Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

P18824

- ARM_DROME

UniProt

P18824 - ARM_DROME

Protein

Armadillo segment polarity protein

Gene

arm

Organism
Drosophila melanogaster (Fruit fly)
Status
Reviewed - Annotation score: 5 out of 5- Experimental evidence at protein leveli
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 167 (01 Oct 2014)
      Sequence version 1 (01 Nov 1990)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Isoform neural may associate with CadN and participate in the transmission of developmental information. Can associate with alpha-catenin. Isoform cytoplasmic accumulates through wg signaling; arm function in wg signal transduction is required early in development for determination of neuroblast fate. Arm and Abl proteins function cooperatively at adherens junctions in both the CNS and epidermis.1 Publication

    GO - Molecular functioni

    1. alpha-catenin binding Source: RefGenome
    2. cadherin binding Source: RefGenome
    3. cytoskeletal protein binding Source: FlyBase
    4. kinase binding Source: FlyBase
    5. protein binding Source: UniProtKB
    6. protein complex binding Source: FlyBase
    7. protein kinase binding Source: RefGenome
    8. structural molecule activity Source: RefGenome
    9. transcription coactivator activity Source: FlyBase
    10. transcription factor binding Source: UniProtKB

    GO - Biological processi

    1. branch fusion, open tracheal system Source: FlyBase
    2. branching morphogenesis of an epithelial tube Source: FlyBase
    3. cell adhesion Source: FlyBase
    4. cell fate determination Source: FlyBase
    5. cell morphogenesis Source: FlyBase
    6. chitin-based larval cuticle pattern formation Source: FlyBase
    7. compound eye morphogenesis Source: FlyBase
    8. compound eye retinal cell programmed cell death Source: FlyBase
    9. cuticle pattern formation Source: FlyBase
    10. cytoskeletal anchoring at plasma membrane Source: RefGenome
    11. delamination Source: FlyBase
    12. dorsal closure Source: FlyBase
    13. epithelial cell type specification, open tracheal system Source: FlyBase
    14. establishment or maintenance of cell polarity Source: FlyBase
    15. heart development Source: FlyBase
    16. heart formation Source: FlyBase
    17. imaginal disc-derived wing expansion Source: FlyBase
    18. long-term memory Source: FlyBase
    19. negative regulation of heart induction by canonical Wnt signaling pathway Source: FlyBase
    20. negative regulation of transcription from RNA polymerase II promoter Source: RefGenome
    21. nervous system development Source: FlyBase
    22. neuroblast development Source: FlyBase
    23. neuroblast fate commitment Source: UniProtKB
    24. oocyte development Source: RefGenome
    25. oocyte localization involved in germarium-derived egg chamber formation Source: FlyBase
    26. oogenesis Source: FlyBase
    27. ovarian follicle cell development Source: FlyBase
    28. photoreceptor cell differentiation Source: FlyBase
    29. positive regulation of transcription, DNA-templated Source: FlyBase
    30. positive regulation of transcription from RNA polymerase II promoter Source: FlyBase
    31. protein localization to adherens junction Source: FlyBase
    32. protein localization to plasma membrane Source: FlyBase
    33. regulation of cell shape Source: FlyBase
    34. segment polarity determination Source: UniProtKB-KW
    35. single organismal cell-cell adhesion Source: FlyBase
    36. somatic stem cell maintenance Source: FlyBase
    37. ventral furrow formation Source: FlyBase
    38. wing disc morphogenesis Source: FlyBase
    39. Wnt signaling pathway Source: FlyBase
    40. zonula adherens assembly Source: FlyBase

    Keywords - Molecular functioni

    Developmental protein, Segmentation polarity protein

    Keywords - Biological processi

    Cell adhesion, Wnt signaling pathway

    Enzyme and pathway databases

    ReactomeiREACT_184321. Ca2+ pathway.
    REACT_184323. LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production.
    REACT_207070. TCF dependent signaling in response to WNT.
    REACT_218447. formation of the beta-catenin:TCF transactivating complex.
    REACT_220429. disassembly of the destruction complex and recruitment of AXIN to the membrane.
    SignaLinkiP18824.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Armadillo segment polarity protein
    Gene namesi
    Name:arm
    ORF Names:CG11579
    OrganismiDrosophila melanogaster (Fruit fly)
    Taxonomic identifieri7227 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
    ProteomesiUP000000803: Chromosome X

    Organism-specific databases

    FlyBaseiFBgn0000117. arm.

