Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

P17818

- CHSY_MATIN

UniProt

P17818 - CHSY_MATIN

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Chalcone synthase

Gene

CHS

Organism
Matthiola incana (Common stock) (Cheiranthus incanus)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at transcript leveli

Functioni

The primary product of this enzyme is 4,2',4',6'-tetrahydroxychalcone (also termed naringenin-chalcone or chalcone) which can under specific conditions spontaneously isomerize into naringenin.

Catalytic activityi

3 malonyl-CoA + 4-coumaroyl-CoA = 4 CoA + naringenin chalcone + 3 CO2.PROSITE-ProRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei168 – 1681PROSITE-ProRule annotation

GO - Molecular functioni

  1. naringenin-chalcone synthase activity Source: UniProtKB-EC

GO - Biological processi

  1. flavonoid biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

Acyltransferase, Transferase

Keywords - Biological processi

Flavonoid biosynthesis

Enzyme and pathway databases

UniPathwayiUPA00154.

Names & Taxonomyi

Protein namesi
Recommended name:
Chalcone synthase (EC:2.3.1.74)
Alternative name(s):
Naringenin-chalcone synthase
Gene namesi
Name:CHS
OrganismiMatthiola incana (Common stock) (Cheiranthus incanus)
Taxonomic identifieri3724 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeAnchonieaeMatthiola

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Initiator methioninei1 – 11RemovedBy similarity
Chaini2 – 394393Chalcone synthasePRO_0000216005Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei2 – 21N-acetylvalineBy similarity

Keywords - PTMi

Acetylation

Structurei

3D structure databases

ProteinModelPortaliP17818.
SMRiP17818. Positions 7-394.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the chalcone/stilbene synthases family.Curated

Family and domain databases

Gene3Di3.40.47.10. 2 hits.
InterProiIPR012328. Chalcone/stilbene_synth_C.
IPR018088. Chalcone/stilbene_synthase_AS.
IPR001099. Chalcone/stilbene_synthase_N.
IPR011141. Polyketide_synthase_type-III.
IPR016039. Thiolase-like.
IPR016038. Thiolase-like_subgr.
[Graphical view]
PfamiPF02797. Chal_sti_synt_C. 1 hit.
PF00195. Chal_sti_synt_N. 1 hit.
[Graphical view]
PIRSFiPIRSF000451. PKS_III. 1 hit.
SUPFAMiSSF53901. SSF53901. 2 hits.
PROSITEiPS00441. CHALCONE_SYNTH. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P17818-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MVMGATSLDE IRKAQRADGP AGILGIGTAN PANHVIQAEY PDYYFRITNS
60 70 80 90 100
EHMTDLKEKF QRMCDKSMIR KRHMHLTEDF LKENPNMCAY MAPSLDARQD
110 120 130 140 150
IVVVEVPKLG KEAAVRAIKE WGQPKSKITH LVFCTTSGVD MPGADYQLTK
160 170 180 190 200
LLGLRPSVKR LMMYQQGCFA GGTVLRLAKD LAENNRGARV LVVCSEITAV
210 220 230 240 250
TFRGPSDTHL DSLVGQALFS DGAAALIVGS DPDTSVGEKP IFEMVSAAQT
260 270 280 290 300
ILPDSDGAID GHLREVGLTF HLLKDVPGLI SKNIEKSLEE AFKPLGISDW
310 320 330 340 350
NSLFWIAHPG GPAILDQVEI KLGLKAEKMR ATRHVLSEYG NMSSACVLFI
360 370 380 390
LDEMRKKSAQ DGVATTGEGL EWGVLFGFGP GLTVETVVLR SVPL
Length:394
Mass (Da):42,969
Last modified:August 1, 1990 - v1
Checksum:iEF2DA6C0FB550714
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X17577 mRNA. Translation: CAA35600.1.
PIRiS11876. SYJCCS.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X17577 mRNA. Translation: CAA35600.1 .
PIRi S11876. SYJCCS.

3D structure databases

ProteinModelPortali P17818.
SMRi P17818. Positions 7-394.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Enzyme and pathway databases

UniPathwayi UPA00154 .

Family and domain databases

Gene3Di 3.40.47.10. 2 hits.
InterProi IPR012328. Chalcone/stilbene_synth_C.
IPR018088. Chalcone/stilbene_synthase_AS.
IPR001099. Chalcone/stilbene_synthase_N.
IPR011141. Polyketide_synthase_type-III.
IPR016039. Thiolase-like.
IPR016038. Thiolase-like_subgr.
[Graphical view ]
Pfami PF02797. Chal_sti_synt_C. 1 hit.
PF00195. Chal_sti_synt_N. 1 hit.
[Graphical view ]
PIRSFi PIRSF000451. PKS_III. 1 hit.
SUPFAMi SSF53901. SSF53901. 2 hits.
PROSITEi PS00441. CHALCONE_SYNTH. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Isolation and sequence analysis of a chalcone synthase cDNA of Matthiola incana R. Br. (Brassicaceae)."
    Epping B., Kittel M., Ruhnau B., Hemleben V.
    Plant Mol. Biol. 14:1061-1063(1990) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA].
    Tissue: Petal.

Entry informationi

Entry nameiCHSY_MATIN
AccessioniPrimary (citable) accession number: P17818
Entry historyi
Integrated into UniProtKB/Swiss-Prot: August 1, 1990
Last sequence update: August 1, 1990
Last modified: October 1, 2014
This is version 78 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3