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P19865 (CRG2_RHIAS) Reviewed, UniProtKB/Swiss-Prot

Last modified January 22, 2014. Version 64. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein attributes

Sequence length30 AA.
Sequence statusFragment.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Crystallins are the dominant structural components of the vertebrate eye lens.

Subunit structure

Monomer By similarity.

Domain

Has a two-domain beta-structure, folded into four very similar Greek key motifs.

Sequence similarities

Belongs to the beta/gamma-crystallin family.

Contains at least 1 beta/gamma crystallin 'Greek key' domain.

Ontologies

Keywords
   DomainRepeat
   Molecular functionEye lens protein
   Technical term3D-structure
Direct protein sequencing
Gene Ontology (GO)
   Molecular_functionstructural constituent of eye lens

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – ›30›30Gamma-II crystallin
PRO_0000057579

Regions

Region1 – ›30›30Beta/gamma crystallin 'Greek key'

Experimental info

Non-terminal residue301

Secondary structure

....... 30
Helix Strand Turn

Details...

Sequences

Sequence LengthMass (Da)Tools
P19865 [UniParc].

Last modified February 1, 1991. Version 1.
Checksum: 229E65B93CD7F68E

FASTA303,543
        10         20         30 
GKITFYEDRN FQGRCYECST DCPDLSPYFS 

« Hide

References

[1]"Comparison of the gamma-crystallins isolated from eye lenses of shark and carp. Unique secondary and tertiary structure of shark gamma-crystallin."
Chiou S.-H., Chen S.-W., Itoh T., Kaji H., Samejima T.
FEBS Lett. 275:111-113(1990) [PubMed] [Europe PMC] [Abstract]
Cited for: PROTEIN SEQUENCE.
Tissue: Lens.

Cross-references

3D structure databases

PDBe
RCSB-PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
2GS1model-A1-30[»]
ProteinModelPortalP19865.
SMRP19865. Positions 1-30.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Family and domain databases

InterProIPR001064. Beta/gamma_crystallin.
IPR011024. G_crystallin-rel.
[Graphical view]
PfamPF00030. Crystall. 1 hit.
[Graphical view]
SUPFAMSSF49695. SSF49695. 1 hit.
PROSITEPS50915. CRYSTALLIN_BETA_GAMMA. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameCRG2_RHIAS
AccessionPrimary (citable) accession number: P19865
Entry history
Integrated into UniProtKB/Swiss-Prot: February 1, 1991
Last sequence update: February 1, 1991
Last modified: January 22, 2014
This is version 64 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PDB cross-references

Index of Protein Data Bank (PDB) cross-references