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P18824

- ARM_DROME

UniProt

P18824 - ARM_DROME

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Protein

Armadillo segment polarity protein

Gene

arm

Organism
Drosophila melanogaster (Fruit fly)
Status
Reviewed - Annotation score: 5 out of 5- Experimental evidence at protein leveli

Functioni

Isoform neural may associate with CadN and participate in the transmission of developmental information. Can associate with alpha-catenin. Isoform cytoplasmic accumulates through wg signaling; arm function in wg signal transduction is required early in development for determination of neuroblast fate. Arm and Abl proteins function cooperatively at adherens junctions in both the CNS and epidermis.1 Publication

GO - Molecular functioni

  1. alpha-catenin binding Source: RefGenome
  2. cadherin binding Source: RefGenome
  3. cytoskeletal protein binding Source: FlyBase
  4. kinase binding Source: FlyBase
  5. protein complex binding Source: FlyBase
  6. protein kinase binding Source: RefGenome
  7. structural molecule activity Source: RefGenome
  8. transcription coactivator activity Source: FlyBase
  9. transcription factor binding Source: UniProtKB

GO - Biological processi

  1. branch fusion, open tracheal system Source: FlyBase
  2. branching morphogenesis of an epithelial tube Source: FlyBase
  3. cell adhesion Source: FlyBase
  4. cell fate determination Source: FlyBase
  5. cell morphogenesis Source: FlyBase
  6. chitin-based larval cuticle pattern formation Source: FlyBase
  7. compound eye morphogenesis Source: FlyBase
  8. compound eye retinal cell programmed cell death Source: FlyBase
  9. cuticle pattern formation Source: FlyBase
  10. cytoskeletal anchoring at plasma membrane Source: RefGenome
  11. delamination Source: FlyBase
  12. dorsal closure Source: FlyBase
  13. epithelial cell type specification, open tracheal system Source: FlyBase
  14. establishment or maintenance of cell polarity Source: FlyBase
  15. heart development Source: FlyBase
  16. heart formation Source: FlyBase
  17. imaginal disc-derived wing expansion Source: FlyBase
  18. long-term memory Source: FlyBase
  19. negative regulation of heart induction by canonical Wnt signaling pathway Source: FlyBase
  20. negative regulation of transcription from RNA polymerase II promoter Source: RefGenome
  21. nervous system development Source: FlyBase
  22. neuroblast development Source: FlyBase
  23. neuroblast fate commitment Source: UniProtKB
  24. oocyte development Source: RefGenome
  25. oocyte localization involved in germarium-derived egg chamber formation Source: FlyBase
  26. oogenesis Source: FlyBase
  27. ovarian follicle cell development Source: FlyBase
  28. photoreceptor cell differentiation Source: FlyBase
  29. positive regulation of transcription, DNA-templated Source: FlyBase
  30. positive regulation of transcription from RNA polymerase II promoter Source: FlyBase
  31. protein localization to adherens junction Source: FlyBase
  32. protein localization to plasma membrane Source: FlyBase
  33. regulation of cell shape Source: FlyBase
  34. segment polarity determination Source: UniProtKB-KW
  35. single organismal cell-cell adhesion Source: FlyBase
  36. somatic stem cell maintenance Source: FlyBase
  37. ventral furrow formation Source: FlyBase
  38. wing disc morphogenesis Source: FlyBase
  39. Wnt signaling pathway Source: FlyBase
  40. zonula adherens assembly Source: FlyBase
Complete GO annotation...

Keywords - Molecular functioni

Developmental protein, Segmentation polarity protein

Keywords - Biological processi

Cell adhesion, Wnt signaling pathway

Enzyme and pathway databases

ReactomeiREACT_184321. Ca2+ pathway.
REACT_184323. LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production.
REACT_207070. TCF dependent signaling in response to WNT.
REACT_218447. formation of the beta-catenin:TCF transactivating complex.
REACT_220429. disassembly of the destruction complex and recruitment of AXIN to the membrane.
SignaLinkiP18824.

