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Protein

Hydrogenase-1 operon protein HyaE

Gene

hyaE

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Not known. Could form, along with HyaD, a complex involved in the processing of the hydrogenase 1 structural operon.

GO - Molecular functioni

  • signal sequence binding Source: EcoCyc

Enzyme and pathway databases

BioCyciEcoCyc:EG10472-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Hydrogenase-1 operon protein HyaE
Gene namesi
Name:hyaE
Ordered Locus Names:b0976, JW0958
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG10472 hyaE

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002014141 – 132Hydrogenase-1 operon protein HyaEAdd BLAST132

Proteomic databases

PaxDbiP19931
PRIDEiP19931

Interactioni

Protein-protein interaction databases

BioGridi4260046, 21 interactors
DIPiDIP-9961N
IntActiP19931, 10 interactors
STRINGi316385.ECDH10B_1046

Structurei

Secondary structure

1132
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Helixi6 – 15Combined sources10
Turni16 – 18Combined sources3
Beta strandi20 – 22Combined sources3
Helixi24 – 33Combined sources10
Beta strandi35 – 41Combined sources7
Beta strandi49 – 52Combined sources4
Helixi56 – 62Combined sources7
Beta strandi70 – 75Combined sources6
Helixi77 – 87Combined sources11
Beta strandi94 – 99Combined sources6
Beta strandi102 – 107Combined sources6
Helixi113 – 124Combined sources12

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
2HFDNMR-A1-132[»]
ProteinModelPortaliP19931
SMRiP19931
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP19931

Family & Domainsi

Sequence similaritiesi

Belongs to the HupG/HyaE family.Curated

Phylogenomic databases

eggNOGiENOG4108VXY Bacteria
ENOG4111JYZ LUCA
HOGENOMiHOG000118819
InParanoidiP19931
KOiK03619
OMAiWHIAMAD

Family and domain databases

CDDicd02965 HyaE, 1 hit
InterProiView protein in InterPro
IPR010893 NiFe-hyd_mat_HyaE
IPR036249 Thioredoxin-like_sf
PfamiView protein in Pfam
PF07449 HyaE, 1 hit
SUPFAMiSSF52833 SSF52833, 1 hit

Sequencei

Sequence statusi: Complete.

P19931-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSNDTPFDAL WQRMLARGWT PVSESRLDDW LTQAPDGVVL LSSDPKRTPE
60 70 80 90 100
VSDNPVMIGE LLREFPDYTW QVAIADLEQS EAIGDRFGVF RFPATLVFTG
110 120 130
GNYRGVLNGI HPWAELINLM RGLVEPQQER AS
Length:132
Mass (Da):14,890
Last modified:February 1, 1991 - v1
Checksum:iDA27A3A55C4A6B5A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M34825 Genomic DNA Translation: AAA24001.1
U00096 Genomic DNA Translation: AAC74061.1
AP009048 Genomic DNA Translation: BAA35741.1
PIRiJV0076 QQECHE
RefSeqiNP_415495.1, NC_000913.3
WP_000063978.1, NZ_LN832404.1

Genome annotation databases

EnsemblBacteriaiAAC74061; AAC74061; b0976
BAA35741; BAA35741; BAA35741
GeneIDi945573
KEGGiecj:JW0958
eco:b0976
PATRICifig|1411691.4.peg.1298

Entry informationi

Entry nameiHYAE_ECOLI
AccessioniPrimary (citable) accession number: P19931
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 1, 1991
Last sequence update: February 1, 1991
Last modified: March 28, 2018
This is version 118 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  3. SIMILARITY comments
    Index of protein domains and families

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