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P18122 (CATA1_MAIZE) Reviewed, UniProtKB/Swiss-Prot

Last modified March 19, 2014. Version 96. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Catalase isozyme 1

EC=1.11.1.6
Gene names
Name:CAT1
OrganismZea mays (Maize)
Taxonomic identifier4577 [NCBI]
Taxonomic lineageEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaePACMAD cladePanicoideaeAndropogoneaeZea

Protein attributes

Sequence length492 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Function

Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.

Catalytic activity

2 H2O2 = O2 + 2 H2O.

Cofactor

Heme group.

Subunit structure

Homotetramer.

Subcellular location

Peroxisome.

Tissue specificity

Scutella, milky endosperm of immature kernels, leaves and epicotyls.

Sequence similarities

Belongs to the catalase family.

Ontologies

Keywords
   Biological processHydrogen peroxide
   Cellular componentPeroxisome
   LigandHeme
Iron
Metal-binding
   Molecular functionOxidoreductase
Peroxidase
Gene Ontology (GO)
   Biological_processcell death

Inferred from electronic annotation. Source: EnsemblPlants/Gramene

cell redox homeostasis

Inferred from electronic annotation. Source: EnsemblPlants/Gramene

cellular response to nitrogen starvation

Inferred from electronic annotation. Source: EnsemblPlants/Gramene

cellular response to phosphate starvation

Inferred from electronic annotation. Source: EnsemblPlants/Gramene

cellular response to sulfate starvation

Inferred from electronic annotation. Source: EnsemblPlants/Gramene

hydrogen peroxide catabolic process

Inferred from electronic annotation. Source: UniProtKB-KW

photoperiodism

Inferred from electronic annotation. Source: EnsemblPlants/Gramene

response to cold

Inferred from electronic annotation. Source: EnsemblPlants/Gramene

   Cellular_componentchloroplast

Inferred from electronic annotation. Source: EnsemblPlants/Gramene

cytosolic ribosome

Inferred from electronic annotation. Source: EnsemblPlants/Gramene

mitochondrion

Inferred from electronic annotation. Source: EnsemblPlants/Gramene

peroxisome

Inferred from electronic annotation. Source: UniProtKB-SubCell

stromule

Inferred from electronic annotation. Source: EnsemblPlants/Gramene

   Molecular_functioncatalase activity

Inferred from electronic annotation. Source: UniProtKB-EC

cobalt ion binding

Inferred from electronic annotation. Source: EnsemblPlants/Gramene

heme binding

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 492492Catalase isozyme 1
PRO_0000084946

Sites

Active site651 By similarity
Active site1381 By similarity
Metal binding3481Iron (heme axial ligand) By similarity

Natural variations

Natural variant1571A → V in strain: cv. W64A.
Natural variant2111S → T in strain: cv. W64A.
Natural variant3291S → I in strain: cv. W64A.
Natural variant4831P → A in strain: cv. W64A.

Experimental info

Sequence conflict3321A → G in CAA31056. Ref.1
Sequence conflict3321A → G in CAA42720. Ref.1
Sequence conflict4151R → G in CAA31056. Ref.1
Sequence conflict4151R → G in CAA42720. Ref.1
Sequence conflict4561H → D in CAA31056. Ref.1
Sequence conflict4561H → D in CAA42720. Ref.1

Sequences

Sequence LengthMass (Da)Tools
P18122 [UniParc].

Last modified November 1, 1990. Version 1.
Checksum: CE10C93BEC1D9529

FASTA49256,877
        10         20         30         40         50         60 
MDPYKHRPSS GSNSSFWTTN SGAPVWNNNS ALTVGQRGPI LLEDYHLIEK LAQFDRERIP 

        70         80         90        100        110        120 
ERVVHARGAS AKGFFEVTHD VSHLTCADFL RAPGVQTPVI VRFSTVVHER GSPETLRDPR 

       130        140        150        160        170        180 
GFAVKFYTRE GNFDLVGNNM PVFFIRDGMK FPDMVHAFKP NPKTNLQENW RIVDFFSHHP 

       190        200        210        220        230        240 
ESLHMFTFLF DDVGIPLNYR HMEGFGVNTY SLINRDGKPH LVKFHWKPTC GVKCLLDNEA 

       250        260        270        280        290        300 
VTVGGTCHSH ATKDLYDSIA AGNYPEWKLY IQTIDLDHED KFDFDPLDVT KTWPEDIIPL 

       310        320        330        340        350        360 
QPVGRMVLNK NVDNFFAENE QIAFCPAISV PAIHYSDDKL LQTRIFSYAD TQRHRLGPNY 

       370        380        390        400        410        420 
LMLPVNAPKC AHHNNHHDGF MNFMHRDEEV NYFPSRFDPA RHAEKVPIPP RVLTRCREKC 

       430        440        450        460        470        480 
IIQKENNFKQ AGERYRSFDP ARQDRFIQRW VDALTHPRVT HEHRTIWISY WSQCDAALGQ 

       490 
KLPSRLNLKP SM 

« Hide

References

[1]"Characterization of catalase transcripts and their differential expression in maize."
Redinbaugh M.G., Wadsworth G.J., Scandalios J.G.
Biochim. Biophys. Acta 951:104-116(1988) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [MRNA].
Strain: cv. R6-67.
Tissue: Scutellum.
[2]"Characterization of the catalase antioxidant defense gene Cat1 of maize, and its developmentally regulated expression in transgenic tobacco."
Guan L., Scandalios J.G.
Plant J. 3:527-536(1993) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: cv. Wisconsin 64A.
Tissue: Leaf.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
X12538 mRNA. Translation: CAA31056.1.
X60135 Genomic DNA. Translation: CAA42720.1.
PIRS48124.
RefSeqNP_001105415.1. NM_001111945.1.
UniGeneZm.160908.

3D structure databases

ProteinModelPortalP18122.
ModBaseSearch...
MobiDBSearch...

Protein family/group databases

PeroxiBase6437. ZmKat1.

Proteomic databases

PRIDEP18122.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID542369.
KEGGzma:542369.

Organism-specific databases

GrameneP18122.
MaizeGDB13855.

Phylogenomic databases

HOGENOMHOG000087852.

Family and domain databases

Gene3D2.40.180.10. 1 hit.
InterProIPR018028. Catalase.
IPR020835. Catalase-like_dom.
IPR024708. Catalase_AS.
IPR024711. Catalase_clade1/3.
IPR011614. Catalase_core.
IPR002226. Catalase_haem_BS.
IPR010582. Catalase_immune_responsive.
[Graphical view]
PANTHERPTHR11465. PTHR11465. 1 hit.
PfamPF00199. Catalase. 1 hit.
PF06628. Catalase-rel. 1 hit.
[Graphical view]
PIRSFPIRSF038928. Catalase_clade1-3. 1 hit.
PRINTSPR00067. CATALASE.
SMARTSM01060. Catalase. 1 hit.
[Graphical view]
SUPFAMSSF56634. SSF56634. 1 hit.
PROSITEPS00437. CATALASE_1. 1 hit.
PS00438. CATALASE_2. 1 hit.
PS51402. CATALASE_3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameCATA1_MAIZE
AccessionPrimary (citable) accession number: P18122
Entry history
Integrated into UniProtKB/Swiss-Prot: November 1, 1990
Last sequence update: November 1, 1990
Last modified: March 19, 2014
This is version 96 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families