    Subcellular locationi

    Cytoplasm 1 Publication. Cell membrane 1 Publication; Peripheral membrane protein 1 Publication; Cytoplasmic side 1 Publication. Cell junctionadherens junction By similarity
    Note: Inner surface of cell membrane and adherens junction.

    GO - Cellular componenti

    1. adherens junction Source: UniProtKB
    2. apical plasma membrane Source: FlyBase
    3. apicolateral plasma membrane Source: FlyBase
    4. axon Source: FlyBase
    5. basolateral plasma membrane Source: RefGenome
    6. catenin complex Source: RefGenome
    7. cytoplasm Source: FlyBase
    8. cytoplasmic side of plasma membrane Source: RefGenome
    9. cytosol Source: RefGenome
    10. desmosome Source: RefGenome
    11. endocytic vesicle Source: FlyBase
    12. fascia adherens Source: RefGenome
    13. nucleus Source: FlyBase
    14. spot adherens junction Source: FlyBase
    15. transcription factor complex Source: RefGenome
    16. Z disc Source: RefGenome
    17. zonula adherens Source: FlyBase

    Keywords - Cellular componenti

    Cell junction, Cell membrane, Cytoplasm, Membrane

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 843843Armadillo segment polarity proteinPRO_0000064292Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Modified residuei650 – 6501Phosphothreonine2 Publications
    Modified residuei688 – 6881Phosphoserine2 Publications
    Modified residuei694 – 6941Phosphoserine2 Publications

    Post-translational modificationi

    Phosphorylated on Ser, Thr and Tyr residues. Level of phosphorylation varies both during embryonic development and from embryonic tissue to tissue. Sgg is required for phosphorylation and wg signal negatively regulates arm phosphorylation. Hypophosphorylated form of arm increases in steady-state levels.2 Publications

    Keywords - PTMi

    Phosphoprotein

    Proteomic databases

    PaxDbiP18824.
    PRIDEiP18824.

    Expressioni

    Tissue specificityi

    Isoform cytoplasmic accumulates at low levels in axons, at high levels in specific cells along the CNS midline and in leg and eye imaginal disks. Isoform neural accumulates in the axon tracts of the CNS. Both isoforms accumulate in the peripheral nervous system.1 Publication

    Developmental stagei

    Present at all stages, but reaches the highest levels during early to mid-embryogenesis. Isoform cytoplasmic is the predominant one from the cellular blastoderm stage until germ-band retraction. Isoform neural is first seen after germ band retraction.

    Gene expression databases

    BgeeiP18824.

    Interactioni

    Subunit structurei

    Interacts with Mer and Moe at the adherens junction. Interacts with Inx2.2 Publications

    Binary interactionsi

    WithEntry#Exp.IntActNotes
    BCL9O005123EBI-216128,EBI-533127From a different organism.
    ebd1Q9W0N93EBI-216128,EBI-141287
    IswiQ243682EBI-216128,EBI-367628
    lgsQ961D95EBI-216128,EBI-85519
    nejO013683EBI-216128,EBI-868028
    panP919432EBI-216128,EBI-147301

    Protein-protein interaction databases

    BioGridi57697. 71 interactions.
    DIPiDIP-19968N.
    IntActiP18824. 14 interactions.
    MINTiMINT-344131.

