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Protein

Protein FUN14

Gene

FUN14

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Miscellaneous

Present with 1920 molecules/cell in log phase SD medium.1 Publication

GO - Biological processi

  • autophagy of mitochondrion Source: GO_Central
  • mitochondrion organization Source: SGD
  • phospholipid homeostasis Source: SGD

Enzyme and pathway databases

BioCyciYEAST:G3O-28821-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Protein FUN14
Gene namesi
Name:FUN14
Ordered Locus Names:YAL008W
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
Proteomesi
  • UP000002311 Componenti: Chromosome I

Organism-specific databases

EuPathDBiFungiDB:YAL008W.
SGDiS000000006. FUN14.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei39 – 59HelicalSequence analysisAdd BLAST21
Transmembranei112 – 132HelicalSequence analysisAdd BLAST21
Transmembranei172 – 192HelicalSequence analysisAdd BLAST21

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002024121 – 198Protein FUN14Add BLAST198

Proteomic databases

MaxQBiP18411.
PRIDEiP18411.

Interactioni

Protein-protein interaction databases

BioGridi31758. 30 interactors.
IntActiP18411. 3 interactors.
MINTiMINT-2735020.
STRINGi4932.YAL008W.

Structurei

3D structure databases

ProteinModelPortaliP18411.
SMRiP18411.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the FUN14 family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

InParanoidiP18411.
OMAiGWIRINL.
OrthoDBiEOG092C51LV.

Family and domain databases

InterProiView protein in InterPro
IPR007014. FUN14.
PfamiView protein in Pfam
PF04930. FUN14. 1 hit.

Sequencei

Sequence statusi: Complete.

P18411-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTLAFNMQRL VFRNLNVGKR MFKNVPLWRF NVANKLGKPL TRSVGLGGAG
60 70 80 90 100
IVAGGFYLMN RQPSKLIFND SLGAAVKQQG PLEPTVGNST AITEERRNKI
110 120 130 140 150
SSHKQMFLGS LFGVVLGVTV AKISILFMYV GITSMLLCEW LRYKGWIRIN
160 170 180 190
LKNIKSVIVL KDVDLKKLLI DGLLGTEYMG FKVFFTLSFV LASLNANK
Length:198
Mass (Da):22,063
Last modified:February 1, 1995 - v3
Checksum:iF2AB77E54D53C791
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L05146 Genomic DNA. No translation available.
L22015 Genomic DNA. Translation: AAC04950.1.
AY557707 Genomic DNA. Translation: AAS56033.1.
M36073 Genomic DNA. Translation: AAA35074.2.
BK006935 Genomic DNA. Translation: DAA06980.1.
PIRiS43447.
RefSeqiNP_009394.1. NM_001178153.1.

Genome annotation databases

EnsemblFungiiYAL008W; YAL008W; YAL008W.
GeneIDi851225.
KEGGisce:YAL008W.

Similar proteinsi

Entry informationi

Entry nameiFUN14_YEAST
AccessioniPrimary (citable) accession number: P18411
Secondary accession number(s): D6VPL0
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1990
Last sequence update: February 1, 1995
Last modified: October 25, 2017
This is version 123 of the entry and version 3 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  3. Yeast chromosome I
    Yeast (Saccharomyces cerevisiae) chromosome I: entries and gene names