P19254 (GUB_BACCI) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Beta-glucanase
EC=3.2.1.73

Alternative name(s):
Endo-beta-1,3-1,4 glucanase

Gene names

Name:

bgc

Organism

Bacillus circulans

Taxonomic identifier

1397 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Firmicutes › Bacilli › Bacillales › Bacillaceae › Bacillus

Protein attributes

Sequence length	409 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	Hydrolysis of (1->4)-beta-D-glucosidic linkages in beta-D-glucans containing (1->3)- and (1->4)-bonds.
Sequence similarities	Belongs to the glycosyl hydrolase 8 (cellulase D) family.

Ontologies

Keywords
Domain	Signal
Molecular function	Glycosidase Hydrolase
Gene Ontology (GO)
Biological_process	carbohydrate metabolic process Inferred from electronic annotation. Source: InterPro
Molecular_function	licheninase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Signal peptide	1 – 31	31	Potential
	Chain	32 – 409	378	Beta-glucanase		PRO_0000007929
Sites
	Active site	95	1	Proton donor By similarity
	Active site	156	1	Nucleophile Potential

Sequences

	Sequence		Length	Mass (Da)
	P19254 [UniParc]. Last modified November 1, 1990. Version 1. Checksum: C7561216F7D13E76	FASTA	409	44,816
	10 20 30 40 50 60 MRKNRGFSFS SKAVMMCCLA FLLIPASFAF AAPNKPFPQH TTYTSGSIKP NHVTQSAMDS 70 80 90 100 110 120 SVKAKWDSWK SAYLKTAGTG KYYVKYQSNG DTVSEAHGYG MLATVIMAGY DGNAQTYFDG 130 140 150 160 170 180 LYQYYKAHPS ANNSKLMAWK QNSSFQNIEG ADSATDGDMD IAYSLLLADK QWGSSGSINY 190 200 210 220 230 240 LQAGKDIINA IMQSDVNQSQ WTLRLGDWAT DNTFKNATRP SDFMLNHLKA FQAATGDARW 250 260 270 280 290 300 ANVIDKTYTI INSLYSGYSS STGLLPDFVV LSGSTYKPAS ADFLEGANDG SYDYNSCRTP 310 320 330 340 350 360 WRIATDYLMT GDSRALNQLN QMNSWISAKV SGNPSNVKDG YKLNGTVTGS GGSGAFYAPF 370 380 390 400 GVSAMTSSVN QNWLNSVWTK TAGSSNEGYY EDSIKLFSMI VMSGNWWTY

References

[1]	"Nucleotide sequence of a 1,3-1,4-beta-glucanase-encoding gene in Bacillus circulans WL-12." Bueno A., Vasquez de Aldana C.R., Correa J., del Rey F. Nucleic Acids Res. 18:4248-4248(1990) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: WL-12.

Cross-references

Sequence databases
EMBL GenBank DDBJ	X52880 Genomic DNA. Translation: CAA37062.1.
PIR	S10485.
3D structure databases
ProteinModelPortal	P19254.
ModBase	Search...
Protein family/group databases
CAZy	GH8. Glycoside Hydrolase Family 8.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Family and domain databases
Gene3D	1.50.10.10. 1 hit.
InterPro	IPR008928. 6-hairpin_glycosidase-like. IPR012341. 6hp_glycosidase. IPR002037. Glyco_hydro_8. IPR019834. Glyco_hydro_8_CS. [Graphical view]
Pfam	PF01270. Glyco_hydro_8. 1 hit. [Graphical view]
PRINTS	PR00735. GLHYDRLASE8.
SUPFAM	SSF48208. Glyco_trans_6hp. 1 hit.
PROSITE	PS00812. GLYCOSYL_HYDROL_F8. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

GUB_BACCI

Accession

Primary (citable) accession number: P19254

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 1, 1990
Last sequence update:	November 1, 1990
Last modified:	April 3, 2013
This is version 66 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program