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Protein

Genome polyprotein

Gene
N/A
Organism
Zucchini yellow mosaic virus (strain California) (ZYMV)
Status
Reviewed-Annotation score: Annotation score: 5 out of 5-Experimental evidence at protein leveli

Functioni

Capsid protein: involved in aphid transmission, cell-to-cell and systemis movement, encapsidation of the viral RNA and in the regulation of viral RNA amplification.1 Publication
Nuclear inclusion protein B: an RNA-dependent RNA polymerase that plays an essential role in the virus replication.1 Publication
Helper component proteinase: required for aphid transmission and also has proteolytic activity. Only cleaves a Gly-Gly dipeptide at its own C-terminus. Interacts with virions and aphid stylets. Acts as a suppressor of RNA-mediated gene silencing, also known as post-transcriptional gene silencing (PTGS), a mechanism of plant viral defense that limits the accumulation of viral RNAs. May have RNA-binding activity (By similarity).By similarity
Cytoplasmic inclusion protein: has helicase activity. It may be involved in replication (By similarity).By similarity
Both 6K peptides are indispensable for virus replication.By similarity
Nuclear inclusion protein A: has RNA-binding and proteolytic activities.1 Publication

Catalytic activityi

Hydrolyzes glutaminyl bonds, and activity is further restricted by preferences for the amino acids in P6 - P1' that vary with the species of potyvirus, e.g. Glu-Xaa-Xaa-Tyr-Xaa-Gln-|-(Ser or Gly) for the enzyme from tobacco etch virus. The natural substrate is the viral polyprotein, but other proteins and oligopeptides containing the appropriate consensus sequence are also cleaved.
Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1).PROSITE-ProRule annotation
Hydrolyzes a Gly-|-Gly bond at its own C-terminus, commonly in the sequence -Tyr-Xaa-Val-Gly-|-Gly, in the processing of the potyviral polyprotein.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei264 – 2641For P1 proteinase activityBy similarity
Active sitei652 – 6521For helper component proteinase activityPROSITE-ProRule annotation
Active sitei725 – 7251For helper component proteinase activityPROSITE-ProRule annotation
Active sitei2087 – 20871For nuclear inclusion protein A activityPROSITE-ProRule annotation
Active sitei2122 – 21221For nuclear inclusion protein A activityPROSITE-ProRule annotation
Active sitei2192 – 21921For nuclear inclusion protein A activityPROSITE-ProRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi1249 – 12568ATPPROSITE-ProRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Helicase, Hydrolase, Nucleotidyltransferase, Protease, RNA-directed RNA polymerase, Suppressor of RNA silencing, Thiol protease, Transferase

Keywords - Biological processi

Viral RNA replication

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BRENDAi3.4.22.45. 6761.

Names & Taxonomyi

Protein namesi
Recommended name:
Genome polyprotein
Cleaved into the following 10 chains:
Alternative name(s):
N-terminal protein
Helper component proteinase (EC:3.4.22.45)
Short name:
HC-pro
6 kDa protein 1
Short name:
6K1
6 kDa protein 2
Short name:
6K2
Alternative name(s):
VPg
Nuclear inclusion protein A (EC:3.4.22.44)
Short name:
NI-a
Short name:
NIa
Alternative name(s):
49 kDa proteinase
Short name:
49 kDa-Pro
NIa-pro
Nuclear inclusion protein B (EC:2.7.7.48)
Short name:
NI-b
Short name:
NIb
Alternative name(s):
RNA-directed RNA polymerase
Capsid protein
Short name:
CP
Alternative name(s):
Coat protein
OrganismiZucchini yellow mosaic virus (strain California) (ZYMV)
Taxonomic identifieri117128 [NCBI]
Taxonomic lineageiVirusesssRNA virusesssRNA positive-strand viruses, no DNA stagePotyviridaePotyvirus
Virus hostiCitrullus lanatus (Watermelon) (Citrullus vulgaris) [TaxID: 3654]
Cucumis melo (Muskmelon) [TaxID: 3656]
Cucumis sativus (Cucumber) [TaxID: 3659]
Cucurbita pepo (Vegetable marrow) (Summer squash) [TaxID: 3663]
Proteomesi
  • UP000008610 Componenti: Genome

