Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

P18797

- MMOB_METCA

UniProt

P18797 - MMOB_METCA

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Methane monooxygenase regulatory protein B

Gene

mmoB

Organism
Methylococcus capsulatus (strain ATCC 33009 / NCIMB 11132 / Bath)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at protein leveli

Functioni

The B protein acts as a regulator of electron flow through the soluble mmo complex, switching the enzyme from an oxidase to a hydroxylase in the presence of the substrate.

GO - Molecular functioni

  1. monooxygenase activity Source: UniProtKB-KW

GO - Biological processi

  1. cellular aromatic compound metabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Monooxygenase, Oxidoreductase

Enzyme and pathway databases

BioCyciMetaCyc:MONOMER-3865.

Names & Taxonomyi

Protein namesi
Recommended name:
Methane monooxygenase regulatory protein B
Gene namesi
Name:mmoB
Ordered Locus Names:MCA1196
OrganismiMethylococcus capsulatus (strain ATCC 33009 / NCIMB 11132 / Bath)
Taxonomic identifieri243233 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaMethylococcalesMethylococcaceaeMethylococcus
ProteomesiUP000006821: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 141141Methane monooxygenase regulatory protein BPRO_0000096507Add
BLAST

Interactioni

Subunit structurei

The soluble methane monooxygenase (sMMO) consists of four components A/MMOH (composed of alpha/MmoX, beta/MmoY and gamma/MmoZ), B/MMOB (MmoB), C/MMOR (MmoC) and D/MMOD (MmoD).

Protein-protein interaction databases

DIPiDIP-60130N.
STRINGi243233.MCA1196.

Structurei

Secondary structure

1
141
Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Beta strandi4 – 74Combined sources
Turni11 – 144Combined sources
Helixi18 – 258Combined sources
Helixi28 – 303Combined sources
Beta strandi37 – 437Combined sources
Helixi46 – 549Combined sources
Turni55 – 584Combined sources
Helixi59 – 635Combined sources
Beta strandi69 – 724Combined sources
Beta strandi74 – 8815Combined sources
Helixi89 – 968Combined sources
Helixi102 – 1054Combined sources
Beta strandi108 – 12821Combined sources
Turni130 – 1323Combined sources

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1CKVNMR-A1-141[»]
4GAMX-ray2.90D/I/N/S1-141[»]
ProteinModelPortaliP18797.
SMRiP18797. Positions 1-141.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP18797.

Family & Domainsi

Phylogenomic databases

eggNOGiNOG249775.
HOGENOMiHOG000086316.
KOiK16160.
OMAiSTIGRAY.
OrthoDBiEOG6J48RG.

Family and domain databases

Gene3Di3.90.56.10. 1 hit.
InterProiIPR003454. mOase_MmoB_DmpM.
[Graphical view]
PfamiPF02406. MmoB_DmpM. 1 hit.
[Graphical view]
SUPFAMiSSF56029. SSF56029. 1 hit.

Sequencei

Sequence statusi: Complete.

P18797-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MSVNSNAYDA GIMGLKGKDF ADQFFADENQ VVHESDTVVL VLKKSDEINT
60 70 80 90 100
FIEEILLTDY KKNVNPTVNV EDRAGYWWIK ANGKIEVDCD EISELLGRQF
110 120 130 140
NVYDFLVDVS STIGRAYTLG NKFTITSELM GLDRKLEDYH A
Length:141
Mass (Da):15,984
Last modified:December 7, 2004 - v2
Checksum:i86A1496846C5840F
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti12 – 121I → F(PubMed:2505721)Curated
Sequence conflicti12 – 121I → F1 PublicationCurated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M90050 Genomic DNA. Translation: AAF04158.2.
AE017282 Genomic DNA. Translation: AAU92726.1.
PIRiJL0103.
RefSeqiWP_010960484.1. NC_002977.6.
YP_113661.1. NC_002977.6.

Genome annotation databases

EnsemblBacteriaiAAU92726; AAU92726; MCA1196.
GeneIDi3103283.
KEGGimca:MCA1196.
PATRICi22606224. VBIMetCap22254_1228.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M90050 Genomic DNA. Translation: AAF04158.2 .
AE017282 Genomic DNA. Translation: AAU92726.1 .
PIRi JL0103.
RefSeqi WP_010960484.1. NC_002977.6.
YP_113661.1. NC_002977.6.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
Entry Method Resolution (Å) Chain Positions PDBsum
1CKV NMR - A 1-141 [» ]
4GAM X-ray 2.90 D/I/N/S 1-141 [» ]
ProteinModelPortali P18797.
SMRi P18797. Positions 1-141.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

DIPi DIP-60130N.
STRINGi 243233.MCA1196.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAU92726 ; AAU92726 ; MCA1196 .
GeneIDi 3103283.
KEGGi mca:MCA1196.
PATRICi 22606224. VBIMetCap22254_1228.

Phylogenomic databases

eggNOGi NOG249775.
HOGENOMi HOG000086316.
KOi K16160.
OMAi STIGRAY.
OrthoDBi EOG6J48RG.

Enzyme and pathway databases

BioCyci MetaCyc:MONOMER-3865.

Miscellaneous databases

EvolutionaryTracei P18797.

Family and domain databases

Gene3Di 3.90.56.10. 1 hit.
InterProi IPR003454. mOase_MmoB_DmpM.
[Graphical view ]
Pfami PF02406. MmoB_DmpM. 1 hit.
[Graphical view ]
SUPFAMi SSF56029. SSF56029. 1 hit.
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Molecular analysis of methane monooxygenase from Methylococcus capsulatus (Bath)."
    Stainthorpe A.C., Murrell J.C., Salmond G.P.C., Dalton H., Lees V.
    Arch. Microbiol. 152:154-159(1989) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: ATCC 33009 / NCIMB 11132 / Bath.
  2. McDonald I., Murrell J.C.
    Submitted (OCT-1999) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
  3. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 33009 / NCIMB 11132 / Bath.
  4. "Identification of the gene encoding the regulatory protein B of soluble methane monooxygenase."
    Pilkington S.J., Salmond G.P.C., Murrell J.C., Dalton H.
    FEMS Microbiol. Lett. 72:345-348(1990)
    Cited for: IDENTIFICATION OF PROTEIN, PROTEIN SEQUENCE OF 3-19.
  5. "Structure of the soluble methane monooxygenase regulatory protein B."
    Walters K.J., Gassner G.T., Lippard S.J., Wagner G.
    Proc. Natl. Acad. Sci. U.S.A. 96:7877-7882(1999) [PubMed] [Europe PMC] [Abstract]
    Cited for: STRUCTURE BY NMR.
  6. "Mutational and structural analyses of the regulatory protein B of soluble methane monooxygenase from Methylococcus capsulatus (Bath)."
    Brandstetter H., Whittington D.A., Lippard S.J., Frederick C.A.
    Chem. Biol. 6:441-449(1999) [PubMed] [Europe PMC] [Abstract]
    Cited for: CIRCULAR DICHROISM ANALYSIS, 3D-STRUCTURE MODELING.

Entry informationi

Entry nameiMMOB_METCA
AccessioniPrimary (citable) accession number: P18797
Secondary accession number(s): Q609N6, Q9LCT7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1990
Last sequence update: December 7, 2004
Last modified: November 26, 2014
This is version 90 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references

External Data

Dasty 3