P18106 (FPS_DROME) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Tyrosine-protein kinase Fps85D
EC=2.7.10.2

Alternative name(s):
dFer

Gene names

Name:	Fps85D
Synonyms:	Fer, fps, HD-179
ORF Names:	CG8874

Organism

Drosophila melanogaster (Fruit fly) [Reference proteome]

Taxonomic identifier

7227 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Protostomia › Ecdysozoa › Panarthropoda › Arthropoda › Mandibulata › Pancrustacea › Hexapoda › Insecta › Dicondylia › Pterygota › Neoptera › Endopterygota › Diptera › Brachycera › Muscomorpha › Eremoneura › Cyclorrhapha › Schizophora › Acalyptratae › Ephydroidea › Drosophilidae › Drosophilinae › Drosophilini › Drosophilina › Drosophiliti › Drosophila › Sophophora › melanogaster group › melanogaster subgroup

Protein attributes

Sequence length	1325 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Catalytic activity	ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate.
Subcellular location	Membrane; Peripheral membrane protein Ref.2.
Tissue specificity	Expressed in many tissues during embryonic development, some expression is transient and absent from most of nervous system. Larvae exhibit graded expression in all imaginal disks and expression in neural tissues. Pupal expression is seen in muscles and varies during development. Expression in adults is strong in the retina and present in ovaries, no expression is present in adult brain. Ref.1
Developmental stage	Isoforms B and D are expressed in identical patterns during all stages of development. Ref.1
Sequence similarities	Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily. Contains 1 FCH domain. Contains 1 protein kinase domain. Contains 1 SH2 domain.
Sequence caution	The sequence AAA93470.1 differs from that shown. Reason: Frameshift at positions 937, 941 and 944.

Ontologies

Keywords
Cellular component	Membrane
Coding sequence diversity	Alternative splicing
Domain	SH2 domain
Ligand	ATP-binding Nucleotide-binding
Molecular function	Developmental protein Kinase Transferase Tyrosine-protein kinase
PTM	Phosphoprotein
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	actin filament bundle assembly Inferred from mutant phenotype PubMed 16831834. Source: FlyBase axon guidance Inferred from mutant phenotype PubMed 16831834. Source: FlyBase dorsal closure, amnioserosa morphology change Inferred from mutant phenotype PubMed 16831834. Source: FlyBase dorsal closure, elongation of leading edge cells Inferred from mutant phenotype PubMed 16831834. Source: FlyBase
Cellular_component	adherens junction Inferred from direct assay PubMed 16831834. Source: FlyBase plasma membrane Inferred from direct assay Ref.2. Source: FlyBase
Molecular_function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW non-membrane spanning protein tyrosine kinase activity Inferred from electronic annotation. Source: EC protein tyrosine kinase activity Inferred from sequence or structural similarity Ref.1. Source: FlyBase
Complete GO annotation...

Alternative products

This entry describes 4 isoforms produced by alternative splicing. [Align] [Select]

Isoform A (identifier: P18106-4)

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

Note: No experimental confirmation available.

Isoform B (identifier: P18106-1)

Also known as: p92;

The sequence of this isoform differs from the canonical sequence as follows:
     426-946: Missing.

Isoform C (identifier: P18106-3)

The sequence of this isoform differs from the canonical sequence as follows:
     1-329: Missing.
     426-946: Missing.

Isoform D (identifier: P18106-2)

Also known as: p45;

The sequence of this isoform differs from the canonical sequence as follows:
     1-932: Missing.

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 1325	1325	Tyrosine-protein kinase Fps85D		PRO_0000088095
Regions
	Domain	1 – 82	82	FCH
	Domain	960 – 1051	92	SH2
	Domain	1063 – 1318	256	Protein kinase
	Nucleotide binding	1069 – 1077	9	ATP By similarity
Sites
	Active site	1185	1	Proton acceptor By similarity
	Binding site	1092	1	ATP By similarity
Amino acid modifications
	Modified residue	1213	1	Phosphotyrosine; by autocatalysis By similarity
Natural variations
	Alternative sequence	1 – 932	932	Missing in isoform D.		VSP_004986
	Alternative sequence	1 – 329	329	Missing in isoform C.		VSP_004987
	Alternative sequence	426 – 946	521	Missing in isoform B and isoform C.		VSP_004988
Experimental info
	Sequence conflict	58	1	I → T in CAA37036. Ref.1
	Sequence conflict	230 – 248	19	ILQEA…KYKEI → TCRRRPSMATSRPTSTRRF in CAA37036. Ref.1
	Sequence conflict	320 – 341	22	GAVRD…NGGSP → EPSGLPGEADEDDRACEWWL A in CAA37036. Ref.1
	Sequence conflict	364	1	S → D in CAA37036. Ref.1
	Sequence conflict	940	1	V → W Ref.2
	Sequence conflict	1050	1	P → T Ref.1
	Sequence conflict	1050	1	P → T Ref.2
	Sequence conflict	1161	1	Q → E Ref.1
	Sequence conflict	1161	1	Q → E Ref.2