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Capsid protein, Helical capsid protein, Virion

Pathology & Biotechi

Mutagenesis

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Mutagenesisi618 – 6181P → A: Complete loss of aphid transmission and binding to virions. 1 Publication
Mutagenesisi619 – 6191T → A: Complete loss of aphid transmission and binding to virions. 1 Publication
Mutagenesisi619 – 6191T → S or V: Strongly reduced aphid transmission and binding to virions. 1 Publication
Mutagenesisi620 – 6201K → E: Slightly reduced aphid transmission and binding to virions. 1 Publication

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 30803080Genome polyproteinPRO_0000420035Add
BLAST
Chaini1 – 310310P1 proteinaseSequence analysisPRO_0000040500Add
BLAST
Chaini311 – 766456Helper component proteinaseSequence analysisPRO_0000040501Add
BLAST
Chaini767 – 1112346Protein P3By similarityPRO_0000040502Add
BLAST
Chaini1113 – 1164526 kDa protein 1By similarityPRO_0000040503Add
BLAST
Chaini1165 – 1798634Cytoplasmic inclusion proteinBy similarityPRO_0000040504Add
BLAST
Chaini1799 – 1851536 kDa protein 2By similarityPRO_0000040505Add
BLAST
Chaini1852 – 2041190Viral genome-linked proteinBy similarityPRO_0000040506Add
BLAST
Chaini2042 – 2284243Nuclear inclusion protein ABy similarityPRO_0000040507Add
BLAST
Chaini2285 – 2801517Nuclear inclusion protein BBy similarityPRO_0000040508Add
BLAST
Chaini2802 – 3080279Capsid proteinBy similarityPRO_0000040509Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei1915 – 19151O-(5'-phospho-RNA)-tyrosineBy similarity

Post-translational modificationi

VPg is uridylylated by the polymerase and is covalently attached to the 5'-end of the genomic RNA. This uridylylated form acts as a nucleotide-peptide primer for the polymerase (By similarity).By similarity
Potyviral RNA is expressed as two polyproteins which undergo post-translational proteolytic processing. Genome polyprotein is processed by NIa-pro, P1 and HC-pro proteinases resulting in the production of at least ten individual proteins. P3N-PIPO polyprotein is cleaved by P1 and HC-pro proteinases resulting in the production of three individual proteins. The P1 proteinase and the HC-pro cleave only their respective C-termini autocatalytically. 6K1 is essential for proper proteolytic separation of P3 from CI (By similarity).By similarity

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sitei310 – 3112Cleavage; by P1 proteinaseSequence analysis
Sitei766 – 7672Cleavage; by autolysisPROSITE-ProRule annotation
Sitei1112 – 11132Cleavage; by NIa-proBy similarity
Sitei1164 – 11652Cleavage; by NIa-proBy similarity
Sitei1798 – 17992Cleavage; by NIa-proBy similarity
Sitei2041 – 20422Cleavage; by NIa-proBy similarity
Sitei2284 – 22852Cleavage; by NIa-proBy similarity
Sitei2801 – 28022Cleavage; by NIa-proBy similarity

Keywords - PTMi

Covalent protein-RNA linkage, Phosphoprotein

Structurei

3D structure databases

ProteinModelPortaliP18479.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini644 – 766123Peptidase C6PROSITE-ProRule annotationAdd
BLAST
Domaini1236 – 1388153Helicase ATP-bindingPROSITE-ProRule annotationAdd
BLAST
Domaini1407 – 1566160Helicase C-terminalPROSITE-ProRule annotationAdd
BLAST
Domaini2042 – 2260219Peptidase C4PROSITE-ProRule annotationAdd
BLAST
Domaini2526 – 2650125RdRp catalyticPROSITE-ProRule annotationAdd
BLAST

Motif

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Motifi362 – 3654Involved in interaction with stylet and aphid transmissionBy similarity
Motifi618 – 6203Involved in virions binding and aphid transmission
Motifi1338 – 13414DECH box
Motifi1891 – 190010Nuclear localization signalSequence analysis

Domaini

The N-terminus of helper component proteinase is involved in interaction with stylets. The central part is involved in interaction with virions and the C-terminus is involved in cell-to cell movement of the virus.