Names & Taxonomyi

Protein namesi
Recommended name:
Armadillo segment polarity protein
Gene namesi
Name:arm
ORF Names:CG11579
OrganismiDrosophila melanogaster (Fruit fly)
Taxonomic identifieri7227 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
ProteomesiUP000000803: Chromosome X

Organism-specific databases

FlyBaseiFBgn0000117. arm.

Subcellular locationi

Cytoplasm 1 Publication. Cell membrane 1 Publication; Peripheral membrane protein 1 Publication; Cytoplasmic side 1 Publication. Cell junctionadherens junction By similarity
Note: Inner surface of cell membrane and adherens junction.

GO - Cellular componenti

  1. adherens junction Source: UniProtKB
  2. apical plasma membrane Source: FlyBase
  3. apicolateral plasma membrane Source: FlyBase
  4. axon Source: FlyBase
  5. basolateral plasma membrane Source: RefGenome
  6. catenin complex Source: FlyBase
  7. cytoplasm Source: FlyBase
  8. cytoplasmic side of plasma membrane Source: RefGenome
  9. cytosol Source: RefGenome
  10. desmosome Source: RefGenome
  11. endocytic vesicle Source: FlyBase
  12. fascia adherens Source: RefGenome
  13. nucleus Source: FlyBase
  14. plasma membrane Source: FlyBase
  15. spot adherens junction Source: FlyBase
  16. transcription factor complex Source: RefGenome
  17. Z disc Source: RefGenome
  18. zonula adherens Source: FlyBase
Complete GO annotation...

Keywords - Cellular componenti

Cell junction, Cell membrane, Cytoplasm, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 843843Armadillo segment polarity proteinPRO_0000064292Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei650 – 6501Phosphothreonine1 Publication
Modified residuei688 – 6881Phosphoserine1 Publication
Modified residuei694 – 6941Phosphoserine1 Publication

Post-translational modificationi

Phosphorylated on Ser, Thr and Tyr residues. Level of phosphorylation varies both during embryonic development and from embryonic tissue to tissue. Sgg is required for phosphorylation and wg signal negatively regulates arm phosphorylation. Hypophosphorylated form of arm increases in steady-state levels.2 Publications

Keywords - PTMi

Phosphoprotein

Proteomic databases

PaxDbiP18824.
PRIDEiP18824.

Expressioni

Tissue specificityi

Isoform cytoplasmic accumulates at low levels in axons, at high levels in specific cells along the CNS midline and in leg and eye imaginal disks. Isoform neural accumulates in the axon tracts of the CNS. Both isoforms accumulate in the peripheral nervous system.1 Publication

Developmental stagei

Present at all stages, but reaches the highest levels during early to mid-embryogenesis. Isoform cytoplasmic is the predominant one from the cellular blastoderm stage until germ-band retraction. Isoform neural is first seen after germ band retraction.

Gene expression databases

BgeeiP18824.

Interactioni

Subunit structurei

Interacts with Mer and Moe at the adherens junction. Interacts with Inx2.2 Publications

Binary interactionsi

WithEntry#Exp.IntActNotes
BCL9O005123EBI-216128,EBI-533127From a different organism.
ebd1Q9W0N93EBI-216128,EBI-141287
IswiQ243682EBI-216128,EBI-367628
lgsQ961D95EBI-216128,EBI-85519
nejO013683EBI-216128,EBI-868028
panP919432EBI-216128,EBI-147301

Protein-protein interaction databases

BioGridi57697. 71 interactions.
DIPiDIP-19968N.
IntActiP18824. 14 interactions.
MINTiMINT-344131.

