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Protein

Genome polyprotein

Gene
N/A
Organism
Bean yellow mosaic virus
Status
Reviewed-Annotation score: Annotation score: 5 out of 5-Protein inferred from homologyi

Functioni

Capsid protein: involved in aphid transmission, cell-to-cell and systemis movement, encapsidation of the viral RNA and in the regulation of viral RNA amplification.
Nuclear inclusion protein B: an RNA-dependent RNA polymerase that plays an essential role in the virus replication.
Helper component proteinase: required for aphid transmission and also has proteolytic activity. Only cleaves a Gly-Gly dipeptide at its own C-terminus. Interacts with virions and aphid stylets. Acts as a suppressor of RNA-mediated gene silencing, also known as post-transcriptional gene silencing (PTGS), a mechanism of plant viral defense that limits the accumulation of viral RNAs. May have RNA-binding activity (By similarity).By similarity
Cytoplasmic inclusion protein: has helicase activity. It may be involved in replication (By similarity).By similarity
Both 6K peptides are indispensable for virus replication.By similarity
Nuclear inclusion protein A: has RNA-binding and proteolytic activities.

Catalytic activityi

Hydrolyzes glutaminyl bonds, and activity is further restricted by preferences for the amino acids in P6 - P1' that vary with the species of potyvirus, e.g. Glu-Xaa-Xaa-Tyr-Xaa-Gln-|-(Ser or Gly) for the enzyme from tobacco etch virus. The natural substrate is the viral polyprotein, but other proteins and oligopeptides containing the appropriate consensus sequence are also cleaved.
Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1).PROSITE-ProRule annotation
Hydrolyzes a Gly-|-Gly bond at its own C-terminus, commonly in the sequence -Tyr-Xaa-Val-Gly-|-Gly, in the processing of the potyviral polyprotein.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei192 – 1921For P1 proteinase activityBy similarity
Active sitei201 – 2011For P1 proteinase activitySequence analysis
Active sitei627 – 6271For helper component proteinase activityPROSITE-ProRule annotation
Active sitei700 – 7001For helper component proteinase activityPROSITE-ProRule annotation
Active sitei2067 – 20671For nuclear inclusion protein A activityPROSITE-ProRule annotation
Active sitei2102 – 21021For nuclear inclusion protein A activityPROSITE-ProRule annotation
Active sitei2172 – 21721For nuclear inclusion protein A activityPROSITE-ProRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi1227 – 12348ATPPROSITE-ProRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Helicase, Hydrolase, Nucleotidyltransferase, Protease, RNA-directed RNA polymerase, Suppressor of RNA silencing, Thiol protease, Transferase

Keywords - Biological processi

Viral RNA replication

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Protein family/group databases

MEROPSiC04.008.

Names & Taxonomyi

Protein namesi
Recommended name:
Genome polyprotein
Cleaved into the following 10 chains:
Alternative name(s):
N-terminal protein
Helper component proteinase (EC:3.4.22.45)
Short name:
HC-pro
6 kDa protein 1
Short name:
6K1
6 kDa protein 2
Short name:
6K2
Alternative name(s):
VPg
Nuclear inclusion protein A (EC:3.4.22.44)
Short name:
NI-a
Short name:
NIa
Alternative name(s):
49 kDa proteinase
Short name:
49 kDa-Pro
NIa-pro
Nuclear inclusion protein B (EC:2.7.7.48)
Short name:
NI-b
Short name:
NIb
Alternative name(s):
RNA-directed RNA polymerase
Capsid protein
Short name:
CP
Alternative name(s):
Coat protein
OrganismiBean yellow mosaic virus
Taxonomic identifieri12197 [NCBI]
Taxonomic lineageiVirusesssRNA virusesssRNA positive-strand viruses, no DNA stagePotyviridaePotyvirus
Virus hostiArachis hypogaea (Peanut) [TaxID: 3818]
Canna [TaxID: 4627]
Crotalaria [TaxID: 3828]
Eustoma [TaxID: 52517]
Freesia [TaxID: 58987]
Gladiolus [TaxID: 49747]
Glycine max (Soybean) (Glycine hispida) [TaxID: 3847]
Lupinus luteus (European yellow lupin) [TaxID: 3873]
Medicago sativa (Alfalfa) [TaxID: 3879]
Papaver somniferum (Opium poppy) [TaxID: 3469]
Phaseolus vulgaris (Kidney bean) (French bean) [TaxID: 3885]
Pisum sativum (Garden pea) [TaxID: 3888]
Robinia pseudoacacia (Black locust) [TaxID: 35938]
Trifolium hybridum (Alsike clover) [TaxID: 74517]
Trifolium incarnatum (Crimson clover) [TaxID: 60916]
Trifolium pratense (Red clover) [TaxID: 57577]
Trifolium repens (Creeping white clover) [TaxID: 3899]
Trifolium subterraneum (Subterranean clover) [TaxID: 3900]
Trifolium vesiculosum [TaxID: 97047]
Trigonella foenum-graecum (Fenugreek) [TaxID: 78534]
Vicia faba (Broad bean) (Faba vulgaris) [TaxID: 3906]
Vicia sativa (Spring vetch) (Tare) [TaxID: 3908]
Proteomesi
  • UP000007620 Componenti: Genome