Sequence similaritiesi

Contains 1 helicase ATP-binding domain.PROSITE-ProRule annotation
Contains 1 helicase C-terminal domain.PROSITE-ProRule annotation
Contains 1 peptidase C4 domain.PROSITE-ProRule annotation
Contains 1 peptidase C6 domain.PROSITE-ProRule annotationCurated
Contains 1 RdRp catalytic domain.PROSITE-ProRule annotation

Family and domain databases

Gene3Di3.40.50.300. 2 hits.
InterProiIPR011492. DEAD_Flavivir.
IPR001456. HC-pro.
IPR031159. HC_PRO_CPD_dom.
IPR014001. Helicase_ATP-bd.
IPR001650. Helicase_C.
IPR027417. P-loop_NTPase.
IPR002540. Pept_S30_P1_potyvir.
IPR009003. Peptidase_S1_PA.
IPR001592. Poty_coat.
IPR001730. Potyv_NIa-pro_dom.
IPR013648. PP_Potyviridae.
IPR001205. RNA-dir_pol_C.
IPR007094. RNA-dir_pol_PSvirus.
[Graphical view]
PfamiPF07652. Flavi_DEAD. 1 hit.
PF00271. Helicase_C. 1 hit.
PF00863. Peptidase_C4. 1 hit.
PF00851. Peptidase_C6. 1 hit.
PF01577. Peptidase_S30. 1 hit.
PF00767. Poty_coat. 1 hit.
PF08440. Poty_PP. 1 hit.
PF00680. RdRP_1. 1 hit.
[Graphical view]
PRINTSiPR00966. NIAPOTYPTASE.
SMARTiSM00487. DEXDc. 1 hit.
SM00490. HELICc. 1 hit.
[Graphical view]
SUPFAMiSSF50494. SSF50494. 1 hit.
SSF52540. SSF52540. 2 hits.
PROSITEiPS51744. HC_PRO_CPD. 1 hit.
PS51192. HELICASE_ATP_BIND_1. 1 hit.
PS51194. HELICASE_CTER. 1 hit.
PS51436. POTYVIRUS_NIA_PRO. 1 hit.
PS50507. RDRP_SSRNA_POS. 1 hit.
[Graphical view]

Sequences (2)i

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

This entry describes 2 isoformsi produced by ribosomal frameshifting. AlignAdd to basket

