ID   FMCD_PSEAI              Reviewed;         150 AA.
AC   P17837;
DT   01-AUG-1990, integrated into UniProtKB/Swiss-Prot.
DT   01-AUG-1990, sequence version 1.
DT   27-MAR-2024, entry version 98.
DE   RecName: Full=Fimbrial protein;
DE   AltName: Full=Pilin;
DE   Flags: Precursor;
GN   Name=pilA; Synonyms=fimA;
OS   Pseudomonas aeruginosa.
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Pseudomonadales;
OC   Pseudomonadaceae; Pseudomonas.
OX   NCBI_TaxID=287;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=CD;
RX   PubMed=2893774; DOI=10.1128/iai.56.3.665-672.1988;
RA   Pasloske B.L., Joffe A.M., Sun Q., Volpel K., Paranchych W., Eftekhar F.,
RA   Speert D.P.;
RT   "Serial isolates of Pseudomonas aeruginosa from a cystic fibrosis patient
RT   have identical pilin sequences.";
RL   Infect. Immun. 56:665-672(1988).
CC   -!- SUBUNIT: The pili are polar flexible filaments of about 5.4 nanometers
CC       diameter and 2.5 micrometers average length; they consist of only a
CC       single polypeptide chain arranged in a helical configuration of five
CC       subunits per turn in the assembled pilus.
CC   -!- SUBCELLULAR LOCATION: Fimbrium. Membrane {ECO:0000255}; Single-pass
CC       membrane protein {ECO:0000255}.
CC   -!- SIMILARITY: Belongs to the N-Me-Phe pilin family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAA25945.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; M24281; AAA25945.1; ALT_INIT; Genomic_DNA.
DR   PIR; A43504; A43504.
DR   RefSeq; WP_031636800.1; NZ_WIGE01000040.1.
DR   AlphaFoldDB; P17837; -.
DR   SMR; P17837; -.
DR   PATRIC; fig|287.1494.peg.5534; -.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0009289; C:pilus; IEA:UniProtKB-SubCell.
DR   GO; GO:0007155; P:cell adhesion; IEA:InterPro.
DR   Gene3D; 3.30.700.10; Glycoprotein, Type 4 Pilin; 1.
DR   InterPro; IPR012902; N_methyl_site.
DR   InterPro; IPR001082; Pilin.
DR   InterPro; IPR045584; Pilin-like.
DR   NCBIfam; TIGR02532; IV_pilin_GFxxxE; 1.
DR   PANTHER; PTHR30093; GENERAL SECRETION PATHWAY PROTEIN G; 1.
DR   PANTHER; PTHR30093:SF34; TYPE IV MAJOR PILIN PROTEIN PILA; 1.
DR   Pfam; PF07963; N_methyl; 1.
DR   Pfam; PF00114; Pilin; 1.
DR   SUPFAM; SSF54523; Pili subunits; 1.
DR   PROSITE; PS00409; PROKAR_NTER_METHYL; 1.
PE   3: Inferred from homology;
KW   Disulfide bond; Fimbrium; Membrane; Methylation; Transmembrane;
KW   Transmembrane helix.
FT   PROPEP          1..6
FT                   /note="Leader sequence"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01070"
FT                   /id="PRO_0000024168"
FT   CHAIN           7..150
FT                   /note="Fimbrial protein"
FT                   /id="PRO_0000024169"
FT   TRANSMEM        7..27
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   MOD_RES         7
FT                   /note="N-methylphenylalanine"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01070"
FT   DISULFID        134..147
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   150 AA;  15743 MW;  E14316996F270F3C CRC64;
     MKAQKGFTLI ELMIVVAIIG ILAAIAIPQY QNYVARSEGA SALATINPLK TTVEESLSRG
     IAGSKILIGT TASTADTTYV GIDEKANKLG TVAVTIKDTG DGTVKFTFAT GQSSPKNAGK
     EITLNRTAEG VWTCTSTQEE MFIPKGCNKP
//