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P17815 (MASY_RICCO) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 74. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Malate synthase, glyoxysomal

EC=2.3.3.9
OrganismRicinus communis (Castor bean)
Taxonomic identifier3988 [NCBI]
Taxonomic lineageEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsfabidsMalpighialesEuphorbiaceaeAcalyphoideaeAcalypheaeRicinus

Protein attributes

Sequence length567 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Catalytic activity

Acetyl-CoA + H2O + glyoxylate = (S)-malate + CoA.

Pathway

Carbohydrate metabolism; glyoxylate cycle; (S)-malate from isocitrate: step 2/2.

Subcellular location

Glyoxysome.

Sequence similarities

Belongs to the malate synthase family.

Ontologies

Keywords
   Biological processGlyoxylate bypass
Tricarboxylic acid cycle
   Cellular componentGlyoxysome
Peroxisome
   Molecular functionTransferase
Gene Ontology (GO)
   Biological_processglyoxylate cycle

Inferred from electronic annotation. Source: UniProtKB-UniPathway

tricarboxylic acid cycle

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular_componentglyoxysome

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionmalate synthase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 567567Malate synthase, glyoxysomal
PRO_0000166872

Regions

Motif565 – 5673Microbody targeting signal Potential

Sites

Active site1821Proton acceptor By similarity
Active site4681Proton donor By similarity

Sequences

Sequence LengthMass (Da)Tools
P17815 [UniParc].

Last modified August 1, 1990. Version 1.
Checksum: 3888DCAF87CD36E2

FASTA56764,263
        10         20         30         40         50         60 
MRYDTYGDSA PIKKTGAGYD VPEGVDIRGR YDGEFAKILT RDALQFVADL QREFRNRIRY 

        70         80         90        100        110        120 
AIECRKEAKS RYNAGALPGF EHPATKYIRE GEWTCAPVPP AVADRKVEIT GPVERKMIIN 

       130        140        150        160        170        180 
ALNSGAKVFM ADFEDALSPS WENLMRGQVN LRDAVNGTIS FHDKARNRVY KLNDQIAKLF 

       190        200        210        220        230        240 
VRPRGWHLPE AHILIDGEPA TGCLVDFGLY FYHNYAAFRR NQGAGYGPFF YLPKMEHSRE 

       250        260        270        280        290        300 
AKIWNCVFEK AEKMAGIERG SIRATVLIET LPAVFQMNEI LYELRDHSVG LNCGRWDYIF 

       310        320        330        340        350        360 
SYVKTFQAHP DRPLPDRVQV GMTQHFMKSY SDLLVWTCHR RGVHAMGGMA AQIPIRDDPA 

       370        380        390        400        410        420 
ANKAALELVR KDKLREVKAG HDGTWAAHPG LIPACMEVFA NNMGNTPHQI QAMKREDAAN 

       430        440        450        460        470        480 
ITEEDLIQRP RGVRTLEGLR LNTRVGIQYL AAWLTGTGSV PLYNLMEDAA TAEISRVQNW 

       490        500        510        520        530        540 
QWLKYGVELD GDGLGVKVTF DLLGRVVEDE MARIEREVGK EKFKKGMYKE ACKMFVRQCA 

       550        560 
APTLDDFLTL DAYNNIVIHY PKGSSRL 

« Hide

References

[1]"Nucleotide sequence analysis of a cDNA clone encoding malate synthase of castor bean (Ricinus communis) reveals homology to DAL7, a gene involved in allantoin degradation in Saccharomyces cerevisiae."
Rodriguez D., Ginger R.S., Baker A., Northcote D.H.
Plant Mol. Biol. 15:501-504(1990) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [MRNA].
Tissue: Endosperm.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
X52806 mRNA. Translation: CAA36994.1.
PIRSYCSM2. S14677.

3D structure databases

ProteinModelPortalP17815.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Enzyme and pathway databases

UniPathwayUPA00703; UER00720.

Family and domain databases

InterProIPR011076. Malate_synth-like.
IPR006252. Malate_synthA.
IPR001465. Malate_synthase.
IPR019830. Malate_synthase_CS.
[Graphical view]
PANTHERPTHR21631:SF1. PTHR21631:SF1. 1 hit.
PfamPF01274. Malate_synthase. 1 hit.
[Graphical view]
PIRSFPIRSF001363. Malate_synth. 1 hit.
SUPFAMSSF51645. SSF51645. 1 hit.
TIGRFAMsTIGR01344. malate_syn_A. 1 hit.
PROSITEPS00510. MALATE_SYNTHASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameMASY_RICCO
AccessionPrimary (citable) accession number: P17815
Entry history
Integrated into UniProtKB/Swiss-Prot: August 1, 1990
Last sequence update: August 1, 1990
Last modified: February 19, 2014
This is version 74 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways