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P19680 (KPYK_SPICI) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 78. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Pyruvate kinase

Short name=PK
EC=2.7.1.40
Gene names
Name:pyk
OrganismSpiroplasma citri
Taxonomic identifier2133 [NCBI]
Taxonomic lineageBacteriaTenericutesMollicutesEntomoplasmatalesSpiroplasmataceaeSpiroplasma

Protein attributes

Sequence length192 AA.
Sequence statusFragment.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + pyruvate = ADP + phosphoenolpyruvate.

Cofactor

Magnesium.

Potassium.

Pathway

Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 5/5.

Sequence similarities

Belongs to the pyruvate kinase family.

Ontologies

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – ›192›192Pyruvate kinase
PRO_0000112084

Sites

Metal binding431Potassium By similarity
Metal binding451Potassium By similarity
Metal binding751Potassium By similarity
Metal binding761Potassium; via carbonyl oxygen By similarity
Binding site411Substrate By similarity

Experimental info

Sequence conflict82 – 192111HWRIK…VLIKL → RAGIMKGGKQEIVAGATVTI YSLPTEYQNREGTGTEITVS YDMSQDLKVGDVVLVDDGKL QLNVTGIKPGIIETKA in AAB69999. Ref.2
Non-terminal residue1921

Sequences

Sequence LengthMass (Da)Tools
P19680 [UniParc].

Last modified February 1, 1991. Version 1.
Checksum: ACF22444BF2CF807

FASTA19222,209
        10         20         30         40         50         60 
MDKFNINEKM KRTKIITTIG PSTHSPGAIE ELFKTGMTTI RLNFSHGDHA EQGARIVWAR 

        70         80         90        100        110        120 
EVSAKIGKPI SVLLDTKGPE IHWRIKGLLQ KSLNIYHQMN NSLMFSPSFC KFLHYHYTLL 

       130        140        150        160        170        180 
LSKKTKKQLL KIVKKLKKLQ SQHYNLAHGL RETWTSSFCF NERPSIWRLL SSFKQIVTSF 

       190 
KISLVSKVLI KL 

« Hide

References

[1]"Organization and nucleotide sequences of the Spiroplasma citri genes for ribosomal protein S2, elongation factor Ts, spiralin, phosphofructokinase, pyruvate kinase, and an unidentified protein."
Chevalier C., Saillard C., Bove J.M.
J. Bacteriol. 172:2693-2703(1990) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: ATCC 27556 / NCPPB 2647 / R8A2.
[2]"Gene organization and transcriptional analysis of the Spiroplasma citri rpsB/tsf/x operon."
Le Dantec L., Bove J.M., Saillard C.
Curr. Microbiol. 37:269-273(1998) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AF012877 Genomic DNA. Translation: AAB69999.1.
PIRF35270.

3D structure databases

ProteinModelPortalP19680.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Enzyme and pathway databases

UniPathwayUPA00109; UER00188.

Family and domain databases

Gene3D3.20.20.60. 1 hit.
InterProIPR001697. Pyr_Knase.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
IPR015793. Pyrv_Knase_brl.
[Graphical view]
PANTHERPTHR11817. PTHR11817. 1 hit.
PfamPF00224. PK. 1 hit.
[Graphical view]
SUPFAMSSF51621. SSF51621. 1 hit.
ProtoNetSearch...

Entry information

Entry nameKPYK_SPICI
AccessionPrimary (citable) accession number: P19680
Secondary accession number(s): O30600
Entry history
Integrated into UniProtKB/Swiss-Prot: February 1, 1991
Last sequence update: February 1, 1991
Last modified: June 11, 2014
This is version 78 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways