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P18411 (FUN14_YEAST) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 99. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Interactions·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Protein FUN14
Gene names
Name:FUN14
Ordered Locus Names:YAL008W
OrganismSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) [Reference proteome]
Taxonomic identifier559292 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces

Protein attributes

Sequence length198 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Subcellular location

Membrane; Multi-pass membrane protein Potential.

Miscellaneous

Present with 1920 molecules/cell in log phase SD medium.

Sequence similarities

Belongs to the FUN14 family.

Ontologies

Keywords
   Cellular componentMembrane
   DomainTransmembrane
Transmembrane helix
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Cellular_componentintegral component of membrane

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Binary interactions

With

Entry

#Exp.

IntAct

Notes

ALO1P547831EBI-20609,EBI-2519
UIP4Q089261EBI-20609,EBI-2044051

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 198198Protein FUN14
PRO_0000202412

Regions

Transmembrane39 – 5921Helical; Potential
Transmembrane112 – 13221Helical; Potential
Transmembrane172 – 19221Helical; Potential

Sequences

Sequence LengthMass (Da)Tools
P18411 [UniParc].

Last modified February 1, 1995. Version 3.
Checksum: F2AB77E54D53C791

FASTA19822,063
        10         20         30         40         50         60 
MTLAFNMQRL VFRNLNVGKR MFKNVPLWRF NVANKLGKPL TRSVGLGGAG IVAGGFYLMN 

        70         80         90        100        110        120 
RQPSKLIFND SLGAAVKQQG PLEPTVGNST AITEERRNKI SSHKQMFLGS LFGVVLGVTV 

       130        140        150        160        170        180 
AKISILFMYV GITSMLLCEW LRYKGWIRIN LKNIKSVIVL KDVDLKKLLI DGLLGTEYMG 

       190 
FKVFFTLSFV LASLNANK 

« Hide

References

« Hide 'large scale' references
[1]"Sequencing of chromosome I of Saccharomyces cerevisiae: analysis of the 42 kbp SPO7-CENI-CDC15 region."
Clark M.W., Keng T., Storms R.K., Zhong W.-W., Fortin N., Zeng B., Delaney S., Ouellette B.F.F., Barton A.B., Kaback D.B., Bussey H.
Yeast 10:535-541(1994) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: ATCC 204511 / S288c / AB972.
[2]"The nucleotide sequence of chromosome I from Saccharomyces cerevisiae."
Bussey H., Kaback D.B., Zhong W.-W., Vo D.H., Clark M.W., Fortin N., Hall J., Ouellette B.F.F., Keng T., Barton A.B., Su Y., Davies C.J., Storms R.K.
Proc. Natl. Acad. Sci. U.S.A. 92:3809-3813(1995) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 204508 / S288c.
[3]Saccharomyces Genome Database
Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases
Cited for: GENOME REANNOTATION.
Strain: ATCC 204508 / S288c.
[4]"Approaching a complete repository of sequence-verified protein-encoding clones for Saccharomyces cerevisiae."
Hu Y., Rolfs A., Bhullar B., Murthy T.V.S., Zhu C., Berger M.F., Camargo A.A., Kelley F., McCarron S., Jepson D., Richardson A., Raphael J., Moreira D., Taycher E., Zuo D., Mohr S., Kane M.F., Williamson J. expand/collapse author list , Simpson A.J.G., Bulyk M.L., Harlow E., Marsischky G., Kolodner R.D., LaBaer J.
Genome Res. 17:536-543(2007) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: ATCC 204508 / S288c.
[5]"Molecular cloning of chromosome I DNA from Saccharomyces cerevisiae: isolation, characterization and regulation of the SPO7 sporulation gene."
Whyte W., Koepp L.H., Lamb J., Crowley J.C., Kaback D.B.
Gene 95:65-72(1990) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-74.
[6]"Global analysis of protein expression in yeast."
Ghaemmaghami S., Huh W.-K., Bower K., Howson R.W., Belle A., Dephoure N., O'Shea E.K., Weissman J.S.
Nature 425:737-741(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
L05146 Genomic DNA. No translation available.
L22015 Genomic DNA. Translation: AAC04950.1.
AY557707 Genomic DNA. Translation: AAS56033.1.
M36073 Genomic DNA. Translation: AAA35074.2.
BK006935 Genomic DNA. Translation: DAA06980.1.
PIRS43447.
RefSeqNP_009394.1. NM_001178153.1.

3D structure databases

ProteinModelPortalP18411.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

BioGrid31758. 15 interactions.
IntActP18411. 3 interactions.
MINTMINT-2735020.
STRING4932.YAL008W.

Proteomic databases

PaxDbP18411.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblFungiYAL008W; YAL008W; YAL008W.
GeneID851225.
KEGGsce:YAL008W.

Organism-specific databases

CYGDYAL008w.
SGDS000000006. FUN14.

Phylogenomic databases

eggNOGNOG80282.
OMAGWIRINL.
OrthoDBEOG7KDFP8.

Enzyme and pathway databases

BioCycYEAST:G3O-28821-MONOMER.

Gene expression databases

GenevestigatorP18411.

Family and domain databases

InterProIPR007014. FUN14.
[Graphical view]
PfamPF04930. FUN14. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

NextBio968130.

Entry information

Entry nameFUN14_YEAST
AccessionPrimary (citable) accession number: P18411
Secondary accession number(s): D6VPL0
Entry history
Integrated into UniProtKB/Swiss-Prot: November 1, 1990
Last sequence update: February 1, 1995
Last modified: February 19, 2014
This is version 99 of the entry and version 3 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

Yeast chromosome I

Yeast (Saccharomyces cerevisiae) chromosome I: entries and gene names

Yeast

Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD

SIMILARITY comments

Index of protein domains and families