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Protein

Tumor rejection antigen P815A

Gene

Trap1a

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Keywordsi

Molecular functionTumor antigen

Names & Taxonomyi

Protein namesi
Recommended name:
Tumor rejection antigen P815A
Gene namesi
Name:Trap1a
Synonyms:P1a
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome X

Organism-specific databases

MGIiMGI:98818. Trap1a.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000656971 – 224Tumor rejection antigen P815AAdd BLAST224

Proteomic databases

PaxDbiP19473.
PRIDEiP19473.

PTM databases

iPTMnetiP19473.
PhosphoSitePlusiP19473.

Expressioni

Tissue specificityi

P185A and B result from the expression by tumor P815 of a gene that is silent or expressed at a very low level in most if not all normal cells of adult mice. Expressed in testis and mastocytoma.

Gene expression databases

BgeeiENSMUSG00000051257.
CleanExiMM_TRAP1A.
ExpressionAtlasiP19473. baseline and differential.
GenevisibleiP19473. MM.

Interactioni

Protein-protein interaction databases

BioGridi204310. 1 interactor.

Structurei

3D structure databases

ProteinModelPortaliP19473.
SMRiP19473.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi5 – 9Nuclear localization signalSequence analysis5

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi83 – 132Asp/Glu-rich (acidic)Add BLAST50
Compositional biasi202 – 215Poly-GluAdd BLAST14

Phylogenomic databases

GeneTreeiENSGT00520000059524.
HOGENOMiHOG000214159.
HOVERGENiHBG018012.
InParanoidiP19473.
OMAiVAWIARQ.
OrthoDBiEOG091G14K3.

Sequencei

Sequence statusi: Complete.

P19473-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSDNKKPDKA HSGSGGDGDG NRCNLLHRYS LEEILPYLGW LVFAVVTTSF
60 70 80 90 100
LALQMFIDAL YEEQYERDVA WIARQSKRMS SVDEDEDDED DEDDYYDDED
110 120 130 140 150
DDDDAFYDDE DDEEEELENL MDDESEDEAE EEMSVEMGAG AEEMGAGANC
160 170 180 190 200
ACVPGHHLRK NEVKCRMIYF FHDPNFLVSI PVNPKEQMEC RCENADEEVA
210 220
MEEEEEEEEE EEEEEMGNPD GFSP
Length:224
Mass (Da):25,758
Last modified:February 1, 1991 - v1
Checksum:i57D97598F2CD6ED2
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M36387 mRNA. Translation: AAA40475.1.
M36386 Genomic DNA. Translation: AAA40474.1.
BC051644 mRNA. Translation: AAH51644.1.
CCDSiCCDS30433.1.
PIRiJH0456.
RefSeqiNP_035765.1. NM_011635.2.
UniGeneiMm.1297.

Genome annotation databases

EnsembliENSMUST00000054534; ENSMUSP00000059448; ENSMUSG00000051257.
GeneIDi22037.
KEGGimmu:22037.
UCSCiuc009uke.1. mouse.

Similar proteinsi

Entry informationi

Entry nameiTUR8_MOUSE
AccessioniPrimary (citable) accession number: P19473
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 1, 1991
Last sequence update: February 1, 1991
Last modified: September 27, 2017
This is version 100 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot