P19733 (DMPO_PSEUF) Reviewed, UniProtKB/Swiss-Prot
Last modified
June 28, 2011.
Version 51.
History...
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize orderNames and origin
| Protein names | Recommended name: Phenol hydroxylase P4 protein EC=1.14.13.7 Alternative name(s): Phenol 2-monooxygenase P4 component | ||||
| Gene names |
| ||||
| Encoded on | Plasmid pVI150 | ||||
| Organism | Pseudomonas sp. (strain CF600) | ||||
| Taxonomic identifier | 79676 [NCBI] | ||||
| Taxonomic lineage | Bacteria › Proteobacteria |
Protein attributes
| Sequence length | 119 AA. |
| Sequence status | Complete. |
| Protein existence | Predicted |
General annotation (Comments)
| Function | Catabolizes phenol, and some of its methylated derivatives. P4 is required for growth on phenol, and for in vitro phenol hydroxylase activity. |
| Catalytic activity | Phenol + NADPH + O2 = catechol + NADP+ + H2O. |
| Cofactor | FAD. Fe2+. |
| Pathway | |
| Subunit structure | The multicomponent enzyme phenol hydroxylase is formed by P0, P1, P2, P3, P4 and P5 polypeptides. |
Ontologies
| Keywords | |
|---|---|
| Biological process | Aromatic hydrocarbons catabolism |
| Ligand | FAD Flavoprotein Iron NADP |
| Molecular function | Monooxygenase Oxidoreductase |
| Technical term | Plasmid |
| Gene Ontology (GO) | |
| Biological process | aromatic compound catabolic process Inferred from electronic annotation. Source: UniProtKB-KW |
| Molecular function | phenol 2-monooxygenase activity Inferred from electronic annotation. Source: EC |
| Complete GO annotation... | |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||
Molecule processing | |||||||
|---|---|---|---|---|---|---|---|
| Chain | 1 – 119 | 119 | Phenol hydroxylase P4 protein | PRO_0000079946 | |||
Sequences
References
| [1] | "Complete nucleotide sequence and polypeptide analysis of multicomponent phenol hydroxylase from Pseudomonas sp. strain CF600." Nordlund I., Powlowski J., Shingler V. J. Bacteriol. 172:6826-6833(1990) [PubMed: 2254258] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. |
| [2] | Takeo M., Maeda Y., Okada H., Miyama K., Mori K., Ike M., Fujita M. Submitted (MAR-1994) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: BH. |
Cross-references
Sequence databases | |
|---|---|
| EMBL GenBank DDBJ | M60276 Genomic DNA. Translation: AAA25943.1. D28864 Genomic DNA. Translation: BAA06018.1. |
3D structure databases | |
| ProteinModelPortal | P19733. |
| SMR | P19733. Positions 2-118. |
| ModBase | Search... |
Protocols and materials databases | |
| StructuralBiologyKnowledgebase | Search... |
Enzyme and pathway databases | |
| BioCyc | MetaCyc:MONOMER-12798. |
Family and domain databases | |
| InterPro | IPR006756. Phenol_hydroxylase. [Graphical view] |
| Pfam | PF04663. Phenol_monoox. 1 hit. [Graphical view] |
| ProtoNet | Search... |
Entry information
| Entry name | DMPO_PSEUF | ||||||||
| Accession | Primary (citable) accession number: P19733 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation program | Prokaryotic Protein Annotation Program | ||||||||
Relevant documents
| PATHWAY comments Index of metabolic and biosynthesis pathways |

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