Reviewed, UniProtKB/Swiss-Prot P18299 (LUXA_KRYAS)

Names and origin

Protein names

Recommended name:
    Alkanal monooxygenase alpha chain
    EC=1.14.14.3
Alternative name(s):
    Bacterial luciferase alpha chain

Gene names

Name:

luxA

Organism

Kryptophanaron alfredi symbiont

Taxonomic identifier

28177 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Vibrionales › Vibrionaceae › light emitting symbionts of fish

Protein attributes

Sequence length	357 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Light-emitting reaction in luminous bacteria.
Catalytic activity	RCHO + reduced FMN + O2 = RCOOH + FMN + H2O + light.
Subunit structure	Heterodimer of an alpha and a beta chain.
Sequence similarities	Belongs to the bacterial luciferase oxidoreductase family.

Ontologies

Keywords
Biological process	Luminescence
Ligand	FMN Flavoprotein
Molecular function	Monooxygenase Oxidoreductase Photoprotein
Gene Ontology (GO)
Biological process	bioluminescence Inferred from electronic annotation. Source: UniProtKB-KW oxidation reduction Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	alkanal monooxygenase (FMN-linked) activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 357	357	Alkanal monooxygenase alpha chain		PRO_0000220163

Sequences

	Sequence		Length	Mass (Da)
	P18299-1 [UniParc]. Last modified November 1, 1990. Version 1. Checksum: 36842D3F6E3DECDF	FASTA	357	40,386
	10 20 30 40 50 60 MKFGNFLLTY QPPQLDQKEV IKRLVNLGQA SESCGFDTAW LLEHHFTEFG LLGNPYVAAA 70 80 90 100 110 120 NLLGATKKLH VGTAAVVLPT AHPVRQLEDV NLLDQMSKGR FKFGICRGLY DKDFRVFGTD 130 140 150 160 170 180 MSNSRELMNS WYDIMTKGMI EGHVSSDNEH IKFPKVKVSP NSYTQRGAPV YVVAESASTT 190 200 210 220 230 240 EWAAERGLPI ILSWIINNNE KKSQLDLYNE IALEHGHDVS NIDHCMSYIT SVDHNSNKAK 250 260 270 280 290 300 DICRDFLAHW YDSYLNATSI FDDSNQTKGY DFNKGQWRNF VLKGHKDTNR RIDYSYEINP 310 320 330 340 350 VGTPQECIEI IQSDIDATGI HNICCGFEAN GSETEIIASM KLFQSDVMPY LKEKSNC

References

[1]

"Relationship of the luminous bacterial symbiont of the Caribbean flashlight fish, Kryptophanaron alfredi (family Anomalopidae) to other luminous bacteria based on bacterial luciferase (luxA) genes." Haygood M.G. Arch. Microbiol. 154:496-503(1990) [PubMed: 2256783] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	M36597 Genomic DNA. Translation: AAA91213.1.
3D structure databases
HSSP	HSSP built from PDB template 1BRL based on UniProtKB P07740.
ModBase	Search...
Enzyme and pathway databases
BRENDA	1.14.14.3. 307252.
Family and domain databases
InterPro	IPR018235. Bacterial_luciferase_CS. IPR011251. Luciferase-like. IPR016048. Luciferase-like_sub. IPR002103. Luciferase_bac. [Graphical view]
Gene3D	G3DSA:3.20.20.30. Luciferase_like. 1 hit.
Pfam	PF00296. Bac_luciferase. 1 hit. [Graphical view]
PRINTS	PR00089. LUCIFERASE.
PROSITE	PS00494. BACTERIAL_LUCIFERASE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

LUXA_KRYAS

Accession

Primary (citable) accession number: P18299

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 1, 1990
Last sequence update:	November 1, 1990
Last modified:	June 16, 2009
This is version 51 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)