P19450 (BCSC1_GLUXY) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Cellulose synthase operon protein C

Gene names

Name:

bcsC

Organism

Gluconacetobacter xylinus (Acetobacter xylinus)

Taxonomic identifier

28448 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rhodospirillales › Acetobacteraceae › Gluconacetobacter

Protein attributes

Sequence length	1319 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Required for maximal bacterial cellulose synthesis. It may be involved in the formation of a membrane complex for extrusion of the cellulose product.
Pathway	Glycan metabolism; bacterial cellulose biosynthesis.
Subcellular location	Cell outer membrane; Peripheral membrane protein Potential.
Sequence similarities	Belongs to the AcsC/BcsC family. Contains 9 TPR repeats.

Ontologies

Keywords
Biological process	Cellulose biosynthesis
Cellular component	Cell membrane Cell outer membrane Membrane
Domain	Repeat Signal TPR repeat
Gene Ontology (GO)
Biological process	UDP-glucose metabolic process Inferred from electronic annotation. Source: InterPro cellulose biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cell outer membrane Inferred from electronic annotation. Source: UniProtKB-SubCell plasma membrane Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	identical protein binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Signal peptide	1 – 46	46	Potential
	Chain	47 – 1319	1273	Cellulose synthase operon protein C		PRO_0000035686
Regions
	Repeat	49 – 82	34	TPR 1
	Repeat	84 – 116	33	TPR 2
	Repeat	291 – 324	34	TPR 3
	Repeat	325 – 358	34	TPR 4
	Repeat	405 – 438	34	TPR 5
	Repeat	557 – 590	34	TPR 6
	Repeat	701 – 734	34	TPR 7
	Repeat	736 – 768	33	TPR 8
	Repeat	1059 – 1094	36	TPR 9

Sequences

	Sequence		Length	Mass (Da)
	P19450 [UniParc]. Last modified February 1, 1991. Version 1. Checksum: 48C6BEAF6C59A7F7	FASTA	1,319	141,431
	10 20 30 40 50 60 MNRRYVLSLS GALLASSCMT VLVAVPVARA QQASTAMTTA ATSATAAPRQ ILLQQARFWL 70 80 90 100 110 120 QQQQYDNARQ ALQNAERIAP NSPDVLEVLG EYQTAIGNRE AAADTLRHLQ QVAPGSAAAG 130 140 150 160 170 180 NLNDLLSERA ISQSDLSQIR SLAGSGQNAQ AVAGYQKLFH GGKPPHSLAV EYYQTMAGVP 190 200 210 220 230 240 AQWDQARAGL AGVVASNPQD YRAQLAFAQA LTYNTSTRME GLTRLKDLQS FRSQAPVEAA 250 260 270 280 290 300 AAAQSYRQTL SWLPVNPETQ PLMEQWLSAH PNDTALREHM LHPPGGPPDK AGLARQAGYQ 310 320 330 340 350 360 QLNAGRLAAA EQSFQSALQI NSHDADSLGG MGLVSMRQGD TAEARRYFEE AMAADPKTAD 370 380 390 400 410 420 RWRPALAGMA VSGEYASVRQ LIAAHQYTEA KQQLATLARQ PGQYTGATLM LADLQRSTGQ 430 440 450 460 470 480 IAAAEQEYRG ILSREPNNQL ALMGLARVDM AQGNTAEARQ LLSRVGPQYA SQVGEIEVSG 490 500 510 520 530 540 LMAAASQTSD SARKVSILRE AMAQAPRDPW VRINLANALQ QQGDVAEAGR VMQPILANPV 550 560 570 580 590 600 TAQDRQAGIL YTYGSGNDAM TRQLLAGLSP ADYSPAIRSI AEEMEIKQDL ASRLSMVSNP 610 620 630 640 650 660 VPLIREALTQ PDPTGARGVA VADLFRQRGD MVHARMALRI ASTRTIDLSP DQRLSYATEY 670 680 690 700 710 720 MKISNPVAAA RLLAPLGDGT GSATGSALLP EQVQTLQQLR MGISVAQSDL LNQRGDQAQA 730 740 750 760 770 780 YDHLAPALQA DPEATSPKLA LARLYNGHGK PGKALEIDLA VLRHNPQDLD ARQAAVQAAV 790 800 810 820 830 840 NSDHNSLATR LAMDGVQESP MDARAWLAMA VADQADGHGQ RTIEDLRRAY DLRLQQVEGT 850 860 870 880 890 900 RAASGAGAAQ EDALAPPSTN PFRPRGYGHQ TELGAPVTGG SYSAEAASPD TSDQMLSSIA 910 920 930 940 950 960 GQIRTLRENL APSIDGGLGF RSRSGEHGMG RLTEANIPIV GRLPLQAGAS ALTFSITPTM 970 980 990 1000 1010 1020 IWSGNLNTGS VYDVPRYGTM MGVQAYNQYD SYTNAGRDQQ RIAAGTAEAG FAPDVQFGNS 1030 1040 1050 1060 1070 1080 WVRADVGASP IGFPITNVLG GVEFSPRVGP VTFRVSAERR SITNSVLSYG GLRDTNYNSA 1090 1100 1110 1120 1130 1140 LGRYARQVYG QALSKQWGSE WGGVVTNHFH GQVEATLGNT ILYGGGGYAI QTGKNVQRNS 1150 1160 1170 1180 1190 1200 EREAGIGANT LVWHNANMLV RIGVSLTYFG YAKNEDFYTY GQGGYFSPQS YYAATVPVRY 1210 1220 1230 1240 1250 1260 AGQHKRLDWD VTGSVGYQVF HEHSAPFFPT SSLLQSGANT IASNYSASAT PAEYLSEETV 1270 1280 1290 1300 1310 NSAYYPGDSI AGLTGGFNAR VGYRFTRNVR LDLSGRYQKA GNWTESGAMI SAHYLIMDQ

References

[1]

"Genetic organization of the cellulose synthase operon in Acetobacter xylinum." Wong H.C., Fear A.L., Calhoon R.D., Eichinger G.H., Mayer R., Amikam D., Benziman M., Gelfand D.H., Meade J.H., Emerick A.W., Bruner R., Ben-Bassat A., Tal R. Proc. Natl. Acad. Sci. U.S.A. 87:8130-8134(1990) [PubMed: 2146681] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: 1306-3.

Cross-references

Sequence databases
EMBL GenBank DDBJ	M37202 Genomic DNA. Translation: AAA21886.1.
PIR	C43735.
3D structure databases
ProteinModelPortal	P19450.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Family and domain databases
InterPro	IPR008410. BCSC_C. IPR003921. Cell_synth_C. IPR011717. TPR-4. IPR013026. TPR-contain. IPR011990. TPR-like_helical. IPR019734. TPR_repeat. [Graphical view]
Gene3D	G3DSA:1.25.40.10. TPR-like_helical. 5 hits.
Pfam	PF05420. BCSC_C. 1 hit. PF07721. TPR_4. 2 hits. [Graphical view]
PRINTS	PR01441. CELLSNTHASEC.
SMART	SM00028. TPR. 3 hits. [Graphical view]
PROSITE	PS50005. TPR. 7 hits. PS50293. TPR_REGION. 4 hits. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

BCSC1_GLUXY

Accession

Primary (citable) accession number: P19450

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 1, 1991
Last sequence update:	February 1, 1991
Last modified:	May 3, 2011
This is version 73 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program