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P19656 (NLTP_MAIZE) Reviewed, UniProtKB/Swiss-Prot

Last modified March 19, 2014. Version 93. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Alt products·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Non-specific lipid-transfer protein

Short name=LTP
Alternative name(s):
Phospholipid transfer protein
Short name=PLTP
Allergen=Zea m 14
OrganismZea mays (Maize)
Taxonomic identifier4577 [NCBI]
Taxonomic lineageEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaePACMAD cladePanicoideaeAndropogoneaeZea

Protein attributes

Sequence length120 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Plant non-specific lipid-transfer proteins transfer phospholipids as well as galactolipids across membranes. May play a role in wax or cutin deposition in the cell walls of expanding epidermal cells and certain secretory tissues.

Allergenic properties

Causes an allergic reaction in human.

Sequence similarities

Belongs to the plant LTP family.

Ontologies

Keywords
   Biological processTransport
   Coding sequence diversityAlternative splicing
   DiseaseAllergen
   DomainSignal
   LigandLipid-binding
   PTMDisulfide bond
   Technical term3D-structure
Direct protein sequencing
Gene Ontology (GO)
   Biological_processlipid transport

Inferred from electronic annotation. Source: InterPro

   Cellular_componentapoplast

Inferred from electronic annotation. Source: EnsemblPlants/Gramene

chloroplast thylakoid

Inferred from electronic annotation. Source: EnsemblPlants/Gramene

plant-type cell wall

Inferred from electronic annotation. Source: EnsemblPlants/Gramene

plasma membrane

Inferred from electronic annotation. Source: EnsemblPlants/Gramene

   Molecular_functionlipid binding

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Alternative products

This entry describes 2 isoforms produced by alternative splicing. [Align] [Select]
Isoform 1 (identifier: P19656-1)

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.
Isoform 2 (identifier: P19656-2)

Also known as: long;

The sequence of this isoform differs from the canonical sequence as follows:
     119-120: VN → YSRRMHASAD

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 2727 Ref.1
Chain28 – 12093Non-specific lipid-transfer protein
PRO_0000018389

Amino acid modifications

Disulfide bond31 ↔ 79 By similarity
Disulfide bond41 ↔ 56 By similarity
Disulfide bond57 ↔ 102 By similarity
Disulfide bond77 ↔ 116 By similarity

Natural variations

Alternative sequence119 – 1202VN → YSRRMHASAD in isoform 2.
VSP_003147

Secondary structure

............... 120
Helix Strand Turn

Details...

Sequences

Sequence LengthMass (Da)Tools
Isoform 1 [UniParc].

Last modified February 1, 1991. Version 1.
Checksum: 28F27EBAE3910218

FASTA12011,705
        10         20         30         40         50         60 
MARTQQLAVV ATAVVALVLL AAATSEAAIS CGQVASAIAP CISYARGQGS GPSAGCCSGV 

        70         80         90        100        110        120 
RSLNNAARTT ADRRAACNCL KNAAAGVSGL NAGNAASIPS KCGVSIPYTI STSTDCSRVN 

« Hide

Isoform 2 (long) [UniParc].

Checksum: C9921F66B1F43762
Show »

FASTA12812,667

References

[1]"Phospholipid transfer protein: full-length cDNA and amino acid sequence in maize. Amino acid sequence homologies between plant phospholipid transfer proteins."
Tchang F., This P., Stiefel V., Arondel V., Morch M.-D., Pages M., Puigdomenech P., Grellet F., Delseny M., Bouillon P., Huet J.-C., Guerbette F., Beauvais-Cante F., Duranton H., Pernollet J.-C., Kader J.-C.
J. Biol. Chem. 263:16849-16855(1988) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [MRNA], PROTEIN SEQUENCE OF 28-120.
Tissue: Seed.
[2]"Multiple mRNA coding for phospholipid-transfer protein from Zea mays arise from alternative splicing."
Arondel V., Tchang F., Baillet B., Vignols F., Grellet F., Delseny M., Kader J.-C., Puigdomenech P.
Gene 99:133-136(1991) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [MRNA].
[3]"High-resolution crystal structure of the non-specific lipid-transfer protein from maize seedlings."
Shin D.H., Lee J.Y., Hwang K.Y., Kim K.K., Suh S.W.
Structure 3:189-199(1995) [PubMed] [Europe PMC] [Abstract]
Cited for: X-RAY CRYSTALLOGRAPHY (1.9 ANGSTROMS).
[4]"Two-dimensional 1H-NMR studies of maize lipid-transfer protein. Sequence-specific assignment and secondary structure."
Petit M.-C., Sodano P., Marion D., Ptak M.
Eur. J. Biochem. 222:1047-1054(1994) [PubMed] [Europe PMC] [Abstract]
Cited for: STRUCTURE BY NMR.
[5]"Solution structure and lipid binding of a nonspecific lipid transfer protein extracted from maize seeds."
Gomar J., Petit M.-C., Sodano P., Sy D., Marion D., Kader J.-C., Vovelle F., Ptak M.
Protein Sci. 5:565-577(1996) [PubMed] [Europe PMC] [Abstract]
Cited for: STRUCTURE BY NMR.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
J04176 mRNA. Translation: AAA33493.1.
M57249 mRNA. Translation: AAA33494.1.
PIRA31779.
S45635.
RefSeqNP_001105311.1. NM_001111841.1.
UniGeneZm.89638.

3D structure databases

PDBe
RCSB PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
1AFHNMR-A28-120[»]
1FK0X-ray1.80A28-120[»]
1FK1X-ray1.80A28-120[»]
1FK2X-ray1.80A28-120[»]
1FK3X-ray1.80A28-120[»]
1FK4X-ray1.80A28-120[»]
1FK5X-ray1.30A28-120[»]
1FK6X-ray1.90A28-120[»]
1FK7X-ray1.90A28-120[»]
1MZLX-ray1.90A28-120[»]
1MZMX-ray1.78A28-120[»]
ProteinModelPortalP19656.
SMRP19656. Positions 28-120.
ModBaseSearch...
MobiDBSearch...

Protein family/group databases

Allergome3534. Zea m 14.0101.
3535. Zea m 14.0102.
684. Zea m 14.

Proteomic databases

PRIDEP19656.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID542231.
KEGGzma:542231.

Organism-specific databases

GrameneP19656.
MaizeGDB25447.

Family and domain databases

InterProIPR016140. Bifunc_inhib/LTP/seed_store.
IPR000528. Plant_LTP.
[Graphical view]
PfamPF00234. Tryp_alpha_amyl. 1 hit.
[Graphical view]
PRINTSPR00382. LIPIDTRNSFER.
SMARTSM00499. AAI. 1 hit.
[Graphical view]
SUPFAMSSF47699. SSF47699. 1 hit.
PROSITEPS00597. PLANT_LTP. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

EvolutionaryTraceP19656.

Entry information

Entry nameNLTP_MAIZE
AccessionPrimary (citable) accession number: P19656
Entry history
Integrated into UniProtKB/Swiss-Prot: February 1, 1991
Last sequence update: February 1, 1991
Last modified: March 19, 2014
This is version 93 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PDB cross-references

Index of Protein Data Bank (PDB) cross-references

Allergens

Nomenclature of allergens and list of entries