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Protein

Putative transposase InsK for insertion sequence element IS150

Gene

insK

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Involved in the transposition of the insertion sequence IS150.

GO - Molecular functioni

GO - Biological processi

  • cellular response to DNA damage stimulus Source: EcoliWiki
  • DNA integration Source: InterPro
  • DNA recombination Source: UniProtKB-KW
  • transposition Source: UniProtKB-KW

Keywordsi

Molecular functionDNA-binding
Biological processDNA recombination, Transposition

Enzyme and pathway databases

BioCyciEcoCyc:G7777-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Putative transposase InsK for insertion sequence element IS150
Gene namesi
Name:insK
Ordered Locus Names:b3558, JW3528
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG40011 insK

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000754191 – 283Putative transposase InsK for insertion sequence element IS150Add BLAST283

Proteomic databases

PaxDbiP19769
PRIDEiP19769

Interactioni

Protein-protein interaction databases

IntActiP19769, 3 interactors
STRINGi316385.ECDH10B_3738

Structurei

3D structure databases

ProteinModelPortaliP19769
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini117 – 279Integrase catalyticPROSITE-ProRule annotationAdd BLAST163

Sequence similaritiesi

Belongs to the transposase IS3/IS150/IS904 family.Curated

Phylogenomic databases

eggNOGiENOG4105DQ6 Bacteria
COG2801 LUCA
HOGENOMiHOG000023133
InParanoidiP19769
KOiK07497
OMAiYETIMTP
PhylomeDBiP19769

Family and domain databases

Gene3Di3.30.420.10, 1 hit
InterProiView protein in InterPro
IPR025948 HTH-like_dom
IPR038965 InsF-like
IPR001584 Integrase_cat-core
IPR012337 RNaseH-like_sf
IPR036397 RNaseH_sf
PANTHERiPTHR42648 PTHR42648, 1 hit
PfamiView protein in Pfam
PF13276 HTH_21, 1 hit
PF00665 rve, 1 hit
SUPFAMiSSF53098 SSF53098, 1 hit
PROSITEiView protein in PROSITE
PS50994 INTEGRASE, 1 hit

Sequencei

Sequence statusi: Complete.

P19769-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKVLNELRQF YPLDELLRAA EIPRSTFYYH LKALSKPDKY ADVKKRISEI
60 70 80 90 100
YHENRGRYGY RRVTLSLHRE GKQINHKAVQ RLMGTLSLKA AIKVKRYRSY
110 120 130 140 150
RGEVGQTAPN VLQRDFKATR PNEKWVTDVT EFAVNGRKLY LSPVIDLFNN
160 170 180 190 200
EVISYSLSER PVMNMVENML DQAFKKLNPH EHPVLHSDQG WQYRMRRYQN
210 220 230 240 250
ILKEHGIKQS MSRKGNCLDN AVVECFFGTL KSECFYLDEF SNISELKDAV
260 270 280
TEYIEYYNSR RISLKLKGLT PIEYRNQTYM PRV
Length:283
Mass (Da):33,477
Last modified:June 27, 2006 - v2
Checksum:i3EA86375D52C42CB
GO

Sequence cautioni

The sequence AAB18535 differs from that shown. B-168 has been translated as Asn.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti213R → A in CAA30086 (PubMed:2841644).Curated1
Sequence conflicti213R → E no nucleotide entry (PubMed:2541046).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X07037 Genomic DNA Translation: CAA30086.1
U00039 Genomic DNA Translation: AAB18535.2 Sequence problems.
U00096 Genomic DNA Translation: AAC76582.1
AP009048 Genomic DNA Translation: BAE77736.1
RefSeqiNP_418015.1, NC_000913.3

Genome annotation databases

EnsemblBacteriaiAAC76582; AAC76582; b3558
BAE77736; BAE77736; BAE77736
GeneIDi948081
KEGGiecj:JW3528
eco:b3558
PATRICifig|511145.12.peg.3672

Similar proteinsi

Entry informationi

Entry nameiINSK_ECOLI
AccessioniPrimary (citable) accession number: P19769
Secondary accession number(s): Q2M7M0
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 1, 1991
Last sequence update: June 27, 2006
Last modified: May 23, 2018
This is version 116 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome, Transposable element

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families

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