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Capsid protein, Helical capsid protein, Virion

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 30563056Genome polyproteinPRO_0000419996Add
BLAST
Chaini1 – 284284P1 proteinaseSequence analysisPRO_0000040256Add
BLAST
Chaini285 – 741457Helper component proteinaseSequence analysisPRO_0000040257Add
BLAST
Chaini742 – 1089348Protein P3Sequence analysisPRO_0000040258Add
BLAST
Chaini1090 – 1142536 kDa protein 1By similarityPRO_0000040259Add
BLAST
Chaini1143 – 1777635Cytoplasmic inclusion proteinBy similarityPRO_0000040260Add
BLAST
Chaini1778 – 1830536 kDa protein 2By similarityPRO_0000040261Add
BLAST
Chaini1831 – 2021191Viral genome-linked proteinBy similarityPRO_0000040262Add
BLAST
Chaini2022 – 2264243Nuclear inclusion protein ABy similarityPRO_0000040263Add
BLAST
Chaini2265 – 2783519Nuclear inclusion protein BBy similarityPRO_0000040264Add
BLAST
Chaini2784 – 3056273Capsid proteinBy similarityPRO_0000040265Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei1893 – 18931O-(5'-phospho-RNA)-tyrosineBy similarity

Post-translational modificationi

VPg is uridylylated by the polymerase and is covalently attached to the 5'-end of the genomic RNA. This uridylylated form acts as a nucleotide-peptide primer for the polymerase (By similarity).By similarity
Potyviral RNA is expressed as two polyproteins which undergo post-translational proteolytic processing. Genome polyprotein is processed by NIa-pro, P1 and HC-pro proteinases resulting in the production of at least ten individual proteins. P3N-PIPO polyprotein is cleaved by P1 and HC-pro proteinases resulting in the production of three individual proteins. The P1 proteinase and the HC-pro cleave only their respective C-termini autocatalytically. 6K1 is essential for proper proteolytic separation of P3 from CI (By similarity).By similarity

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sitei284 – 2852Cleavage; by P1 proteinaseSequence analysis
Sitei741 – 7422Cleavage; by autolysisPROSITE-ProRule annotation
Sitei1100 – 11012Cleavage; by NIa-proBy similarity
Sitei1152 – 11532Cleavage; by NIa-proBy similarity
Sitei1787 – 17882Cleavage; by NIa-proBy similarity
Sitei1840 – 18412Cleavage; by NIa-proBy similarity
Sitei2021 – 20222Cleavage; by NIa-proBy similarity
Sitei2274 – 22752Cleavage; by NIa-proBy similarity
Sitei2793 – 27942Cleavage; by NIa-proBy similarity

Keywords - PTMi

Covalent protein-RNA linkage, Phosphoprotein

Structurei

3D structure databases

ProteinModelPortaliP17765.
SMRiP17765. Positions 2030-2243.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini619 – 741123Peptidase C6PROSITE-ProRule annotationAdd
BLAST
Domaini1214 – 1366153Helicase ATP-bindingPROSITE-ProRule annotationAdd
BLAST
Domaini1385 – 1544160Helicase C-terminalPROSITE-ProRule annotationAdd
BLAST
Domaini2022 – 2240219Peptidase C4PROSITE-ProRule annotationAdd
BLAST
Domaini2507 – 2630124RdRp catalyticPROSITE-ProRule annotationAdd
BLAST

Motif

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Motifi335 – 3384Involved in interaction with stylet and aphid transmissionBy similarity
Motifi593 – 5953Involved in virions binding and aphid transmissionBy similarity
Motifi1316 – 13194DECH box
Motifi1871 – 18788Nuclear localization signalSequence analysis

Domaini

The N-terminus of helper component proteinase is involved in interaction with stylets. The central part is involved in interaction with virions and the C-terminus is involved in cell-to cell movement of the virus.

Sequence similaritiesi

Contains 1 helicase ATP-binding domain.PROSITE-ProRule annotation
Contains 1 helicase C-terminal domain.PROSITE-ProRule annotation
Contains 1 peptidase C4 domain.PROSITE-ProRule annotation
Contains 1 peptidase C6 domain.PROSITE-ProRule annotationCurated
Contains 1 peptidase S30 domain.Curated
Contains 1 RdRp catalytic domain.PROSITE-ProRule annotation

Family and domain databases

Gene3Di3.40.50.300. 2 hits.
InterProiIPR011545. DEAD/DEAH_box_helicase_dom.
IPR001456. HC-pro.
IPR031159. HC_PRO_CPD_dom.
IPR014001. Helicase_ATP-bd.
IPR001650. Helicase_C.
IPR027417. P-loop_NTPase.
IPR002540. Pept_S30_P1_potyvir.
IPR009003. Peptidase_S1_PA.
IPR001592. Poty_coat.
IPR001730. Potyv_NIa-pro_dom.
IPR013648. PP_Potyviridae.
IPR001205. RNA-dir_pol_C.
IPR007094. RNA-dir_pol_PSvirus.
[Graphical view]
PfamiPF00270. DEAD. 1 hit.
PF00271. Helicase_C. 1 hit.
PF00863. Peptidase_C4. 1 hit.
PF00851. Peptidase_C6. 1 hit.
PF01577. Peptidase_S30. 1 hit.
PF00767. Poty_coat. 1 hit.
PF08440. Poty_PP. 1 hit.
PF00680. RdRP_1. 1 hit.
[Graphical view]
PRINTSiPR00966. NIAPOTYPTASE.
SMARTiSM00487. DEXDc. 1 hit.
SM00490. HELICc. 1 hit.
[Graphical view]
SUPFAMiSSF50494. SSF50494. 1 hit.
SSF52540. SSF52540. 2 hits.
PROSITEiPS51744. HC_PRO_CPD. 1 hit.
PS51192. HELICASE_ATP_BIND_1. 1 hit.
PS51194. HELICASE_CTER. 1 hit.
PS51436. POTYVIRUS_NIA_PRO. 1 hit.
PS50507. RDRP_SSRNA_POS. 1 hit.
[Graphical view]

Sequences (2)i

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

This entry describes 2 isoformsi produced by ribosomal frameshifting. AlignAdd to basket

Isoform Genome polyprotein (identifier: P17765-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MTTINIGTIP VVINQNADTQ MGEGTKNIFP IVKDFVDPFA DLEMRCAERV
60 70 80 90 100
KRMGELCFSK KGRYITMIPK PDYIKAREKE QREEELNFQN SEHVLNSLDT
110 120 130 140 150
TCTPEHHSSR NNGMQVSFKT QHYKRTFRKP RIQAKKRDLK GQHTIHYVAK
160 170 180 190 200
ELLSIVKKRD MVLEVVDKRK HANFATFRRY GKTYGMHITL NHMVRKRRRV
210 220 230 240 250
DVTLNKLMTE IAMHCAIPFE CLNTLTLRKG HSGLVLQTET VPNVHKIKSK
260 270 280 290 300
ITIVRGVVNE GNIPVLIDAR KKLSGRDMST IREFSAGDLF WKGYNQTFID
310 320 330 340 350
NRPTDLNHQC TSDLNVTQCG SVMALLTLAL FPCGRITCKK CVENFLNQNN
360 370 380 390 400
KERFNNASVF INQVIQLLEK GFSEFKHSKE ILLMFKERLQ MENPATDQCM
410 420 430 440 450
EIAKATAALP EAPFSHIKEI NNVLLKYGSL SNEEVGGASK HLLEVVRYIR
460 470 480 490 500
NRTDSIQRND LSKFRNKISS KTHINLDLMC DNQLDKNANF VWGQRAYHAK
510 520 530 540 550
RFLSNYFNEI NPSEGYDKFI FRKLPNGARE LAIGRLIMPT NFEAFREQMK
560 570 580 590 600
GKMIDNGPIG KDCVSRMRGS FCYPCCCTTD DVGTAVISDF KMPTKYHLVL
610 620 630 640 650
GGNDLAKYIK LPTDTTGNMY IAKDGFCHIN IFFAMLVNVS EEKSKDFTKM
660 670 680 690 700
VRDQIMPKLG EWPTMMDVAT ACWQLTVWFP DTLSAELPRI LVDHKLGIMH
710 720 730 740 750
VLDSYGSISA GYHVLKANIV SQLIKFASDD LESELKYYRV GGDCNFGSRV
760 770 780 790 800
RIDTKFLLKS IYRPDLLERI IEHEPFVLVL AMQSPAVLLA LFNSASLEKA
810 820 830 840 850
VQYWMHREMQ VSHIMTLLAV LASNVSASKL LTTQFEIIEA SAPQILAEMD
860 870 880 890 900
KVHLPMHSIH SANVFLMNMS ESRETDKTID ELGFYSFKKS SRILMEKTLM
910 920 930 940 950
ADLEEQWQGL GLLERLSLIK RSWRVRAKYS SFAIQREEPG IRDKFTTSLK
960 970 980 990 1000
LSGAQIKQQL LAQKDQAVHF VERRIEGTKK FVANQSISLI KMCLPRLADI
1010 1020 1030 1040 1050
VNILTVIALL NAILAFMLDH IKRFNEARRI AQEKKEKQHL KELNTLYNKY
1060 1070 1080 1090 1100
WDNEKPTYLE FKSDVIEKLP HTLATFEKYY FEDDKYTFQA KPNDMVALEK
1110 1120 1130 1140 1150
IIAVTALVLM IFDAERSDCV YKVLNKLKGI LSTTTQDAYR FQSLDTSKTL
1160 1170 1180 1190 1200
LEEKEMTIDF EINEGEVKAF SGTQTTFSEW WDNQLQNGNV ITHYRTEGQF
1210 1220 1230 1240 1250
MEFTRANAQP VANEIAHNDA HDILVRGAVG SGKSTGLPFY LSNKGKVLMI
1260 1270 1280 1290 1300
ESTRPLAENV FKQLKSEPFY ASPTLRMRGT TSYGASPITI MTSGYALHYY
1310 1320 1330 1340 1350
ANNPAMMKEY KFVIIDECHV HDANAIAFVS LLKEYSFDGK LIKVSATPPG
1360 1370 1380 1390 1400
REVEFTTQYP VTLVTEESLS FEQFVSQQGT GANCDMLDVC DNILVYVASY
1410 1420 1430 1440 1450
NEVDQLSKML LDRGHIVTKV DGRTMKNGKT EIESKGSRSK RHFIVATNII
1460 1470 1480 1490 1500
ENGVTLDIEG VVDFGLKVVP ELDVDNRLMR YTKQNVSYGE RIQRLGRVGR
1510 1520 1530 1540 1550
HKAGKALRIG VTEKGLVKPP SVITTEAAFY CFAYGLPVMA EGVTPSLLSK
1560 1570 1580 1590 1600
CTVQQARSMM SFELPIMYTV NLVRFDGTMH PSVHNLLKPY KLRDSNVVLN
1610 1620 1630 1640 1650
KMAIPHGNVR NWPTVRDFKC MGVRIDAPED TRVPFHARDI PDKLHKEIFE
1660 1670 1680 1690 1700
VCCKYKGDAG FSKLNVVNAC KIAYTLQTDP SSIQRTIKIL DELIAREQQK
1710 1720 1730 1740 1750
REYFQNVANT SCAGSSYSLS NIINAIRARS TSDYTQENLS VLHSARAQLL
1760 1770 1780 1790 1800
EFKNINSDFS NLSTLSEFGA LECLQFESLQ EISKHLQLKG HWNKPVLIQD
1810 1820 1830 1840 1850
FLIAAGVLGG GCWMLYQYFK QETSKAFVFQ GKNRRTKQKL RFRDARDMKG
1860 1870 1880 1890 1900
RMEVYADEGT IVENFGSKYT KKGKVRGTTT GMGTKTRRFT NMYGFDPTEY
1910 1920 1930 1940 1950
SFARYLDPIT GETLDEQPIT NLNLVSEHFQ EMRRKYRENE IMESQQFAAN
1960 1970 1980 1990 2000
PRIEAYFVKD AGQKVLKVDL TPHKPLLYSD KFGNIMGYPE REGELRQTGA
2010 2020 2030 2040 2050
AEFIDPKELP EPKESTDFDF ESLSKIGGLR DYNPIAANVC LLENESAEYC
2060 2070 2080 2090 2100
DEIYGIGYGN VIITNQHLFR HNNGELTIKS KHGTFKCKNT CALKLLPIEG
2110 2120 2130 2140 2150
HDLLLIQMPK DFPVFPQKLR FREPTHEDKI VLVSTNFQEK SFSSVVSESS
2160 2170 2180 2190 2200
NISRVKQANF FKHWISTVAG QCGNPMVSTK DGFIVGIHSL TAVSGDLNVF
2210 2220 2230 2240 2250
TSIPPNFEDE VLKQMSKKSW CCGWKLNMSQ IGWDGIKIVD DQPKDPFPVS
2260 2270 2280 2290 2300
KMVGLLNDLQ LSFQSAKNTK WLLERAHGNI KAVAQASSAL VTKHVVKGKC
2310 2320 2330 2340 2350
RLFEVYLTTD EEAEKFFRPL MGAYQKSRLN KEAYVKDLMK YATPIEVGLV
2360 2370 2380 2390 2400
DTRCFERSFE KVQNMLELKG FSKCNYVTYG PDILSALNMK AAMGALYSGK
2410 2420 2430 2440 2450
KKDHFSEISE EKFDNILQAS CERLYSGRMG VWNGSLKAEL RPQEKVLANK
2460 2470 2480 2490 2500
TRSFTAAPID TLLAGKVCVD DFNNKFYSLH LKIPSTVGIT KFYGGWDRLL
2510 2520 2530 2540 2550
DSLPDGWVYC DADGSQFDSS LTPYLLNAVL EMRLRLMEEW DLGEQMLKNL
2560 2570 2580 2590 2600
YTEIVYTPIL TPDGTIVKKF KGNNSGQPST VVDNTLMVIM AVYYAAEKLG
2610 2620 2630 2640 2650
IKGNLEDTLV FFANGDDLLI AIKPECESYL DKFEGLFSEL GLKYDFSSRT
2660 2670 2680 2690 2700
KNKGDLWFMS HRGIQIDGMW IPKLEEERIV SILEWDRAIQ PEHRLEAICA
2710 2720 2730 2740 2750
AMIEAWGYPT LLNHIRKFYL WVLGQAPYSQ LSAEGKAPYI SEVALKHLYT
2760 2770 2780 2790 2800
EEKVTPTELE RYNIALIDCF ESESDEVLTC RFQSDQEQLN AGEEKKDKRK
2810 2820 2830 2840 2850
KNEGDPNKDS EGQSVRQIVP DRDVNAGTVG TFSVPRLKKI AGKLNIPKIG
2860 2870 2880 2890 2900
GKIVLNLDHL LEYNPPQDDI SNVIATQAQF EAWYNGVKQA YEVEDSQMGI
2910 2920 2930 2940 2950
ILNGLMVWCI ENGTSGDLQG EWTMMDGEEQ VTYPLKPILD NAKPTFRQIM
2960 2970 2980 2990 3000
SHFSEVAEAY IEKRNATERY MPRYGLQRNL TDYGLARYAF DFYKLTSRTP
3010 3020 3030 3040 3050
VRAREAHMQM KAAAVRGKST RLFGLDGNVG TDEENTERHT AGDVNRDMHT