Sequences

	Sequence		Length	Mass (Da)
	Isoform A [UniParc]. Last modified March 1, 2004. Version 3. Checksum: 7DFC98D9B9776E78	FASTA	1,325	150,263
	10 20 30 40 50 60 MGFSSALQSR AAHEALIVRQ DAELRLMETM KRSIQMKAKC DKEYAISLTA VAQQGLKIDR 70 80 90 100 110 120 ADEMQGSLIS KSWRSYMDEL DHQAKQFKFN AEQLEVVCDK LTHLSQDKRK ARKAYQEEHA 130 140 150 160 170 180 KIAARLNHLT DEVVRKKSEY QKHLEGYKAL RTRFEENYIK APSRSGRKLD DVRDKYQKAC 190 200 210 220 230 240 RKLHLTHNEY VLSITEAIEV EKDFRNVLLP GLLEHQQSVQ ESFILLWRNI LQEAAQYGDL 250 260 270 280 290 300 TADKYKEIQK RIDTVIGSIN PTEEYGEFTE KYKTSPTTPL LFQFDETLIQ DIPGKLQSST 310 320 330 340 350 360 LTVDNLTVDW LRNRLQELEG AVRDCQEKQM KMIEHVNGGS PVANGSIISN GSNTSNGIQS 370 380 390 400 410 420 NKDSLCRQSK DLNALRCQEK QKQKLVDMIK CALNEVGCEE LPSGCDDDLT LEQNFIENGY 430 440 450 460 470 480 NNEQQRSNST SSPGLGIMNE LMRRGGVLTL LRGRGRHFKR KSTPQPATPM TRSRQGRFNK 490 500 510 520 530 540 LQPRSQSLGS LSVIRDGNGP SPARYEPITN HRLRQAASVH YLGEEIATSS TNPPDLTRLR 550 560 570 580 590 600 RTQCSMLCLG EDEEPVVLAS PAPLTQLTAA VLTNTNNNHI YADLELDKKK DTSPSPECKG 610 620 630 640 650 660 EQIQPKKEQI RIEINQTAPQ NSIDAHLDRI DELNRVLDDR LKRTLQPSDD VNAIESAEEN 670 680 690 700 710 720 HIQTRKLAKD PDSQTKRSSS SSSECRSSKD TSHSKKRSLS FSQKSISNIF SNLKEFSKSP 730 740 750 760 770 780 LVRMGKNHIL NEEQDAKRTQ PSQHHHSSGS DCPTNSSSSS SNNNNNNKNT SSNSNHSASQ 790 800 810 820 830 840 STIITSTITT TITTTTTTTP SKENSRLKFK VPKIQKKSKA IRNTFRSKLL NFQLKRSKPC 850 860 870 880 890 900 KQCTKRRRIH PSKSVFDFAK EFEVEQPAGS AADEQFCNCP PAGQKPVKPS VQISGHKDHP 910 920 930 940 950 960 FESSSGELDE NSDRDIDNDE EEEDSASDDV LSMKDHCYCV PSLAASISLS TNRPLYEEEW 970 980 990 1000 1010 1020 FHGVLPREEV VRLLNNDGDF LVRETIRNEE SQIVLSVCWN GHKHFIVQTT GEGNFRFEGP 1030 1040 1050 1060 1070 1080 PFASIQELIM HQYHSELPVT VKSGAILRRP VCRERWELSN DDVVLLERIG RGNFGDVYKA 1090 1100 1110 1120 1130 1140 KLKSTKLDVA VKTCRMTLPD EQKRKFLQEG RILKQYDHPN IVKLIGICVQ KQPIMIVMEL 1150 1160 1170 1180 1190 1200 VLGGSLLTYL RKNSNGLTTR QQMGMCRDAA AGMRYLESKN CIHRDLAARN CLVDLEHSVK 1210 1220 1230 1240 1250 1260 ISDFGMSREE EEYIVSDGMK QIPVKWTAPE ALNFGKYTSL CDVWSYGILM WEIFSKGDTP 1270 1280 1290 1300 1310 1320 YSGMTNSRAR ERIDTGYRMP TPKSTPEEMY RLMLQCWAAD AESRPHFDEI YNVVDALILR LDNSH
	Isoform B (p92) [UniParc]. Checksum: 6666EA45BF6E5784	FASTA	804	92,439
