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Protein

Immunoglobulin G-binding protein G

Gene

spg

Organism
Streptococcus sp. group G
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

GO - Biological processi

Complete GO annotation...

Keywordsi

Molecular functionIgG-binding protein

Names & Taxonomyi

Protein namesi
Recommended name:
Immunoglobulin G-binding protein G
Short name:
IgG-binding protein G
Gene namesi
Name:spg
OrganismiStreptococcus sp. group G
Taxonomic identifieri1320 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesStreptococcaceaeStreptococcus

Subcellular locationi

  • Secretedcell wall PROSITE-ProRule annotation; Peptidoglycan-anchor PROSITE-ProRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cell wall, Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 33Add BLAST33
ChainiPRO_000000565934 – 562Immunoglobulin G-binding protein GAdd BLAST529
PropeptideiPRO_0000005660563 – 593Removed by sortasePROSITE-ProRule annotationAdd BLAST31

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei562Pentaglycyl murein peptidoglycan amidated threoninePROSITE-ProRule annotation1

Keywords - PTMi

Peptidoglycan-anchor

Proteomic databases

PRIDEiP19909.

Interactioni

Protein-protein interaction databases

MINTiMINT-1509283.

Structurei

Secondary structure

1593
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Helixi254 – 268Combined sources15
Helixi272 – 279Combined sources8
Helixi284 – 296Combined sources13
Beta strandi303 – 309Combined sources7
Beta strandi311 – 313Combined sources3
Beta strandi314 – 320Combined sources7
Helixi324 – 337Combined sources14
Beta strandi343 – 347Combined sources5
Helixi348 – 350Combined sources3
Beta strandi352 – 356Combined sources5
Beta strandi373 – 379Combined sources7
Beta strandi384 – 390Combined sources7
Beta strandi391 – 393Combined sources3
Helixi394 – 407Combined sources14
Beta strandi413 – 417Combined sources5
Turni418 – 421Combined sources4
Beta strandi422 – 426Combined sources5
Helixi431 – 440Combined sources10
Beta strandi444 – 449Combined sources6
Beta strandi454 – 460Combined sources7
Helixi464 – 477Combined sources14
Beta strandi483 – 487Combined sources5
Turni488 – 491Combined sources4
Beta strandi492 – 496Combined sources5

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1FCCX-ray3.20C/D372-427[»]
1FCLNMR-A372-427[»]
1FD6NMR-A372-427[»]
1GB4NMR-A372-427[»]
1GJSNMR-A254-299[»]
1GJTNMR-A254-299[»]
1IBXNMR-B-[»]
1P7ENMR-A444-497[»]
1P7FNMR-A444-497[»]
1QKZX-ray1.95A368-430[»]
1UWXX-ray2.20A/B368-430[»]
1ZXHNMR-A453-495[»]
2GI9X-ray1.14A303-357[»]
2I2YNMR-A304-357[»]
2I38NMR-A304-357[»]
2IGGNMR-A367-430[»]
2JSVNMR-X303-357[»]
2JU6NMR-X304-357[»]
2KHUNMR-A304-357[»]
2KHWNMR-A304-357[»]
2KN4NMR-A304-357[»]
2KQ4NMR-X303-357[»]
2KWDNMR-A/B/C/D/E304-357[»]
2LUMNMR-A444-497[»]
2OEDNMR-A444-497[»]
2ON8X-ray1.35A373-427[»]
2ONQX-ray1.70A375-427[»]
2QMTX-ray1.05A303-357[»]
3FILX-ray0.88A/B303-357[»]
3UI3X-ray2.80A/B304-357[»]
3V3XX-ray2.00A/B/C/D304-357[»]
4OZAX-ray2.20A302-357[»]
4OZBX-ray1.80A/B302-357[»]
4OZCX-ray2.30A302-357[»]
4WH4X-ray2.20A/B304-357[»]
5BMGX-ray2.20A/B/C/D/E/F/G/H304-357[»]
5BMHX-ray1.60A304-357[»]
5BMIX-ray2.50A304-357[»]
5HFYX-ray1.95A/B302-357[»]
5HG2X-ray1.80A/B/C/D302-357[»]
5HI1X-ray2.15A/B/C/D/E/F/G/H302-357[»]
ProteinModelPortaliP19909.
SMRiP19909.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP19909.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Repeati104 – 1401-1Add BLAST37
Repeati179 – 2151-2Add BLAST37
Repeati254 – 2901-3Add BLAST37
Repeati303 – 3572-1Add BLAST55
Repeati373 – 4272-2Add BLAST55

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni104 – 2903 X 37 AA repeatsAdd BLAST187
Regioni303 – 4272 X 55 AA repeatsAdd BLAST125
Regioni531 – 5555 X 5 AA repeats of [DE]-D-A-K-KAdd BLAST25

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi559 – 563LPXTG sorting signalPROSITE-ProRule annotation5

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi69 – 111Ala-richAdd BLAST43

Keywords - Domaini

Repeat, Signal

Family and domain databases

InterProiIPR019948. Gram-positive_anchor.
IPR009063. Ig/albumin-bd.
IPR000724. IgG-bd_B.
IPR019950. M_anchor.
IPR005877. YSIRK_signal_dom.
[Graphical view]
PfamiPF00746. Gram_pos_anchor. 1 hit.
PF01378. IgG_binding_B. 3 hits.
[Graphical view]
PRINTSiPR00015. GPOSANCHOR.
SUPFAMiSSF46997. SSF46997. 3 hits.
TIGRFAMsiTIGR01168. YSIRK_signal. 1 hit.
PROSITEiPS50847. GRAM_POS_ANCHORING. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P19909-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEKEKKVKYF LRKSAFGLAS VSAAFLVGST VFAVDSPIED TPIIRNGGEL
60 70 80 90 100
TNLLGNSETT LALRNEESAT ADLTAAAVAD TVAAAAAENA GAAAWEAAAA
110 120 130 140 150
ADALAKAKAD ALKEFNKYGV SDYYKNLINN AKTVEGVKDL QAQVVESAKK
160 170 180 190 200
ARISEATDGL SDFLKSQTPA EDTVKSIELA EAKVLANREL DKYGVSDYHK
210 220 230 240 250
NLINNAKTVE GVKDLQAQVV ESAKKARISE ATDGLSDFLK SQTPAEDTVK
260 270 280 290 300
SIELAEAKVL ANRELDKYGV SDYYKNLINN AKTVEGVKAL IDEILAALPK
310 320 330 340 350
TDTYKLILNG KTLKGETTTE AVDAATAEKV FKQYANDNGV DGEWTYDDAT
360 370 380 390 400
KTFTVTEKPE VIDASELTPA VTTYKLVING KTLKGETTTE AVDAATAEKV
410 420 430 440 450
FKQYANDNGV DGEWTYDDAT KTFTVTEKPE VIDASELTPA VTTYKLVING
460 470 480 490 500
KTLKGETTTK AVDAETAEKA FKQYANDNGV DGVWTYDDAT KTFTVTEMVT
510 520 530 540 550
EVPGDAPTEP EKPEASIPLV PLTPATPIAK DDAKKDDTKK EDAKKPEAKK
560 570 580 590
EDAKKAETLP TTGEGSNPFF TAAALAVMAG AGALAVASKR KED
Length:593
Mass (Da):63,292
Last modified:February 1, 1991 - v1
Checksum:i048BAA760D5B2920
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X06173 Genomic DNA. Translation: CAA29540.1.
Y00428 Genomic DNA. Translation: CAA68489.1.
X04015 Genomic DNA. Translation: CAA27638.1.
PIRiS00128.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X06173 Genomic DNA. Translation: CAA29540.1.
Y00428 Genomic DNA. Translation: CAA68489.1.
X04015 Genomic DNA. Translation: CAA27638.1.
PIRiS00128.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1FCCX-ray3.20C/D372-427[»]
1FCLNMR-A372-427[»]
1FD6NMR-A372-427[»]
1GB4NMR-A372-427[»]
1GJSNMR-A254-299[»]
1GJTNMR-A254-299[»]
1IBXNMR-B-[»]
1P7ENMR-A444-497[»]
1P7FNMR-A444-497[»]
1QKZX-ray1.95A368-430[»]
1UWXX-ray2.20A/B368-430[»]
1ZXHNMR-A453-495[»]
2GI9X-ray1.14A303-357[»]
2I2YNMR-A304-357[»]
2I38NMR-A304-357[»]
2IGGNMR-A367-430[»]
2JSVNMR-X303-357[»]
2JU6NMR-X304-357[»]
2KHUNMR-A304-357[»]
2KHWNMR-A304-357[»]
2KN4NMR-A304-357[»]
2KQ4NMR-X303-357[»]
2KWDNMR-A/B/C/D/E304-357[»]
2LUMNMR-A444-497[»]
2OEDNMR-A444-497[»]
2ON8X-ray1.35A373-427[»]
2ONQX-ray1.70A375-427[»]
2QMTX-ray1.05A303-357[»]
3FILX-ray0.88A/B303-357[»]
3UI3X-ray2.80A/B304-357[»]
3V3XX-ray2.00A/B/C/D304-357[»]
4OZAX-ray2.20A302-357[»]
4OZBX-ray1.80A/B302-357[»]
4OZCX-ray2.30A302-357[»]
4WH4X-ray2.20A/B304-357[»]
5BMGX-ray2.20A/B/C/D/E/F/G/H304-357[»]
5BMHX-ray1.60A304-357[»]
5BMIX-ray2.50A304-357[»]
5HFYX-ray1.95A/B302-357[»]
5HG2X-ray1.80A/B/C/D302-357[»]
5HI1X-ray2.15A/B/C/D/E/F/G/H302-357[»]
ProteinModelPortaliP19909.
SMRiP19909.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

MINTiMINT-1509283.

Proteomic databases

PRIDEiP19909.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Miscellaneous databases

EvolutionaryTraceiP19909.

Family and domain databases

InterProiIPR019948. Gram-positive_anchor.
IPR009063. Ig/albumin-bd.
IPR000724. IgG-bd_B.
IPR019950. M_anchor.
IPR005877. YSIRK_signal_dom.
[Graphical view]
PfamiPF00746. Gram_pos_anchor. 1 hit.
PF01378. IgG_binding_B. 3 hits.
[Graphical view]
PRINTSiPR00015. GPOSANCHOR.
SUPFAMiSSF46997. SSF46997. 3 hits.
TIGRFAMsiTIGR01168. YSIRK_signal. 1 hit.
PROSITEiPS50847. GRAM_POS_ANCHORING. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiSPG2_STRSG
AccessioniPrimary (citable) accession number: P19909
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 1, 1991
Last sequence update: February 1, 1991
Last modified: January 18, 2017
This is version 127 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.