958-MONOMER.

Miscellaneous databases

EvolutionaryTraceiP19931.
PROiP19931.

Family and domain databases

Gene3Di3.40.30.10. 1 hit.
InterProiIPR010893. NiFe-hyd_mat_HyaE.
IPR012336. Thioredoxin-like_fold.
[Graphical view]
PfamiPF07449. HyaE. 1 hit.
[Graphical view]
SUPFAMiSSF52833. SSF52833. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiHYAE_ECOLI
AccessioniPrimary (citable) accession number: P19931
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 1, 1991
Last sequence update: February 1, 1991
Last modified: September 7, 2016
This is version 108 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  3. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.