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P19865

- CRG2_RHIAS

UniProt

P19865 - CRG2_RHIAS

Protein

Gamma-II crystallin

Gene
N/A
Organism
Rhizoprionodon acutus (Milk shark) (Scoliodon walbeemii)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at protein leveli
  1. Functioni

    Crystallins are the dominant structural components of the vertebrate eye lens.

    GO - Molecular functioni

    1. structural constituent of eye lens Source: UniProtKB-KW

    Keywords - Molecular functioni

    Eye lens protein

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Gamma-II crystallin
    OrganismiRhizoprionodon acutus (Milk shark) (Scoliodon walbeemii)
    Taxonomic identifieri34770 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataChondrichthyesElasmobranchiiGaleomorphiiGaleoideaCarcharhiniformesCarcharhinidaeRhizoprionodon

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – ›30›30Gamma-II crystallinPRO_0000057579Add
    BLAST

    Interactioni

    Subunit structurei

    Monomer.By similarity

    Structurei

    Secondary structure

    1
    30
    Legend: HelixTurnBeta strand
    Show more details
    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Beta strandi3 – 86
    Turni9 – 113
    Beta strandi12 – 209
    Turni26 – 283

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    EntryMethodResolution (Å)ChainPositionsPDBsum
    2GS1model-A1-30[»]
    ProteinModelPortaliP19865.
    SMRiP19865. Positions 1-30.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Region

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Regioni1 – ›30›30Beta/gamma crystallin 'Greek key'Add
    BLAST

    Domaini

    Has a two-domain beta-structure, folded into four very similar Greek key motifs.

    Sequence similaritiesi

    Belongs to the beta/gamma-crystallin family.Curated
    Contains at least 1 beta/gamma crystallin 'Greek key' domain.Curated

    Keywords - Domaini

    Repeat

    Family and domain databases

    InterProiIPR001064. Beta/gamma_crystallin.
    IPR011024. G_crystallin-rel.
    [Graphical view]
    PfamiPF00030. Crystall. 1 hit.
    [Graphical view]
    SUPFAMiSSF49695. SSF49695. 1 hit.
    PROSITEiPS50915. CRYSTALLIN_BETA_GAMMA. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Fragment.

    P19865-1 [UniParc]FASTAAdd to Basket

    « Hide

    GKITFYEDRN FQGRCYECST DCPDLSPYFS                         30
    Length:30
    Mass (Da):3,543
    Last modified:February 1, 1991 - v1
    Checksum:i229E65B93CD7F68E
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Non-terminal residuei30 – 301

    Cross-referencesi

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    Entry Method Resolution (Å) Chain Positions PDBsum
    2GS1 model - A 1-30 [» ]
    ProteinModelPortali P19865.
    SMRi P19865. Positions 1-30.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Family and domain databases

    InterProi IPR001064. Beta/gamma_crystallin.
    IPR011024. G_crystallin-rel.
    [Graphical view ]
    Pfami PF00030. Crystall. 1 hit.
    [Graphical view ]
    SUPFAMi SSF49695. SSF49695. 1 hit.
    PROSITEi PS50915. CRYSTALLIN_BETA_GAMMA. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Comparison of the gamma-crystallins isolated from eye lenses of shark and carp. Unique secondary and tertiary structure of shark gamma-crystallin."
      Chiou S.-H., Chen S.-W., Itoh T., Kaji H., Samejima T.
      FEBS Lett. 275:111-113(1990) [PubMed] [Europe PMC] [Abstract]
      Cited for: PROTEIN SEQUENCE.
      Tissue: Lens.

    Entry informationi

    Entry nameiCRG2_RHIAS
    AccessioniPrimary (citable) accession number: P19865
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: February 1, 1991
    Last sequence update: February 1, 1991
    Last modified: October 1, 2014
    This is version 65 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    3D-structure, Direct protein sequencing

    Documents

    1. PDB cross-references
      Index of Protein Data Bank (PDB) cross-references
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3