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P19730

- DMPL_PSEUF

UniProt

P19730 - DMPL_PSEUF

Protein

Phenol hydroxylase P1 protein

Gene

dmpL

Organism
Pseudomonas sp. (strain CF600)
Status
Reviewed - Annotation score: 4 out of 5- Protein predictedi
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    • History
      Entry version 65 (11 Dec 2013)
      Sequence version 1 (01 Feb 1991)
      Previous versions | rss
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    Functioni

    Catabolizes phenol, and some of its methylated derivatives. P1 is required for growth on phenol, and for in vitro phenol hydroxylase activity.

    Catalytic activityi

    Phenol + NADPH + O2 = catechol + NADP+ + H2O.

    Cofactori

    FAD.
    Fe2+.

    Pathwayi

    GO - Molecular functioni

    1. phenol 2-monooxygenase activity Source: UniProtKB

    GO - Biological processi

    1. aerobic phenol-containing compound catabolic process Source: UniProtKB

    Keywords - Molecular functioni

    Monooxygenase, Oxidoreductase

    Keywords - Biological processi

    Aromatic hydrocarbons catabolism

    Keywords - Ligandi

    FAD, Flavoprotein, Iron, NADP

    Enzyme and pathway databases

    BioCyciMetaCyc:MONOMER-12795.
    UniPathwayiUPA00728.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Phenol hydroxylase P1 protein (EC:1.14.13.7)
    Alternative name(s):
    Phenol 2-monooxygenase P1 component
    Gene namesi
    Name:dmpL
    Synonyms:pheA2
    Encoded oniPlasmid pVI1500 Publication
    OrganismiPseudomonas sp. (strain CF600)
    Taxonomic identifieri79676 [NCBI]
    Taxonomic lineageiBacteriaProteobacteria

    Subcellular locationi

    GO - Cellular componenti

    1. extrachromosomal circular DNA Source: UniProtKB

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 331331Phenol hydroxylase P1 proteinPRO_0000079942Add
    BLAST

    Interactioni

    Subunit structurei

    The multicomponent enzyme phenol hydroxylase is formed by P0, P1, P2, P3, P4 and P5 polypeptides.

    Structurei

    3D structure databases

    ProteinModelPortaliP19730.
    SMRiP19730. Positions 4-329.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Family and domain databases

    Gene3Di1.10.620.20. 1 hit.
    InterProiIPR009078. Ferritin-like_SF.
    IPR012078. MP_mOase_hydro.
    IPR003430. Phenol_Hydrox.
    IPR012348. RNR-rel.
    [Graphical view]
    PfamiPF02332. Phenol_Hydrox. 1 hit.
    [Graphical view]
    PIRSFiPIRSF000040. MMOH_comp. 1 hit.
    SUPFAMiSSF47240. SSF47240. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    P19730-1 [UniParc]FASTAAdd to Basket

    « Hide

    MSVEIKTNTV DPIRQTYGNL QRRFGDKPAS RYQEASYDIE AVTNFHYRPL    50
    WDPQHELHDP TRTAIRMTDW HKVTDPRQFY YGAYVQTRAR MQEATEHAYG 100
    FCEKRELLSR LPAELQAKLL RCLVPLRHAE LGANMNNSSI AGDSIAATVT 150
    QMHIYQAMDR LGMGQYLSRI GLLLDGGTGE ALDQAKAYWL DDPIWQGLRR 200
    YVEDSFVIRD WFELGLAQNL VLDGLLQPLM YQRFDQWLTE NGGSDVAMLT 250
    EFMRDWYGES TRWVDAMFKT VLAENDANRE QVQAWLEVWE PRAYEALLPL 300
    AEEATGIAAL DEVRSAFATR LQKIGLKSRE E 331
    Length:331
    Mass (Da):38,208
    Last modified:February 1, 1991 - v1
    Checksum:i8042F5723BE3A5E8
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    M60276 Genomic DNA. Translation: AAA25940.1.
    D28864 Genomic DNA. Translation: BAA06015.1.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    M60276 Genomic DNA. Translation: AAA25940.1 .
    D28864 Genomic DNA. Translation: BAA06015.1 .

    3D structure databases

    ProteinModelPortali P19730.
    SMRi P19730. Positions 4-329.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Enzyme and pathway databases

    UniPathwayi UPA00728 .
    BioCyci MetaCyc:MONOMER-12795.

    Family and domain databases

    Gene3Di 1.10.620.20. 1 hit.
    InterProi IPR009078. Ferritin-like_SF.
    IPR012078. MP_mOase_hydro.
    IPR003430. Phenol_Hydrox.
    IPR012348. RNR-rel.
    [Graphical view ]
    Pfami PF02332. Phenol_Hydrox. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF000040. MMOH_comp. 1 hit.
    SUPFAMi SSF47240. SSF47240. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "Complete nucleotide sequence and polypeptide analysis of multicomponent phenol hydroxylase from Pseudomonas sp. strain CF600."
      Nordlund I., Powlowski J., Shingler V.
      J. Bacteriol. 172:6826-6833(1990) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    2. Takeo M., Maeda Y., Okada H., Miyama K., Mori K., Ike M., Fujita M.
      Submitted (MAR-1994) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
      Strain: BH.

    Entry informationi

    Entry nameiDMPL_PSEUF
    AccessioniPrimary (citable) accession number: P19730
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: February 1, 1991
    Last sequence update: February 1, 1991
    Last modified: December 11, 2013
    This is version 65 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Plasmid

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways

    External Data

    Dasty 3