Structurei

3D structure databases

ProteinModelPortaliP18824.
SMRiP18824. Positions 78-678.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Repeati159 – 20042ARM 1Add
BLAST
Repeati201 – 24242ARM 2Add
BLAST
Repeati243 – 28442ARM 3Add
BLAST
Repeati285 – 32642ARM 4Add
BLAST
Repeati327 – 36842ARM 5Add
BLAST
Repeati369 – 41042ARM 6Add
BLAST
Repeati411 – 44939ARM 7Add
BLAST
Repeati450 – 49647ARM 8Add
BLAST
Repeati497 – 53842ARM 9Add
BLAST
Repeati539 – 58446ARM 10Add
BLAST
Repeati585 – 60824ARM 11Add
BLAST
Repeati609 – 64739ARM 12Add
BLAST
Repeati648 – 68942ARM 13; truncatedAdd
BLAST

Compositional bias

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Compositional biasi1 – 158158Asp/Glu-rich (acidic)Add
BLAST
Compositional biasi690 – 843154Asp/Glu-rich (acidic)Add
BLAST

Sequence similaritiesi

Belongs to the beta-catenin family.Curated
Contains 13 ARM repeats.PROSITE-ProRule annotation

Keywords - Domaini

Repeat

Phylogenomic databases

eggNOGiNOG297695.
GeneTreeiENSGT00730000110821.
InParanoidiP18824.
KOiK02105.
OMAiRESHNRA.
OrthoDBiEOG7X9G6B.
PhylomeDBiP18824.

Family and domain databases

Gene3Di1.25.10.10. 1 hit.
InterProiIPR011989. ARM-like.
IPR016024. ARM-type_fold.
IPR000225. Armadillo.
IPR013284. Beta-catenin.
[Graphical view]
PfamiPF00514. Arm. 4 hits.
[Graphical view]
PRINTSiPR01869. BCATNINFAMLY.
SMARTiSM00185. ARM. 12 hits.
[Graphical view]
SUPFAMiSSF48371. SSF48371. 1 hit.
PROSITEiPS50176. ARM_REPEAT. 9 hits.
[Graphical view]

Sequences (2)i

Sequence statusi: Complete.

This entry describes 2 isoformsi produced by alternative splicing. Align

Isoform Cytoplasmic (identifier: P18824-1) [UniParc]FASTAAdd to Basket

Also known as: A, B

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MSYMPAQNRT MSHNNQYNPP DLPPMVSAKE QTLMWQQNSY LGDSGIHSGA
60 70 80 90 100
VTQVPSLSGK EDEEMEGDPL MFDLDTGFPQ NFTQDQVDDM NQQLSQTRSQ
110 120 130 140 150
RVRAAMFPET LEEGIEIPST QFDPQQPTAV QRLSEPSQML KHAVVNLINY
160 170 180 190 200
QDDAELATRA IPELIKLLND EDQVVVSQAA MMVHQLSKKE ASRHAIMNSP
210 220 230 240 250
QMVAALVRAI SNSNDLESTK AAVGTLHNLS HHRQGLLAIF KSGGIPALVK
260 270 280 290 300
LLSSPVESVL FYAITTLHNL LLHQDGSKMA VRLAGGLQKM VTLLQRNNVK
310 320 330 340 350
FLAIVTDCLQ ILAYGNQESK LIILASGGPN ELVRIMRSYD YEKLLWTTSR
360 370 380 390 400
VLKVLSVCSS NKPAIVDAGG MQALAMHLGN MSPRLVQNCL WTLRNLSDAA
410 420 430 440 450
TKVEGLEALL QSLVQVLGST DVNVVTCAAG ILSNLTCNNQ RNKATVCQVG
460 470 480 490 500
GVDALVRTII NAGDREEITE PAVCALRHLT SRHVDSELAQ NAVRLNYGLS
510 520 530 540 550
VIVKLLHPPS RWPLIKAVIG LIRNLALCPA NHAPLREHGA IHHLVRLLMR
560 570 580 590 600
AFQDTERQRS SIATTGSQQP SAYADGVRME EIVEGTVGAL HILARESHNR
610 620 630 640 650
ALIRQQSVIP IFVRLLFNEI ENIQRVAAGV LCELAADKEG AEIIEQEGAT
660 670 680 690 700
GPLTDLLHSR NEGVATYAAA VLFRMSEDKP QDYKKRLSIE LTNSLLREDN
710 720 730 740 750
NIWANADLGM GPDLQDMLGP EEAYEGLYGQ GPPSVHSSHG GRAFHQQGYD
760 770 780 790 800
TLPIDSMQGL EISSPVGGGG AGGAPGNGGA VGGASGGGGN IGAIPPSGAP
810 820 830 840
TSPYSMDMDV GEIDAGALNF DLDAMPTPPN DNNNLAAWYD TDC
Length:843
Mass (Da):91,153
Last modified:November 1, 1990 - v1
Checksum:i40DAD6FB83163049
GO
Isoform Neural (identifier: P18824-2) [UniParc]FASTAAdd to Basket

