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P19208

- HSP7C_CAEBR

UniProt

P19208 - HSP7C_CAEBR

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Protein

Heat shock 70 kDa protein C

Gene
hsp-3, CBG14829
Organism
Caenorhabditis briggsae
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Probably plays a role in facilitating the assembly of multimeric protein complexes inside the ER By similarity.

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW

GO - Biological processi

  1. response to stress Source: UniProtKB-KW
Complete GO annotation...

Keywords - Biological processi

Stress response

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Heat shock 70 kDa protein C
Gene namesi
Name:hsp-3
ORF Names:CBG14829
OrganismiCaenorhabditis briggsae
Taxonomic identifieri6238 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
ProteomesiUP000008549: Chromosome X, UP000008549: Unassembled WGS sequence

Organism-specific databases

WormBaseiCBG14829; CBP03479; WBGene00035220; Cbr-hsp-3.

Subcellular locationi

GO - Cellular componenti

  1. endoplasmic reticulum lumen Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Endoplasmic reticulum

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 1717 Reviewed predictionAdd
BLAST
Chaini18 – 661644Heat shock 70 kDa protein CPRO_0000013540Add
BLAST

Proteomic databases

PRIDEiP19208.

Interactioni

Protein-protein interaction databases

STRINGi6238.CBG14829.

Structurei

3D structure databases

ProteinModelPortaliP19208.
SMRiP19208. Positions 33-575.

Family & Domainsi

Motif

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Motifi658 – 6614Prevents secretion from ER

Sequence similaritiesi

Keywords - Domaini

Signal

Phylogenomic databases

eggNOGiCOG0443.
HOGENOMiHOG000228135.
KOiK09490.
OMAiDKRAVQK.
OrthoDBiEOG780RKX.

Family and domain databases

Gene3Di1.20.1270.10. 1 hit.
2.60.34.10. 1 hit.
InterProiIPR018181. Heat_shock_70_CS.
IPR029048. HSP70_C.
IPR029047. HSP70_peptide-bd.
IPR013126. Hsp_70_fam.
[Graphical view]
PfamiPF00012. HSP70. 1 hit.
[Graphical view]
PRINTSiPR00301. HEATSHOCK70.
SUPFAMiSSF100920. SSF100920. 1 hit.
SSF100934. SSF100934. 1 hit.
PROSITEiPS00014. ER_TARGET. 1 hit.
PS00297. HSP70_1. 1 hit.
PS00329. HSP70_2. 1 hit.
PS01036. HSP70_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P19208-1 [UniParc]FASTAAdd to Basket

« Hide

MKTLFLLGLI ALTAVSVYCE EEEKTEKKET KYGTIIGIDL GTTYSCVGVY    50
KNGRVEIIAN DQGNRITPSY VAFSGEQGDR LIGDAAKNQL TINPENTIFD 100
AKRLIGRDYN DKTVQADIKH WPFKVLDKSN KPSVEVKVGA DNKQFTPEEV 150
SAMVLVKMKE IAESYLGKEV KHAVVTVPAY FNDAQRQATK DAGTIAGLNV 200
VRIINEPTAA AIAYGLDKKD GERNILVFDL GGGTFDVSML TIDNGVFEVL 250
ATNGDTHLGG EDFDQRVMEY FIKLYKKKSG KDLRKDKRAV QKLRREVEKA 300
KRALSTQHQT KVEIESLFDG EDFSETLTRA KFEELNMDLF RATLKPVQKV 350
LEDSDLKKDD VHEIVLVGGS TRIPKVQQLI KEFFNGKEPS RGINPDEAVA 400
YGAAVQGGVI SGEEDTGEIV LLDVNPLTMG IETVGGVMTK LISRNTVIPT 450
KKSQVFSTAA DNQPTVTIQV FEGERPMTKD NHQLGKFDLT GIPPAPRGVP 500
QIEVTFEIDV NGILHVTAED KGTGNKNKIT ITNDQNRLSP EDIERMINDA 550
EKFAEDDKKV KEKAEARNEL ESYAYSLKNQ IGDKEKLGGK LDEDDKKTIE 600
EAVDEAISWL GSNADASAEE LKEQKKELEG KVQPIVSKLY KDGGAGGEEA 650
PEEGSDDKDE L 661
Length:661
Mass (Da):72,945
Last modified:February 1, 2005 - v2
Checksum:i4358AA747A128F0D
GO

Sequence conflict

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti126 – 1261L → F in AAA28075. 1 Publication
Sequence conflicti140 – 1401A → S in AAA28075. 1 Publication
Sequence conflicti183 – 1831D → V in AAA28075. 1 Publication
Sequence conflicti189 – 1913TKD → LKY in AAA28075. 1 Publication
Sequence conflicti196 – 1961A → V in AAA28075. 1 Publication

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
HE600983 Genomic DNA. Translation: CAP33250.1.
M26906 Genomic DNA. Translation: AAA28075.1.
RefSeqiXP_002644811.1. XM_002644765.1.

Genome annotation databases

EnsemblMetazoaiCBG14829; CBG14829; CBG14829.
GeneIDi8586807.
KEGGicbr:CBG14829.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
HE600983 Genomic DNA. Translation: CAP33250.1 .
M26906 Genomic DNA. Translation: AAA28075.1 .
RefSeqi XP_002644811.1. XM_002644765.1.

3D structure databases

ProteinModelPortali P19208.
SMRi P19208. Positions 33-575.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 6238.CBG14829.

Proteomic databases

PRIDEi P19208.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblMetazoai CBG14829 ; CBG14829 ; CBG14829 .
GeneIDi 8586807.
KEGGi cbr:CBG14829.

Organism-specific databases

CTDi 8586807.
WormBasei CBG14829 ; CBP03479 ; WBGene00035220 ; Cbr-hsp-3.

Phylogenomic databases

eggNOGi COG0443.
HOGENOMi HOG000228135.
KOi K09490.
OMAi DKRAVQK.
OrthoDBi EOG780RKX.

Family and domain databases

Gene3Di 1.20.1270.10. 1 hit.
2.60.34.10. 1 hit.
InterProi IPR018181. Heat_shock_70_CS.
IPR029048. HSP70_C.
IPR029047. HSP70_peptide-bd.
IPR013126. Hsp_70_fam.
[Graphical view ]
Pfami PF00012. HSP70. 1 hit.
[Graphical view ]
PRINTSi PR00301. HEATSHOCK70.
SUPFAMi SSF100920. SSF100920. 1 hit.
SSF100934. SSF100934. 1 hit.
PROSITEi PS00014. ER_TARGET. 1 hit.
PS00297. HSP70_1. 1 hit.
PS00329. HSP70_2. 1 hit.
PS01036. HSP70_3. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: AF16.
  2. "Functional elements and domains inferred from sequence comparisons of a heat shock gene in two nematodes."
    Heschl M.F.P., Baillie D.L.
    J. Mol. Evol. 31:3-9(1990) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-441.

Entry informationi

Entry nameiHSP7C_CAEBR
AccessioniPrimary (citable) accession number: P19208
Secondary accession number(s): A8XKS6, Q617T9
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1990
Last sequence update: February 1, 2005
Last modified: June 11, 2014
This is version 99 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programCaenorhabditis annotation project

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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