    Structurei

    3D structure databases

    ProteinModelPortaliP18824.
    SMRiP18824. Positions 78-678.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Repeati159 – 20042ARM 1Add
    BLAST
    Repeati201 – 24242ARM 2Add
    BLAST
    Repeati243 – 28442ARM 3Add
    BLAST
    Repeati285 – 32642ARM 4Add
    BLAST
    Repeati327 – 36842ARM 5Add
    BLAST
    Repeati369 – 41042ARM 6Add
    BLAST
    Repeati411 – 44939ARM 7Add
    BLAST
    Repeati450 – 49647ARM 8Add
    BLAST
    Repeati497 – 53842ARM 9Add
    BLAST
    Repeati539 – 58446ARM 10Add
    BLAST
    Repeati585 – 60824ARM 11Add
    BLAST
    Repeati609 – 64739ARM 12Add
    BLAST
    Repeati648 – 68942ARM 13; truncatedAdd
    BLAST

    Compositional bias

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Compositional biasi1 – 158158Asp/Glu-rich (acidic)Add
    BLAST
    Compositional biasi690 – 843154Asp/Glu-rich (acidic)Add
    BLAST

    Sequence similaritiesi

    Belongs to the beta-catenin family.Curated
    Contains 13 ARM repeats.PROSITE-ProRule annotation

    Keywords - Domaini

    Repeat

    Phylogenomic databases

    eggNOGiNOG297695.
    GeneTreeiENSGT00730000110821.
    InParanoidiP18824.
    KOiK02105.
    OMAiRESHNRA.
    OrthoDBiEOG7X9G6B.
    PhylomeDBiP18824.

    Family and domain databases

    Gene3Di1.25.10.10. 1 hit.
    InterProiIPR011989. ARM-like.
    IPR016024. ARM-type_fold.
    IPR000225. Armadillo.
    IPR013284. Beta-catenin.
    [Graphical view]
    PfamiPF00514. Arm. 4 hits.
    [Graphical view]
    PRINTSiPR01869. BCATNINFAMLY.
    SMARTiSM00185. ARM. 12 hits.
    [Graphical view]
    SUPFAMiSSF48371. SSF48371. 1 hit.
    PROSITEiPS50176. ARM_REPEAT. 9 hits.
    [Graphical view]

    Sequences (2)i

    Sequence statusi: Complete.

    This entry describes 2 isoformsi produced by alternative splicing. Align

    Isoform Cytoplasmic (identifier: P18824-1) [UniParc]FASTAAdd to Basket

    Also known as: A, B

    This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

    « Hide

    MSYMPAQNRT MSHNNQYNPP DLPPMVSAKE QTLMWQQNSY LGDSGIHSGA    50
    VTQVPSLSGK EDEEMEGDPL MFDLDTGFPQ NFTQDQVDDM NQQLSQTRSQ 100
    RVRAAMFPET LEEGIEIPST QFDPQQPTAV QRLSEPSQML KHAVVNLINY 150
    QDDAELATRA IPELIKLLND EDQVVVSQAA MMVHQLSKKE ASRHAIMNSP 200
    QMVAALVRAI SNSNDLESTK AAVGTLHNLS HHRQGLLAIF KSGGIPALVK 250
    LLSSPVESVL FYAITTLHNL LLHQDGSKMA VRLAGGLQKM VTLLQRNNVK 300
    FLAIVTDCLQ ILAYGNQESK LIILASGGPN ELVRIMRSYD YEKLLWTTSR 350
    VLKVLSVCSS NKPAIVDAGG MQALAMHLGN MSPRLVQNCL WTLRNLSDAA 400
    TKVEGLEALL QSLVQVLGST DVNVVTCAAG ILSNLTCNNQ RNKATVCQVG 450
    GVDALVRTII NAGDREEITE PAVCALRHLT SRHVDSELAQ NAVRLNYGLS 500
    VIVKLLHPPS RWPLIKAVIG LIRNLALCPA NHAPLREHGA IHHLVRLLMR 550
    AFQDTERQRS SIATTGSQQP SAYADGVRME EIVEGTVGAL HILARESHNR 600
    ALIRQQSVIP IFVRLLFNEI ENIQRVAAGV LCELAADKEG AEIIEQEGAT 650
    GPLTDLLHSR NEGVATYAAA VLFRMSEDKP QDYKKRLSIE LTNSLLREDN 700
    NIWANADLGM GPDLQDMLGP EEAYEGLYGQ GPPSVHSSHG GRAFHQQGYD 750
    TLPIDSMQGL EISSPVGGGG AGGAPGNGGA VGGASGGGGN IGAIPPSGAP 800
    TSPYSMDMDV GEIDAGALNF DLDAMPTPPN DNNNLAAWYD TDC 843
    Length:843
    Mass (Da):91,153
    Last modified:November 1, 1990 - v1
    Checksum:i40DAD6FB83163049
    GO
    Isoform Neural (identifier: P18824-2) [UniParc]FASTAAdd to Basket

    Also known as: C

    The sequence of this isoform differs from the canonical sequence as follows:
         718-843: LGPEEAYEGL...NLAAWYDTDC → ILYQ

    Show »
    Length:721
    Mass (Da):79,314
    Checksum:i0E19594766E0847F
    GO

    Alternative sequence

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Alternative sequencei718 – 843126LGPEE…YDTDC → ILYQ in isoform Neural. 1 PublicationVSP_006738Add
    BLAST

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    X54468 Genomic DNA. Translation: CAA38350.1.
    AF001213 mRNA. Translation: AAB58731.1.
    AE014298 Genomic DNA. Translation: AAF45686.2.
    AE014298 Genomic DNA. Translation: AAF45687.2.
    AE014298 Genomic DNA. Translation: AAN09064.2.
    AE014298 Genomic DNA. Translation: AAS65246.1.
    AL021106, AL021086 Genomic DNA. Translation: CAA15946.1.
    AL021086, AL021106 Genomic DNA. Translation: CAA15935.1.
    AY118525 mRNA. Translation: AAM49894.1.
    PIRiT12689.
    RefSeqiNP_001259149.1. NM_001272220.1. [P18824-1]
    NP_476665.2. NM_057317.4. [P18824-1]
    NP_476666.1. NM_057318.3. [P18824-1]
    NP_599100.1. NM_134273.2. [P18824-1]
    NP_726775.2. NM_166912.2. [P18824-2]
    NP_996328.1. NM_206605.2. [P18824-1]
    UniGeneiDm.4782.

    Genome annotation databases

    EnsemblMetazoaiFBtr0089988; FBpp0089031; FBgn0000117. [P18824-1]
    FBtr0089989; FBpp0089032; FBgn0000117. [P18824-1]
    FBtr0089991; FBpp0089034; FBgn0000117. [P18824-1]
    FBtr0089992; FBpp0089035; FBgn0000117. [P18824-1]
    FBtr0332583; FBpp0304835; FBgn0000117. [P18824-1]
    GeneIDi31151.
    KEGGidme:Dmel_CG11579.

    Keywords - Coding sequence diversityi

    Alternative splicing

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    X54468 Genomic DNA. Translation: CAA38350.1 .
    AF001213 mRNA. Translation: AAB58731.1 .
    AE014298 Genomic DNA. Translation: AAF45686.2 .
    AE014298 Genomic DNA. Translation: AAF45687.2 .
    AE014298 Genomic DNA. Translation: AAN09064.2 .
    AE014298 Genomic DNA. Translation: AAS65246.1 .
    AL021106 , AL021086 Genomic DNA. Translation: CAA15946.1 .
    AL021086 , AL021106 Genomic DNA. Translation: CAA15935.1 .
    AY118525 mRNA. Translation: AAM49894.1 .
    PIRi T12689.
    RefSeqi NP_001259149.1. NM_001272220.1. [P18824-1 ]
    NP_476665.2. NM_057317.4. [P18824-1 ]
    NP_476666.1. NM_057318.3. [P18824-1 ]
    NP_599100.1. NM_134273.2. [P18824-1 ]
    NP_726775.2. NM_166912.2. [P18824-2 ]
    NP_996328.1. NM_206605.2. [P18824-1 ]
    UniGenei Dm.4782.

    3D structure databases

    ProteinModelPortali P18824.
    SMRi P18824. Positions 78-678.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    BioGridi 57697. 71 interactions.
    DIPi DIP-19968N.
    IntActi P18824. 14 interactions.
    MINTi MINT-344131.

    Proteomic databases

    PaxDbi P18824.
    PRIDEi P18824.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblMetazoai FBtr0089988 ; FBpp0089031 ; FBgn0000117 . [P18824-1 ]
    FBtr0089989 ; FBpp0089032 ; FBgn0000117 . [P18824-1 ]
    FBtr0089991 ; FBpp0089034 ; FBgn0000117 . [P18824-1 ]
    FBtr0089992 ; FBpp0089035 ; FBgn0000117 . [P18824-1 ]
    FBtr0332583 ; FBpp0304835 ; FBgn0000117 . [P18824-1 ]
    GeneIDi 31151.
    KEGGi dme:Dmel_CG11579.

