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Protein

Catalase isozyme 1

Gene

CAT1

Organism
Zea mays (Maize)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.

Catalytic activityi

2 H2O2 = O2 + 2 H2O.PROSITE-ProRule annotation

Cofactori

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei65PROSITE-ProRule annotation1
Active sitei138PROSITE-ProRule annotation1
Metal bindingi348Iron (heme axial ligand)By similarity1

GO - Molecular functioni

  • catalase activity Source: AgBase
  • heme binding Source: InterPro
  • metal ion binding Source: UniProtKB-KW

GO - Biological processi

  • cold acclimation Source: AgBase
  • hydrogen peroxide catabolic process Source: UniProtKB-KW
  • protein heterotetramerization Source: AgBase
  • protein homotetramerization Source: AgBase
  • response to abscisic acid Source: AgBase
  • response to auxin Source: AgBase
  • response to oxidative stress Source: AgBase
  • response to reactive oxygen species Source: AgBase
  • response to xenobiotic stimulus Source: AgBase

Keywordsi

Molecular functionOxidoreductase, Peroxidase
Biological processHydrogen peroxide
LigandHeme, Iron, Metal-binding

Protein family/group databases

PeroxiBasei6437 ZmKat1

Names & Taxonomyi

Protein namesi
Recommended name:
Catalase isozyme 1 (EC:1.11.1.6)
Gene namesi
Name:CAT1
OrganismiZea mays (Maize)
Taxonomic identifieri4577 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaePACMAD cladePanicoideaeAndropogonodaeAndropogoneaeTripsacinaeZea
Proteomesi
  • UP000007305 Componenti: Unplaced

Organism-specific databases

MaizeGDBi13855

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Peroxisome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000849461 – 492Catalase isozyme 1Add BLAST492

Proteomic databases

PaxDbiP18122
PRIDEiP18122

Expressioni

Tissue specificityi

Scutella, milky endosperm of immature kernels, leaves and epicotyls.

Gene expression databases

ExpressionAtlasiP18122 differential

Interactioni

Subunit structurei

Homotetramer.

Protein-protein interaction databases

STRINGi4577.GRMZM2G088212_P01

Structurei

3D structure databases

ProteinModelPortaliP18122
SMRiP18122
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the catalase family.Curated

Phylogenomic databases

eggNOGiKOG0047 Eukaryota
COG0753 LUCA
HOGENOMiHOG000087852
KOiK03781

Family and domain databases

Gene3Di2.40.180.10, 1 hit
InterProiView protein in InterPro
IPR018028 Catalase
IPR024708 Catalase_AS
IPR024711 Catalase_clade1/3
IPR011614 Catalase_core
IPR037060 Catalase_core_sf
IPR002226 Catalase_haem_BS
IPR010582 Catalase_immune_responsive
IPR020835 Catalase_sf
PANTHERiPTHR11465 PTHR11465, 1 hit
PfamiView protein in Pfam
PF00199 Catalase, 1 hit
PF06628 Catalase-rel, 1 hit
PIRSFiPIRSF038928 Catalase_clade1-3, 1 hit
PRINTSiPR00067 CATALASE
SMARTiView protein in SMART
SM01060 Catalase, 1 hit
SUPFAMiSSF56634 SSF56634, 1 hit
PROSITEiView protein in PROSITE
PS00437 CATALASE_1, 1 hit
PS00438 CATALASE_2, 1 hit
PS51402 CATALASE_3, 1 hit

Sequencei

Sequence statusi: Complete.

P18122-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDPYKHRPSS GSNSSFWTTN SGAPVWNNNS ALTVGQRGPI LLEDYHLIEK
60 70 80 90 100
LAQFDRERIP ERVVHARGAS AKGFFEVTHD VSHLTCADFL RAPGVQTPVI
110 120 130 140 150
VRFSTVVHER GSPETLRDPR GFAVKFYTRE GNFDLVGNNM PVFFIRDGMK
160 170 180 190 200
FPDMVHAFKP NPKTNLQENW RIVDFFSHHP ESLHMFTFLF DDVGIPLNYR
210 220 230 240 250
HMEGFGVNTY SLINRDGKPH LVKFHWKPTC GVKCLLDNEA VTVGGTCHSH
260 270 280 290 300
ATKDLYDSIA AGNYPEWKLY IQTIDLDHED KFDFDPLDVT KTWPEDIIPL
310 320 330 340 350
QPVGRMVLNK NVDNFFAENE QIAFCPAISV PAIHYSDDKL LQTRIFSYAD
360 370 380 390 400
TQRHRLGPNY LMLPVNAPKC AHHNNHHDGF MNFMHRDEEV NYFPSRFDPA
410 420 430 440 450
RHAEKVPIPP RVLTRCREKC IIQKENNFKQ AGERYRSFDP ARQDRFIQRW
460 470 480 490
VDALTHPRVT HEHRTIWISY WSQCDAALGQ KLPSRLNLKP SM
Length:492
Mass (Da):56,877
Last modified:November 1, 1990 - v1
Checksum:iCE10C93BEC1D9529
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti332A → G in CAA31056 (PubMed:2461221).Curated1
Sequence conflicti332A → G in CAA42720 (PubMed:2461221).Curated1
Sequence conflicti415R → G in CAA31056 (PubMed:2461221).Curated1
Sequence conflicti415R → G in CAA42720 (PubMed:2461221).Curated1
Sequence conflicti456H → D in CAA31056 (PubMed:2461221).Curated1
Sequence conflicti456H → D in CAA42720 (PubMed:2461221).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Natural varianti157A → V in strain: cv. W64A. 1
Natural varianti211S → T in strain: cv. W64A. 1
Natural varianti329S → I in strain: cv. W64A. 1
Natural varianti483P → A in strain: cv. W64A. 1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X12538 mRNA Translation: CAA31056.1
X60135 Genomic DNA Translation: CAA42720.1
PIRiS48124
RefSeqiNP_001105415.1, NM_001111945.1
UniGeneiZm.160908
Zm.83587

Genome annotation databases

KEGGizma:542369

Similar proteinsi

Entry informationi

Entry nameiCATA1_MAIZE
AccessioniPrimary (citable) accession number: P18122
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1990
Last sequence update: November 1, 1990
Last modified: May 23, 2018
This is version 117 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

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