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Protein

Arrestin-related trafficking adapter 10

Gene

ART10

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

May regulate endocytosis by recruiting RSP5 ubiquitin ligase activity to specific plasma membrane proteins in response to extracellular stimuli.By similarity

Miscellaneous

Present with 736 molecules/cell in log phase SD medium.1 Publication

GO - Biological processi

Keywordsi

Biological processEndocytosis

Enzyme and pathway databases

BioCyciYEAST:G3O-32457-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Arrestin-related trafficking adapter 10
Gene namesi
Name:ART10
Ordered Locus Names:YLR392C
ORF Names:L8084.13
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
Proteomesi
  • UP000002311 Componenti: Chromosome XII

Organism-specific databases

EuPathDBiFungiDB:YLR392C
SGDiS000004384 ART10

Subcellular locationi

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002032351 – 518Arrestin-related trafficking adapter 10Add BLAST518

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Cross-linki118Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin)Combined sources

Post-translational modificationi

Ubiquitinated by RSP5.1 Publication

Keywords - PTMi

Isopeptide bond, Ubl conjugation

Proteomic databases

MaxQBiP18634
PaxDbiP18634
PRIDEiP18634

PTM databases

iPTMnetiP18634

Interactioni

Subunit structurei

Interacts with RSP5.1 Publication

Binary interactionsi

WithEntry#Exp.IntActNotes
RSP5P399405EBI-27197,EBI-16219

Protein-protein interaction databases

BioGridi31651, 31 interactors
DIPiDIP-1946N
IntActiP18634, 2 interactors
MINTiP18634
STRINGi4932.YLR392C

Structurei

3D structure databases

ProteinModelPortaliP18634
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the ART10 family.Curated

Phylogenomic databases

InParanoidiP18634
OMAiNEEDYRH
OrthoDBiEOG092C1MBA

Family and domain databases

Gene3Di2.60.40.640, 1 hit
InterProiView protein in InterPro
IPR014752 Arrestin_C

Sequencei

Sequence statusi: Complete.

P18634-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAPKISISLN PPYNGEFYSS NDQMSGIVSL QLTKALSIRK ISVILKGFSE
60 70 80 90 100
TLTKIDQEYM FQQNGMMMPG QDNKSFHTLM KFEQRVFPPD NVWNALDGSS
110 120 130 140 150
KPFKVKPGSY NYSFQFDKFP RKPECLKNHT AKTVAFVTRS NARLPPTFNS
160 170 180 190 200
HWQEFNKIDN LDLYFYSFGK VIYMVQVQLE LGKSSSWFKP FHKLIREIET
210 220 230 240 250
FEFIPEPKDL IIEPDEDDNE ELNAFSNNSR GNSMVTNNEF FNSSNLKVPS
260 270 280 290 300
KDVKVVNGVG YIKSDRNFSQ ANSILIENGD IRSRPVSSVT STRQSTRLVN
310 320 330 340 350
GMKVFPSTYK MGLPDGESNM RIEVRSRDLK QIYRKDYLFR SGSQNFDKVY
360 370 380 390 400
VVMEGNIASL SKMQITPLKL QLNLLETTTY LSQGIANGNY SSLKLIEIDL
410 420 430 440 450
NQLKSNKPLL DLNEIRENFD GSMFECELRL KDHPILRKLV FNEEDYRHRG
460 470 480 490 500
NRLYSFKTCT IKRTFSLQLL IEWGINGIRK QSEVNIDPVQ IFCQVREHVE
510
AEALPRYVPP PTYTEMAS
Length:518
Mass (Da):59,758
Last modified:November 1, 1997 - v3
Checksum:i65399EA2FFFC2C23
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U19729 Genomic DNA Translation: AAB82352.1
J05463 Genomic DNA Translation: AAB05631.1
BK006945 Genomic DNA Translation: DAA09693.1
PIRiS55948
RefSeqiNP_013496.3, NM_001182280.3

Genome annotation databases

EnsemblFungiiYLR392C; YLR392C; YLR392C
GeneIDi851108
KEGGisce:YLR392C

Similar proteinsi

Entry informationi

Entry nameiART10_YEAST
AccessioniPrimary (citable) accession number: P18634
Secondary accession number(s): D6VZ27
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1990
Last sequence update: November 1, 1997
Last modified: March 28, 2018
This is version 119 of the entry and version 3 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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