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Protein

Endo-1,4-beta-xylanase A

Gene

xynA

Organism
Bacillus subtilis (strain 168)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Catalytic activityi

Endohydrolysis of (1->4)-beta-D-xylosidic linkages in xylans.

Pathwayi: xylan degradation

This protein is involved in the pathway xylan degradation, which is part of Glycan degradation.
View all proteins of this organism that are known to be involved in the pathway xylan degradation and in Glycan degradation.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei106NucleophilePROSITE-ProRule annotation1 Publication1
Active sitei200Proton donorPROSITE-ProRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionGlycosidase, Hydrolase
Biological processCarbohydrate metabolism, Polysaccharide degradation, Xylan degradation

Enzyme and pathway databases

BioCyciBSUB:BSU18840-MONOMER
BRENDAi3.2.1.8 658
SABIO-RKP18429
UniPathwayiUPA00114

Protein family/group databases

CAZyiGH11 Glycoside Hydrolase Family 11
mycoCLAPiXYN11C_BACSU

Names & Taxonomyi

Protein namesi
Recommended name:
Endo-1,4-beta-xylanase A (EC:3.2.1.8)
Short name:
Xylanase A
Alternative name(s):
1,4-beta-D-xylan xylanohydrolase A
Gene namesi
Name:xynA
Ordered Locus Names:BSU18840
OrganismiBacillus subtilis (strain 168)
Taxonomic identifieri224308 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillus
Proteomesi
  • UP000001570 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Pathology & Biotechi

Mutagenesis

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Mutagenesisi106E → S: Drastically reduced activity. 1 Publication1
Mutagenesisi200E → S: Drastically reduced activity. 1 Publication1

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 28Add BLAST28
ChainiPRO_000000799929 – 213Endo-1,4-beta-xylanase AAdd BLAST185

Proteomic databases

PaxDbiP18429
PRIDEiP18429

Interactioni

Protein-protein interaction databases

IntActiP18429, 2 interactors
MINTiP18429
STRINGi224308.Bsubs1_010100010386

Structurei

Secondary structure

1213
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Beta strandi33 – 38Combined sources6
Beta strandi42 – 48Combined sources7
Beta strandi53 – 60Combined sources8
Beta strandi62 – 72Combined sources11
Beta strandi78 – 88Combined sources11
Beta strandi90 – 101Combined sources12
Turni102 – 104Combined sources3
Beta strandi105 – 116Combined sources12
Beta strandi121 – 128Combined sources8
Beta strandi131 – 145Combined sources15
Beta strandi148 – 162Combined sources15
Beta strandi170 – 173Combined sources4
Helixi174 – 183Combined sources10
Beta strandi190 – 203Combined sources14
Beta strandi206 – 213Combined sources8

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1AXKX-ray2.10A/B29-213[»]
1XXNX-ray1.70A29-213[»]
2B42X-ray2.50B29-213[»]
2B45X-ray2.00X29-213[»]
2B46X-ray2.21X29-213[»]
2DCYX-ray1.40A/B/C/D/E29-213[»]
2DCZX-ray1.90A/B29-213[»]
2QZ3X-ray1.80A/B29-213[»]
2Z79X-ray1.30A/B29-213[»]
3EXUX-ray1.81A/B29-213[»]
3HD8X-ray2.39B/D29-213[»]
5K9YX-ray2.20A/B29-213[»]
5TVVX-ray1.79A/B/C30-213[»]
5TVYX-ray1.00A/B30-213[»]
5TZOX-ray1.67A/B/C30-213[»]
ProteinModelPortaliP18429
SMRiP18429
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP18429

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini29 – 213GH11PROSITE-ProRule annotationAdd BLAST185

Sequence similaritiesi

Keywords - Domaini

Signal

Phylogenomic databases

eggNOGiENOG4107T94 Bacteria
ENOG410YH6C LUCA
HOGENOMiHOG000179135
InParanoidiP18429
KOiK01181
OMAiIEYYVVD
PhylomeDBiP18429

Family and domain databases

Gene3Di2.60.120.180, 1 hit
InterProiView protein in InterPro
IPR013320 ConA-like_dom_sf
IPR013319 GH11/12
IPR018208 GH11_AS_1
IPR033119 GH11_AS_2
IPR033123 GH11_dom
IPR001137 Glyco_hydro_11
PfamiView protein in Pfam
PF00457 Glyco_hydro_11, 1 hit
PRINTSiPR00911 GLHYDRLASE11
SUPFAMiSSF49899 SSF49899, 1 hit
PROSITEiView protein in PROSITE
PS00776 GH11_1, 1 hit
PS00777 GH11_2, 1 hit
PS51761 GH11_3, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P18429-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MFKFKKNFLV GLSAALMSIS LFSATASAAS TDYWQNWTDG GGIVNAVNGS
60 70 80 90 100
GGNYSVNWSN TGNFVVGKGW TTGSPFRTIN YNAGVWAPNG NGYLTLYGWT
110 120 130 140 150
RSPLIEYYVV DSWGTYRPTG TYKGTVKSDG GTYDIYTTTR YNAPSIDGDR
160 170 180 190 200
TTFTQYWSVR QSKRPTGSNA TITFSNHVNA WKSHGMNLGS NWAYQVMATE
210
GYQSSGSSNV TVW
Length:213
Mass (Da):23,345
Last modified:November 1, 1990 - v1
Checksum:i20CBA35238CC0564
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M36648 Genomic DNA Translation: AAA22897.1
AF027868 Genomic DNA Translation: AAB84458.1
AL009126 Genomic DNA Translation: CAB13776.1
PIRiI40569
RefSeqiNP_389765.1, NC_000964.3
WP_003231377.1, NZ_JNCM01000036.1

Genome annotation databases

EnsemblBacteriaiCAB13776; CAB13776; BSU18840
GeneIDi939861
KEGGibsu:BSU18840
PATRICifig|224308.179.peg.2054

Similar proteinsi

Entry informationi

Entry nameiXYNA_BACSU
AccessioniPrimary (citable) accession number: P18429
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1990
Last sequence update: November 1, 1990
Last modified: May 23, 2018
This is version 145 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

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