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Protein

Synaptic vesicle membrane protein VAT-1

Gene
N/A
Organism
Tetronarce californica (Pacific electric ray) (Torpedo californica)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

May play a central role in the functions mediated by specific classes of synaptic vesicles.

Miscellaneous

Synthesized in the neuronal cell bodies and transported to the terminals. Each vesicle contains approximately 28 molecules of VAT-1.

GO - Molecular functioni

Keywordsi

Molecular functionOxidoreductase

Names & Taxonomyi

Protein namesi
Recommended name:
Synaptic vesicle membrane protein VAT-1 (EC:1.-.-.-)
OrganismiTetronarce californica (Pacific electric ray) (Torpedo californica)
Taxonomic identifieri7787 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataChondrichthyesElasmobranchiiBatoideaTorpediniformesTorpedinidaeTetronarce

Subcellular locationi

Keywords - Cellular componenti

Cell junction, Cytoplasmic vesicle, Membrane, Synapse

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001609211 – 379Synaptic vesicle membrane protein VAT-1Add BLAST379

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei273PhosphoserineSequence analysis1

Keywords - PTMi

Phosphoprotein

Expressioni

Tissue specificityi

Cholinergic synaptic vesicles.

Structurei

3D structure databases

ProteinModelPortaliP19333.
SMRiP19333.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

HOVERGENiHBG002466.

Family and domain databases

InterProiView protein in InterPro
IPR013149. ADH_C.
IPR013154. ADH_N.
IPR011032. GroES-like.
IPR036291. NAD(P)-bd_dom_sf.
IPR020843. PKS_ER.
IPR002364. Quin_OxRdtase/zeta-crystal_CS.
PfamiView protein in Pfam
PF08240. ADH_N. 1 hit.
PF00107. ADH_zinc_N. 1 hit.
SMARTiView protein in SMART
SM00829. PKS_ER. 1 hit.
SUPFAMiSSF50129. SSF50129. 1 hit.
SSF51735. SSF51735. 1 hit.
PROSITEiView protein in PROSITE
PS01162. QOR_ZETA_CRYSTAL. 1 hit.

Sequencei

Sequence statusi: Complete.

P19333-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTGEEVKEPK EQQEITEVKE QEPEISYNAI VLNGVGGYDK VKVEVKKGVP
60 70 80 90 100
TLKSDEILVR VQACGLNFSD LLVRQGAFGK HHSLGTECAG VVEAIGDLVI
110 120 130 140 150
DRKVGDKIIM LNIDGGLWTE LVVTTVNRTF LMPDGMSFQE AAAISVNYTA
160 170 180 190 200
AYVMIYDFAN LRPSQSILIH MAAGGVGIAA TQLCKLVHDV TIFGTASPSK
210 220 230 240 250
HETIKENGVT YPIDYTTLDY AEEVRKIAPK GVDIVLDPLG GADDSKGFGL
260 270 280 290 300
LKPLGKLVLY GSANQVTAPK RSSLAAAKVW WHKFNIDALQ LINSNKAVCG
310 320 330 340 350
FHLGRTDPDH VAEVIRKLIS LYKEGKIKPK VDSVWSFEQV GDAMRHMRNT
360 370
RTLEKSSWSL KSRQLMPQLE IKSVSKRQG
Length:379
Mass (Da):41,593
Last modified:November 1, 1990 - v1
Checksum:iFA4ADA17E657F09C
GO

Sequence databases

PIRiJN0013.

Entry informationi

Entry nameiVAT1_TETCF
AccessioniPrimary (citable) accession number: P19333
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1990
Last sequence update: November 1, 1990
Last modified: October 25, 2017
This is version 81 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Direct protein sequencing

Documents

  1. SIMILARITY comments
    Index of protein domains and families