Reviewed, UniProtKB/Swiss-Prot P17977 (CATG_RAT)

Names and origin

Protein names

Recommended name:
    Cathepsin G
    EC=3.4.21.20

Gene names

Name:

Ctsg

Organism

Rattus norvegicus (Rat)

Taxonomic identifier

10116 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Rattus

Protein attributes

Sequence length	26 AA.
Sequence status	Fragment.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at protein level.

General annotation (Comments)

Catalytic activity	Specificity similar to chymotrypsin C.
Sequence similarities	Belongs to the peptidase S1 family. Contains 1 peptidase S1 domain.

Ontologies

Keywords
Molecular function	Hydrolase Protease Serine protease
Technical term	Direct protein sequencing
Gene Ontology (GO)
Biological process	proteolysis Inferred from electronic annotation. Source: InterPro
Molecular function	serine-type endopeptidase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – ›26	›26	Cathepsin G		PRO_0000088661
Regions
	Domain	1 – ›26	›26	Peptidase S1
Experimental info
	Non-terminal residue	26	1

Sequences

	Sequence		Length	Mass (Da)
	P17977-1 [UniParc]. Last modified November 1, 1990. Version 1. Checksum: 11CB1B2E95EC8536	FASTA	26	2,867
	10 20 IIGGREARPN SHPYMAFLLI QSPEGL

References

[1]	"Purification and N-terminal amino-acid sequence analysis of rat polymorphonuclear leukocyte cathepsin G." Bjoerk P., Ohlsson K. Biol. Chem. Hoppe-Seyler 371:595-601(1990) [PubMed: 2222858] [Abstract] Cited for: PROTEIN SEQUENCE. Strain: Sprague-Dawley and Wistar.

Cross-references

Sequence databases
IPI	IPI00561543.
PIR	S10608.
UniGene	Rn.103332
3D structure databases
ModBase	Search...
Protein family/group databases
MEROPS	S01.133.
Genome annotation databases
Ensembl	ENSRNOG00000020647. Rattus norvegicus. [Contig view]
Organism-specific databases
RGD	1307681. Ctsg.
Phylogenomic databases
HOVERGEN	P17977.
Enzyme and pathway databases
BRENDA	3.4.21.20. 248.
Family and domain databases
InterPro	IPR018114. Peptidase_S1/S6_AS. IPR001254. Peptidase_S1_S6. [Graphical view]
Pfam	PF00089. Trypsin. 1 hit. [Graphical view]
PROSITE	PS50240. TRYPSIN_DOM. Partial match. PS00134. TRYPSIN_HIS. Partial match. PS00135. TRYPSIN_SER. Partial match. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

CATG_RAT

Accession

Primary (citable) accession number: P17977

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 1, 1990
Last sequence update:	November 1, 1990
Last modified:	March 3, 2009
This is version 60 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HPI (Human Proteome Initiative)