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P17957

- CHS2_SOYBN

UniProt

P17957 - CHS2_SOYBN

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Protein

Chalcone synthase 2

Gene
CHS2
Organism
Glycine max (Soybean) (Glycine hispida)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

The primary product of this enzyme is 4,2',4',6'-tetrahydroxychalcone (also termed naringenin-chalcone or chalcone) which can under specific conditions spontaneously isomerize into naringenin.

Catalytic activityi

3 malonyl-CoA + 4-coumaroyl-CoA = 4 CoA + naringenin chalcone + 3 CO2.

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei164 – 1641 By similarity

GO - Molecular functioni

  1. naringenin-chalcone synthase activity Source: UniProtKB-EC

GO - Biological processi

  1. flavonoid biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

Acyltransferase, Transferase

Keywords - Biological processi

Flavonoid biosynthesis

Enzyme and pathway databases

UniPathwayiUPA00154.

Names & Taxonomyi

Protein namesi
Recommended name:
Chalcone synthase 2 (EC:2.3.1.74)
Alternative name(s):
Naringenin-chalcone synthase 2
Gene namesi
Name:CHS2
OrganismiGlycine max (Soybean) (Glycine hispida)
Taxonomic identifieri3847 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsfabidsFabalesFabaceaePapilionoideaePhaseoleaeGlycineSoja
ProteomesiUP000008827: Chromosome 5

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 388388Chalcone synthase 2PRO_0000216063Add
BLAST

Expressioni

Gene expression databases

GenevestigatoriP17957.

Structurei

3D structure databases

ProteinModelPortaliP17957.
SMRiP17957. Positions 3-388.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

KOiK00660.

Family and domain databases

Gene3Di3.40.47.10. 2 hits.
InterProiIPR012328. Chalcone/stilbene_synth_C.
IPR018088. Chalcone/stilbene_synthase_AS.
IPR001099. Chalcone/stilbene_synthase_N.
IPR011141. Polyketide_synthase_type-III.
IPR016039. Thiolase-like.
IPR016038. Thiolase-like_subgr.
[Graphical view]
PfamiPF02797. Chal_sti_synt_C. 1 hit.
PF00195. Chal_sti_synt_N. 1 hit.
[Graphical view]
PIRSFiPIRSF000451. PKS_III. 1 hit.
SUPFAMiSSF53901. SSF53901. 2 hits.
PROSITEiPS00441. CHALCONE_SYNTH. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P17957-1 [UniParc]FASTAAdd to Basket

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MVSVEEIRKA QRAEGPATVM AIGTATPPNC VDQSTYPDYY FRITNSEHMT    50
ELKEKFKRMC DKSMIKKRYM YLNEEILKEN PSVCAYMAPS LDARQDMVVM 100
EVPKLGKEAA TKAIKEWGQP KSKITHLIFC TTSGVDMPGA DYQLTKLLGL 150
RPSVKRYMMY QQGCFAGGTV LRLAKDLAEN NKGARVLVVC SEITAVTFRG 200
PTDTHLDSLV GQALFGDGAA AVIVGSDPLP VEKPLFQLVW TAQTILPDSE 250
GAIDGHLREV GLTFHLLKDV PGLISKNIEK ALVEAFQPLG ISDYNSIFRI 300
AHPGGPAILD QVEAKLGLKP EKMEATRHVL SEYGNMSSAC VLFILDQMRK 350
KSIENGLGTT GEGLDWGVLF GFGPGLTVET VVLRSVTV 388
Length:388
Mass (Da):42,504
Last modified:November 1, 1990 - v1
Checksum:i634D3F1CEDC5F973
GO

Sequence conflict

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti9 – 91K → Q in CAA46590. 1 Publication
Sequence conflicti100 – 1001M → V in CAA46590. 1 Publication
Sequence conflicti299 – 2991R → W in CAA46590. 1 Publication
Sequence conflicti387 – 3871T → S in CAA46590. 1 Publication

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
X52097 Genomic DNA. Translation: CAA36317.1.
X65636 Genomic DNA. Translation: CAA46590.1.
PIRiJQ2249.
S16338. SYSYCN.
RefSeqiXP_003524935.1. XM_003524887.2.

Genome annotation databases

EnsemblPlantsiGLYMA05G28610.1; GLYMA05G28610.1; GLYMA05G28610.
GLYMA05G28610.2; GLYMA05G28610.2; GLYMA05G28610.
GeneIDi100775307.
KEGGigmx:100775307.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
X52097 Genomic DNA. Translation: CAA36317.1 .
X65636 Genomic DNA. Translation: CAA46590.1 .
PIRi JQ2249.
S16338. SYSYCN.
RefSeqi XP_003524935.1. XM_003524887.2.

3D structure databases

ProteinModelPortali P17957.
SMRi P17957. Positions 3-388.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblPlantsi GLYMA05G28610.1 ; GLYMA05G28610.1 ; GLYMA05G28610 .
GLYMA05G28610.2 ; GLYMA05G28610.2 ; GLYMA05G28610 .
GeneIDi 100775307.
KEGGi gmx:100775307.

Phylogenomic databases

KOi K00660.

Enzyme and pathway databases

UniPathwayi UPA00154 .

Gene expression databases

Genevestigatori P17957.

Family and domain databases

Gene3Di 3.40.47.10. 2 hits.
InterProi IPR012328. Chalcone/stilbene_synth_C.
IPR018088. Chalcone/stilbene_synthase_AS.
IPR001099. Chalcone/stilbene_synthase_N.
IPR011141. Polyketide_synthase_type-III.
IPR016039. Thiolase-like.
IPR016038. Thiolase-like_subgr.
[Graphical view ]
Pfami PF02797. Chal_sti_synt_C. 1 hit.
PF00195. Chal_sti_synt_N. 1 hit.
[Graphical view ]
PIRSFi PIRSF000451. PKS_III. 1 hit.
SUPFAMi SSF53901. SSF53901. 2 hits.
PROSITEi PS00441. CHALCONE_SYNTH. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Nucleotide sequence of one member of soybean chalcone synthase multi-gene family."
    Akada S., Kung S.D., Dube S.K.
    Nucleic Acids Res. 18:3398-3398(1990) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: cv. Williams.
  2. "Nucleotide sequence and putative regulatory elements of gene 2 of the soybean (Glycine max) chalcone synthase multigene family."
    Akada S., Kung S.D., Dube S.K.
    Plant Physiol. 102:317-319(1993) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: cv. Williams.

Entry informationi

Entry nameiCHS2_SOYBN
AccessioniPrimary (citable) accession number: P17957
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1990
Last sequence update: November 1, 1990
Last modified: September 3, 2014
This is version 86 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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