MLGVRI
Note: Produced by conventional translation.
Length:3,056
Mass (Da):347,722
Last modified:June 21, 2005 - v2
Checksum:iBA4D2F2D2D4624B3
GO
Isoform P3N-PIPO polyprotein (identifier: P0CJ95-1) [UniParc]FASTAAdd to basket
The sequence of this isoform can be found in the external entry P0CJ95.
Isoforms of the same protein are often annotated in two different entries if their sequences differ significantly.
Note: Produced by -1 ribosomal frameshifting in P3 ORF.
Length:975
Mass (Da):111,115
GO

Natural variant

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Natural varianti2775 – 27751D → G.
Natural varianti2805 – 28051D → N.
Natural varianti2855 – 28551L → F.
Natural varianti2862 – 28621E → K.
Natural varianti2897 – 28971Q → R.
Natural varianti2975 – 29751G → E.
Natural varianti2994 – 29941K → E.
Natural varianti3017 – 30171G → A.

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY192568 Genomic RNA. Translation: AAP30002.1.
D00490 Genomic RNA. Translation: BAA00378.1.
PIRiJU0115.

Keywords - Coding sequence diversityi

Ribosomal frameshifting

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY192568 Genomic RNA. Translation: AAP30002.1.
D00490 Genomic RNA. Translation: BAA00378.1.
PIRiJU0115.

3D structure databases

ProteinModelPortaliP17765.
SMRiP17765. Positions 2030-2243.
ModBaseiSearch...
MobiDBiSearch...

Protein family/group databases

MEROPSiC04.008.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Family and domain databases

Gene3Di3.40.50.300. 2 hits.
InterProiIPR011545. DEAD/DEAH_box_helicase_dom.
IPR001456. HC-pro.
IPR031159. HC_PRO_CPD_dom.
IPR014001. Helicase_ATP-bd.
IPR001650. Helicase_C.
IPR027417. P-loop_NTPase.
IPR002540. Pept_S30_P1_potyvir.
IPR009003. Peptidase_S1_PA.
IPR001592. Poty_coat.
IPR001730. Potyv_NIa-pro_dom.
IPR013648. PP_Potyviridae.
IPR001205. RNA-dir_pol_C.
IPR007094. RNA-dir_pol_PSvirus.
[Graphical view]
PfamiPF00270. DEAD. 1 hit.
PF00271. Helicase_C. 1 hit.
PF00863. Peptidase_C4. 1 hit.
PF00851. Peptidase_C6. 1 hit.
PF01577. Peptidase_S30. 1 hit.
PF00767. Poty_coat. 1 hit.
PF08440. Poty_PP. 1 hit.
PF00680. RdRP_1. 1 hit.
[Graphical view]
PRINTSiPR00966. NIAPOTYPTASE.
SMARTiSM00487. DEXDc. 1 hit.
SM00490. HELICc. 1 hit.
[Graphical view]
SUPFAMiSSF50494. SSF50494. 1 hit.
SSF52540. SSF52540. 2 hits.
PROSITEiPS51744. HC_PRO_CPD. 1 hit.
PS51192. HELICASE_ATP_BIND_1. 1 hit.
PS51194. HELICASE_CTER. 1 hit.
PS51436. POTYVIRUS_NIA_PRO. 1 hit.
PS50507. RDRP_SSRNA_POS. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiPOLG_BYMV
AccessioniPrimary (citable) accession number: P17765
Secondary accession number(s): Q65887, Q6Y1D8
Entry historyi
Integrated into UniProtKB/Swiss-Prot: August 1, 1990
Last sequence update: June 21, 2005
Last modified: September 7, 2016
This is version 118 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Peptidase families
    Classification of peptidase families and list of entries
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.