Also known as: C

The sequence of this isoform differs from the canonical sequence as follows:
     718-843: LGPEEAYEGL...NLAAWYDTDC → ILYQ

Show »
Length:721
Mass (Da):79,314
Checksum:i0E19594766E0847F
GO

Alternative sequence

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Alternative sequencei718 – 843126LGPEE…YDTDC → ILYQ in isoform Neural. 1 PublicationVSP_006738Add
BLAST

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
X54468 Genomic DNA. Translation: CAA38350.1.
AF001213 mRNA. Translation: AAB58731.1.
AE014298 Genomic DNA. Translation: AAF45686.2.
AE014298 Genomic DNA. Translation: AAF45687.2.
AE014298 Genomic DNA. Translation: AAN09064.2.
AE014298 Genomic DNA. Translation: AAS65246.1.
AL021106, AL021086 Genomic DNA. Translation: CAA15946.1.
AL021086, AL021106 Genomic DNA. Translation: CAA15935.1.
AY118525 mRNA. Translation: AAM49894.1.
PIRiT12689.
RefSeqiNP_001259149.1. NM_001272220.1. [P18824-1]
NP_476665.2. NM_057317.4. [P18824-1]
NP_476666.1. NM_057318.4. [P18824-1]
NP_599100.1. NM_134273.2. [P18824-1]
NP_726775.2. NM_166912.2. [P18824-2]
NP_996328.1. NM_206605.2. [P18824-1]
UniGeneiDm.4782.

Genome annotation databases

EnsemblMetazoaiFBtr0089988; FBpp0089031; FBgn0000117. [P18824-1]
FBtr0089989; FBpp0089032; FBgn0000117. [P18824-1]
FBtr0089991; FBpp0089034; FBgn0000117. [P18824-1]
FBtr0089992; FBpp0089035; FBgn0000117. [P18824-1]
FBtr0332583; FBpp0304835; FBgn0000117. [P18824-1]
GeneIDi31151.
KEGGidme:Dmel_CG11579.

Keywords - Coding sequence diversityi

Alternative splicing

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
X54468 Genomic DNA. Translation: CAA38350.1 .
AF001213 mRNA. Translation: AAB58731.1 .
AE014298 Genomic DNA. Translation: AAF45686.2 .
AE014298 Genomic DNA. Translation: AAF45687.2 .
AE014298 Genomic DNA. Translation: AAN09064.2 .
AE014298 Genomic DNA. Translation: AAS65246.1 .
AL021106 , AL021086 Genomic DNA. Translation: CAA15946.1 .
AL021086 , AL021106 Genomic DNA. Translation: CAA15935.1 .
AY118525 mRNA. Translation: AAM49894.1 .
PIRi T12689.
RefSeqi NP_001259149.1. NM_001272220.1. [P18824-1 ]
NP_476665.2. NM_057317.4. [P18824-1 ]
NP_476666.1. NM_057318.4. [P18824-1 ]
NP_599100.1. NM_134273.2. [P18824-1 ]
NP_726775.2. NM_166912.2. [P18824-2 ]
NP_996328.1. NM_206605.2. [P18824-1 ]
UniGenei Dm.4782.

3D structure databases

ProteinModelPortali P18824.
SMRi P18824. Positions 78-678.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

BioGridi 57697. 71 interactions.
DIPi DIP-19968N.
IntActi P18824. 14 interactions.
MINTi MINT-344131.

