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P17957

- CHS2_SOYBN

UniProt

P17957 - CHS2_SOYBN

Protein

Chalcone synthase 2

Gene

CHS2

Organism
Glycine max (Soybean) (Glycine hispida)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 87 (01 Oct 2014)
      Sequence version 1 (01 Nov 1990)
      Previous versions | rss
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    Functioni

    The primary product of this enzyme is 4,2',4',6'-tetrahydroxychalcone (also termed naringenin-chalcone or chalcone) which can under specific conditions spontaneously isomerize into naringenin.

    Catalytic activityi

    3 malonyl-CoA + 4-coumaroyl-CoA = 4 CoA + naringenin chalcone + 3 CO2.PROSITE-ProRule annotation

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei164 – 1641PROSITE-ProRule annotation

    GO - Molecular functioni

    1. naringenin-chalcone synthase activity Source: UniProtKB-EC

    GO - Biological processi

    1. flavonoid biosynthetic process Source: UniProtKB-UniPathway

    Keywords - Molecular functioni

    Acyltransferase, Transferase

    Keywords - Biological processi

    Flavonoid biosynthesis

    Enzyme and pathway databases

    UniPathwayiUPA00154.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Chalcone synthase 2 (EC:2.3.1.74)
    Alternative name(s):
    Naringenin-chalcone synthase 2
    Gene namesi
    Name:CHS2
    OrganismiGlycine max (Soybean) (Glycine hispida)
    Taxonomic identifieri3847 [NCBI]
    Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsfabidsFabalesFabaceaePapilionoideaePhaseoleaeGlycineSoja
    ProteomesiUP000008827: Chromosome 5

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 388388Chalcone synthase 2PRO_0000216063Add
    BLAST

    Expressioni

    Gene expression databases

    GenevestigatoriP17957.

    Structurei

    3D structure databases

    ProteinModelPortaliP17957.
    SMRiP17957. Positions 3-388.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the chalcone/stilbene synthases family.Curated

    Phylogenomic databases

    KOiK00660.

    Family and domain databases

    Gene3Di3.40.47.10. 2 hits.
    InterProiIPR012328. Chalcone/stilbene_synth_C.
    IPR018088. Chalcone/stilbene_synthase_AS.
    IPR001099. Chalcone/stilbene_synthase_N.
    IPR011141. Polyketide_synthase_type-III.
    IPR016039. Thiolase-like.
    IPR016038. Thiolase-like_subgr.
    [Graphical view]
    PfamiPF02797. Chal_sti_synt_C. 1 hit.
    PF00195. Chal_sti_synt_N. 1 hit.
    [Graphical view]
    PIRSFiPIRSF000451. PKS_III. 1 hit.
    SUPFAMiSSF53901. SSF53901. 2 hits.
    PROSITEiPS00441. CHALCONE_SYNTH. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    P17957-1 [UniParc]FASTAAdd to Basket

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    MVSVEEIRKA QRAEGPATVM AIGTATPPNC VDQSTYPDYY FRITNSEHMT    50
    ELKEKFKRMC DKSMIKKRYM YLNEEILKEN PSVCAYMAPS LDARQDMVVM 100
    EVPKLGKEAA TKAIKEWGQP KSKITHLIFC TTSGVDMPGA DYQLTKLLGL 150
    RPSVKRYMMY QQGCFAGGTV LRLAKDLAEN NKGARVLVVC SEITAVTFRG 200
    PTDTHLDSLV GQALFGDGAA AVIVGSDPLP VEKPLFQLVW TAQTILPDSE 250
    GAIDGHLREV GLTFHLLKDV PGLISKNIEK ALVEAFQPLG ISDYNSIFRI 300
    AHPGGPAILD QVEAKLGLKP EKMEATRHVL SEYGNMSSAC VLFILDQMRK 350
    KSIENGLGTT GEGLDWGVLF GFGPGLTVET VVLRSVTV 388
    Length:388
    Mass (Da):42,504
    Last modified:November 1, 1990 - v1
    Checksum:i634D3F1CEDC5F973
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Sequence conflicti9 – 91K → Q in CAA46590. (PubMed:8108500)Curated
    Sequence conflicti100 – 1001M → V in CAA46590. (PubMed:8108500)Curated
    Sequence conflicti299 – 2991R → W in CAA46590. (PubMed:8108500)Curated
    Sequence conflicti387 – 3871T → S in CAA46590. (PubMed:8108500)Curated

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    X52097 Genomic DNA. Translation: CAA36317.1.
    X65636 Genomic DNA. Translation: CAA46590.1.
    PIRiJQ2249.
    S16338. SYSYCN.
    RefSeqiXP_003524935.1. XM_003524887.2.

    Genome annotation databases

    EnsemblPlantsiGLYMA05G28610.1; GLYMA05G28610.1; GLYMA05G28610.
    GLYMA05G28610.2; GLYMA05G28610.2; GLYMA05G28610.
    GeneIDi100775307.
    KEGGigmx:100775307.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    X52097 Genomic DNA. Translation: CAA36317.1 .
    X65636 Genomic DNA. Translation: CAA46590.1 .
    PIRi JQ2249.
    S16338. SYSYCN.
    RefSeqi XP_003524935.1. XM_003524887.2.

    3D structure databases

    ProteinModelPortali P17957.
    SMRi P17957. Positions 3-388.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblPlantsi GLYMA05G28610.1 ; GLYMA05G28610.1 ; GLYMA05G28610 .
    GLYMA05G28610.2 ; GLYMA05G28610.2 ; GLYMA05G28610 .
    GeneIDi 100775307.
    KEGGi gmx:100775307.

    Phylogenomic databases

    KOi K00660.

    Enzyme and pathway databases

    UniPathwayi UPA00154 .

    Gene expression databases

    Genevestigatori P17957.

    Family and domain databases

    Gene3Di 3.40.47.10. 2 hits.
    InterProi IPR012328. Chalcone/stilbene_synth_C.
    IPR018088. Chalcone/stilbene_synthase_AS.
    IPR001099. Chalcone/stilbene_synthase_N.
    IPR011141. Polyketide_synthase_type-III.
    IPR016039. Thiolase-like.
    IPR016038. Thiolase-like_subgr.
    [Graphical view ]
    Pfami PF02797. Chal_sti_synt_C. 1 hit.
    PF00195. Chal_sti_synt_N. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF000451. PKS_III. 1 hit.
    SUPFAMi SSF53901. SSF53901. 2 hits.
    PROSITEi PS00441. CHALCONE_SYNTH. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Nucleotide sequence of one member of soybean chalcone synthase multi-gene family."
      Akada S., Kung S.D., Dube S.K.
      Nucleic Acids Res. 18:3398-3398(1990) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
      Strain: cv. Williams.
    2. "Nucleotide sequence and putative regulatory elements of gene 2 of the soybean (Glycine max) chalcone synthase multigene family."
      Akada S., Kung S.D., Dube S.K.
      Plant Physiol. 102:317-319(1993) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
      Strain: cv. Williams.

    Entry informationi

    Entry nameiCHS2_SOYBN
    AccessioniPrimary (citable) accession number: P17957
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: November 1, 1990
    Last sequence update: November 1, 1990
    Last modified: October 1, 2014
    This is version 87 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programPlant Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3