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Protein

Thymidine phosphorylase

Gene

deoA

Organism
Lactobacillus rhamnosus
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis.

Catalytic activityi

Thymidine + phosphate = thymine + 2-deoxy-alpha-D-ribose 1-phosphate.

GO - Molecular functioni

Keywordsi

Molecular functionGlycosyltransferase, Transferase

Names & Taxonomyi

Protein namesi
Recommended name:
Thymidine phosphorylase (EC:2.4.2.4)
Alternative name(s):
TdRPase
Gene namesi
Name:deoA
OrganismiLactobacillus rhamnosus
Taxonomic identifieri47715 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesLactobacillaceaeLactobacillus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000590771 – ›23Thymidine phosphorylaseAdd BLAST›23

Interactioni

Subunit structurei

Homodimer.1 Publication

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiENOG4105C17 Bacteria
COG0057 LUCA

Family and domain databases

InterProiView protein in InterPro
IPR020828 GlycerAld_3-P_DH_NAD(P)-bd
IPR036291 NAD(P)-bd_dom_sf
PfamiView protein in Pfam
PF00044 Gp_dh_N, 1 hit
SUPFAMiSSF51735 SSF51735, 1 hit

Sequencei

Sequence statusi: Fragment.

P19663-1 [UniParc]FASTAAdd to basket

« Hide

        10         20 
MVKIGINEFG RIGRLAFRRI YEL
Length:23
Mass (Da):2,752
Last modified:February 1, 1991 - v1
Checksum:i8705C9C4D82C1AD7
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei231

Sequence databases

PIRiS11384

Similar proteinsi

Entry informationi

Entry nameiTYPH_LACRH
AccessioniPrimary (citable) accession number: P19663
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 1, 1991
Last sequence update: February 1, 1991
Last modified: May 23, 2018
This is version 83 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Direct protein sequencing

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