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Protein

Beta-glucanase

Gene

bgc

Organism
Bacillus circulans
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

Hydrolysis of (1->4)-beta-D-glucosidic linkages in beta-D-glucans containing (1->3)- and (1->4)-bonds.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei95 – 951Proton donorBy similarity
Active sitei156 – 1561NucleophilePROSITE-ProRule annotation

GO - Molecular functioni

  1. licheninase activity Source: UniProtKB-EC

GO - Biological processi

  1. carbohydrate metabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Glycosidase, Hydrolase

Protein family/group databases

CAZyiGH8. Glycoside Hydrolase Family 8.

Names & Taxonomyi

Protein namesi
Recommended name:
Beta-glucanase (EC:3.2.1.73)
Alternative name(s):
Endo-beta-1,3-1,4 glucanase
Gene namesi
Name:bgc
OrganismiBacillus circulans
Taxonomic identifieri1397 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 3131Sequence AnalysisAdd
BLAST
Chaini32 – 409378Beta-glucanasePRO_0000007929Add
BLAST

Structurei

3D structure databases

ProteinModelPortaliP19254.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Signal

Family and domain databases

Gene3Di1.50.10.10. 1 hit.
InterProiIPR008928. 6-hairpin_glycosidase-like.
IPR012341. 6hp_glycosidase.
IPR002037. Glyco_hydro_8.
IPR019834. Glyco_hydro_8_CS.
[Graphical view]
PfamiPF01270. Glyco_hydro_8. 1 hit.
[Graphical view]
PRINTSiPR00735. GLHYDRLASE8.
SUPFAMiSSF48208. SSF48208. 1 hit.
PROSITEiPS00812. GLYCOSYL_HYDROL_F8. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P19254-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MRKNRGFSFS SKAVMMCCLA FLLIPASFAF AAPNKPFPQH TTYTSGSIKP
60 70 80 90 100
NHVTQSAMDS SVKAKWDSWK SAYLKTAGTG KYYVKYQSNG DTVSEAHGYG
110 120 130 140 150
MLATVIMAGY DGNAQTYFDG LYQYYKAHPS ANNSKLMAWK QNSSFQNIEG
160 170 180 190 200
ADSATDGDMD IAYSLLLADK QWGSSGSINY LQAGKDIINA IMQSDVNQSQ
210 220 230 240 250
WTLRLGDWAT DNTFKNATRP SDFMLNHLKA FQAATGDARW ANVIDKTYTI
260 270 280 290 300
INSLYSGYSS STGLLPDFVV LSGSTYKPAS ADFLEGANDG SYDYNSCRTP
310 320 330 340 350
WRIATDYLMT GDSRALNQLN QMNSWISAKV SGNPSNVKDG YKLNGTVTGS
360 370 380 390 400
GGSGAFYAPF GVSAMTSSVN QNWLNSVWTK TAGSSNEGYY EDSIKLFSMI

VMSGNWWTY
Length:409
Mass (Da):44,816
Last modified:November 1, 1990 - v1
Checksum:iC7561216F7D13E76
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X52880 Genomic DNA. Translation: CAA37062.1.
PIRiS10485.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X52880 Genomic DNA. Translation: CAA37062.1.
PIRiS10485.

3D structure databases

ProteinModelPortaliP19254.
ModBaseiSearch...
MobiDBiSearch...

Protein family/group databases

CAZyiGH8. Glycoside Hydrolase Family 8.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Family and domain databases

Gene3Di1.50.10.10. 1 hit.
InterProiIPR008928. 6-hairpin_glycosidase-like.
IPR012341. 6hp_glycosidase.
IPR002037. Glyco_hydro_8.
IPR019834. Glyco_hydro_8_CS.
[Graphical view]
PfamiPF01270. Glyco_hydro_8. 1 hit.
[Graphical view]
PRINTSiPR00735. GLHYDRLASE8.
SUPFAMiSSF48208. SSF48208. 1 hit.
PROSITEiPS00812. GLYCOSYL_HYDROL_F8. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Nucleotide sequence of a 1,3-1,4-beta-glucanase-encoding gene in Bacillus circulans WL-12."
    Bueno A., Vasquez de Aldana C.R., Correa J., del Rey F.
    Nucleic Acids Res. 18:4248-4248(1990) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: WL-12.

Entry informationi

Entry nameiGUB_BACCI
AccessioniPrimary (citable) accession number: P19254
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1990
Last sequence update: November 1, 1990
Last modified: October 1, 2014
This is version 68 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Documents

  1. Glycosyl hydrolases
    Classification of glycosyl hydrolase families and list of entries
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.