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P19570

- GUN3_BACCJ

UniProt

P19570 - GUN3_BACCJ

Protein

Endoglucanase C

Gene

celC

Organism
Bacillus cellulosilyticus (strain ATCC 21833 / DSM 2522 / FERM P-1141 / JCM 9156 / N-4)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 87 (01 Oct 2014)
      Sequence version 1 (01 Feb 1991)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    Endohydrolysis of (1->4)-beta-D-glucosidic linkages in cellulose, lichenin and cereal beta-D-glucans.

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei219 – 2191Proton donorBy similarity
    Active sitei335 – 3351NucleophileBy similarity

    GO - Molecular functioni

    1. cellulase activity Source: UniProtKB-EC

    GO - Biological processi

    1. cellulose catabolic process Source: UniProtKB-KW

    Keywords - Molecular functioni

    Glycosidase, Hydrolase

    Keywords - Biological processi

    Carbohydrate metabolism, Cellulose degradation, Polysaccharide degradation

    Protein family/group databases

    CAZyiCBM17. Carbohydrate-Binding Module Family 17.
    CBM28. Carbohydrate-Binding Module Family 28.
    GH5. Glycoside Hydrolase Family 5.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Endoglucanase C (EC:3.2.1.4)
    Alternative name(s):
    Cellulase C
    Endo-1,4-beta-glucanase C
    Gene namesi
    Name:celC
    OrganismiBacillus cellulosilyticus (strain ATCC 21833 / DSM 2522 / FERM P-1141 / JCM 9156 / N-4)
    Taxonomic identifieri649639 [NCBI]
    Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillus

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Signal peptidei1 – 2828Sequence AnalysisAdd
    BLAST
    Chaini29 – 825797Endoglucanase CPRO_0000007836Add
    BLAST

    Structurei

    3D structure databases

    ProteinModelPortaliP19570.
    SMRiP19570. Positions 68-429, 615-796.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Keywords - Domaini

    Signal

    Family and domain databases

    Gene3Di2.60.120.260. 2 hits.
    3.20.20.80. 1 hit.
    InterProiIPR005086. CBM_fam_17/28.
    IPR008979. Galactose-bd-like.
    IPR001547. Glyco_hydro_5.
    IPR018087. Glyco_hydro_5_CS.
    IPR013781. Glyco_hydro_catalytic_dom.
    IPR017853. Glycoside_hydrolase_SF.
    [Graphical view]
    PfamiPF03424. CBM_17_28. 2 hits.
    PF00150. Cellulase. 1 hit.
    [Graphical view]
    SUPFAMiSSF49785. SSF49785. 2 hits.
    SSF51445. SSF51445. 1 hit.
    PROSITEiPS00659. GLYCOSYL_HYDROL_F5. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    P19570-1 [UniParc]FASTAAdd to Basket

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    MRNKLRRLLA IMMAVLLITS LFAPMVSAEE GDNGDDDDLV TPIEIEERPH    50
    ESNYEKYPAL LDGGLDERRP SEAGALQLVE VDGQVTLADQ DGVPIQLRGM 100
    STHGLQWFGE IVNENAFAAL ANDWGSNVIR LALYIGENAY RYNPDLIEKV 150
    YAGIELAKEN DMYVIIDWHV HAPGDPNADI YQGGVNEDGE EYLGAKDFFL 200
    HIAEKYPNDP HLIYELANEP SSNSSGGPGI TNDEDGWEAV REYAQPIVDA 250
    LRDSGNAEDN IIIVGSPNWS QRMDLAAADN PIDDHHTMYT LHFYTGTHEG 300
    TNESYPEGIS SEDRSNVMAN AKYALDKGKA IFATEWGVSE ADGNNGPYLN 350
    EADVWLNFLN ENNISWTNWS LTNKNETSGA FTPFILNESD ATDLDPGEDQ 400
    VWSMEELSVS GEYVRSRILG EEYQPIDRTP REEFSEVIWD FNDGTTQGFV 450
    QNSDSPLDVT IENVNDALQI TGLDESNAIA GEEEDYWSNV RISADEWEET 500
    FDILGAEELS MDVVVDDPTT VAIAAIPQSS AHEWANASNS VLITEDDFEE 550
    QEDGTYKALL TITGEDAPNL TNIAEDPEGS ELNNIILFVG TENADVISLD 600
    NITVTGDRES VPEPVEHDTK GDSALPSDFE DGTRQGWEWD SESAVRTALT 650
    IEEANGSNAL SWEYAYPEVK PSDDWATAPR LTLYKDDLVR GDYEFVAFDF 700
    YIDPIEDRAT EGAIDINLIF QPPAAGYWAQ ASETFEIDLE ELDSATVTDD 750
    GLYHYEVEIN IEDIENDIEL RNLMLIFADD ESDFAGRVFL DNVRMDMSLE 800
    TKVEVLERNI NELQEQLVEV EALMR 825
    Length:825
    Mass (Da):92,015
    Last modified:February 1, 1991 - v1
    Checksum:iA1727DA3D7632617
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    M25500 Genomic DNA. Translation: AAA22306.1.
    PIRiJS0174.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    M25500 Genomic DNA. Translation: AAA22306.1 .
    PIRi JS0174.

    3D structure databases

    ProteinModelPortali P19570.
    SMRi P19570. Positions 68-429, 615-796.
    ModBasei Search...
    MobiDBi Search...

    Protein family/group databases

    CAZyi CBM17. Carbohydrate-Binding Module Family 17.
    CBM28. Carbohydrate-Binding Module Family 28.
    GH5. Glycoside Hydrolase Family 5.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Family and domain databases

    Gene3Di 2.60.120.260. 2 hits.
    3.20.20.80. 1 hit.
    InterProi IPR005086. CBM_fam_17/28.
    IPR008979. Galactose-bd-like.
    IPR001547. Glyco_hydro_5.
    IPR018087. Glyco_hydro_5_CS.
    IPR013781. Glyco_hydro_catalytic_dom.
    IPR017853. Glycoside_hydrolase_SF.
    [Graphical view ]
    Pfami PF03424. CBM_17_28. 2 hits.
    PF00150. Cellulase. 1 hit.
    [Graphical view ]
    SUPFAMi SSF49785. SSF49785. 2 hits.
    SSF51445. SSF51445. 1 hit.
    PROSITEi PS00659. GLYCOSYL_HYDROL_F5. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "The third cellulase of alkalophilic Bacillus sp. strain N-4: evolutionary relationships within the cel gene family."
      Fukumori F., Kudo T., Sashihara N., Nagata Y., Ito K., Horikoshi K.
      Gene 76:289-298(1989) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].

    Entry informationi

    Entry nameiGUN3_BACCJ
    AccessioniPrimary (citable) accession number: P19570
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: February 1, 1991
    Last sequence update: February 1, 1991
    Last modified: October 1, 2014
    This is version 87 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Documents

    1. Glycosyl hydrolases
      Classification of glycosyl hydrolase families and list of entries
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3