Proteomic databases

PaxDbi P18824.
PRIDEi P18824.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblMetazoai FBtr0089988 ; FBpp0089031 ; FBgn0000117 . [P18824-1 ]
FBtr0089989 ; FBpp0089032 ; FBgn0000117 . [P18824-1 ]
FBtr0089991 ; FBpp0089034 ; FBgn0000117 . [P18824-1 ]
FBtr0089992 ; FBpp0089035 ; FBgn0000117 . [P18824-1 ]
FBtr0332583 ; FBpp0304835 ; FBgn0000117 . [P18824-1 ]
GeneIDi 31151.
KEGGi dme:Dmel_CG11579.

Organism-specific databases

CTDi 31151.
FlyBasei FBgn0000117. arm.

Phylogenomic databases

eggNOGi NOG297695.
GeneTreei ENSGT00730000110821.
InParanoidi P18824.
KOi K02105.
OMAi RESHNRA.
OrthoDBi EOG7X9G6B.
PhylomeDBi P18824.

Enzyme and pathway databases

Reactomei REACT_184321. Ca2+ pathway.
REACT_184323. LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production.
REACT_207070. TCF dependent signaling in response to WNT.
REACT_218447. formation of the beta-catenin:TCF transactivating complex.
REACT_220429. disassembly of the destruction complex and recruitment of AXIN to the membrane.
SignaLinki P18824.

Miscellaneous databases

ChiTaRSi arm. drosophila.
GenomeRNAii 31151.
NextBioi 772169.
PROi P18824.

Gene expression databases

Bgeei P18824.

