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P17989 (GUB_FIBSS) Reviewed, UniProtKB/Swiss-Prot

Last modified November 13, 2013. Version 93. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Beta-glucanase

EC=3.2.1.73
Alternative name(s):
1,3-1,4-beta-D-glucan 4-glucanohydrolase
Endo-beta-1,3-1,4 glucanase
Lichenase
Mixed linkage beta-glucanase
Gene names
Ordered Locus Names:Fisuc_2961, FSU_0226
OrganismFibrobacter succinogenes (strain ATCC 19169 / S85) [Complete proteome] [HAMAP]
Taxonomic identifier59374 [NCBI]
Taxonomic lineageBacteriaFibrobacteresFibrobacteralesFibrobacteraceaeFibrobacter

Protein attributes

Sequence length349 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at protein level

General annotation (Comments)

Catalytic activity

Hydrolysis of (1->4)-beta-D-glucosidic linkages in beta-D-glucans containing (1->3)- and (1->4)-bonds.

Sequence similarities

Belongs to the glycosyl hydrolase 16 family.

Ontologies

Keywords
   DomainRepeat
Signal
   Molecular functionGlycosidase
Hydrolase
   Technical term3D-structure
Complete proteome
Direct protein sequencing
Gene Ontology (GO)
   Biological_processcarbohydrate metabolic process

Inferred from electronic annotation. Source: InterPro

   Molecular_functionlicheninase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 2727 Ref.1
Chain28 – 349322Beta-glucanase
PRO_0000011793

Regions

Repeat271 – 27771
Repeat278 – 28472
Repeat285 – 29173
Repeat292 – 29874
Repeat301 – 30775
Region271 – 307375 X 7 AA tandem repeats of P-X-S-S-S-S-X

Sites

Active site791Nucleophile By similarity
Active site831Proton donor By similarity

Secondary structure

..................................................... 349
Helix Strand Turn

Details...

Sequences

Sequence LengthMass (Da)Tools
P17989 [UniParc].

Last modified November 1, 1990. Version 1.
Checksum: 16DC4F5BDEFC578A

FASTA34937,738
        10         20         30         40         50         60 
MNIKKTAVKS ALAVAAAAAA LTTNVSAKDF SGAELYTLEE VQYGKFEARM KMAAASGTVS 

        70         80         90        100        110        120 
SMFLYQNGSE IADGRPWVEV DIEVLGKNPG SFQSNIITGK AGAQKTSEKH HAVSPAADQA 

       130        140        150        160        170        180 
FHTYGLEWTP NYVRWTVDGQ EVRKTEGGQV SNLTGTQGLR FNLWSSESAA WVGQFDESKL 

       190        200        210        220        230        240 
PLFQFINWVK VYKYTPGQGE GGSDFTLDWT DNFDTFDGSR WGKGDWTFDG NRVDLTDKNI 

       250        260        270        280        290        300 
YSRDGMLILA LTRKGQESFN GQVPRDDEPA PQSSSSAPAS SSSVPASSSS VPASSSSAFV 

       310        320        330        340 
PPSSSSATNA IHGMRTTPAV AKEHRNLVNA KGAKVNPNGH KRYRVNFEH 

« Hide

References

« Hide 'large scale' references
[1]"DNA sequence of a Fibrobacter succinogenes mixed-linkage beta-glucanase (1,3-1,4-beta-D-glucan 4-glucanohydrolase) gene."
Teather R.M., Erfle J.D.
J. Bacteriol. 172:3837-3841(1990) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA], PROTEIN SEQUENCE OF 28-57.
[2]"Complete sequence of Fibrobacter succinogenes subsp. succinogenes S85."
US DOE Joint Genome Institute
Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Tice H., Bruce D., Goodwin L., Pitluck S., Chertkov O., Detter J.C., Han C., Tapia R., Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Weimer P.J. expand/collapse author list , Stevenson D.M., Boyum J., Brumm P.I., Mead D.
Submitted (OCT-2009) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 19169 / S85.
[3]"Complete sequence of Fibrobacter succinogenes subsp. succinogenes S85."
Durkin A.S., Nelson K.E., Morrison M., Forsberg C.W., Wilson D.B., Russell J.B., Cann I.K.O., Mackie R.I., White B.A.
Submitted (AUG-2010) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 19169 / S85.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
M33676 Genomic DNA. Translation: AAA24896.1.
CP001792 Genomic DNA. Translation: ACX76541.1.
CP002158 Genomic DNA. Translation: ADL24776.1.
PIRA44507.
RefSeqYP_003251023.1. NC_013410.1.
YP_005820380.1. NC_017448.1.

3D structure databases

PDBe
RCSB PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
1MVEX-ray1.70A25-266[»]
1ZM1X-ray2.30A/B27-267[»]
2R49X-ray2.20A26-266[»]
3AXDX-ray1.53A/B25-271[»]
3AXEX-ray1.53A25-271[»]
3H0OX-ray1.40A27-266[»]
3HR9X-ray1.70A26-266[»]
ProteinModelPortalP17989.
SMRP17989. Positions 25-266.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING59374.Fisuc_2961.

Protein family/group databases

CAZyGH16. Glycoside Hydrolase Family 16.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaACX76541; ACX76541; Fisuc_2961.
ADL24776; ADL24776; FSU_0226.
GeneID12431871.
8523608.
KEGGfsc:FSU_0226.
fsu:Fisuc_2961.
PATRIC32145677. VBIFibSuc28982_2886.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG2273.
OMASWQSNII.
OrthoDBEOG6JB18P.
ProtClustDBCLSK956259.

Family and domain databases

Gene3D2.60.120.200. 1 hit.
InterProIPR008264. Beta_glucanase.
IPR008985. ConA-like_lec_gl_sf.
IPR013320. ConA-like_subgrp.
IPR000757. Glyco_hydro_16.
IPR008263. Glycoside_hydrolase_16_AS.
[Graphical view]
PfamPF00722. Glyco_hydro_16. 1 hit.
[Graphical view]
PRINTSPR00737. GLHYDRLASE16.
SUPFAMSSF49899. SSF49899. 1 hit.
PROSITEPS01034. GLYCOSYL_HYDROL_F16. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

EvolutionaryTraceP17989.

Entry information

Entry nameGUB_FIBSS
AccessionPrimary (citable) accession number: P17989
Secondary accession number(s): C9RPK9, D9S550
Entry history
Integrated into UniProtKB/Swiss-Prot: November 1, 1990
Last sequence update: November 1, 1990
Last modified: November 13, 2013
This is version 93 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PDB cross-references

Index of Protein Data Bank (PDB) cross-references

Glycosyl hydrolases

Classification of glycosyl hydrolase families and list of entries