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Reviewed, UniProtKB/Swiss-Prot P19817 (RFAJ_SALTY)

Last modified July 13, 2010. Version 77. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents
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Names and originHide

Protein namesRecommended name:
Lipopolysaccharide 1,2-glucosyltransferase
EC=2.4.1.58
Gene names
Name:rfaJ
Synonyms:waaJ
Ordered Locus Names:STM3717
OrganismSalmonella typhimurium [Complete proteome] [HAMAP]
Taxonomic identifier90371 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Salmonella
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Protein attributesHide

Sequence length336 AA.
Sequence statusComplete.
Protein existenceInferred from homology.
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General annotation (Comments)Hide

Function

Adds the glucose(II) group on the galactose(I) group of LPS.

Catalytic activity

UDP-glucose + lipopolysaccharide = UDP + D-glucosyl-lipopolysaccharide.

Pathway

Bacterial outer membrane biogenesis; LPS core biosynthesis.

Sequence similarities

Belongs to the glycosyltransferase 8 family.

Sequence caution

The sequence CAA37842.1 differs from that shown. Reason: Frameshift at positions 42, 138, 235 and 264.

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Sequence annotation (Features)Hide

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 336336Lipopolysaccharide 1,2-glucosyltransferase
PRO_0000206067
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SequencesHide

Sequence LengthMass (Da)Tools
P19817-1 [UniParc].

Last modified December 15, 1998. Version 4.
Checksum: AAB23E412429E00B

FASTA33638,763
        10         20         30         40         50         60 
MDSFPEIEIA EYKVFDESNN NDDNVLNISY GVDENYLDGV GVSIASVVLN NNIPLAFHII 

        70         80         90        100        110        120 
CDSYSPCFVK YIERLAVQHH IKISLYLIKV ESLEVLPQTK VWSRAMYFRL FAFDYLSKKV 

       130        140        150        160        170        180 
NTLLYLDADV VCKGSLQDLL QLDLTEKIAA VVKDVDSIQN KVNERLSAFN LQGGYFNSGV 

       190        200        210        220        230        240 
VFVNLKLWKE NALTKKAFLL LAGKEADSFK YPDQDVLNIL LQDKVIFLPR PYNTIYTIKS 

       250        260        270        280        290        300 
ELKDKSHKKY SNIINDNTIL IHYTGATKPW HAWANYPSVI YYKNARLNSP WKDFPAKDAR 

       310        320        330 
TIVEFKKRYK HLLVQGHYFK GLLAGSAYLY RKLFHK

« Hide

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ReferencesHide

« Hide 'large scale' references
[1]"Nucleotide sequence of rfaI and rfaJ genes encoding lipopolysaccharide glycosyl transferases from Salmonella typhimurium."
Carstenius P., Flock J.-I., Lindberg A.
Nucleic Acids Res. 18:6128-6128(1990) [PubMed: 2235496] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: LT2.
[2]"The assembly system for the lipopolysaccharide R2 core-type of Escherichia coli is a hybrid of those found in Escherichia coli K-12 and Salmonella enterica. Structure and function of the R2 WaaK and WaaL homologs."
Heinrichs D.E., Monteiro M.A., Perry M.B., Whitfield C.
J. Biol. Chem. 273:8849-8859(1998) [PubMed: 9535865] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: LT2.
[3]"Complete genome sequence of Salmonella enterica serovar Typhimurium LT2."
McClelland M., Sanderson K.E., Spieth J., Clifton S.W., Latreille P., Courtney L., Porwollik S., Ali J., Dante M., Du F., Hou S., Layman D., Leonard S., Nguyen C., Scott K., Holmes A., Grewal N., Mulvaney E. expand/collapse author list , Ryan E., Sun H., Florea L., Miller W., Stoneking T., Nhan M., Waterston R., Wilson R.K.
Nature 413:852-856(2001) [PubMed: 11677609] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: LT2 / SGSC1412 / ATCC 700720.
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Cross-referencesHide

Sequence databases

EMBL
GenBank
DDBJ		X53847 Genomic DNA. Translation: CAA37842.1. Frameshift.
AF026386 Genomic DNA. Translation: AAC16411.1.
AE006468 Genomic DNA. Translation: AAL22576.1.
PIRS12098.
RefSeqNP_462617.1.

3D structure databases

SMRP19817. Positions 26-279.
ModBaseSearch...

Protein family/group databases

CAZyGT8. Glycosyltransferase Family 8.

Proteomic databases

PRIDEP19817.

Genome annotation databases

GeneID1255241.
GenomeReviewsGene locus STM3717 in contig AE006468_GR.
KEGGstm:STM3717.
NMPDRfig|99287.1.peg.3593.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG417202.
OMADRSHRKF.
ProtClustDBCLSK2484803.

Enzyme and pathway databases

BioCycSTYP99287:STM3717-MONOMER.
BRENDA2.4.1.58. 2.

Family and domain databases

InterProIPR002495. Glyco_trans_8.
IPR013645. Glyco_transf_8N.
[Graphical view]
PfamPF01501. Glyco_transf_8. 1 hit.
PF08437. Glyco_transf_8N. 1 hit.
[Graphical view]
ProtoNetSearch...
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Entry informationHide

Entry nameRFAJ_SALTY
AccessionPrimary (citable) accession number: P19817
Secondary accession number(s): O68266
Entry history
Integrated into UniProtKB/Swiss-Prot: February 1, 1991
Last sequence update: December 15, 1998
Last modified: July 13, 2010
This is version 77 of the entry and version 4 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectHAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)
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Relevant documentsHide

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents