Reviewed, UniProtKB/Swiss-Prot P18122 (CATA1_MAIZE)

Names and origin

Protein names

Recommended name:
    Catalase isozyme 1
    EC=1.11.1.6

Gene names

Name:

CAT1

Organism

Zea mays (Maize)

Taxonomic identifier

4577 [NCBI]

Taxonomic lineage

Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › Liliopsida › Poales › Poaceae › PACCAD clade › Panicoideae › Andropogoneae › Zea

Protein attributes

Sequence length	492 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at transcript level.

General annotation (Comments)

Function	Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.
Catalytic activity	2 H2O2 = O2 + 2 H2O.
Cofactor	Heme group.
Subunit structure	Homotetramer.
Subcellular location	Peroxisome.
Tissue specificity	Scutella, milky endosperm of immature kernels, leaves and epicotyls.
Sequence similarities	Belongs to the catalase family.

Ontologies

Keywords
Biological process	Hydrogen peroxide
Cellular component	Peroxisome
Ligand	Heme Iron Metal-binding
Molecular function	Oxidoreductase Peroxidase
Gene Ontology (GO)
Biological process	hydrogen peroxide catabolic process Inferred from electronic annotation. Source: UniProtKB-KW oxidation reduction Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	peroxisome Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	catalase activity Inferred from electronic annotation. Source: EC heme binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 492	492	Catalase isozyme 1		PRO_0000084946
Sites
	Active site	65	1	By similarity
	Active site	138	1	By similarity
	Metal binding	348	1	Iron (heme axial ligand) By similarity
Natural variations
	Natural variant	157	1	A → V in strain: cv. W64A.
	Natural variant	211	1	S → T in strain: cv. W64A.
	Natural variant	329	1	S → I in strain: cv. W64A.
	Natural variant	483	1	P → A in strain: cv. W64A.
Experimental info
	Sequence conflict	332	1	A → G in CAA31056. Ref.1
	Sequence conflict	332	1	A → G in CAA42720. Ref.1
	Sequence conflict	415	1	R → G in CAA31056. Ref.1
	Sequence conflict	415	1	R → G in CAA42720. Ref.1
	Sequence conflict	456	1	H → D in CAA31056. Ref.1
	Sequence conflict	456	1	H → D in CAA42720. Ref.1

Sequences

	Sequence		Length	Mass (Da)
	P18122-1 [UniParc]. Last modified November 1, 1990. Version 1. Checksum: CE10C93BEC1D9529	FASTA	492	56,877
	10 20 30 40 50 60 MDPYKHRPSS GSNSSFWTTN SGAPVWNNNS ALTVGQRGPI LLEDYHLIEK LAQFDRERIP 70 80 90 100 110 120 ERVVHARGAS AKGFFEVTHD VSHLTCADFL RAPGVQTPVI VRFSTVVHER GSPETLRDPR 130 140 150 160 170 180 GFAVKFYTRE GNFDLVGNNM PVFFIRDGMK FPDMVHAFKP NPKTNLQENW RIVDFFSHHP 190 200 210 220 230 240 ESLHMFTFLF DDVGIPLNYR HMEGFGVNTY SLINRDGKPH LVKFHWKPTC GVKCLLDNEA 250 260 270 280 290 300 VTVGGTCHSH ATKDLYDSIA AGNYPEWKLY IQTIDLDHED KFDFDPLDVT KTWPEDIIPL 310 320 330 340 350 360 QPVGRMVLNK NVDNFFAENE QIAFCPAISV PAIHYSDDKL LQTRIFSYAD TQRHRLGPNY 370 380 390 400 410 420 LMLPVNAPKC AHHNNHHDGF MNFMHRDEEV NYFPSRFDPA RHAEKVPIPP RVLTRCREKC 430 440 450 460 470 480 IIQKENNFKQ AGERYRSFDP ARQDRFIQRW VDALTHPRVT HEHRTIWISY WSQCDAALGQ 490 KLPSRLNLKP SM

References

[1]	"Characterization of catalase transcripts and their differential expression in maize." Redinbaugh M.G., Wadsworth G.J., Scandalios J.G. Biochim. Biophys. Acta 951:104-116(1988) [PubMed: 2461221] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA]. Strain: cv. R6-67. Tissue: Scutellum.
[2]	"Characterization of the catalase antioxidant defense gene Cat1 of maize, and its developmentally regulated expression in transgenic tobacco." Guan L., Scandalios J.G. Plant J. 3:527-536(1993) [PubMed: 8220459] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: cv. Wisconsin 64A. Tissue: Leaf.

Cross-references

Sequence databases
EMBLGenBankDDBJ	X12538 mRNA. Translation: CAA31056.1. X60135 Genomic DNA. Translation: CAA42720.1.
PIR	S48124.
RefSeq	NP_001105415.1.
UniGene	Zm.83587
3D structure databases
HSSP	HSSP built from PDB template 1M7S based on UniProtKB P46206.
ModBase	Search...
Protein family/group databases
PeroxiBase	6437. ZmKat1.
Genome annotation databases
GeneID	542369.
Organism-specific databases
Gramene	P18122.
MaizeGDB	13855.
Enzyme and pathway databases
BRENDA	1.11.1.6. 289.
Family and domain databases
InterPro	IPR002226. Catalase. IPR010582. Catalase-rel_immune_responsive. IPR011614. Catalase_N. IPR018028. Catalase_rel_subgroup. [Graphical view]
Gene3D	G3DSA:2.40.180.10. Catalase_N. 1 hit.
PANTHER	PTHR11465. Catalase. 1 hit.
Pfam	PF00199. Catalase. 1 hit. PF06628. Catalase-rel. 1 hit. [Graphical view]
PRINTS	PR00067. CATALASE.
ProDom	PD000510. Catalase. 1 hit. [Graphical view] [Entries sharing at least one domain]
PROSITE	PS00437. CATALASE_1. 1 hit. PS00438. CATALASE_2. 1 hit. PS51402. CATALASE_3. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

CATA1_MAIZE

Accession

Primary (citable) accession number: P18122

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 1, 1990
Last sequence update:	November 1, 1990
Last modified:	June 16, 2009
This is version 72 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

PPAP (Plant Proteome Annotation Project)