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Protein

Baseplate wedge protein gp6

Gene

6

Organism
Enterobacteria phage T4 (Bacteriophage T4)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Baseplate protein that is located next to the tail tube (inner baseplate) (PubMed:27193680). Involved in the tail assembly (PubMed:21129200). The gp25-(gp6)2-gp7 module is involved in sheath contraction (PubMed:27193680).1 Publication2 Publications

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Viral tail assembly, Virus exit from host cell

Protein family/group databases

TCDBi1.K.1.1.1. the gp27/5 t4-baseplate (t4-bp) family.

Names & Taxonomyi

Protein namesi
Recommended name:
Baseplate wedge protein gp6UniRule annotationCurated
Alternative name(s):
Gene product 6
Short name:
gp6
Gene namesi
Name:6
OrganismiEnterobacteria phage T4 (Bacteriophage T4)
Taxonomic identifieri10665 [NCBI]
Taxonomic lineageiVirusesdsDNA viruses, no RNA stageCaudoviralesMyoviridaeTevenvirinaeT4likevirus
Virus hostiEscherichia coli [TaxID: 562]
Proteomesi
  • UP000009087 Componenti: Genome

Subcellular locationi

GO - Cellular componenti

  • virion Source: CACAO
  • virus tail, baseplate Source: UniProtKB
Complete GO annotation...

Keywords - Cellular componenti

Viral baseplate protein, Viral tail protein, Virion

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001649961 – 660Baseplate wedge protein gp6Add BLAST660

Expressioni

Inductioni

Expressed in the late phase of the viral replicative cycle.UniRule annotation

Interactioni

Subunit structurei

Homodimer (PubMed:2403438, PubMed:19896486, PubMed:27193680); each gp6 molecule in the ring interacts with its two neighbors, forming an N-terminal dimer with one and a C-terminal dimer with the other (PubMed:27193680). Heterotrimer with gp7; gp6 is part of a (gp6)2-gp7 heterotrimeric molecule (PubMed:27193680). The (gp6)2-gp7 heterotrimeric molecule further interacts with gp25 and gp53; the gp25-(gp6)2-gp7 module is involved in sheath contraction (PubMed:27193680). Part of the baseplate macromolecular complex which consists of gp5, gp5.4, gp27 (central spike complex); gp6, gp25, gp53 (inner baseplate); gp7, gp8 (intermediate baseplate); gp9, gp10, gp11, gp12 (peripheral); gp48 and gp54 (proximal region of the tail tube) (PubMed:27193680).3 Publications

Protein-protein interaction databases

DIPiDIP-48306N.

Structurei

Secondary structure

1660
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Helixi342 – 352Combined sources11
Turni353 – 355Combined sources3
Beta strandi359 – 364Combined sources6
Beta strandi371 – 377Combined sources7
Beta strandi379 – 382Combined sources4
Turni384 – 388Combined sources5
Beta strandi389 – 391Combined sources3
Helixi393 – 396Combined sources4
Beta strandi403 – 409Combined sources7
Beta strandi412 – 425Combined sources14
Turni426 – 428Combined sources3
Helixi433 – 451Combined sources19
Helixi461 – 469Combined sources9
Beta strandi477 – 479Combined sources3
Beta strandi482 – 489Combined sources8
Beta strandi515 – 518Combined sources4
Beta strandi535 – 542Combined sources8
Beta strandi549 – 556Combined sources8
Turni560 – 562Combined sources3
Beta strandi590 – 596Combined sources7
Turni597 – 600Combined sources4
Beta strandi601 – 605Combined sources5
Helixi606 – 608Combined sources3
Helixi613 – 615Combined sources3
Beta strandi621 – 625Combined sources5
Beta strandi630 – 633Combined sources4
Beta strandi636 – 640Combined sources5
Turni644 – 646Combined sources3
Beta strandi650 – 653Combined sources4

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
3H2TX-ray3.20A/B334-660[»]
3H3Welectron microscopy12.00A/B/C/D/E/F/G/H/I/J/K/L334-660[»]
3H3Yelectron microscopy16.00A/B/C/D/E/F/G/H/I/J/K/L334-660[»]
5HX2electron microscopy3.80D/E1-660[»]
5IV5electron microscopy4.11A/B/BH/BI/EA/EB/GD/GE/X/Y/u/v1-660[»]
5IV7electron microscopy6.77A/B/BF/BG/EA/EB/Q/R/g/h/w/x1-660[»]
SMRiP19060.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP19060.

