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Protein

Major capsid protein

Gene

10

Organism
Enterobacteria phage T3 (Bacteriophage T3)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Assembles with the minor capsid protein to form an icosahedral capsid with a T=7 symmetry, about 60 nm in diameter, and consisting of 415 capsid proteins. The major and minor capsid proteins are incorporated into the capsid in about a 90/10 ratio respectively. Once the capsid formed, encapsidates one single copy of the viral genome.By similarity

Names & Taxonomyi

Protein namesi
Recommended name:
Major capsid proteinUniRule annotation
Alternative name(s):
Gene product 10ABy similarity
Short name:
Gp10ABy similarity
Major head proteinUniRule annotation
Gene namesi
Name:10
OrganismiEnterobacteria phage T3 (Bacteriophage T3)
Taxonomic identifieri10759 [NCBI]
Taxonomic lineageiVirusesdsDNA viruses, no RNA stageCaudoviralesPodoviridaeAutographivirinaeT7virus
Virus hostiEscherichia coli [TaxID: 562]

Subcellular locationi

  • Virion UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Capsid protein, Virion

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001065201 – 347Major capsid proteinAdd BLAST347

Interactioni

Subunit structurei

Homohexamer. Interacts with the connector protein and the minor capsid protein. Interacts with the capsid assembly scaffolding protein; capsid proteins and scaffolding proteins form building blocks that assemble to form the procapsid, each hexamer of the major capsid protein interacting with 2 scaffolding proteins.UniRule annotation

Family & Domainsi

Domaini

The N-terminus interacts with an internal region of the major capsid protein subunit in an adjacent capsomere (intercapsomeric interactions) to stabilize the capsid.UniRule annotation

Sequence similaritiesi

Belongs to the T7virus major capsid protein family.UniRule annotation

Family and domain databases

HAMAPiMF_04119 CAPSID_PROTEIN_T7, 1 hit

Sequences (2)i

Sequence statusi: Complete.

This entry describes 2 isoformsi produced by ribosomal frameshifting. AlignAdd to basket

Isoform Major capsid protein 10A (identifier: P19693-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MANIQGGQQI GTNQGKGQSA ADKLALFLKV FGGEVLTAFA RTSVTMPRHM
60 70 80 90 100
LRSIASGKSA QFPVIGRTKA AYLKPGENLD DKRKDIKHTE KVIHIDGLLT
110 120 130 140 150
ADVLIYDIED AMNHYDVRAE YTAQLGESLA MAADGAVLAE LAGLVNLPDG
160 170 180 190 200
SNENIEGLGK PTVLTLVKPT TGSLTDPVEL GKAIIAQLTI ARASLTKNYV
210 220 230 240 250
PAADRTFYTT PDNYSAILAA LMPNAANYQA LLDPERGTIR NVMGFEVVEV
260 270 280 290 300
PHLTAGGAGD TREDAPADQK HAFPATSSTT VKVALDNVVG LFQHRSAVGT
310 320 330 340
VKLKDLALER ARRANYQADQ IIAKYAMGHG GLRPEAAGAI VLPKVSE
Note: Produced by conventional translation.1 Publication
Length:347
Mass (Da):36,882
Last modified:February 1, 1991 - v1
Checksum:i16F1F9651652E152
GO
Isoform Minor capsid protein 10B (identifier: P19728-1) [UniParc]FASTAAdd to basket
The sequence of this isoform can be found in the external entry P19728.
Isoforms of the same protein are often annotated in two different entries if their sequences differ significantly.
Note: Produced by -1 ribosomal frameshifting.1 Publication
Length:433
Mass (Da):45,353
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X17255 Genomic DNA Translation: CAA35154.1
X15840 Genomic DNA Translation: CAB57820.1
PIRiS04618 VABPA3
RefSeqiNP_523335.1, NC_003298.1 [P19693-1]

Genome annotation databases

GeneIDi927448
KEGGivg:927448

Keywords - Coding sequence diversityi

Ribosomal frameshifting

Similar proteinsi

Entry informationi

Entry nameiCAPSA_BPT3
AccessioniPrimary (citable) accession number: P19693
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 1, 1991
Last sequence update: February 1, 1991
Last modified: April 25, 2018
This is version 50 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health