	10 20 30 40 50 60 MGFSSALQSR AAHEALIVRQ DAELRLMETM KRSIQMKAKC DKEYAISLTA VAQQGLKIDR 70 80 90 100 110 120 ADEMQGSLIS KSWRSYMDEL DHQAKQFKFN AEQLEVVCDK LTHLSQDKRK ARKAYQEEHA 130 140 150 160 170 180 KIAARLNHLT DEVVRKKSEY QKHLEGYKAL RTRFEENYIK APSRSGRKLD DVRDKYQKAC 190 200 210 220 230 240 RKLHLTHNEY VLSITEAIEV EKDFRNVLLP GLLEHQQSVQ ESFILLWRNI LQEAAQYGDL 250 260 270 280 290 300 TADKYKEIQK RIDTVIGSIN PTEEYGEFTE KYKTSPTTPL LFQFDETLIQ DIPGKLQSST 310 320 330 340 350 360 LTVDNLTVDW LRNRLQELEG AVRDCQEKQM KMIEHVNGGS PVANGSIISN GSNTSNGIQS 370 380 390 400 410 420 NKDSLCRQSK DLNALRCQEK QKQKLVDMIK CALNEVGCEE LPSGCDDDLT LEQNFIENGY 430 440 450 460 470 480 NNEQQISLST NRPLYEEEWF HGVLPREEVV RLLNNDGDFL VRETIRNEES QIVLSVCWNG 490 500 510 520 530 540 HKHFIVQTTG EGNFRFEGPP FASIQELIMH QYHSELPVTV KSGAILRRPV CRERWELSND 550 560 570 580 590 600 DVVLLERIGR GNFGDVYKAK LKSTKLDVAV KTCRMTLPDE QKRKFLQEGR ILKQYDHPNI 610 620 630 640 650 660 VKLIGICVQK QPIMIVMELV LGGSLLTYLR KNSNGLTTRQ QMGMCRDAAA GMRYLESKNC 670 680 690 700 710 720 IHRDLAARNC LVDLEHSVKI SDFGMSREEE EYIVSDGMKQ IPVKWTAPEA LNFGKYTSLC 730 740 750 760 770 780 DVWSYGILMW EIFSKGDTPY SGMTNSRARE RIDTGYRMPT PKSTPEEMYR LMLQCWAADA 790 800 ESRPHFDEIY NVVDALILRL DNSH
	Isoform C [UniParc]. Checksum: 09EA965D56F33E62	FASTA	475	54,200
	10 20 30 40 50 60 MKMIEHVNGG SPVANGSIIS NGSNTSNGIQ SNKDSLCRQS KDLNALRCQE KQKQKLVDMI 70 80 90 100 110 120 KCALNEVGCE ELPSGCDDDL TLEQNFIENG YNNEQQISLS TNRPLYEEEW FHGVLPREEV 130 140 150 160 170 180 VRLLNNDGDF LVRETIRNEE SQIVLSVCWN GHKHFIVQTT GEGNFRFEGP PFASIQELIM 190 200 210 220 230 240 HQYHSELPVT VKSGAILRRP VCRERWELSN DDVVLLERIG RGNFGDVYKA KLKSTKLDVA 250 260 270 280 290 300 VKTCRMTLPD EQKRKFLQEG RILKQYDHPN IVKLIGICVQ KQPIMIVMEL VLGGSLLTYL 310 320 330 340 350 360 RKNSNGLTTR QQMGMCRDAA AGMRYLESKN CIHRDLAARN CLVDLEHSVK ISDFGMSREE 370 380 390 400 410 420 EEYIVSDGMK QIPVKWTAPE ALNFGKYTSL CDVWSYGILM WEIFSKGDTP YSGMTNSRAR 430 440 450 460 470 ERIDTGYRMP TPKSTPEEMY RLMLQCWAAD AESRPHFDEI YNVVDALILR LDNSH
	Isoform D (p45) [UniParc]. Checksum: D222275E8240C0FF	FASTA	393	45,192
	10 20 30 40 50 60 MKDHCYCVPS LAASISLSTN RPLYEEEWFH GVLPREEVVR LLNNDGDFLV RETIRNEESQ 70 80 90 100 110 120 IVLSVCWNGH KHFIVQTTGE GNFRFEGPPF ASIQELIMHQ YHSELPVTVK SGAILRRPVC 130 140 150 160 170 180 RERWELSNDD VVLLERIGRG NFGDVYKAKL KSTKLDVAVK TCRMTLPDEQ KRKFLQEGRI 190 200 210 220 230 240 LKQYDHPNIV KLIGICVQKQ PIMIVMELVL GGSLLTYLRK NSNGLTTRQQ MGMCRDAAAG 250 260 270 280 290 300 MRYLESKNCI HRDLAARNCL VDLEHSVKIS DFGMSREEEE YIVSDGMKQI PVKWTAPEAL 310 320 330 340 350 360 NFGKYTSLCD VWSYGILMWE IFSKGDTPYS GMTNSRARER IDTGYRMPTP KSTPEEMYRL 370 380 390 MLQCWAADAE SRPHFDEIYN VVDALILRLD NSH

