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Protein

Elongation factor 1-alpha

Gene
N/A
Organism
Solanum lycopersicum (Tomato) (Lycopersicon esculentum)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi14 – 21GTPBy similarity8
Nucleotide bindingi91 – 95GTPBy similarity5
Nucleotide bindingi153 – 156GTPBy similarity4

GO - Molecular functioni

Keywordsi

Molecular functionElongation factor
Biological processProtein biosynthesis
LigandGTP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Elongation factor 1-alpha
Short name:
EF-1-alpha
OrganismiSolanum lycopersicum (Tomato) (Lycopersicon esculentum)
Taxonomic identifieri4081 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaeasteridslamiidsSolanalesSolanaceaeSolanoideaeSolaneaeSolanumLycopersicon
Proteomesi
  • UP000004994 Componenti: Chromosome 6

Subcellular locationi

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000909381 – 448Elongation factor 1-alphaAdd BLAST448

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei2895-glutamyl glycerylphosphorylethanolamineBy similarity1
Modified residuei3625-glutamyl glycerylphosphorylethanolamineBy similarity1

Keywords - PTMi

Phosphoprotein

Proteomic databases

PaxDbiP17786
PRIDEiP17786

Expressioni

Gene expression databases

ExpressionAtlasiP17786 baseline and differential

Interactioni

Protein-protein interaction databases

STRINGi4081.Solyc06g009970.2.1

Structurei

3D structure databases

ProteinModelPortaliP17786
SMRiP17786
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini5 – 230tr-type GAdd BLAST226

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni14 – 21G1By similarity8
Regioni70 – 74G2By similarity5
Regioni91 – 94G3By similarity4
Regioni153 – 156G4By similarity4
Regioni194 – 196G5By similarity3

Sequence similaritiesi

Phylogenomic databases

eggNOGiKOG0052 Eukaryota
COG5256 LUCA
InParanoidiP17786
KOiK03231
OMAiPAKETKM
OrthoDBiEOG093608Z1

Family and domain databases

HAMAPiMF_00118_A EF_Tu_A, 1 hit
InterProiView protein in InterPro
IPR004161 EFTu-like_2
IPR031157 G_TR_CS
IPR027417 P-loop_NTPase
IPR000795 TF_GTP-bd_dom
IPR009000 Transl_B-barrel_sf
IPR009001 Transl_elong_EF1A/Init_IF2_C
IPR004539 Transl_elong_EF1A_euk/arc
IPR004160 Transl_elong_EFTu/EF1A_C
PfamiView protein in Pfam
PF00009 GTP_EFTU, 1 hit
PF03144 GTP_EFTU_D2, 1 hit
PF03143 GTP_EFTU_D3, 1 hit
PRINTSiPR00315 ELONGATNFCT
SUPFAMiSSF50447 SSF50447, 1 hit
SSF50465 SSF50465, 1 hit
SSF52540 SSF52540, 1 hit
TIGRFAMsiTIGR00483 EF-1_alpha, 1 hit
PROSITEiView protein in PROSITE
PS00301 G_TR_1, 1 hit
PS51722 G_TR_2, 1 hit

Sequencei

Sequence statusi: Complete.

P17786-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGKEKIHISI VVIGHVDSGK STTTGHLIYK LGGIDKRVIE RFEKEAAEMN
60 70 80 90 100
KRSFKYAWVL DKLKAERERG ITIDIALWKF ETTKYYCTVI DAPGHRDFIK
110 120 130 140 150
NMITGTSQAD CAVLIIDSTT GGFEAGISKD GQTREHALLA FTLGVKQMIC
160 170 180 190 200
CCNKMDATTP KYSKARYDEI VKEVSSYLKK VGYNPDKIPF VPISGFEGDN
210 220 230 240 250
MIERSTNLDW YKGPTLLEAL DQINEPKRPS DKPLRLPLQD VYKIGGIGTV
260 270 280 290 300
PVGRVETGVI KPGMVVTFGP TGLTTEVKSV EMHHEALQEA LPGDNVGFNV
310 320 330 340 350
KNVAVKDLKR GYVASNSKDD PAKGAASFTA QVIIMNHPGQ IGNGYAPVLD
360 370 380 390 400
CHTSHIAVKF AEILTKIDRR SGKELEKEPK FLKNGDAGMV KMIPTKPMVV
410 420 430 440
ETFAEYPPLG RFAVRDMRQT VAVGVVKNVD KKDPTGAKVT KAAQKKGK
Length:448
Mass (Da):49,288
Last modified:August 1, 1990 - v1
Checksum:iC8E8BF6C1C0A7F56
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X53043 Genomic DNA Translation: CAA37212.1
X14449 mRNA Translation: CAA32618.1
PIRiS10507
RefSeqiNP_001234035.1, NM_001247106.2
XP_004240579.1, XM_004240531.3
UniGeneiLes.17723
Les.19575

Genome annotation databases

EnsemblPlantsiSolyc06g005060.2.1; Solyc06g005060.2.1; Solyc06g005060.2
Solyc06g009970.2.1; Solyc06g009970.2.1; Solyc06g009970.2
GeneIDi101244084
544055
GrameneiSolyc06g005060.2.1; Solyc06g005060.2.1; Solyc06g005060.2
Solyc06g009970.2.1; Solyc06g009970.2.1; Solyc06g009970.2
KEGGisly:101244084
sly:544055

Similar proteinsi

Entry informationi

Entry nameiEF1A_SOLLC
AccessioniPrimary (citable) accession number: P17786
Entry historyiIntegrated into UniProtKB/Swiss-Prot: August 1, 1990
Last sequence update: August 1, 1990
Last modified: May 23, 2018
This is version 111 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

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