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P19680

- KPYK_SPICI

UniProt

P19680 - KPYK_SPICI

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Protein

Pyruvate kinase

Gene
pyk
Organism
Spiroplasma citri
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + pyruvate = ADP + phosphoenolpyruvate.

Cofactori

Magnesium.
Potassium.

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei41 – 411Substrate By similarity
Metal bindingi43 – 431Potassium By similarity
Metal bindingi45 – 451Potassium By similarity
Metal bindingi75 – 751Potassium By similarity
Metal bindingi76 – 761Potassium; via carbonyl oxygen By similarity

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. magnesium ion binding Source: InterPro
  3. potassium ion binding Source: InterPro
  4. pyruvate kinase activity Source: UniProtKB-EC

GO - Biological processi

  1. glycolytic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

Kinase, Transferase

Keywords - Biological processi

Glycolysis

Keywords - Ligandi

ATP-binding, Magnesium, Metal-binding, Nucleotide-binding, Pyruvate

Enzyme and pathway databases

UniPathwayiUPA00109; UER00188.

Names & Taxonomyi

Protein namesi
Recommended name:
Pyruvate kinase (EC:2.7.1.40)
Short name:
PK
Gene namesi
Name:pyk
OrganismiSpiroplasma citri
Taxonomic identifieri2133 [NCBI]
Taxonomic lineageiBacteriaTenericutesMollicutesEntomoplasmatalesSpiroplasmataceaeSpiroplasma

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – ›192›192Pyruvate kinasePRO_0000112084Add
BLAST

Structurei

3D structure databases

ProteinModelPortaliP19680.

Family & Domainsi

Sequence similaritiesi

Belongs to the pyruvate kinase family.

Family and domain databases

Gene3Di3.20.20.60. 1 hit.
InterProiIPR001697. Pyr_Knase.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
IPR015793. Pyrv_Knase_brl.
[Graphical view]
PANTHERiPTHR11817. PTHR11817. 1 hit.
PfamiPF00224. PK. 1 hit.
[Graphical view]
SUPFAMiSSF51621. SSF51621. 1 hit.

Sequencei

Sequence statusi: Fragment.

P19680-1 [UniParc]FASTAAdd to Basket

« Hide

MDKFNINEKM KRTKIITTIG PSTHSPGAIE ELFKTGMTTI RLNFSHGDHA    50
EQGARIVWAR EVSAKIGKPI SVLLDTKGPE IHWRIKGLLQ KSLNIYHQMN 100
NSLMFSPSFC KFLHYHYTLL LSKKTKKQLL KIVKKLKKLQ SQHYNLAHGL 150
RETWTSSFCF NERPSIWRLL SSFKQIVTSF KISLVSKVLI KL 192
Length:192
Mass (Da):22,209
Last modified:February 1, 1991 - v1
Checksum:iACF22444BF2CF807
GO

Sequence conflict

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti82 – 192111HWRIK…VLIKL → RAGIMKGGKQEIVAGATVTI YSLPTEYQNREGTGTEITVS YDMSQDLKVGDVVLVDDGKL QLNVTGIKPGIIETKA in AAB69999. 1 PublicationAdd
BLAST

Non-terminal residue

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei192 – 1921

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AF012877 Genomic DNA. Translation: AAB69999.1.
PIRiF35270.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AF012877 Genomic DNA. Translation: AAB69999.1 .
PIRi F35270.

3D structure databases

ProteinModelPortali P19680.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Enzyme and pathway databases

UniPathwayi UPA00109 ; UER00188 .

Family and domain databases

Gene3Di 3.20.20.60. 1 hit.
InterProi IPR001697. Pyr_Knase.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
IPR015793. Pyrv_Knase_brl.
[Graphical view ]
PANTHERi PTHR11817. PTHR11817. 1 hit.
Pfami PF00224. PK. 1 hit.
[Graphical view ]
SUPFAMi SSF51621. SSF51621. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "Organization and nucleotide sequences of the Spiroplasma citri genes for ribosomal protein S2, elongation factor Ts, spiralin, phosphofructokinase, pyruvate kinase, and an unidentified protein."
    Chevalier C., Saillard C., Bove J.M.
    J. Bacteriol. 172:2693-2703(1990) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: ATCC 27556 / NCPPB 2647 / R8A2.
  2. "Gene organization and transcriptional analysis of the Spiroplasma citri rpsB/tsf/x operon."
    Le Dantec L., Bove J.M., Saillard C.
    Curr. Microbiol. 37:269-273(1998) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].

Entry informationi

Entry nameiKPYK_SPICI
AccessioniPrimary (citable) accession number: P19680
Secondary accession number(s): O30600
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 1, 1991
Last sequence update: February 1, 1991
Last modified: June 11, 2014
This is version 78 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3