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"A gene related to the proto-oncogene fps/fes is expressed at diverse times during the life cycle of Drosophila melanogaster." Katzen A.L., Montarras D., Jackson J., Paulson R.F., Kornberg T., Bishop J.M. Mol. Cell. Biol. 11:226-239(1991) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM B), TISSUE SPECIFICITY, DEVELOPMENTAL STAGE. Tissue: Embryo and Head.
[2]	"The DFer gene of Drosophila melanogaster encodes two membrane-associated proteins that can both transform vertebrate cells." Paulson R.F., Jackson J., Immergluck K., Bishop J.M. Oncogene 14:641-652(1997) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS B AND D), SUBCELLULAR LOCATION. Tissue: Embryo and Head.
[3]	"The genome sequence of Drosophila melanogaster." Adams M.D., Celniker S.E., Holt R.A., Evans C.A., Gocayne J.D., Amanatides P.G., Scherer S.E., Li P.W., Hoskins R.A., Galle R.F., George R.A., Lewis S.E., Richards S., Ashburner M., Henderson S.N., Sutton G.G., Wortman J.R., Yandell M.D. , Zhang Q., Chen L.X., Brandon R.C., Rogers Y.-H.C., Blazej R.G., Champe M., Pfeiffer B.D., Wan K.H., Doyle C., Baxter E.G., Helt G., Nelson C.R., Miklos G.L.G., Abril J.F., Agbayani A., An H.-J., Andrews-Pfannkoch C., Baldwin D., Ballew R.M., Basu A., Baxendale J., Bayraktaroglu L., Beasley E.M., Beeson K.Y., Benos P.V., Berman B.P., Bhandari D., Bolshakov S., Borkova D., Botchan M.R., Bouck J., Brokstein P., Brottier P., Burtis K.C., Busam D.A., Butler H., Cadieu E., Center A., Chandra I., Cherry J.M., Cawley S., Dahlke C., Davenport L.B., Davies P., de Pablos B., Delcher A., Deng Z., Mays A.D., Dew I., Dietz S.M., Dodson K., Doup L.E., Downes M., Dugan-Rocha S., Dunkov B.C., Dunn P., Durbin K.J., Evangelista C.C., Ferraz C., Ferriera S., Fleischmann W., Fosler C., Gabrielian A.E., Garg N.S., Gelbart W.M., Glasser K., Glodek A., Gong F., Gorrell J.H., Gu Z., Guan P., Harris M., Harris N.L., Harvey D.A., Heiman T.J., Hernandez J.R., Houck J., Hostin D., Houston K.A., Howland T.J., Wei M.-H., Ibegwam C., Jalali M., Kalush F., Karpen G.H., Ke Z., Kennison J.A., Ketchum K.A., Kimmel B.E., Kodira C.D., Kraft C.L., Kravitz S., Kulp D., Lai Z., Lasko P., Lei Y., Levitsky A.A., Li J.H., Li Z., Liang Y., Lin X., Liu X., Mattei B., McIntosh T.C., McLeod M.P., McPherson D., Merkulov G., Milshina N.V., Mobarry C., Morris J., Moshrefi A., Mount S.M., Moy M., Murphy B., Murphy L., Muzny D.M., Nelson D.L., Nelson D.R., Nelson K.A., Nixon K., Nusskern D.R., Pacleb J.M., Palazzolo M., Pittman G.S., Pan S., Pollard J., Puri V., Reese M.G., Reinert K., Remington K., Saunders R.D.C., Scheeler F., Shen H., Shue B.C., Siden-Kiamos I., Simpson M., Skupski M.P., Smith T.J., Spier E., Spradling A.C., Stapleton M., Strong R., Sun E., Svirskas R., Tector C., Turner R., Venter E., Wang A.H., Wang X., Wang Z.-Y., Wassarman D.A., Weinstock G.M., Weissenbach J., Williams S.M., Woodage T., Worley K.C., Wu D., Yang S., Yao Q.A., Ye J., Yeh R.-F., Zaveri J.S., Zhan M., Zhang G., Zhao Q., Zheng L., Zheng X.H., Zhong F.N., Zhong W., Zhou X., Zhu S.C., Zhu X., Smith H.O., Gibbs R.A., Myers E.W., Rubin G.M., Venter J.C. Science 287:2185-2195(2000) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Berkeley.
[4]	"Annotation of the Drosophila melanogaster euchromatic genome: a systematic review." Misra S., Crosby M.A., Mungall C.J., Matthews B.B., Campbell K.S., Hradecky P., Huang Y., Kaminker J.S., Millburn G.H., Prochnik S.E., Smith C.D., Tupy J.L., Whitfield E.J., Bayraktaroglu L., Berman B.P., Bettencourt B.R., Celniker S.E., de Grey A.D.N.J. , Drysdale R.A., Harris N.L., Richter J., Russo S., Schroeder A.J., Shu S.Q., Stapleton M., Yamada C., Ashburner M., Gelbart W.M., Rubin G.M., Lewis S.E. Genome Biol. 3:RESEARCH0083.1-RESEARCH0083.22(2002) [PubMed] [Europe PMC] [Abstract] Cited for: GENOME REANNOTATION, ALTERNATIVE SPLICING. Strain: Berkeley.