Isoform Genome polyprotein (identifier: P18479-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MASIMIGSIS VPIAKTEQCA NTQVSNRANI VAPGHMATCP LPLKTHMYYR
60 70 80 90 100
HESKKLMQSN KSIDILNNFF STDEMKFRLT RNEMSKLKKG PSGRIVLRKP
110 120 130 140 150
SKQRVFARIE QDEAARKEEA VFLEGNYDDS ITNLARVLPP AVTHNVDVSL
160 170 180 190 200
RSPFYKRTYK KERKKVAQKQ IVQAPLNSLC TRVLKIARNK NIPVEMIGNK
210 220 230 240 250
KTRHTLTFKR FRGCFVGKVS VAHEEGRMRH TEMSYEQFKW LLKAICQVTH
260 270 280 290 300
TERIREEDIK PGCSGWVLGT NHTLTKRYSR LPHLVIRGRD DDGIVNALEQ
310 320 330 340 350
VLFYSEVDHS SSQPEVQFFQ GWRRIFDKFR PSPDHVCKAD HNNEECGELA
360 370 380 390 400
AIFCQALFPV VKLSCQTCRE SLVEVSFEEF KDSLNANFII HKDEWGSFKE
410 420 430 440 450
GSQYDNIFKL IKVATQATQN LKLSSEVMKL VQNHTSTHMK QIQDINKALM
460 470 480 490 500
KGSLVAQDEL DLALKQLLEM TQWFKNHMHL TGEEALKMFR NKRSSKAMIN
510 520 530 540 550
PSLLCGNQLD KNGNFVWGER GYHSKRLFKN FFEEVIPSEG YTKYVVRNFP
560 570 580 590 600
NGTRKLAIGS LIVPLNLDRA RTALLGESIE KKPLTSACVS QQNGNYIHSC
610 620 630 640 650
CCVTMDDGTP MYSELKSPTK RHLVIGASSD PKYIDLPASE AERMYIAKEG
660 670 680 690 700
YCYLSIFLAM LVNVNENEAK DFTKMIRDVL IPMLGQWPSL MDVATAAYIL
710 720 730 740 750
GVFHPETRCA ELPRILVDHA TQTMHVIDSY GSLTVGYHVL KAGTVNHLIQ
760 770 780 790 800
FASNDLQSEM KHYRVGGTPT QRIKLEEQLI KGIFKPKLMM QLLHDDPYIL
810 820 830 840 850
LLGMISPTIL VHMYRMRHFE RGIEIWIKRD HEIGKIFVIL EQLTRKVALA
860 870 880 890 900
EVLVDQLNLI SEASPHLLEI MKGCQDNQRA YVPALDLLTI QVEREFSNKE
910 920 930 940 950
LKTNGYPDLQ QTLFDMREKM YAKQLHNSWQ ELSLLEKSCV TVRLKQFSIF
960 970 980 990 1000
TERNLIQRAK EGKRASSLQF VHECFITTRV HAKSIRDAGV RKLNEALVGT
1010 1020 1030 1040 1050
CKFFFSCGFK IFARCYSDII YLVNVCLVFS LVLQMSNTVR SMIAATREEK
1060 1070 1080 1090 1100
ERAMANKADE NERTLMHMYH IFSKKQDDAP IYNDFLEHVR NVRPDLEETL
1110 1120 1130 1140 1150
LYMAGVEVVS TQAKSAVQIQ FEKIIAVLAL LTMCFDAERS DAIFKILTKL
1160 1170 1180 1190 1200
KTVFGTVGET VRLQGLEDIE SLEDDKRLTI DFDINTNEAH SSTTFDVHFD
1210 1220 1230 1240 1250
DWWNRQLQQN RTVPHYRTTG KFLEFTRNTA AFVANEIASS SEGEFLVRGR
1260 1270 1280 1290 1300
VGSGKSTSLP AHLAKKGKVL LLEPTRPLAE NVSRQLAGDP FFQNVTLRMR
1310 1320 1330 1340 1350
GLSCFGSSNI TVMTSGFAFH YYVNNPHQLM EFDFVIIDEC HVTDSATIAF
1360 1370 1380 1390 1400
NCALKEYNFA GKLIKVSATP PGRECDFDTQ FAVKVKTEDH LSFHAFVGAQ
1410 1420 1430 1440 1450
KTGSNADMVQ HGNNILVYVA SYNEVDMLSK LLTERQFSVT KVDGRTMQLG
1460 1470 1480 1490 1500
KTTIETHGTS QKPHFIVATN IIENGVTLDV ECVVDFGLKV GRRTGQRNRC
1510 1520 1530 1540 1550
VRYNKKSVSY GERIQRLGRV GRSKPGTALR IGHTEKGIET IPEFIATEAA
1560 1570 1580 1590 1600
ALSFAYGLPV TTHGVSTNIL GKCTVKQMKC ALNFELTPFF TTHLIRHDGS
1610 1620 1630 1640 1650
