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P19732

- DMPN_PSEUF

UniProt

P19732 - DMPN_PSEUF

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Protein

Phenol hydroxylase P3 protein

Gene

dmpN

Organism
Pseudomonas sp. (strain CF600)
Status
Reviewed - Annotation score: 3 out of 5- Protein predictedi

Functioni

Catabolizes phenol, and some of its methylated derivatives. P3 is required for growth on phenol, and for in vitro phenol hydroxylase activity.

Catalytic activityi

Phenol + NADPH + O2 = catechol + NADP+ + H2O.

Cofactori

FAD.
Fe2+.

Pathwayi

GO - Molecular functioni

  1. phenol 2-monooxygenase activity Source: UniProtKB-EC

GO - Biological processi

  1. phenol-containing compound catabolic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

Monooxygenase, Oxidoreductase

Keywords - Biological processi

Aromatic hydrocarbons catabolism

Keywords - Ligandi

FAD, Flavoprotein, Iron, NADP

Enzyme and pathway databases

BioCyciMetaCyc:MONOMER-12797.
UniPathwayiUPA00728.

Names & Taxonomyi

Protein namesi
Recommended name:
Phenol hydroxylase P3 protein (EC:1.14.13.7)
Alternative name(s):
Phenol 2-monooxygenase P3 component
Gene namesi
Name:dmpN
Synonyms:pheA4
Encoded oniPlasmid pVI1500 Publication
OrganismiPseudomonas sp. (strain CF600)
Taxonomic identifieri79676 [NCBI]
Taxonomic lineageiBacteriaProteobacteria

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 517517Phenol hydroxylase P3 proteinPRO_0000079945Add
BLAST

Interactioni

Subunit structurei

The multicomponent enzyme phenol hydroxylase is formed by P0, P1, P2, P3, P4 and P5 polypeptides.

Structurei

3D structure databases

ProteinModelPortaliP19732.
SMRiP19732. Positions 7-500.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Family and domain databases

Gene3Di1.10.620.20. 1 hit.
InterProiIPR009078. Ferritin-like_SF.
IPR003430. Phenol_Hydrox.
IPR012348. RNR-rel.
IPR007029. YHS_dom.
[Graphical view]
PfamiPF02332. Phenol_Hydrox. 1 hit.
PF04945. YHS. 1 hit.
[Graphical view]
SUPFAMiSSF47240. SSF47240. 1 hit.

Sequencei

Sequence statusi: Complete.

P19732-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MATHNKKRLN LKDKYRYLTR DLAWETTYQK KEDVFPLEHF EGIKITDWDK
60 70 80 90 100
WEDPFRLTMD TYWKYQAEKE KKLYAIFDAF AQNNGHQNIS DARYVNALKL
110 120 130 140 150
FLTAVSPLEY QAFQGFSRVG RQFSGAGARV ACQMQAIDEL RHVQTQVHAM
160 170 180 190 200
SHYNKHFDGL HDFAHMYDRV WYLSVPKSYM DDARTAGPFE FLTAVSFSFE
210 220 230 240 250
YVLTNLLFVP FMSGAAYNGD MATVTFGFSA QSDEARHMTL GLEVIKFMLE
260 270 280 290 300
QHEDNVPIIQ RWIDKWFWRG YRLLTLIGMM MDYMLPNKVM SWSEAWGVYF
310 320 330 340 350
EQAGGALFKD LERYGIRPPK YVEQTTIGKE HITHQVWGAL YQYSKATSFH
360 370 380 390 400
TWIPGDEELN WLSEKYPDTF DKYYRPRFEF WREQQAKGER FYNDTLPHLC
410 420 430 440 450
QVCQLPVIFT EPDDPTKLSL RSLVHEGERY QFCSDGCCDI FKNEPVKYIQ
460 470 480 490 500
AWLPVHQIYQ GNCEGGDVET VVQKYYHIKS GVDNLEYLGS PEHQRWLALK
510
GQTPPTAAPA DKSLGAA
Length:517
Mass (Da):60,523
Last modified:February 1, 1991 - v1
Checksum:i4EFD4EB40ED73F9C
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
M60276 Genomic DNA. Translation: AAA25942.1.
D28864 Genomic DNA. Translation: BAA06017.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
M60276 Genomic DNA. Translation: AAA25942.1 .
D28864 Genomic DNA. Translation: BAA06017.1 .

3D structure databases

ProteinModelPortali P19732.
SMRi P19732. Positions 7-500.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Enzyme and pathway databases

UniPathwayi UPA00728 .
BioCyci MetaCyc:MONOMER-12797.

Family and domain databases

Gene3Di 1.10.620.20. 1 hit.
InterProi IPR009078. Ferritin-like_SF.
IPR003430. Phenol_Hydrox.
IPR012348. RNR-rel.
IPR007029. YHS_dom.
[Graphical view ]
Pfami PF02332. Phenol_Hydrox. 1 hit.
PF04945. YHS. 1 hit.
[Graphical view ]
SUPFAMi SSF47240. SSF47240. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "Complete nucleotide sequence and polypeptide analysis of multicomponent phenol hydroxylase from Pseudomonas sp. strain CF600."
    Nordlund I., Powlowski J., Shingler V.
    J. Bacteriol. 172:6826-6833(1990) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
  2. Takeo M., Maeda Y., Okada H., Miyama K., Mori K., Ike M., Fujita M.
    Submitted (MAR-1994) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: BH.

Entry informationi

Entry nameiDMPN_PSEUF
AccessioniPrimary (citable) accession number: P19732
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 1, 1991
Last sequence update: February 1, 1991
Last modified: December 11, 2013
This is version 66 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Plasmid

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways

External Data

Dasty 3