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P18891

- LECF_ALEAU

UniProt

P18891 - LECF_ALEAU

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Protein
Fucose-specific lectin
Gene
N/A
Organism
Aleuria aurantia (Orange peel mushroom)
Status
Reviewed - Annotation score: 3 out of 5 - Experimental evidence at protein leveli

Functioni

Might have a role in the differentiation of cells. Binds L-fucose.

Keywords - Ligandi

Lectin

Names & Taxonomyi

Protein namesi
Recommended name:
Fucose-specific lectin
Alternative name(s):
Aleuria aurantia lectin
Short name:
AAL
OrganismiAleuria aurantia (Orange peel mushroom)
Taxonomic identifieri5188 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaPezizomycetesPezizalesPyronemataceaeAleuria

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Initiator methioninei1 – 11Removed1 Publication
Chaini2 – 313312Fucose-specific lectin
PRO_0000084401Add
BLAST

Expressioni

Developmental stagei

A.aurentia forms a fruiting body, and AAL is detected in fruiting bodies but not in mycelia.

Keywords - Developmental stagei

Fruiting body

Interactioni

Subunit structurei

Homodimer.

Structurei

Secondary structure

Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Beta strandi11 – 166
Beta strandi23 – 308
Beta strandi33 – 419
Helixi51 – 533
Beta strandi54 – 574
Beta strandi65 – 717
Beta strandi74 – 829
Beta strandi87 – 9610
Beta strandi98 – 1003
Helixi102 – 1065
Beta strandi117 – 1226
Beta strandi124 – 1274
Beta strandi130 – 1356
Beta strandi143 – 16422
Beta strandi169 – 1757
Beta strandi178 – 1858
Beta strandi188 – 19811
Beta strandi200 – 2089
Beta strandi214 – 2207
Turni221 – 2244
Beta strandi225 – 2317
Beta strandi237 – 24610
Beta strandi250 – 2523
Beta strandi268 – 2725
Turni273 – 2753
Beta strandi276 – 2838
Turni284 – 2863
Beta strandi287 – 2948
Turni295 – 2973
Beta strandi298 – 3014

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1IUBX-ray2.31A2-313[»]
1IUCX-ray2.24A2-313[»]
1OFZX-ray1.50A/B2-313[»]
ProteinModelPortaliP18891.
SMRiP18891. Positions 2-313.

Miscellaneous databases

EvolutionaryTraceiP18891.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Repeati2 – 55541
Add
BLAST
Repeati56 – 107522
Add
BLAST
Repeati108 – 159523
Add
BLAST
Repeati160 – 209504
Add
BLAST
Repeati210 – 257485
Add
BLAST
Repeati258 – 313566
Add
BLAST

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni2 – 3133126 X approximate tandem repeats
Add
BLAST

Keywords - Domaini

Repeat

Family and domain databases

InterProiIPR012475. Fungal_lectin.
[Graphical view]
PfamiPF07938. Fungal_lectin. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P18891-1 [UniParc]FASTAAdd to Basket

« Hide

MPTEFLYTSK IAAISWAATG GRQQRVYFQD LNGKIREAQR GGDNPWTGGS    50
SQNVIGEAKL FSPLAAVTWK SAQGIQIRVY CVNKDNILSE FVYDGSKWIT 100
GQLGSVGVKV GSNSKLAALQ WGGSESAPPN IRVYYQKSNG SGSSIHEYVW 150
SGKWTAGASF GSTVPGTGIG ATAIGPGRLR IYYQATDNKI REHCWDSNSW 200
YVGGFSASAS AGVSIAAISW GSTPNIRVYW QKGREELYEA AYGGSWNTPG 250
QIKDASRPTP SLPDTFIAAN SSGNIDISVF FQASGVSLQQ WQWISGKGWS 300
IGAVVPTGTP AGW 313
Length:313
Mass (Da):33,529
Last modified:January 23, 2007 - v3
Checksum:i06839A365AA0CAE5
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
D00573 mRNA. Translation: BAA00451.1.
D85776 Genomic DNA. Translation: BAA12871.1.
PIRiJX0096.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
D00573 mRNA. Translation: BAA00451.1 .
D85776 Genomic DNA. Translation: BAA12871.1 .
PIRi JX0096.

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
Entry Method Resolution (Å) Chain Positions PDBsum
1IUB X-ray 2.31 A 2-313 [» ]
1IUC X-ray 2.24 A 2-313 [» ]
1OFZ X-ray 1.50 A/B 2-313 [» ]
ProteinModelPortali P18891.
SMRi P18891. Positions 2-313.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Miscellaneous databases

EvolutionaryTracei P18891.

Family and domain databases

InterProi IPR012475. Fungal_lectin.
[Graphical view ]
Pfami PF07938. Fungal_lectin. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Primary structure of a fucose-specific lectin obtained from a mushroom, Aleuria aurantia."
    Fukumori F., Takeuchi N., Hagiwara T., Ohbayashi H., Endo T., Kochibe N., Nagata Y., Kobata A.
    J. Biochem. 107:190-196(1990) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA].
  2. Ogawa S., Ando A., Nagata Y.
    Submitted (JUN-1996) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
  3. "Cloning and expression of a functional fucose-specific lectin from an orange peel mushroom, Aleuria aurantia."
    Fukumori F., Takeuchi N., Hagiwara T., Ito K., Kochibe N., Kobata A., Nagata Y.
    FEBS Lett. 250:153-156(1989) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE OF 4-31, PROTEIN SEQUENCE OF 2-31.

Entry informationi

Entry nameiLECF_ALEAU
AccessioniPrimary (citable) accession number: P18891
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1990
Last sequence update: January 23, 2007
Last modified: July 9, 2014
This is version 58 of the entry and version 3 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Direct protein sequencing

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references

External Data

Dasty 3