MHPLIHEELK QFKLRDSEMV LNKVALPHQF VSQWMDQSEY ERIGVHVQCH
1660 1670 1680 1690 1700
ESNSIPFYTN GIPDKVYERI WKCIQENKND AVFGKLSSAC STKVSYTLST
1710 1720 1730 1740 1750
DPAALPRTIA IIDHLLAEEM MKRNHFDTIS SAVTGYSFSL AGIADSFRKR
1760 1770 1780 1790 1800
YMRDYTAHNI AILQQARAQL LEFNSKNVNI NNLSDLEGIG VIKSVVLQSK
1810 1820 1830 1840 1850
QEVSSFLGLR GKWDGKKFAN DVILAIMTLL GGGWFMWEYF TKKINEPVRV
1860 1870 1880 1890 1900
ESKKRRSQKL KFRDAYDRKV GREIFGDDDT IGRTFGEAYT KRGKVKGNNN
1910 1920 1930 1940 1950
TKGMGRKTRN FVHLYGVEPE NYSFIRFVDP LTGHTLDEST HTDISLVQEE
1960 1970 1980 1990 2000
FGSIREKFLE NDLISRQSII NKPGIQAYFM GKGTEEALKV DLTPHVPLLL
2010 2020 2030 2040 2050
CRNTNAIAGY PERENELRQT GTPVKVSFKD VPEKNEHVEL ESKSIYKGVR
2060 2070 2080 2090 2100
DYNGISTIVC QLTNDSDGLK ETMYGIGYGP IIITNGHLFR KNNGTLLVRS
2110 2120 2130 2140 2150
WHGEFIVKNT TTLKVHFIEG KDVVLVRMPK DFPPFKSNAS FRAPKREERR
2160 2170 2180 2190 2200
CLVGTNFQEK SLRSTVSESS MTIPEGTGSY WIHWISTNEG DCGLPMVSTT
2210 2220 2230 2240 2250
DGKIIGVHGL ASTVSSKNYF VPFTDDFIAT HLSKLDDLTW TQHWLWQPSK
2260 2270 2280 2290 2300
IAWGTLNLVD EQPGPEFRIS NLVKDLFTSG VETQSKRERW VYESCEGNLR
2310 2320 2330 2340 2350
AVGTAQSALV TKHVVKGKCP FFEEYLQTHA EASAYFRPLM GEYQPSKLNK
2360 2370 2380 2390 2400
EAFKKDFFKY NKPVTVNQLD HDKFLGAVDG VIRMMCDFEF NECRFITDPE
2410 2420 2430 2440 2450
EIYNSLNMKA AIGAQYRGKK KEYFEGLDDF DRERLLFQSC ERLFNGYKGL
2460 2470 2480 2490 2500
WNGSLKAELR PLEKVRANKT RTFTAAPIDT LLGAKVCVDD FNNEFYRKNL
2510 2520 2530 2540 2550
KCPWTVGMTK FYGGWDKLMR SLPDGWLYCH ADGSQFDSSL TPALLNAVLI
2560 2570 2580 2590 2600
IRSFYMEDWW VGQEMLENLY AEIVYTPILA PDGTIFKKFR GNNSGQPSTV
2610 2620 2630 2640 2650
VDNTLMVVIS IYYACMKFGW NCEEIENKLV FFANGDDLIL AVKDEDSGLL
2660 2670 2680 2690 2700
DNMSSSFCEL GLNYDFSERT HKREDLWFMS HQAMLVDGMY TPKLEKERIV
2710 2720 2730 2740 2750
SILEWDRSKE IMHRTEAICA AMIEAWGHTE LLQEIRKFYL WFVEKEEVRE
2760 2770 2780 2790 2800
LAALGKAPYI AETALRKLYT DKGADTSELA RYLQALHQDI FFEQGDTVML
2810 2820 2830 2840 2850
QSGTQPTVAD AGATKKDKED DKGKNKDVTG SGSGEKTVAA VTKDKDVNAG
2860 2870 2880 2890 2900
SHGKIVPRLS KITKKMSLPR VKGNVILDID HLLEYKPDQI ELYNTRASHQ
2910 2920 2930 2940 2950
QFASWFNQVK TEYDLNEQQM GVVMNGFMVW CIENGTSPDI NGVWVMMDGN
2960 2970 2980 2990 3000
EQVEYPLKPI VENAKPTLRQ IMHHFSDAAE AYIEMRNAEA PYMPRYGLLR
3010 3020 3030 3040 3050
NLRDRSLARY AFDFYEVNSK TPERAREAVA QMKAAALSNV SSRLFGLDGN
3060 3070 3080
VATTSEDTER HTARDVNRNM HTLLGVNTMQ
Note: Produced by conventional translation.
Length:3,080
Mass (Da):350,629
Last modified:December 15, 1998 - v2
Checksum:i2A1E501DEA6B9F73
GO
Isoform P3N-PIPO polyprotein (identifier: P0CK13-1) [UniParc]FASTAAdd to basket