    Organism-specific databases

    CTDi 31151.
    FlyBasei FBgn0000117. arm.

    Phylogenomic databases

    eggNOGi NOG297695.
    GeneTreei ENSGT00730000110821.
    InParanoidi P18824.
    KOi K02105.
    OMAi RESHNRA.
    OrthoDBi EOG7X9G6B.
    PhylomeDBi P18824.

    Enzyme and pathway databases

    Reactomei REACT_184321. Ca2+ pathway.
    REACT_184323. LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production.
    REACT_207070. TCF dependent signaling in response to WNT.
    REACT_218447. formation of the beta-catenin:TCF transactivating complex.
    REACT_220429. disassembly of the destruction complex and recruitment of AXIN to the membrane.
    SignaLinki P18824.

    Miscellaneous databases

    ChiTaRSi arm. drosophila.
    GenomeRNAii 31151.
    NextBioi 772169.
    PROi P18824.

    Gene expression databases

    Bgeei P18824.

    Family and domain databases

    Gene3Di 1.25.10.10. 1 hit.
    InterProi IPR011989. ARM-like.
    IPR016024. ARM-type_fold.
    IPR000225. Armadillo.
    IPR013284. Beta-catenin.
    [Graphical view ]
    Pfami PF00514. Arm. 4 hits.
    [Graphical view ]
    PRINTSi PR01869. BCATNINFAMLY.
    SMARTi SM00185. ARM. 12 hits.
    [Graphical view ]
    SUPFAMi SSF48371. SSF48371. 1 hit.
    PROSITEi PS50176. ARM_REPEAT. 9 hits.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Molecular analysis of the armadillo locus: uniformly distributed transcripts and a protein with novel internal repeats are associated with a Drosophila segment polarity gene."
      Riggleman B., Wieschaus E., Schedl P.
      Genes Dev. 3:96-113(1989) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
      Strain: Oregon-R.
      Tissue: Embryo.
    2. "Roles of Armadillo, a Drosophila catenin, during central nervous system development."
      Loureiro J., Peifer M.
      Curr. Biol. 8:622-632(1998) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS CYTOPLASMIC AND NEURAL), FUNCTION, TISSUE SPECIFICITY.
      Tissue: Head.
    3. "The genome sequence of Drosophila melanogaster."
      Adams M.D., Celniker S.E., Holt R.A., Evans C.A., Gocayne J.D., Amanatides P.G., Scherer S.E., Li P.W., Hoskins R.A., Galle R.F., George R.A., Lewis S.E., Richards S., Ashburner M., Henderson S.N., Sutton G.G., Wortman J.R., Yandell M.D.
      , Zhang Q., Chen L.X., Brandon R.C., Rogers Y.-H.C., Blazej R.G., Champe M., Pfeiffer B.D., Wan K.H., Doyle C., Baxter E.G., Helt G., Nelson C.R., Miklos G.L.G., Abril J.F., Agbayani A., An H.-J., Andrews-Pfannkoch C., Baldwin D., Ballew R.M., Basu A., Baxendale J., Bayraktaroglu L., Beasley E.M., Beeson K.Y., Benos P.V., Berman B.P., Bhandari D., Bolshakov S., Borkova D., Botchan M.R., Bouck J., Brokstein P., Brottier P., Burtis K.C., Busam D.A., Butler H., Cadieu E., Center A., Chandra I., Cherry J.M., Cawley S., Dahlke C., Davenport L.B., Davies P., de Pablos B., Delcher A., Deng Z., Mays A.D., Dew I., Dietz S.M., Dodson K., Doup L.E., Downes M., Dugan-Rocha S., Dunkov B.C., Dunn P., Durbin K.J., Evangelista C.C., Ferraz C., Ferriera S., Fleischmann W., Fosler C., Gabrielian A.E., Garg N.S., Gelbart W.M., Glasser K., Glodek A., Gong F., Gorrell J.H., Gu Z., Guan P., Harris M., Harris N.L., Harvey D.A., Heiman T.J., Hernandez J.R., Houck J., Hostin D., Houston K.A., Howland T.J., Wei M.