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P19732

- DMPN_PSEUF

UniProt

P19732 - DMPN_PSEUF

Protein

Phenol hydroxylase P3 protein

Gene

dmpN

Organism
Pseudomonas sp. (strain CF600)
Status
Reviewed - Annotation score: 3 out of 5- Protein predictedi
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    • History
      Entry version 66 (11 Dec 2013)
      Sequence version 1 (01 Feb 1991)
      Previous versions | rss
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    Functioni

    Catabolizes phenol, and some of its methylated derivatives. P3 is required for growth on phenol, and for in vitro phenol hydroxylase activity.

    Catalytic activityi

    Phenol + NADPH + O2 = catechol + NADP+ + H2O.

    Cofactori

    FAD.
    Fe2+.

    Pathwayi

    GO - Molecular functioni

    1. phenol 2-monooxygenase activity Source: UniProtKB-EC

    GO - Biological processi

    1. phenol-containing compound catabolic process Source: UniProtKB-UniPathway

    Keywords - Molecular functioni

    Monooxygenase, Oxidoreductase

    Keywords - Biological processi

    Aromatic hydrocarbons catabolism

    Keywords - Ligandi

    FAD, Flavoprotein, Iron, NADP

    Enzyme and pathway databases

    BioCyciMetaCyc:MONOMER-12797.
    UniPathwayiUPA00728.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Phenol hydroxylase P3 protein (EC:1.14.13.7)
    Alternative name(s):
    Phenol 2-monooxygenase P3 component
    Gene namesi
    Name:dmpN
    Synonyms:pheA4
    Encoded oniPlasmid pVI1500 Publication
    OrganismiPseudomonas sp. (strain CF600)
    Taxonomic identifieri79676 [NCBI]
    Taxonomic lineageiBacteriaProteobacteria

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 517517Phenol hydroxylase P3 proteinPRO_0000079945Add
    BLAST

    Interactioni

    Subunit structurei

    The multicomponent enzyme phenol hydroxylase is formed by P0, P1, P2, P3, P4 and P5 polypeptides.

    Structurei

    3D structure databases

    ProteinModelPortaliP19732.
    SMRiP19732. Positions 7-500.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Family and domain databases

    Gene3Di1.10.620.20. 1 hit.
    InterProiIPR009078. Ferritin-like_SF.
    IPR003430. Phenol_Hydrox.
    IPR012348. RNR-rel.
    IPR007029. YHS_dom.
    [Graphical view]
    PfamiPF02332. Phenol_Hydrox. 1 hit.
    PF04945. YHS. 1 hit.
    [Graphical view]
    SUPFAMiSSF47240. SSF47240. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    P19732-1 [UniParc]FASTAAdd to Basket

    « Hide

    MATHNKKRLN LKDKYRYLTR DLAWETTYQK KEDVFPLEHF EGIKITDWDK    50
    WEDPFRLTMD TYWKYQAEKE KKLYAIFDAF AQNNGHQNIS DARYVNALKL 100
    FLTAVSPLEY QAFQGFSRVG RQFSGAGARV ACQMQAIDEL RHVQTQVHAM 150
    SHYNKHFDGL HDFAHMYDRV WYLSVPKSYM DDARTAGPFE FLTAVSFSFE 200
    YVLTNLLFVP FMSGAAYNGD MATVTFGFSA QSDEARHMTL GLEVIKFMLE 250
    QHEDNVPIIQ RWIDKWFWRG YRLLTLIGMM MDYMLPNKVM SWSEAWGVYF 300
    EQAGGALFKD LERYGIRPPK YVEQTTIGKE HITHQVWGAL YQYSKATSFH 350
    TWIPGDEELN WLSEKYPDTF DKYYRPRFEF WREQQAKGER FYNDTLPHLC 400
    QVCQLPVIFT EPDDPTKLSL RSLVHEGERY QFCSDGCCDI FKNEPVKYIQ 450
    AWLPVHQIYQ GNCEGGDVET VVQKYYHIKS GVDNLEYLGS PEHQRWLALK 500
    GQTPPTAAPA DKSLGAA 517
    Length:517
    Mass (Da):60,523
    Last modified:February 1, 1991 - v1
    Checksum:i4EFD4EB40ED73F9C
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    M60276 Genomic DNA. Translation: AAA25942.1.
    D28864 Genomic DNA. Translation: BAA06017.1.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    M60276 Genomic DNA. Translation: AAA25942.1 .
    D28864 Genomic DNA. Translation: BAA06017.1 .

    3D structure databases

    ProteinModelPortali P19732.
    SMRi P19732. Positions 7-500.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Enzyme and pathway databases

    UniPathwayi UPA00728 .
    BioCyci MetaCyc:MONOMER-12797.

    Family and domain databases

    Gene3Di 1.10.620.20. 1 hit.
    InterProi IPR009078. Ferritin-like_SF.
    IPR003430. Phenol_Hydrox.
    IPR012348. RNR-rel.
    IPR007029. YHS_dom.
    [Graphical view ]
    Pfami PF02332. Phenol_Hydrox. 1 hit.
    PF04945. YHS. 1 hit.
    [Graphical view ]
    SUPFAMi SSF47240. SSF47240. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "Complete nucleotide sequence and polypeptide analysis of multicomponent phenol hydroxylase from Pseudomonas sp. strain CF600."
      Nordlund I., Powlowski J., Shingler V.
      J. Bacteriol. 172:6826-6833(1990) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    2. Takeo M., Maeda Y., Okada H., Miyama K., Mori K., Ike M., Fujita M.
      Submitted (MAR-1994) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
      Strain: BH.

    Entry informationi

    Entry nameiDMPN_PSEUF
    AccessioniPrimary (citable) accession number: P19732
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: February 1, 1991
    Last sequence update: February 1, 1991
    Last modified: December 11, 2013
    This is version 66 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Plasmid

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways

    External Data

    Dasty 3