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Reviewed, UniProtKB/Swiss-Prot P17989 (GUB_FIBSS)

Last modified February 9, 2010. Version 72. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

Names and origin

Protein namesRecommended name:
    Beta-glucanase
    EC=3.2.1.73
Alternative name(s):
    Endo-beta-1,3-1,4 glucanase
    1,3-1,4-beta-D-glucan 4-glucanohydrolase
    Mixed linkage beta-glucanase
    Lichenase
Gene names
Ordered Locus Names: Fisuc_2961
OrganismFibrobacter succinogenes (strain ATCC 19169 / S85) [Complete proteome] [HAMAP]
Taxonomic identifier59374 [NCBI]
Taxonomic lineageBacteriaFibrobacteresFibrobacteralesFibrobacteraceaeFibrobacter

Protein attributes

Sequence length349 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at protein level.

General annotation (Comments)

Catalytic activity

Hydrolysis of (1->4)-beta-D-glucosidic linkages in beta-D-glucans containing (1->3)- and (1->4)-bonds.

Sequence similarities

Belongs to the glycosyl hydrolase 16 family.

Ontologies

Keywords
   DomainRepeat
Signal
   Molecular functionGlycosidase
Hydrolase
   Technical term3D-structure
Complete proteome
Direct protein sequencing
Gene Ontology (GO)
   Biological processcarbohydrate metabolic process

Inferred from electronic annotation. Source: InterPro

   Molecular functionlicheninase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 2727 Ref.1
Chain28 – 349322Beta-glucanase
PRO_0000011793

Regions

Repeat271 – 27771
Repeat278 – 28472
Repeat285 – 29173
Repeat292 – 29874
Repeat301 – 30775
Region271 – 307375 X 7 AA tandem repeats of P-X-S-S-S-S-X

Sites

Active site791Nucleophile By similarity
Active site831Proton donor By similarity

Secondary structure

................................................ 349
Helix Strand Turn

Details...

Sequences

Sequence LengthMass (Da)Tools
P17989-1 [UniParc].

Last modified November 1, 1990. Version 1.
Checksum: 16DC4F5BDEFC578A

FASTA34937,738
        10         20         30         40         50         60 
MNIKKTAVKS ALAVAAAAAA LTTNVSAKDF SGAELYTLEE VQYGKFEARM KMAAASGTVS 

        70         80         90        100        110        120 
SMFLYQNGSE IADGRPWVEV DIEVLGKNPG SFQSNIITGK AGAQKTSEKH HAVSPAADQA 

       130        140        150        160        170        180 
FHTYGLEWTP NYVRWTVDGQ EVRKTEGGQV SNLTGTQGLR FNLWSSESAA WVGQFDESKL 

       190        200        210        220        230        240 
PLFQFINWVK VYKYTPGQGE GGSDFTLDWT DNFDTFDGSR WGKGDWTFDG NRVDLTDKNI 

       250        260        270        280        290        300 
YSRDGMLILA LTRKGQESFN GQVPRDDEPA PQSSSSAPAS SSSVPASSSS VPASSSSAFV 

       310        320        330        340 
PPSSSSATNA IHGMRTTPAV AKEHRNLVNA KGAKVNPNGH KRYRVNFEH 

« Hide

References

« Hide 'large scale' references
[1]"DNA sequence of a Fibrobacter succinogenes mixed-linkage beta-glucanase (1,3-1,4-beta-D-glucan 4-glucanohydrolase) gene."
Teather R.M., Erfle J.D.
J. Bacteriol. 172:3837-3841(1990) [PubMed: 2193918] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA], PROTEIN SEQUENCE OF 28-57.
[2]"Complete sequence of Fibrobacter succinogenes subsp. succinogenes S85."
Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Tice H., Bruce D., Goodwin L., Pitluck S., Chertkov O., Detter J.C., Han C., Tapia R., Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Weimer P.J. expand/collapse author list , Stevenson D.M., Boyum J., Brumm P.I., Mead D.
Submitted (OCT-2009) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
M33676 Genomic DNA. Translation: AAA24896.1.
CP001792 Genomic DNA. Translation: ACX76541.1.
PIRA44507.
RefSeqYP_003251023.1.

3D structure databases

PDBe
RCSB PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
1MVEX-ray1.70A25-266[»]
1ZM1X-ray2.30A/B27-267[»]
2R49X-ray2.20A26-266[»]
3HR9X-ray1.70A26-266[»]
ModBaseSearch...

Protein family/group databases

CAZyGH16. Glycoside Hydrolase Family 16.

Genome annotation databases

GeneID8523608.

Organism-specific databases

CMRSearch...

Enzyme and pathway databases

BRENDA3.2.1.73. 15235.

Family and domain databases

InterProIPR008264. Beta_glucanase.
IPR008985. ConA-like_lec_gl.
IPR013320. ConA-like_subgrp.
IPR000757. Glyco_hydro_16.
IPR008263. Glycoside_hydrolase_16_AS.
[Graphical view]
Gene3DG3DSA:2.60.120.200. ConA_like_subgrp. 1 hit.
PfamPF00722. Glyco_hydro_16. 1 hit.
[Graphical view]
PRINTSPR00737. GLHYDRLASE16.
PROSITEPS01034. GLYCOSYL_HYDROL_F16. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameGUB_FIBSS
AccessionPrimary (citable) accession number: P17989
Secondary accession number(s): C9RPK9
Entry history
Integrated into UniProtKB/Swiss-Prot: November 1, 1990
Last sequence update: November 1, 1990
Last modified: February 9, 2010
This is version 72 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectHAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)

Relevant documents

Glycosyl hydrolases

Classification of glycosyl hydrolase families and list of entries

PDB cross-references

Index of Protein Data Bank (PDB) cross-references

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents