Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

P19840

- LUXB1_PHOLU

UniProt

P19840 - LUXB1_PHOLU

Protein

Alkanal monooxygenase beta chain

Gene

luxB

Organism
Photorhabdus luminescens (Xenorhabdus luminescens)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 73 (01 Oct 2014)
      Sequence version 1 (01 Feb 1991)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Light-emitting reaction in luminous bacteria. The specific role of the beta subunit is unknown, but it is absolutely required for bioluminescence activity.

    Catalytic activityi

    RCHO + reduced FMN + O2 = RCOOH + FMN + H2O + light.

    GO - Molecular functioni

    1. alkanal monooxygenase (FMN-linked) activity Source: UniProtKB-EC

    GO - Biological processi

    1. bioluminescence Source: UniProtKB-KW

    Keywords - Molecular functioni

    Monooxygenase, Oxidoreductase, Photoprotein

    Keywords - Biological processi

    Luminescence

    Keywords - Ligandi

    Flavoprotein, FMN

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Alkanal monooxygenase beta chain (EC:1.14.14.3)
    Alternative name(s):
    Bacterial luciferase beta chain
    Gene namesi
    Name:luxB
    OrganismiPhotorhabdus luminescens (Xenorhabdus luminescens)
    Taxonomic identifieri29488 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaePhotorhabdus

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 327327Alkanal monooxygenase beta chainPRO_0000220177Add
    BLAST

    Proteomic databases

    PRIDEiP19840.

    Interactioni

    Subunit structurei

    Heterodimer of an alpha and a beta chain.

    Structurei

    3D structure databases

    ProteinModelPortaliP19840.
    SMRiP19840. Positions 1-319.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Family and domain databases

    Gene3Di3.20.20.30. 1 hit.
    InterProiIPR018235. Bacterial_luciferase_CS.
    IPR011251. Luciferase-like_dom.
    IPR002103. Luciferase_bac.
    [Graphical view]
    PfamiPF00296. Bac_luciferase. 1 hit.
    [Graphical view]
    PRINTSiPR00089. LUCIFERASE.
    SUPFAMiSSF51679. SSF51679. 1 hit.
    PROSITEiPS00494. BACTERIAL_LUCIFERASE. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    P19840-1 [UniParc]FASTAAdd to Basket

    « Hide

    MKFGLFFLNF INSTTVQEQS IVRMQEITEY VDKLNFEQIL VYENHFSDNG    50
    VVGAPLTVSG FLLGLTEKIK IGSLNHIITT HHPVAIAEEA CLLDQLSEGR 100
    FILGFSDCEK KDEMHFFNRP VEYQQQLFEE CYEIINDALT TGYCNPDNDF 150
    YSFPKISVNP HAYTPGGPRK YVTATSHHIV EWAAKKGIPL IFKWDDSNDV 200
    RYEYAERYKA VADKYDVDLS EIDHQLMILV NYNEDSNKAK QETRAFISDY 250
    VLEMHPNENF ENKLEEIIAE NAVGNYTECI TAAKLAIEKC GAKSVLLSFE 300
    PMNDLMSQKN VINIVDDNIK KYHMEYT 327
    Length:327
    Mass (Da):37,595
    Last modified:February 1, 1991 - v1
    Checksum:i1905AF01658BE56E
    GO

    Natural variant

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Natural varianti85 – 851A → R in strain: Hm.

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    M57416 Genomic DNA. Translation: AAA27624.1.
    M90093 Genomic DNA. Translation: AAA27620.1.
    M55977 Genomic DNA. Translation: AAA27627.1.
    PIRiC35411.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    M57416 Genomic DNA. Translation: AAA27624.1 .
    M90093 Genomic DNA. Translation: AAA27620.1 .
    M55977 Genomic DNA. Translation: AAA27627.1 .
    PIRi C35411.

    3D structure databases

    ProteinModelPortali P19840.
    SMRi P19840. Positions 1-319.
    ModBasei Search...
    MobiDBi Search...

    Proteomic databases

    PRIDEi P19840.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Family and domain databases

    Gene3Di 3.20.20.30. 1 hit.
    InterProi IPR018235. Bacterial_luciferase_CS.
    IPR011251. Luciferase-like_dom.
    IPR002103. Luciferase_bac.
    [Graphical view ]
    Pfami PF00296. Bac_luciferase. 1 hit.
    [Graphical view ]
    PRINTSi PR00089. LUCIFERASE.
    SUPFAMi SSF51679. SSF51679. 1 hit.
    PROSITEi PS00494. BACTERIAL_LUCIFERASE. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Nucleotide sequence, expression, and properties of luciferase coded by lux genes from a terrestrial bacterium."
      Szittner R., Meighen E.
      J. Biol. Chem. 265:16581-16587(1990) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
      Strain: ATCC 29999 / Hb / DSM 3368 / NCIB 12670.
    2. "Multiple repetitive elements and organization of the lux operons of luminescent terrestrial bacteria."
      Meighen E.A., Szittner R.B.
      J. Bacteriol. 174:5371-5381(1992) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
      Strain: ATCC 29999 / Hb / DSM 3368 / NCIB 12670.
    3. "The nucleotide sequence of the luxA and luxB genes of Xenorhabdus luminescens HM and a comparison of the amino acid sequences of luciferases from four species of bioluminescent bacteria."
      Johnston T.C., Rucker E.B., Cochrum L., Hruska K.S., Vandegrift V.
      Biochem. Biophys. Res. Commun. 170:407-415(1990) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
      Strain: Hm.

    Entry informationi

    Entry nameiLUXB1_PHOLU
    AccessioniPrimary (citable) accession number: P19840
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: February 1, 1991
    Last sequence update: February 1, 1991
    Last modified: October 1, 2014
    This is version 73 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3