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P19665 (SODF_PORGI) Reviewed, UniProtKB/Swiss-Prot

Last modified July 9, 2014. Version 119. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Superoxide dismutase [Mn/Fe]

EC=1.15.1.1
Gene names
Name:sodB
Ordered Locus Names:PG_1545
OrganismPorphyromonas gingivalis (strain ATCC BAA-308 / W83) [Complete proteome] [HAMAP]
Taxonomic identifier242619 [NCBI]
Taxonomic lineageBacteriaBacteroidetesBacteroidiaBacteroidalesPorphyromonadaceaePorphyromonas

Protein attributes

Sequence length191 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.

Catalytic activity

2 superoxide + 2 H+ = O2 + H2O2.

Cofactor

Binds 1 manganese or iron ion per subunit.

Subunit structure

Homodimer.

Sequence similarities

Belongs to the iron/manganese superoxide dismutase family.

Ontologies

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 191191Superoxide dismutase [Mn/Fe]
PRO_0000159993

Sites

Metal binding271Manganese or iron
Metal binding741Manganese or iron
Metal binding1571Manganese or iron
Metal binding1611Manganese or iron

Experimental info

Sequence conflict131D → Y in AAA25651. Ref.2
Sequence conflict291G → E AA sequence Ref.3
Sequence conflict1121N → D in AAA25651. Ref.2

Secondary structure

................................... 191
Helix Strand Turn

Details...

Sequences

Sequence LengthMass (Da)Tools
P19665 [UniParc].

Last modified May 1, 1991. Version 2.
Checksum: AA53419397BF6BA1

FASTA19121,501
        10         20         30         40         50         60 
MTHELISLPY AVDALAPVIS KETVEFHHGK HLKTYVDNLN KLIIGTEFEN ADLNTIVQKS 

        70         80         90        100        110        120 
EGGIFNNAGQ TLNHNLYFTQ FRPGKGGAPK GKLGEAIDKQ FGSFEKFKEE FNTAGTTLFG 

       130        140        150        160        170        180 
SGWVWLASDA NGKLSIEKEP NAGNPVRKGL NPLLGFDVWE HAYYLTYQNR RADHLKDLWS 

       190 
IVDWDIVESR Y 

« Hide

References

« Hide 'large scale' references
[1]"The superoxide dismutase-encoding gene of the obligately anaerobic bacterium Bacteroides gingivalis."
Nakayama K.
Gene 96:149-150(1990) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
[2]"Isolation, expression, and nucleotide sequence of the sod gene from Porphyromonas gingivalis."
Choi J.I., Takahashi N., Kato T., Kuramitsu H.K.
Infect. Immun. 59:1564-1566(1991) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
[3]"The primary structure of superoxide dismutase purified from anaerobically maintained Bacteroides gingivalis."
Amano A., Shizukuishi S., Tsunemitsu A., Maekawa K., Tsunasawa S.
FEBS Lett. 272:217-220(1990) [PubMed] [Europe PMC] [Abstract]
Cited for: PROTEIN SEQUENCE.
Strain: 381.
[4]"Complete genome sequence of the oral pathogenic bacterium Porphyromonas gingivalis strain W83."
Nelson K.E., Fleischmann R.D., DeBoy R.T., Paulsen I.T., Fouts D.E., Eisen J.A., Daugherty S.C., Dodson R.J., Durkin A.S., Gwinn M.L., Haft D.H., Kolonay J.F., Nelson W.C., Mason T.M., Tallon L., Gray J., Granger D., Tettelin H. expand/collapse author list , Dong H., Galvin J.L., Duncan M.J., Dewhirst F.E., Fraser C.M.
J. Bacteriol. 185:5591-5601(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC BAA-308 / W83.
[5]"Characterization of superoxide dismutases purified from either anaerobically maintained or aerated Bacteroides gingivalis."
Amano A., Shizukuishi S., Tamagawa H., Iwakura K., Tsunasawa S., Tsunemitsu A.
J. Bacteriol. 172:1457-1463(1990) [PubMed] [Europe PMC] [Abstract]
Cited for: PROTEIN SEQUENCE OF 1-12.
[6]"Crystal structure of cambialistic superoxide dismutase from Porphyromonas gingivalis."
Sugio S., Hiraoka B.Y., Yamakura F.
Eur. J. Biochem. 267:3487-3495(2000) [PubMed] [Europe PMC] [Abstract]
Cited for: X-RAY CRYSTALLOGRAPHY (1.8 ANGSTROMS).
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
D90152 Genomic DNA. Translation: BAA14182.1.
M60401 Genomic DNA. Translation: AAA25651.1.
AE015924 Genomic DNA. Translation: AAQ66583.1.
PIRA43585.
RefSeqNP_905684.1. NC_002950.2.

3D structure databases

PDBe
RCSB-PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
1QNNX-ray1.80A/B/C/D1-191[»]
1UERX-ray1.60A/B/C/D1-191[»]
1UESX-ray1.60A/B/C/D1-191[»]
ProteinModelPortalP19665.
SMRP19665. Positions 1-191.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING242619.PG1545.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAQ66583; AAQ66583; PG_1545.
GeneID2553021.
KEGGpgi:PG1545.
PATRIC22974068. VBIPorGin26334_0556.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0605.
KOK04564.
OMAHANRELQ.
OrthoDBEOG63NMNT.

Enzyme and pathway databases

BioCycPGIN242619:GHX8-1394-MONOMER.

Family and domain databases

InterProIPR001189. Mn/Fe_SOD.
IPR019833. Mn/Fe_SOD_BS.
IPR019832. Mn/Fe_SOD_C.
IPR019831. Mn/Fe_SOD_N.
[Graphical view]
PANTHERPTHR11404. PTHR11404. 1 hit.
PfamPF02777. Sod_Fe_C. 1 hit.
PF00081. Sod_Fe_N. 1 hit.
[Graphical view]
PIRSFPIRSF000349. SODismutase. 1 hit.
PRINTSPR01703. MNSODISMTASE.
SUPFAMSSF46609. SSF46609. 1 hit.
SSF54719. SSF54719. 1 hit.
PROSITEPS00088. SOD_MN. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

EvolutionaryTraceP19665.

Entry information

Entry nameSODF_PORGI
AccessionPrimary (citable) accession number: P19665
Entry history
Integrated into UniProtKB/Swiss-Prot: February 1, 1991
Last sequence update: May 1, 1991
Last modified: July 9, 2014
This is version 119 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PDB cross-references

Index of Protein Data Bank (PDB) cross-references