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Protein

Ig heavy chain V region 1B43

Gene
N/A
Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Recommended name:
Ig heavy chain V region 1B43
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Unplaced

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 18Add BLAST18
ChainiPRO_000001524219 – 116Ig heavy chain V region 1B43Add BLAST98

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi40 ↔ 114PROSITE-ProRule annotation

Keywords - PTMi

Disulfide bond

Proteomic databases

PRIDEiP18532.

Structurei

Secondary structure

1116
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Beta strandi22 – 25Combined sources4
Beta strandi28 – 30Combined sources3
Beta strandi36 – 45Combined sources10
Turni47 – 49Combined sources3
Beta strandi50 – 58Combined sources9
Beta strandi64 – 71Combined sources8
Beta strandi76 – 78Combined sources3
Turni80 – 85Combined sources6
Beta strandi86 – 91Combined sources6
Turni92 – 95Combined sources4
Beta strandi96 – 101Combined sources6
Helixi106 – 108Combined sources3
Beta strandi110 – 116Combined sources7

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1KCSX-ray2.50H22-116[»]
1KCVX-ray1.80H22-116[»]
2EXPmodel-H19-114[»]
2EXQmodel-H19-114[»]
2F58X-ray2.80H19-116[»]
3F58X-ray2.80H19-116[»]
ProteinModelPortaliP18532.
SMRiP18532.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP18532.

Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni19 – 48Framework-1Add BLAST30
Regioni49 – 53Complementarity-determining-15
Regioni54 – 67Framework-2Add BLAST14
Regioni68 – 84Complementarity-determining-2Add BLAST17
Regioni85 – 116Framework-3Add BLAST32

Keywords - Domaini

Immunoglobulin domain, Immunoglobulin V region, Signal

Phylogenomic databases

HOVERGENiHBG018013.

Family and domain databases

Gene3Di2.60.40.10. 1 hit.
InterProiIPR007110. Ig-like_dom.
IPR013783. Ig-like_fold.
IPR013106. Ig_V-set.
[Graphical view]
PfamiPF07686. V-set. 1 hit.
[Graphical view]
SMARTiSM00406. IGv. 1 hit.
[Graphical view]
SUPFAMiSSF48726. SSF48726. 1 hit.
PROSITEiPS50835. IG_LIKE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P18532-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRVLILLCLF TAFPGILSDV QLQESGPDLV KPSQSLSLTC TVTGYSITSG
60 70 80 90 100
YSWHWIRQFP GNKLEWMGYI HYSGNTSYNP SLKSRISITR DTSKNQFFLQ
110
LNSVTTEDTA TYYCAR
Length:116
Mass (Da):13,158
Last modified:November 1, 1990 - v1
Checksum:i1CB547253681FF74
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1161

Sequence databases

PIRiJT0508. HVMS1B.

Cross-referencesi

Sequence databases

PIRiJT0508. HVMS1B.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1KCSX-ray2.50H22-116[»]
1KCVX-ray1.80H22-116[»]
2EXPmodel-H19-114[»]
2EXQmodel-H19-114[»]
2F58X-ray2.80H19-116[»]
3F58X-ray2.80H19-116[»]
ProteinModelPortaliP18532.
SMRiP18532.
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PRIDEiP18532.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Phylogenomic databases

HOVERGENiHBG018013.

Miscellaneous databases

EvolutionaryTraceiP18532.

Family and domain databases

Gene3Di2.60.40.10. 1 hit.
InterProiIPR007110. Ig-like_dom.
IPR013783. Ig-like_fold.
IPR013106. Ig_V-set.
[Graphical view]
PfamiPF07686. V-set. 1 hit.
[Graphical view]
SMARTiSM00406. IGv. 1 hit.
[Graphical view]
SUPFAMiSSF48726. SSF48726. 1 hit.
PROSITEiPS50835. IG_LIKE. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiHVM61_MOUSE
AccessioniPrimary (citable) accession number: P18532
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1990
Last sequence update: November 1, 1990
Last modified: November 2, 2016
This is version 105 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Miscellaneous

This sequence belongs to the VH3660 subfamily.

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.