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Protein

60S ribosomal protein L27a

Gene

Rpl27a

Organism
Rattus norvegicus (Rat)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Ribonucleoprotein, Ribosomal protein

Names & Taxonomyi

Protein namesi
Recommended name:
60S ribosomal protein L27a
Gene namesi
Name:Rpl27a
OrganismiRattus norvegicus (Rat)
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 1

Organism-specific databases

RGDi1309771. Rpl27a.

Subcellular locationi

GO - Cellular componenti

  • cytosolic large ribosomal subunit Source: RGD
Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Initiator methionineiRemoved1 Publication
Chaini2 – 14814760S ribosomal protein L27aPRO_0000104884Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei39 – 391(3S)-3-hydroxyhistidineBy similarity
Modified residuei47 – 471N6-acetyllysineBy similarity
Modified residuei55 – 551N6-acetyllysineBy similarity
Modified residuei68 – 681PhosphoserineBy similarity
Modified residuei110 – 1101N6-acetyllysineBy similarity

Post-translational modificationi

Hydroxylated on His-39 by MINA.By similarity

Keywords - PTMi

Acetylation, Hydroxylation, Phosphoprotein

Proteomic databases

PaxDbiP18445.
PRIDEiP18445.

PTM databases

iPTMnetiP18445.
PhosphoSiteiP18445.

Expressioni

Gene expression databases

GenevisibleiP18445. RN.

Interactioni

Protein-protein interaction databases

BioGridi254258. 1 interaction.
MINTiMINT-4578459.
STRINGi10116.ENSRNOP00000019247.

Structurei

3D structure databases

ProteinModelPortaliP18445.
SMRiP18445. Positions 6-147.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the ribosomal protein L15P family.Curated

Phylogenomic databases

eggNOGiKOG1742. Eukaryota.
COG0200. LUCA.
GeneTreeiENSGT00390000005534.
HOGENOMiHOG000231263.
HOVERGENiHBG054587.
InParanoidiP18445.
KOiK02900.
OMAiARWVSKL.
OrthoDBiEOG78SQKP.
PhylomeDBiP18445.
TreeFamiTF313742.

Family and domain databases

HAMAPiMF_01341. Ribosomal_L15.
InterProiIPR030878. Ribosomal_L15.
IPR001196. Ribosomal_L15_CS.
IPR021131. Ribosomal_L18e/L15P.
[Graphical view]
PfamiPF00828. Ribosomal_L27A. 1 hit.
[Graphical view]
SUPFAMiSSF52080. SSF52080. 1 hit.
PROSITEiPS00475. RIBOSOMAL_L15. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P18445-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPSRLRKTRK LRGHVSHGHG RIGKHRKHPG GRGNAGGMHH HRINFDKYHP
60 70 80 90 100
GYFGKVGMRH YHLKRNQSFC PTVNLDKLWT LVSEQTRVNA AKNKNGVAPI
110 120 130 140
IDVVRSGYYK VLGKGKLPKQ PVIVKAKFFS RRAEEKIKGV GGACVLVA
Length:148
Mass (Da):16,618
Last modified:January 23, 2007 - v3
Checksum:i9CFB1FA50E3504DD
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X52733 mRNA. Translation: CAA36947.1.
PIRiS13071. R5RTLA.
RefSeqiNP_001099760.1. NM_001106290.1.
UniGeneiRn.224527.
Rn.2722.

Genome annotation databases

EnsembliENSRNOT00000019247; ENSRNOP00000019247; ENSRNOG00000014214.
GeneIDi293418.
KEGGirno:293418.
UCSCiRGD:1309771. rat.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X52733 mRNA. Translation: CAA36947.1.
PIRiS13071. R5RTLA.
RefSeqiNP_001099760.1. NM_001106290.1.
UniGeneiRn.224527.
Rn.2722.

3D structure databases

ProteinModelPortaliP18445.
SMRiP18445. Positions 6-147.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi254258. 1 interaction.
MINTiMINT-4578459.
STRINGi10116.ENSRNOP00000019247.

PTM databases

iPTMnetiP18445.
PhosphoSiteiP18445.

Proteomic databases

PaxDbiP18445.
PRIDEiP18445.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSRNOT00000019247; ENSRNOP00000019247; ENSRNOG00000014214.
GeneIDi293418.
KEGGirno:293418.
UCSCiRGD:1309771. rat.

Organism-specific databases

CTDi6157.
RGDi1309771. Rpl27a.

Phylogenomic databases

eggNOGiKOG1742. Eukaryota.
COG0200. LUCA.
GeneTreeiENSGT00390000005534.
HOGENOMiHOG000231263.
HOVERGENiHBG054587.
InParanoidiP18445.
KOiK02900.
OMAiARWVSKL.
OrthoDBiEOG78SQKP.
PhylomeDBiP18445.
TreeFamiTF313742.

Miscellaneous databases

PROiP18445.

Gene expression databases

GenevisibleiP18445. RN.

Family and domain databases

HAMAPiMF_01341. Ribosomal_L15.
InterProiIPR030878. Ribosomal_L15.
IPR001196. Ribosomal_L15_CS.
IPR021131. Ribosomal_L18e/L15P.
[Graphical view]
PfamiPF00828. Ribosomal_L27A. 1 hit.
[Graphical view]
SUPFAMiSSF52080. SSF52080. 1 hit.
PROSITEiPS00475. RIBOSOMAL_L15. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "The primary structure of rat ribosomal proteins: the amino acid sequences of L27a and L28 and corrections in the sequences of S4 and S12."
    Wool I.G., Chan Y.-L., Paz V., Olvera J.
    Biochim. Biophys. Acta 1050:69-73(1990) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA], PROTEIN SEQUENCE OF 2-16.
    Strain: Sprague-Dawley.
    Tissue: Liver.

Entry informationi

Entry nameiRL27A_RAT
AccessioniPrimary (citable) accession number: P18445
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1990
Last sequence update: January 23, 2007
Last modified: July 6, 2016
This is version 107 of the entry and version 3 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. Ribosomal proteins
    Ribosomal proteins families and list of entries
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.