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Protein

Probable nitrate reductase molybdenum cofactor assembly chaperone NarW

Gene

narW

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Chaperone required for proper molybdenum cofactor insertion and final assembly of the membrane-bound respiratory nitrate reductase 2.By similarity

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Chaperone

Keywords - Biological processi

Nitrate assimilation

Enzyme and pathway databases

BioCyciEcoCyc:NARW-MONOMER.
ECOL316407:JW1461-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Probable nitrate reductase molybdenum cofactor assembly chaperone NarW
Alternative name(s):
Redox enzyme maturation protein NarW
Gene namesi
Name:narW
Ordered Locus Names:b1466, JW1461
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG10645. narW.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000967331 – 231Probable nitrate reductase molybdenum cofactor assembly chaperone NarWAdd BLAST231

Proteomic databases

PaxDbiP19317.
PRIDEiP19317.

Interactioni

Binary interactionsi

WithEntry#Exp.IntActNotes
narGP091527EBI-555088,EBI-547248
narYP193183EBI-555088,EBI-555059
narZP193193EBI-555088,EBI-547262

Protein-protein interaction databases

BioGridi4260181. 191 interactors.
DIPiDIP-10321N.
IntActiP19317. 8 interactors.
MINTiMINT-1251853.
STRINGi511145.b1466.

Structurei

3D structure databases

ProteinModelPortaliP19317.
SMRiP19317.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the NarJ/NarW family.Curated

Phylogenomic databases

eggNOGiENOG4108NZN. Bacteria.
COG2180. LUCA.
HOGENOMiHOG000237365.
InParanoidiP19317.
KOiK00373.
OMAiSVTKQIR.
PhylomeDBiP19317.

Family and domain databases

InterProiIPR020945. DMSO/NO3_reduct_chaperone.
IPR003765. NO3_reductase_chaperone_NarJ.
[Graphical view]
PfamiPF02613. Nitrate_red_del. 1 hit.
[Graphical view]
SUPFAMiSSF89155. SSF89155. 1 hit.
TIGRFAMsiTIGR00684. narJ. 1 hit.

Sequencei

Sequence statusi: Complete.

P19317-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MQILKVIGLL MEYPDELLWE CKEDALALIR RDAPMLTDFT HNLLNAPLLD
60 70 80 90 100
KQAEWCEVFD RGRTTSLLLF EHVHAESRDR GQAMVDLLAE YEKVGLQLDC
110 120 130 140 150
RELPDYLPLY LEYLSVLPDD QAKEGLLNVA PILALLGGRL KQREAPWYAL
160 170 180 190 200
FDALLQLAGS SLSSDSVTKQ VNSEERDDTR QALDAVWEEE QVKFIEDNAT
210 220 230
ACDSSPLNQY QRRFSQDVAP QYVDISAGGG K
Length:231
Mass (Da):26,161
Last modified:November 1, 1990 - v1
Checksum:i30AE8EC9AE6290AB
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X17110 Genomic DNA. Translation: CAA34966.1.
U00096 Genomic DNA. Translation: AAC74548.1.
AP009048 Genomic DNA. Translation: BAA15103.1.
PIRiS11429.
RefSeqiNP_415983.1. NC_000913.3.
WP_001166353.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAC74548; AAC74548; b1466.
BAA15103; BAA15103; BAA15103.
GeneIDi946032.
KEGGiecj:JW1461.
eco:b1466.
PATRICi32118224. VBIEscCol129921_1532.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X17110 Genomic DNA. Translation: CAA34966.1.
U00096 Genomic DNA. Translation: AAC74548.1.
AP009048 Genomic DNA. Translation: BAA15103.1.
PIRiS11429.
RefSeqiNP_415983.1. NC_000913.3.
WP_001166353.1. NZ_LN832404.1.

3D structure databases

ProteinModelPortaliP19317.
SMRiP19317.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4260181. 191 interactors.
DIPiDIP-10321N.
IntActiP19317. 8 interactors.
MINTiMINT-1251853.
STRINGi511145.b1466.

Proteomic databases

PaxDbiP19317.
PRIDEiP19317.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC74548; AAC74548; b1466.
BAA15103; BAA15103; BAA15103.
GeneIDi946032.
KEGGiecj:JW1461.
eco:b1466.
PATRICi32118224. VBIEscCol129921_1532.

Organism-specific databases

EchoBASEiEB0639.
EcoGeneiEG10645. narW.

Phylogenomic databases

eggNOGiENOG4108NZN. Bacteria.
COG2180. LUCA.
HOGENOMiHOG000237365.
InParanoidiP19317.
KOiK00373.
OMAiSVTKQIR.
PhylomeDBiP19317.

Enzyme and pathway databases

BioCyciEcoCyc:NARW-MONOMER.
ECOL316407:JW1461-MONOMER.

Miscellaneous databases

PROiP19317.

Family and domain databases

InterProiIPR020945. DMSO/NO3_reduct_chaperone.
IPR003765. NO3_reductase_chaperone_NarJ.
[Graphical view]
PfamiPF02613. Nitrate_red_del. 1 hit.
[Graphical view]
SUPFAMiSSF89155. SSF89155. 1 hit.
TIGRFAMsiTIGR00684. narJ. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiNARW_ECOLI
AccessioniPrimary (citable) accession number: P19317
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1990
Last sequence update: November 1, 1990
Last modified: November 2, 2016
This is version 115 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.