Family and domain databases

Gene3Di 1.25.10.10. 1 hit.
InterProi IPR011989. ARM-like.
IPR016024. ARM-type_fold.
IPR000225. Armadillo.
IPR013284. Beta-catenin.
[Graphical view ]
Pfami PF00514. Arm. 4 hits.
[Graphical view ]
PRINTSi PR01869. BCATNINFAMLY.
SMARTi SM00185. ARM. 12 hits.
[Graphical view ]
SUPFAMi SSF48371. SSF48371. 1 hit.
PROSITEi PS50176. ARM_REPEAT. 9 hits.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Molecular analysis of the armadillo locus: uniformly distributed transcripts and a protein with novel internal repeats are associated with a Drosophila segment polarity gene."
    Riggleman B., Wieschaus E., Schedl P.
    Genes Dev. 3:96-113(1989) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: Oregon-R.
    Tissue: Embryo.
  2. "Roles of Armadillo, a Drosophila catenin, during central nervous system development."
    Loureiro J., Peifer M.
    Curr. Biol. 8:622-632(1998) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS CYTOPLASMIC AND NEURAL), FUNCTION, TISSUE SPECIFICITY.
    Tissue: Head.
  3. "The genome sequence of Drosophila melanogaster."
    Adams M.D., Celniker S.E., Holt R.A., Evans C.A., Gocayne J.D., Amanatides P.G., Scherer S.E., Li P.W., Hoskins R.A., Galle R.F., George R.A., Lewis S.E., Richards S., Ashburner M., Henderson S.N., Sutton G.G., Wortman J.R., Yandell M.D.
    , Zhang Q., Chen L.X., Brandon R.C., Rogers Y.-H.C., Blazej R.G., Champe M., Pfeiffer B.D., Wan K.H., Doyle C., Baxter E.G., Helt G., Nelson C.R., Miklos G.L.G., Abril J.F., Agbayani A., An H.-J., Andrews-Pfannkoch C., Baldwin D., Ballew R.M., Basu A., Baxendale J., Bayraktaroglu L., Beasley E.M., Beeson K.Y., Benos P.V., Berman B.P., Bhandari D., Bolshakov S., Borkova D., Botchan M.R., Bouck J., Brokstein P., Brottier P., Burtis K.C., Busam D.A., Butler H., Cadieu E., Center A., Chandra I., Cherry J.M., Cawley S., Dahlke C., Davenport L.B., Davies P., de Pablos B., Delcher A., Deng Z., Mays A.D., Dew I., Dietz S.M., Dodson K., Doup L.E., Downes M., Dugan-Rocha S., Dunkov B.C., Dunn P., Durbin K.J., Evangelista C.C., Ferraz C., Ferriera S., Fleischmann W., Fosler C., Gabrielian A.E., Garg N.S., Gelbart W.M., Glasser K., Glodek A., Gong F., Gorrell J.H., Gu Z., Guan P., Harris M., Harris N.L., Harvey D.A., Heiman T.J., Hernandez J.R., Houck J., Hostin D., Houston K.A., Howland T.J., Wei M.-H., Ibegwam C., Jalali M., Kalush F., Karpen G.H., Ke Z., Kennison J.A., Ketchum K.A., Kimmel B.E., Kodira C.D., Kraft C.L., Kravitz S., Kulp D., Lai Z., Lasko P., Lei Y., Levitsky A.A., Li J.H., Li Z., Liang Y., Lin X., Liu X., Mattei B., McIntosh T.C., McLeod M.P., McPherson D., Merkulov G., Milshina N.V., Mobarry C., Morris J., Moshrefi A., Mount S.M., Moy M., Murphy B., Murphy L., Muzny D.M., Nelson D.L., Nelson D.R., Nelson K.A., Nixon K., Nusskern D.R., Pacleb J.M., Palazzolo M., Pittman G.S., Pan S., Pollard J., Puri V., Reese M.G., Reinert K., Remington K., Saunders R.D.C., Scheeler F., Shen H., Shue B.C., Siden-Kiamos I., Simpson M., Skupski M.P., Smith T.J., Spier E., Spradling A.C., Stapleton M., Strong R., Sun E., Svirskas R., Tector C., Turner R., Venter E., Wang A.H., Wang X., Wang Z.-Y., Wassarman D.A., Weinstock G.M., Weissenbach J., Williams S.M., Woodage T., Worley K.C., Wu D., Yang S., Yao Q.A., Ye J., Yeh R.-F., Zaveri J.S., Zhan M., Zhang G., Zhao Q., Zheng L., Zheng X.H., Zhong F.N., Zhong W., Zhou X., Zhu S.C., Zhu X., Smith H.O., Gibbs R.A., Myers E.W., Rubin G.M., Venter J.C.
    Science 287:2185-2195(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Berkeley.
  4. Cited for: GENOME REANNOTATION, ALTERNATIVE SPLICING.
    Strain: Berkeley.
  5. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Oregon-R.
  6. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM CYTOPLASMIC).
    Strain: Berkeley.
    Tissue: Embryo.
  7. "Phosphorylation of the Drosophila adherens junction protein Armadillo: roles for wingless signal and zeste-white 3 kinase."
    Peifer M., Pai L.-M., Casey M.
    Dev. Biol. 166:543-556(1994) [PubMed] [Europe PMC] [Abstract]
    Cited for: PHOSPHORYLATION.
  8. "Distinct cellular and subcellular patterns of expression imply distinct functions for the Drosophila homologues of moesin and the neurofibromatosis 2 tumor suppressor, merlin."
    McCartney B.M., Fehon R.G.
    J. Cell Biol. 133:843-852(1996) [PubMed] [Europe PMC] [Abstract]
    Cited for: INTERACTION WITH MER AND MOE, SUBCELLULAR LOCATION.
    Strain: Oregon-R.
    Tissue: Embryo.
  9. "Gap junction channel protein innexin 2 is essential for epithelial morphogenesis in the Drosophila embryo."
    Bauer R., Lehmann C., Martini J., Eckardt F., Hoch M.
    Mol. Biol. Cell 15:2992-3004(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: INTERACTION WITH INX2.
  10. "Phosphoproteome analysis of Drosophila melanogaster embryos."
    Zhai B., Villen J., Beausoleil S.A., Mintseris J., Gygi S.P.
    J. Proteome Res. 7:1675-1682(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-650; SER-688 AND SER-694, IDENTIFICATION BY MASS SPECTROMETRY.
    Tissue: Embryo.

Entry informationi

Entry nameiARM_DROME
AccessioniPrimary (citable) accession number: P18824
Secondary accession number(s): A4V3V0
, O02371, Q0KHX2, Q8IRW7, Q9W546
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1990
Last sequence update: November 1, 1990
Last modified: October 29, 2014
This is version 168 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programDrosophila annotation project

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Drosophila
    Drosophila: entries, gene names and cross-references to FlyBase
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3