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P18597 (ATP4B_RABIT) Reviewed, UniProtKB/Swiss-Prot

Last modified November 16, 2011. Version 80. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Potassium-transporting ATPase subunit beta
Alternative name(s):
Gastric H(+)/K(+) ATPase subunit beta
Proton pump beta chain
Gene names
Name:ATP4B
OrganismOryctolagus cuniculus (Rabbit) [Complete proteome]
Taxonomic identifier9986 [NCBI]
Taxonomic lineageEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Lagomorpha › Leporidae › Oryctolagus

Protein attributes

Sequence length291 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Subunit structure

Composed of two subunits: alpha (catalytic) and beta.

Subcellular location

Membrane; Single-pass type II membrane protein.

Tissue specificity

Stomach.

Sequence similarities

Belongs to the X(+)/potassium ATPases subunit beta family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 291291Potassium-transporting ATPase subunit beta
PRO_0000219094

Regions

Topological domain1 – 3636Cytoplasmic Potential
Transmembrane37 – 5721Helical; Signal-anchor for type II membrane protein; Potential
Topological domain58 – 291234Extracellular Potential

Amino acid modifications

Glycosylation991N-linked (GlcNAc...) Potential
Glycosylation1031N-linked (GlcNAc...) Potential
Glycosylation1301N-linked (GlcNAc...) Potential
Glycosylation1461N-linked (GlcNAc...) Potential
Glycosylation1611N-linked (GlcNAc...) Potential
Glycosylation1931N-linked (GlcNAc...) Potential
Glycosylation2221N-linked (GlcNAc...) Potential
Disulfide bond131 ↔ 152 By similarity
Disulfide bond162 ↔ 178 By similarity
Disulfide bond201 ↔ 263 By similarity

Sequences

Sequence LengthMass (Da)Tools
P18597 [UniParc].

Last modified November 1, 1990. Version 1.
Checksum: 6D2FE467A36CC103

FASTA29133,419
        10         20         30         40         50         60 
MAALQEKKSC SQRMEEFRHY CWNPDTGQML GRTLSRWVWI SLYYVAFYVV MTGLFALCIY 

        70         80         90        100        110        120 
VLMQTIDPYT PDYQDQLKSP GVTLRPDVYG EKGLEIHYNI SDNRTWTSLT HTLRSFLAGY 

       130        140        150        160        170        180 
SPAAQVDNIN CTSKTYFFQE SFGAPNHTKF SCKFTADMLE NCSGLTDPSF GFKEGKPCFI 

       190        200        210        220        230        240 
IKMNRIVRFL PSNSTPPRVD CTFLDMPHQA LTPLQVEYYP PNGTFSLHYF PYYGKKAQPH 

       250        260        270        280        290 
YSNPLVAAKL LNVPTNTEVV VLCKILADHV TFDNPHDPYE GKVEFKLKIQ K

« Hide

References

[1]"Characterization of a beta subunit of the gastric H+/K(+)-transporting ATPase."
Reuben M.A., Lasater L.S., Sachs G.
Proc. Natl. Acad. Sci. U.S.A. 87:6767-6771(1990) [PubMed: 2168558] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [MRNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		M35544 mRNA. Translation: AAA31256.1.
PIRA36051.
RefSeqNP_001075758.1. NM_001082289.1.
UniGeneOcu.1881.

3D structure databases

ProteinModelPortalP18597.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID100009125.

Organism-specific databases

CTD496.

Phylogenomic databases

eggNOGmaNOG04119.
GeneTreeENSGT00550000074530.
HOVERGENHBG050603.
OrthoDBEOG4TXBS9.

Enzyme and pathway databases

BRENDA3.6.3.10. 1749.

Family and domain databases

InterProIPR000402. ATPase_P-typ_cation-exchng_bsu.
[Graphical view]
PANTHERPTHR11523. ATPase_H_Na/K_b. 1 hit.
PfamPF00287. Na_K-ATPase. 1 hit.
[Graphical view]
TIGRFAMsTIGR01107. Na_K_ATPase_bet. 1 hit.
PROSITEPS00390. ATPASE_NA_K_BETA_1. 1 hit.
PS00391. ATPASE_NA_K_BETA_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameATP4B_RABIT
AccessionPrimary (citable) accession number: P18597
Entry history
Integrated into UniProtKB/Swiss-Prot: November 1, 1990
Last sequence update: November 1, 1990
Last modified: November 16, 2011
This is version 80 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

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