[5]	Stapleton M., Brokstein P., Hong L., Agbayani A., Carlson J.W., Champe M., Chavez C., Dorsett V., Dresnek D., Farfan D., Frise E., George R.A., Gonzalez M., Guarin H., Kronmiller B., Li P.W., Liao G., Miranda A. , Mungall C.J., Nunoo J., Pacleb J.M., Paragas V., Park S., Patel S., Phouanenavong S., Wan K.H., Yu C., Lewis S.E., Rubin G.M., Celniker S.E. Submitted (FEB-2003) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM A). Strain: Berkeley. Tissue: Head.
[6]	"Sampling the genomic pool of protein tyrosine kinase genes using the polymerase chain reaction with genomic DNA." Oates A.C., Wollberg P., Achen M.G., Wilks A.F. Biochem. Biophys. Res. Commun. 249:660-667(1998) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1191-1241.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	X52844 mRNA. Translation: CAA37036.1. U50450 mRNA. Translation: AAA93470.1. Frameshift. AE014297 Genomic DNA. Translation: AAF54366.1. AE014297 Genomic DNA. Translation: AAF54367.3. AE014297 Genomic DNA. Translation: AAN13420.1. AE014297 Genomic DNA. Translation: AAN13421.1. BT003462 mRNA. Translation: AAO39465.1. AJ002916 Genomic DNA. Translation: CAA05751.1.
PIR	OKFFPS. A39670.
RefSeq	NP_524288.3. NM_079564.4. NP_731341.1. NM_169274.2. NP_731342.1. NM_169275.2. NP_731343.1. NM_169276.2.
UniGene	Dm.8026.
3D structure databases
ProteinModelPortal	P18106.
SMR	P18106. Positions 1-306, 953-1320.
ModBase	Search...
Protein-protein interaction databases
IntAct	P18106. 4 interactions.
MINT	MINT-892362.
Proteomic databases
PaxDb	P18106.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblMetazoa	FBtr0082052; FBpp0081530; FBgn0000723.
GeneID	41118.
KEGG	dme:Dmel_CG8874.
Organism-specific databases
CTD	41118.
FlyBase	FBgn0000723. Fps85D.
Phylogenomic databases
eggNOG	COG0515.
GeneTree	ENSGT00600000084126.
InParanoid	P18106.
OMA	HIYADLE.
OrthoDB	EOG4PZGNM.
PhylomeDB	P18106.
Enzyme and pathway databases
BRENDA	2.7.10.2. 1994.
Gene expression databases
Bgee	P18106.
GermOnline	CG8874. Drosophila melanogaster.
Family and domain databases
Gene3D	3.30.505.10. 1 hit.
InterPro	IPR001060. FCH_dom. IPR011009. Kinase-like_dom. IPR000719. Prot_kinase_cat_dom. IPR017441. Protein_kinase_ATP_BS. IPR001245. Ser-Thr/Tyr_kinase_cat_dom. IPR000980. SH2. IPR008266. Tyr_kinase_AS. IPR020635. Tyr_kinase_cat_dom. [Graphical view]
Pfam	PF00611. FCH. 1 hit. PF07714. Pkinase_Tyr. 1 hit. PF00017. SH2. 1 hit. [Graphical view]
PRINTS	PR00109. TYRKINASE.
SMART	SM00055. FCH. 1 hit. SM00252. SH2. 1 hit. SM00219. TyrKc. 1 hit. [Graphical view]
SUPFAM	SSF56112. Kinase_like. 1 hit.
PROSITE	PS50133. FCH. 1 hit. PS00107. PROTEIN_KINASE_ATP. 1 hit. PS50011. PROTEIN_KINASE_DOM. 1 hit. PS00109. PROTEIN_KINASE_TYR. 1 hit. PS50001. SH2. 1 hit. [Graphical view]
ProtoNet	Search...
Other
GenomeRNAi	41118.
NextBio	822270.

Entry information

Entry name

FPS_DROME

Accession

Primary (citable) accession number: P18106
Secondary accession number(s): Q27576 , Q86P62, Q8INP1, Q8INP2, Q9TYI1, Q9VHE7, Q9VHE8

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 1, 1990
Last sequence update:	March 1, 2004
Last modified:	May 1, 2013
This is version 147 of the entry and version 3 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Drosophila annotation project