Family & Domainsi

Sequence similaritiesi

Belongs to the T4likevirus baseplate wedge protein gp6 family.UniRule annotation

Family and domain databases

HAMAPiMF_04102. BP06_T4. 1 hit.

Sequencei

Sequence statusi: Complete.

P19060-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MANTPVNYQL TRTANAIPEI FVGGTFAEIK QNLIEWLNGQ NEFLDYDFEG
60 70 80 90 100
SRLNVLCDLL AYNTLYIQQF GNAAVYESFM RTANLRSSVV QAAQDNGYLP
110 120 130 140 150
TSKSAAQTEI MLTCTDALNR NYITIPRGTR FLAYAKDTSV NPYNFVSRED
160 170 180 190 200
VIAIRDKNNQ YFPRLKLAQG RIVRTEIIYD KLTPIIIYDK NIDRNQVKLY
210 220 230 240 250
VDGAEWINWT RKSMVHAGST STIYYMRETI DGNTEFYFGE GEISVNASEG
260 270 280 290 300
ALTANYIGGL KPTQNSTIVI EYISTNGADA NGAVGFSYAD TLTNITVINI
310 320 330 340 350
NENPNDDPDF VGADGGGDPE DIERIRELGT IKRETQQRCV TATDYDTFVS
360 370 380 390 400
ERFGSIIQAV QTFTDSTKPG YAFIAAKPKS GLYLTTVQRE DIKNYLKDYN
410 420 430 440 450
LAPITPSIIS PNYLFIKTNL KVTYALNKLQ ESEQWLEGQI IDKIDRYYTE
460 470 480 490 500
DVEIFNSSFA KSKMLTYVDD ADHSVIGSSA TIQMVREVQN FYKTPEAGIK
510 520 530 540 550
YNNQIKDRSM ESNTFSFNSG RKVVNPDTGL EEDVLYDVRI VSTDRDSKGI
560 570 580 590 600
GKVIIGPFAS GDVTENENIQ PYTGNDFNKL ANSDGRDKYY VIGEINYPAD
610 620 630 640 650
VIYWNIAKIN LTSEKFEVQT IELYSDPTDD VIFTRDGSLI VFENDLRPQY
660
LTIDLEPISQ
Length:660
Mass (Da):74,429
Last modified:November 1, 1990 - v1
Checksum:iDD233D4F26A7C1BF
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X15907 Genomic DNA. Translation: CAA34021.1.
AF158101 Genomic DNA. Translation: AAD42505.1.
PIRiJQ0656. G6BPT4.
RefSeqiNP_049764.1. NC_000866.4.

Genome annotation databases

GeneIDi1258662.
KEGGivg:1258662.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X15907 Genomic DNA. Translation: CAA34021.1.
AF158101 Genomic DNA. Translation: AAD42505.1.
PIRiJQ0656. G6BPT4.
RefSeqiNP_049764.1. NC_000866.4.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
3H2TX-ray3.20A/B334-660[»]
3H3Welectron microscopy12.00A/B/C/D/E/F/G/H/I/J/K/L334-660[»]
3H3Yelectron microscopy16.00A/B/C/D/E/F/G/H/I/J/K/L334-660[»]
5HX2electron microscopy3.80D/E1-660[»]
5IV5electron microscopy4.11A/B/BH/BI/EA/EB/GD/GE/X/Y/u/v1-660[»]
5IV7electron microscopy6.77A/B/BF/BG/EA/EB/Q/R/g/h/w/x1-660[»]
SMRiP19060.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

DIPiDIP-48306N.

Protein family/group databases

TCDBi1.K.1.1.1. the gp27/5 t4-baseplate (t4-bp) family.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi1258662.
KEGGivg:1258662.

Miscellaneous databases

EvolutionaryTraceiP19060.

Family and domain databases

HAMAPiMF_04102. BP06_T4. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiBP06_BPT4
AccessioniPrimary (citable) accession number: P19060
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1990
Last sequence update: November 1, 1990
Last modified: November 2, 2016
This is version 69 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.