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Protein

Major capsid protein

Gene

MCP

Organism
Tipula iridescent virus (TIV) (Insect iridescent virus type 1)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Major capsid protein that self assembles to form an icosahedral capsid. Represents around 50% of the total virion protein mass (By similarity).By similarity

GO - Molecular functioni

  1. structural molecule activity Source: InterPro
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Recommended name:
Major capsid protein
Short name:
MCP
Alternative name(s):
P50
Gene namesi
Name:MCP
OrganismiTipula iridescent virus (TIV) (Insect iridescent virus type 1)
Taxonomic identifieri10490 [NCBI]
Taxonomic lineageiVirusesdsDNA viruses, no RNA stageIridoviridaeIridovirus
Virus hostiTipula [TaxID: 41043]

Subcellular locationi

Virion Curated

GO - Cellular componenti

  1. viral capsid Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Capsid protein, Virion

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 464464Major capsid proteinPRO_0000222380Add
BLAST

Post-translational modificationi

The N-terminus is blocked.

Expressioni

Keywords - Developmental stagei

Late protein

Interactioni

Subunit structurei

Homotrimer.By similarity

Structurei

3D structure databases

ProteinModelPortaliP18162.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the NCLDV major capsid protein family.Curated

Family and domain databases

Gene3Di2.70.9.10. 1 hit.
2.70.9.20. 1 hit.
InterProiIPR016114. ASFV_p72.
IPR016111. Hexon_subdom4.
IPR007542. Virus_major_coat_C.
IPR016112. VP_dsDNA_II.
[Graphical view]
PfamiPF04451. Capsid_NCLDV. 1 hit.
[Graphical view]
SUPFAMiSSF49749. SSF49749. 2 hits.

Sequencei

Sequence statusi: Complete.

P18162-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MSMSSSNITS GFIDIATFDE IEKYMYGGPT ATAYFVREIR KSTWFTQVPV
60 70 80 90 100
PLSRNTGNAA FGQEWSVSIS RAGDYLLQTW LRVNIPPVTL SGLLGNTYSL
110 120 130 140 150
RWTKNLMHNL IREATITFND LVAARFDNYH LDFWSAFTVP ASKRNGYDNM
160 170 180 190 200
IGNVSSLINP VAPGGTLGSV GGINLNLPLP FFFSRDTGVA LPTAALPYNE
210 220 230 240 250
MQINFNFRDW HELLILTNSA LVPPASPYVP IVVGTHISAA PVLGPVQVWA
260 270 280 290 300
NYAIVSNEER RRMGCAIRDI LIEQVQTAPR QNYVPLTNAS PTFDIRFSHA
310 320 330 340 350
IKALFFAVRN KTSAAEWSNY ATSSPVVTGA TVNYEPTGSF DPIANTTLIY
360 370 380 390 400
ENTNRLGAMG SDYFSLINPF YHAPTIPSFI GYHLYSYSLH FYDLDPMGST
410 420 430 440 450
NYGKLTNVSV VPQASPAAIA AAGGTGGQAG SDYPQNYEFV ILAVNNNIVR
460
ISGGETPQNY IAVC
Length:464
Mass (Da):50,833
Last modified:November 1, 1990 - v1
Checksum:iBCDD65F326270910
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M33542 Genomic DNA. Translation: AAA46245.1.
PIRiA33558. VCXFTI.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M33542 Genomic DNA. Translation: AAA46245.1.
PIRiA33558. VCXFTI.

3D structure databases

ProteinModelPortaliP18162.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Family and domain databases

Gene3Di2.70.9.10. 1 hit.
2.70.9.20. 1 hit.
InterProiIPR016114. ASFV_p72.
IPR016111. Hexon_subdom4.
IPR007542. Virus_major_coat_C.
IPR016112. VP_dsDNA_II.
[Graphical view]
PfamiPF04451. Capsid_NCLDV. 1 hit.
[Graphical view]
SUPFAMiSSF49749. SSF49749. 2 hits.
ProtoNetiSearch...

Publicationsi

  1. "Molecular cloning, characterization, and expression of the Tipula iridescent virus capsid gene."
    Tajbakhsh S., Lee P.E., Watson D.C., Seligy V.L.
    J. Virol. 64:125-136(1990) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA], PARTIAL PROTEIN SEQUENCE.

Entry informationi

Entry nameiMCP_IRV1
AccessioniPrimary (citable) accession number: P18162
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1990
Last sequence update: November 1, 1990
Last modified: October 1, 2014
This is version 62 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Direct protein sequencing

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.