-H., Ibegwam C., Jalali M., Kalush F., Karpen G.H., Ke Z., Kennison J.A., Ketchum K.A., Kimmel B.E., Kodira C.D., Kraft C.L., Kravitz S., Kulp D., Lai Z., Lasko P., Lei Y., Levitsky A.A., Li J.H., Li Z., Liang Y., Lin X., Liu X., Mattei B., McIntosh T.C., McLeod M.P., McPherson D., Merkulov G., Milshina N.V., Mobarry C., Morris J., Moshrefi A., Mount S.M., Moy M., Murphy B., Murphy L., Muzny D.M., Nelson D.L., Nelson D.R., Nelson K.A., Nixon K., Nusskern D.R., Pacleb J.M., Palazzolo M., Pittman G.S., Pan S., Pollard J., Puri V., Reese M.G., Reinert K., Remington K., Saunders R.D.C., Scheeler F., Shen H., Shue B.C., Siden-Kiamos I., Simpson M., Skupski M.P., Smith T.J., Spier E., Spradling A.C., Stapleton M., Strong R., Sun E., Svirskas R., Tector C., Turner R., Venter E., Wang A.H., Wang X., Wang Z.-Y., Wassarman D.A., Weinstock G.M., Weissenbach J., Williams S.M., Woodage T., Worley K.C., Wu D., Yang S., Yao Q.A., Ye J., Yeh R.-F., Zaveri J.S., Zhan M., Zhang G., Zhao Q., Zheng L., Zheng X.H., Zhong F.N., Zhong W., Zhou X., Zhu S.C., Zhu X., Smith H.O., Gibbs R.A., Myers E.W., Rubin G.M., Venter J.C.
      Science 287:2185-2195(2000) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: Berkeley.
    4. Cited for: GENOME REANNOTATION, ALTERNATIVE SPLICING.
      Strain: Berkeley.
    5. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: Oregon-R.
    6. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM CYTOPLASMIC).
      Strain: Berkeley.
      Tissue: Embryo.
    7. "Phosphorylation of the Drosophila adherens junction protein Armadillo: roles for wingless signal and zeste-white 3 kinase."
      Peifer M., Pai L.-M., Casey M.
      Dev. Biol. 166:543-556(1994) [PubMed] [Europe PMC] [Abstract]
      Cited for: PHOSPHORYLATION.
    8. "Distinct cellular and subcellular patterns of expression imply distinct functions for the Drosophila homologues of moesin and the neurofibromatosis 2 tumor suppressor, merlin."
      McCartney B.M., Fehon R.G.
      J. Cell Biol. 133:843-852(1996) [PubMed] [Europe PMC] [Abstract]
      Cited for: INTERACTION WITH MER AND MOE, SUBCELLULAR LOCATION.
      Strain: Oregon-R.
      Tissue: Embryo.
    9. "Gap junction channel protein innexin 2 is essential for epithelial morphogenesis in the Drosophila embryo."
      Bauer R., Lehmann C., Martini J., Eckardt F., Hoch M.
      Mol. Biol. Cell 15:2992-3004(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: INTERACTION WITH INX2.
    10. "Phosphoproteome analysis of Drosophila melanogaster embryos."
      Zhai B., Villen J., Beausoleil S.A., Mintseris J., Gygi S.P.
      J. Proteome Res. 7:1675-1682(2008) [PubMed] [Europe PMC] [Abstract]
      Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-650; SER-688 AND SER-694, IDENTIFICATION BY MASS SPECTROMETRY.
      Tissue: Embryo.

    Entry informationi

    Entry nameiARM_DROME
    AccessioniPrimary (citable) accession number: P18824
    Secondary accession number(s): A4V3V0
    , O02371, Q0KHX2, Q8IRW7, Q9W546
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: November 1, 1990
    Last sequence update: November 1, 1990
    Last modified: October 1, 2014
    This is version 167 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programDrosophila annotation project

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Drosophila
      Drosophila: entries, gene names and cross-references to FlyBase
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3