ID   MCP_IRV1                Reviewed;         464 AA.
AC   P18162;
DT   01-NOV-1990, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1990, sequence version 1.
DT   08-NOV-2023, entry version 76.
DE   RecName: Full=Major capsid protein;
DE            Short=MCP;
DE   AltName: Full=P50;
GN   Name=MCP;
OS   Tipula iridescent virus (TIV) (Insect iridescent virus type 1).
OC   Viruses; Varidnaviria; Bamfordvirae; Nucleocytoviricota; Megaviricetes;
OC   Pimascovirales; Iridoviridae; Betairidovirinae; Iridovirus;
OC   Invertebrate iridescent virus 1.
OX   NCBI_TaxID=10490;
OH   NCBI_TaxID=41043; Tipula.
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA], AND PARTIAL PROTEIN SEQUENCE.
RX   PubMed=2293661; DOI=10.1128/jvi.64.1.125-136.1990;
RA   Tajbakhsh S., Lee P.E., Watson D.C., Seligy V.L.;
RT   "Molecular cloning, characterization, and expression of the Tipula
RT   iridescent virus capsid gene.";
RL   J. Virol. 64:125-136(1990).
CC   -!- FUNCTION: Major capsid protein that self assembles to form an
CC       icosahedral capsid. Represents around 50% of the total virion protein
CC       mass (By similarity). {ECO:0000250}.
CC   -!- SUBUNIT: Homotrimer. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Virion {ECO:0000305}.
CC   -!- PTM: The N-terminus is blocked.
CC   -!- SIMILARITY: Belongs to the NCLDV major capsid protein family.
CC       {ECO:0000305}.
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DR   EMBL; M33542; AAA46245.1; -; Genomic_DNA.
DR   PIR; A33558; VCXFTI.
DR   SMR; P18162; -.
DR   GO; GO:0019028; C:viral capsid; IEA:UniProtKB-KW.
DR   GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
DR   Gene3D; 2.70.9.10; Adenovirus Type 2 Hexon, domain 4; 1.
DR   Gene3D; 2.70.9.20; Major capsid protein Vp54; 1.
DR   InterPro; IPR031654; Capsid_N.
DR   InterPro; IPR007542; MCP_C.
DR   InterPro; IPR038519; MCP_C_sf.
DR   InterPro; IPR016112; VP_dsDNA_II.
DR   Pfam; PF16903; Capsid_N; 1.
DR   Pfam; PF04451; Capsid_NCLDV; 1.
DR   SUPFAM; SSF49749; Group II dsDNA viruses VP; 2.
PE   1: Evidence at protein level;
KW   Capsid protein; Direct protein sequencing; Late protein; Virion.
FT   CHAIN           1..464
FT                   /note="Major capsid protein"
FT                   /id="PRO_0000222380"
SQ   SEQUENCE   464 AA;  50833 MW;  BCDD65F326270910 CRC64;
     MSMSSSNITS GFIDIATFDE IEKYMYGGPT ATAYFVREIR KSTWFTQVPV PLSRNTGNAA
     FGQEWSVSIS RAGDYLLQTW LRVNIPPVTL SGLLGNTYSL RWTKNLMHNL IREATITFND
     LVAARFDNYH LDFWSAFTVP ASKRNGYDNM IGNVSSLINP VAPGGTLGSV GGINLNLPLP
     FFFSRDTGVA LPTAALPYNE MQINFNFRDW HELLILTNSA LVPPASPYVP IVVGTHISAA
     PVLGPVQVWA NYAIVSNEER RRMGCAIRDI LIEQVQTAPR QNYVPLTNAS PTFDIRFSHA
     IKALFFAVRN KTSAAEWSNY ATSSPVVTGA TVNYEPTGSF DPIANTTLIY ENTNRLGAMG
     SDYFSLINPF YHAPTIPSFI GYHLYSYSLH FYDLDPMGST NYGKLTNVSV VPQASPAAIA
     AAGGTGGQAG SDYPQNYEFV ILAVNNNIVR ISGGETPQNY IAVC
//