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Protein

Ig heavy chain V region 5-76

Gene
N/A
Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Recommended name:
Ig heavy chain V region 5-76
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Unplaced

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 19Add BLAST19
ChainiPRO_000001523920 – 117Ig heavy chain V region 5-76Add BLAST98

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi41 ↔ 115PROSITE-ProRule annotation

Keywords - PTMi

Disulfide bond

Proteomic databases

MaxQBiP18529.
PRIDEiP18529.

Structurei

Secondary structure

1117
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Beta strandi22 – 26Combined sources5
Beta strandi29 – 31Combined sources3
Beta strandi37 – 46Combined sources10
Helixi48 – 50Combined sources3
Beta strandi53 – 58Combined sources6
Beta strandi64 – 70Combined sources7
Beta strandi77 – 79Combined sources3
Turni81 – 86Combined sources6
Beta strandi87 – 92Combined sources6
Helixi93 – 95Combined sources3
Beta strandi97 – 102Combined sources6
Helixi107 – 109Combined sources3
Beta strandi111 – 117Combined sources7

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1BFVX-ray2.10H21-117[»]
1I8IX-ray2.40B21-117[»]
1I8KX-ray1.80B21-117[»]
ProteinModelPortaliP18529.
SMRiP18529.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP18529.

Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni20 – 49Framework-1Add BLAST30
Regioni50 – 54Complementarity-determining-15
Regioni55 – 68Framework-2Add BLAST14
Regioni69 – 85Complementarity-determining-2Add BLAST17
Regioni86 – 117Framework-3Add BLAST32

Keywords - Domaini

Immunoglobulin domain, Immunoglobulin V region, Signal

Phylogenomic databases

HOVERGENiHBG018013.

Family and domain databases

Gene3Di2.60.40.10. 1 hit.
InterProiIPR007110. Ig-like_dom.
IPR013783. Ig-like_fold.
IPR013106. Ig_V-set.
[Graphical view]
PfamiPF07686. V-set. 1 hit.
[Graphical view]
SMARTiSM00406. IGv. 1 hit.
[Graphical view]
SUPFAMiSSF48726. SSF48726. 1 hit.
PROSITEiPS50835. IG_LIKE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P18529-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNFVLSLIFL ALILKGVQCE VHLVESGGGL VKPGGSLKLS CVVSGFTFNK
60 70 80 90 100
YAMSWVRQTP EKRLEWVATI SSGGLYTYYP DSVKGRFTIS RDNAGNTLYL
110
QMSSLRSEDT AMYYCAR
Length:117
Mass (Da):12,991
Last modified:November 1, 1990 - v1
Checksum:i93A04782B78B8FA0
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1171

Sequence databases

PIRiJT0506. HVMS57.

Cross-referencesi

Sequence databases

PIRiJT0506. HVMS57.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1BFVX-ray2.10H21-117[»]
1I8IX-ray2.40B21-117[»]
1I8KX-ray1.80B21-117[»]
ProteinModelPortaliP18529.
SMRiP18529.
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

MaxQBiP18529.
PRIDEiP18529.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Phylogenomic databases

HOVERGENiHBG018013.

Miscellaneous databases

EvolutionaryTraceiP18529.

Family and domain databases

Gene3Di2.60.40.10. 1 hit.
InterProiIPR007110. Ig-like_dom.
IPR013783. Ig-like_fold.
IPR013106. Ig_V-set.
[Graphical view]
PfamiPF07686. V-set. 1 hit.
[Graphical view]
SMARTiSM00406. IGv. 1 hit.
[Graphical view]
SUPFAMiSSF48726. SSF48726. 1 hit.
PROSITEiPS50835. IG_LIKE. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiHVM58_MOUSE
AccessioniPrimary (citable) accession number: P18529
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1990
Last sequence update: November 1, 1990
Last modified: November 2, 2016
This is version 82 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Miscellaneous

This sequence belongs to the VH7183 subfamily.

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.