The sequence of this isoform can be found in the external entry P0CK13.
Isoforms of the same protein are often annotated in two different entries if their sequences differ significantly.
Note: Produced by -1 ribosomal frameshifting in P3 ORF.
Length:991
Mass (Da):113,426
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti2694 – 26952LE → ST in AAA48511 (PubMed:2185142).Curated
Sequence conflicti2699 – 27013IVS → LFP in AAA48511 (PubMed:2185142).Curated
Sequence conflicti2811 – 28111A → T in AAA48511 (PubMed:2185142).Curated
Sequence conflicti2834 – 28341G → S in AAA48511 (PubMed:2185142).Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L31350 Genomic RNA. Translation: AAA65559.1.
M35095 Genomic RNA. Translation: AAA48511.1.
PIRiJH0103.

Keywords - Coding sequence diversityi

Ribosomal frameshifting

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L31350 Genomic RNA. Translation: AAA65559.1.
M35095 Genomic RNA. Translation: AAA48511.1.
PIRiJH0103.

3D structure databases

ProteinModelPortaliP18479.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Enzyme and pathway databases

BRENDAi3.4.22.45. 6761.

Family and domain databases

Gene3Di3.40.50.300. 2 hits.
InterProiIPR011492. DEAD_Flavivir.
IPR001456. HC-pro.
IPR031159. HC_PRO_CPD_dom.
IPR014001. Helicase_ATP-bd.
IPR001650. Helicase_C.
IPR027417. P-loop_NTPase.
IPR002540. Pept_S30_P1_potyvir.
IPR009003. Peptidase_S1_PA.
IPR001592. Poty_coat.
IPR001730. Potyv_NIa-pro_dom.
IPR013648. PP_Potyviridae.
IPR001205. RNA-dir_pol_C.
IPR007094. RNA-dir_pol_PSvirus.
[Graphical view]
PfamiPF07652. Flavi_DEAD. 1 hit.
PF00271. Helicase_C. 1 hit.
PF00863. Peptidase_C4. 1 hit.
PF00851. Peptidase_C6. 1 hit.
PF01577. Peptidase_S30. 1 hit.
PF00767. Poty_coat. 1 hit.
PF08440. Poty_PP. 1 hit.
PF00680. RdRP_1. 1 hit.
[Graphical view]
PRINTSiPR00966. NIAPOTYPTASE.
SMARTiSM00487. DEXDc. 1 hit.
SM00490. HELICc. 1 hit.
[Graphical view]
SUPFAMiSSF50494. SSF50494. 1 hit.
SSF52540. SSF52540. 2 hits.
PROSITEiPS51744. HC_PRO_CPD. 1 hit.
PS51192. HELICASE_ATP_BIND_1. 1 hit.
PS51194. HELICASE_CTER. 1 hit.
PS51436. POTYVIRUS_NIA_PRO. 1 hit.
PS50507. RDRP_SSRNA_POS. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Characterization of the P1 protein and coding region of the zucchini yellow mosaic virus."
    Wisler G.C., Purcifull D.E., Hiebert E.
    J. Gen. Virol. 76:37-45(1995) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC RNA].
  2. "Nucleotide sequence of the zucchini yellow mosaic virus capsid-encoding gene and its expression in Escherichia coli."
    Gal-On A., Antignus Y., Rosner A., Raccah B.
    Gene 87:273-277(1990) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC RNA] OF 2694-3080.
  3. "Mutations in the HC-Pro gene of zucchini yellow mosaic potyvirus: effects on aphid transmission and binding to purified virions."
    Peng Y.H., Kadoury D., Gal-On A., Huet H., Wang Y., Raccah B.
    J. Gen. Virol. 79:897-904(1998) [PubMed] [Europe PMC] [Abstract]
    Cited for: FUNCTION OF HELPER COMPONENT PROTEINASE, MUTAGENESIS OF PRO-618; THR-619 AND LYS-620.
  4. Cited for: REVIEW.

Entry informationi

Entry nameiPOLG_ZYMVC
AccessioniPrimary (citable) accession number: P18479
Secondary accession number(s): Q89334
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1990
Last sequence update: December 15, 1998
Last modified: October 14, 2015
This is version 130 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Peptidase families
    Classification of peptidase families and list of entries
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.